Human Insulin+insulin Isophane
About Human Insulin+insulin Isophane
Human Insulin+insulin Isophane is an injectable prescription medication used to control high blood sugar in adults and children with diabetes mellitus. This dual-acting injection helps manage blood glucose by mimicking the body's natural insulin release. Keeping your blood sugar levels within a healthy range helps prevent long-term complications associated with diabetes.
To get the best results, you must inject Human Insulin+insulin Isophane consistently and exactly as prescribed, typically 15 to 30 minutes before a meal. Because Human Insulin+insulin Isophane contains both rapid-acting and longer-acting components, timing your injection with your food intake is crucial to prevent your blood sugar from dropping too low. Combining this treatment with a structured meal plan and regular physical activity is essential for managing your condition effectively.
While using Human Insulin+insulin Isophane, you may experience mild side effects, with low blood sugar (hypoglycemia) and injection site reactions being the most common. It is important to watch for signs of severe low blood sugar, such as sudden sweating, shaking, confusion, or dizziness. If you experience these or any signs of a severe allergic reaction, contact your doctor immediately.
Before starting Human Insulin+insulin Isophane, talk to your doctor if you have kidney or liver problems, heart failure, or if you are using other diabetes medicines. Do not inject Human Insulin+insulin Isophane if you are currently experiencing an episode of low blood sugar or if you have ever had an allergic reaction to this medication. If you have heart failure, taking certain oral diabetes medicines alongside this injection can worsen fluid retention, so a medical evaluation is required.
Certain medicines, alcohol use, and smoking can alter how this injection works, which may lead to unpredictable blood sugar levels. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your healthcare provider to adjust your treatment plan safely. Always talk to your doctor or pharmacist before making any changes to your therapy.
Uses of Human Insulin+insulin Isophane
• Diabetes Management: Human Insulin+insulin Isophane is primarily used to regulate blood glucose levels in individuals with diabetes mellitus, helping to keep them within a healthy range.
• Postprandial Blood Sugar Control: Human Insulin+insulin Isophane effectively manages postprandial (after meal) blood sugar spikes through its combination of intermediate and short-acting insulin.
• Type 1 and Type 2 Diabetes Treatment: Human Insulin+insulin Isophane is prescribed for patients with Type 1 and Type 2 diabetes who are unable to achieve adequate glycemic control with oral hypoglycemic agents alone.
Medicinal Benefits
Human Insulin+insulin Isophane helps manage blood sugar levels in people with diabetes by providing both rapid and longer-lasting insulin action. By maintaining stable blood sugar control throughout the day, it supports overall health and reduces the risk of diabetes-related complications.
Benefits may include:
- Helps control both mealtime and between-meal blood sugar levels.
- Provides a combination of fast-acting and intermediate-acting insulin for more consistent blood sugar management.
- Helps maintain blood sugar within the target range throughout the day.
- Reduces the risk of long-term diabetes complications affecting the eyes, kidneys, nerves, and heart.
- May reduce the number of injections needed compared with using separate insulin preparations.
- Supports an active and healthy lifestyle when used alongside a balanced diet, regular physical activity, and routine blood sugar monitoring.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
- Human Insulin+insulin Isophane should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks).
- It should never be administered intravenously or in the vein.
- If you are not well-trained to self-administer it, ask your healthcare professional to administer it.
Storage
Side Effects of Human Insulin+insulin Isophane
Common Side Effects (Usually mild):
- Low blood sugar (hypoglycemia), causing shakiness, sweating, or headache
- Redness, swelling, or itching at the injection site
- Thickening or pitting of the skin at the injection site
- Mild weight gain
Serious Side Effects (Call a doctor right away):
- Signs of a severe allergic reaction, such as a rash, swelling of the face, tongue, or throat, and difficulty breathing
- Severe low blood sugar leading to confusion, vision changes, or loss of consciousness
- Signs of low potassium levels, such as muscle cramps, weakness, or an irregular heartbeat
Medicines Containing this Salt
View AllDrug Warnings
- Inspect the medicine before use: Always check the injection before each use. After mixing, the liquid should appear uniformly cloudy and should not contain visible clumps, flakes, or particles.
- Do not share injection equipment: Never share your injection pens, vials, or needles with anyone else, even if the needle has been changed, as this may spread serious infections.
- Rotate injection sites regularly: Change your injection site each day to help prevent fatty lumps from developing, which can affect how well Human Insulin+insulin Isophane is absorbed.
- Avoid injecting into damaged skin: Do not inject into areas that are tender, bruised, red, hard, scarred, or otherwise irritated.
- Keep an adequate supply available: Always keep a spare vial or pen and extra syringes or needles available to help avoid missing doses if your supplies run low.
Drug Interactions
- Other diabetes medicines, ACE inhibitors, or certain antidepressants: Taking these medicines alongside Human Insulin+insulin Isophane may increase the risk of low blood sugar (hypoglycemia).
- Corticosteroids, thyroid hormones, or certain diuretics: These medicines may increase blood sugar levels and reduce the effectiveness of Human Insulin+insulin Isophane, requiring dose adjustments.
