Fluconazole+ivermectin
About Fluconazole+ivermectin
Fluconazole+ivermectin is a prescription medicine that combines an antifungal medicine with an antiparasitic medicine. It is used to treat certain fungal and parasitic infections when your doctor decides that both medicines are appropriate. Treating infections early and following the prescribed treatment plan can help reduce symptoms and support recovery.
Take Fluconazole+ivermectin exactly as prescribed by your doctor. Follow the recommended dose and complete the full course, even if you start feeling better. Maintaining good personal hygiene and following your doctor's advice can also help improve treatment outcomes and reduce the chance of reinfection.
Like all medicines, Fluconazole+ivermectin may cause side effects, although not everyone experiences them. Common side effects include nausea, headache, stomach discomfort, dizziness, and loss of appetite. Seek immediate medical attention if you develop severe skin rash, blistering, swelling of the face or throat, difficulty breathing, or yellowing of the skin or eyes.
Before taking Fluconazole+ivermectin, tell your doctor if you have liver disease, kidney disease, heart rhythm problems, or if you have ever had an allergic reaction to fluconazole, ivermectin, or similar medicines. Fluconazole+ivermectin is generally not recommended for children weighing less than 15 kg unless specifically advised by a healthcare professional.
Inform your doctor about all prescription medicines, over-the-counter medicines, herbal products, vitamins, and supplements you are taking, as some medicines may interact with Fluconazole+ivermectin. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Fluconazole+ivermectin.
Uses of Fluconazole+ivermectin
Medicinal Benefits
Fluconazole+ivermectin helps treat certain fungal and parasitic infections by combining two medicines with different mechanisms of action. It helps eliminate the infection, relieve symptoms, and support faster recovery when used as prescribed.
Benefits may include:
• Helps stop the growth of susceptible fungi causing fungal infections.
• Helps eliminate susceptible parasites responsible for parasitic infections.
• Relieves itching, redness, irritation, and discomfort associated with infection.
• Supports faster recovery by treating the underlying cause of the infection.
• Helps reduce the risk of the infection worsening or returning when the full treatment course is completed.
• Improves overall comfort and quality of life by effectively clearing the infection.
Directions for Use
- Take Fluconazole+ivermectin with or without food or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Fluconazole+ivermectin
Common Side Effects (Usually mild):
- Nausea or mild stomach discomfort
- Mild headache
- Dizziness or lightheadedness
- Temporary loss of appetite
Serious Side Effects (Call a doctor right away):
- Signs of an allergic reaction, such as skin rash, hives, swelling of the face, lips, or throat, and difficulty breathing
- Signs of liver damage, including yellowing of the skin or eyes, dark urine, severe stomach pain, or persistent nausea
- Severe, peeling skin rash or blistering
- Extreme dizziness or fainting spells
Drug Warnings
- Take Fluconazole+ivermectin as prescribed: Take Fluconazole+ivermectin exactly as directed by your doctor and complete the full course of treatment, even if your symptoms improve before Fluconazole+ivermectin is finished.
- Follow food instructions carefully: Take Fluconazole+ivermectin according to your doctor's instructions or the product label. Fluconazole may be taken with or without food, while ivermectin is generally taken on an empty stomach.
- Inform your healthcare provider about all medicines: Tell your doctor about all prescription medicines, over-the-counter products, herbal supplements, vitamins, and dietary supplements you are taking before starting treatment to help prevent drug interactions.
- Avoid alcohol during treatment: Do not drink alcohol while taking Fluconazole+ivermectin unless your doctor advises otherwise, as it may increase the risk of side effects.
- Use caution during activities requiring alertness: If you feel dizzy or drowsy after taking Fluconazole+ivermectin, avoid driving, operating machinery, or performing tasks that require full attention until you feel well again.
- Consult your doctor if: Your symptoms do not improve, return after treatment, or become worse. Also contact your doctor if you develop fever, rash, itching, swollen lymph nodes, or flu-like symptoms that become severe during treatment, as these may occur while parasites are being eliminated.
- Seek immediate medical attention if: You develop difficulty breathing, a severe skin rash with blistering, swelling of the face, lips, tongue, or throat, or signs of liver problems such as yellowing of the skin or eyes or dark urine.
Drug Interactions
- Blood thinners (e.g., warfarin, apixaban): Taking these medicines alongside Fluconazole+ivermectin may increase the risk of bleeding. Your doctor may monitor your blood clotting tests more closely.
- Heart rhythm medicines (e.g., amiodarone): Using these medicines with Fluconazole+ivermectin may increase the risk of serious irregular heart rhythms.
- Anti-seizure medicines (e.g., phenytoin): Fluconazole+ivermectin may increase phenytoin levels and the risk of side effects. Your doctor may adjust the dose or monitor treatment.
- Gastrointestinal motility medicines (e.g., cisapride): Do not use these medicines with Fluconazole+ivermectin, as the combination may cause serious heart rhythm problems.
- Cholesterol-lowering medicines (statins) (e.g., simvastatin, atorvastatin): Fluconazole+ivermectin may increase the risk of muscle pain and muscle damage when taken with these medicines.
- Medicines metabolized by liver enzymes (CYP enzymes): Fluconazole+ivermectin may alter the levels of medicines