- Beta-blockers: These medicines may mask common symptoms of low blood sugar, such as a fast heartbeat or shakiness, making hypoglycemia more difficult to recognize.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Human Insulin+insulin Isophane to avoid unpleasant side effects. Alcohol may cause increased drowsiness.
Pregnancy
consult your doctorIt is safe to use Human Insulin+insulin Isophane during pregnancy if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.
Breast Feeding
consult your doctorIt is safe to use Human Insulin+insulin Isophane by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.
Driving
cautionHuman Insulin+insulin Isophane may cause drowsiness and hypoglycemia (low blood sugar). Therefore, drive only if you are alert.
Liver
cautionHuman Insulin+insulin Isophane should be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.
Kidney
cautionHuman Insulin+insulin Isophane should be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.
Children
safe if prescribedHuman Insulin+insulin Isophane can be given safely to children provided the dose has been prescribed by a child specialist.
Habit Forming
Diet & Lifestyle Advise
- Maintain a consistent meal schedule: Avoid skipping meals after taking Human Insulin+insulin Isophane, as regular meal times can help prevent sudden drops in blood sugar levels.
- Monitor your blood sugar regularly: Check your blood sugar as recommended, especially before meals, after exercise, and before bedtime, and keep a record to share with your doctor.
- Be prepared for low blood sugar: Always carry a fast-acting source of sugar, such as glucose tablets, fruit juice, or hard candy, to help manage unexpected episodes of low blood sugar.
- Stay physically active safely: Incorporate regular, moderate exercise into your routine, but check your blood sugar before physical activity, as exercise may lower your insulin requirements.
- Limit alcohol consumption: Reduce your alcohol intake, as alcohol can affect blood sugar levels unpredictably and increase the risk of severe hypoglycemia.
Special Advise
If you feel any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.
Patients Concern
Disease/Condition Glossary
Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.
FAQs
Human Insulin+insulin Isophane is used for the treatment of‚ both type 1 and type 2 diabetes mellitus.
Human Insulin+insulin Isophane suppresses the production of sugar in the liver and‚ facilitates the reuptake of sugar in the fat and muscle cells, thereby Human Insulin+insulin Isophane ensures rapid and consistent sugar control.
Human Insulin+insulin Isophane may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Human Insulin+insulin Isophane. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.
Do not stop taking Human Insulin+insulin Isophane without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Human Insulin+insulin Isophane for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Human Insulin+insulin Isophane.
Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Human Insulin+insulin Isophane is taken along with other antidiabetic medicines.
Side effects of Human Insulin+insulin Isophane include allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Symptoms of high blood sugar include feeling thirsty, increased urination, weakness or tiredness, blurred vision and weight loss.
Human Insulin+insulin Isophane is to be injected below the skin (subcutaneously). The best areas to inject Human Insulin+insulin Isophane are on your stomach, upper arm, upper thigh, or buttocks.
Unopened vials are to be refrigerated between 2°C and 8°C. Opened vials (in-use) may be stored not above 25ºC for a maximum of 4 weeks. The used needle should be placed in a puncture-resistant disposable container and disposed of properly as directed by your healthcare provider.
No, you should inject Human Insulin+insulin Isophane exactly as prescribed by your doctor, usually 15 to 30 minutes before a meal to ensure it coordinates with your food intake. Talk to your doctor to establish your daily schedule.
Do not use Human Insulin+insulin Isophane. Properly mixed Human Insulin+insulin Isophane should look uniformly cloudy. If you see clear liquid, solid clumps, or particles that do not mix after gently rolling, contact your pharmacist for a replacement.
No, you must never freeze Human Insulin+insulin Isophane. If Human Insulin+insulin Isophane accidentally freezes, it loses its effectiveness and must be discarded safely. Store unopened packages in the refrigerator instead.
Rotating your injection sites helps prevent the development of fatty lumps or pits in your skin. Injecting into these damaged areas can prevent your body from absorbing Human Insulin+insulin Isophane correctly, leading to unstable blood sugar levels. Talk to your doctor if you notice skin changes.
Yes, alcohol can unpredictably alter your blood sugar levels and significantly increase your risk of severe low blood sugar. It can also mask the symptoms of hypoglycemia. Talk to your doctor about whether it is safe for you to drink alcohol.
Managing blood sugar is highly critical during pregnancy and breastfeeding, and insulin is often the preferred choice. Your dose may need to be adjusted during these periods, so talk to your doctor to update your treatment plan.
If you feel symptoms of mild low blood sugar, eat or drink 15 grams of fast-acting sugar immediately, such as half a cup of fruit juice, three glucose tablets, or hard candy. Check your blood sugar again in 15 minutes, and talk to your doctor if your levels remain low.
Yes, you can travel with your medicine. Keep your current, in-use pen or vial at room temperature and protect it from extreme heat or direct sunlight. Carry unopened spares in an insulated travel bag with a cold pack, making sure Human Insulin+insulin Isophane does not touch the ice directly. Talk to your pharmacist for travel tips.
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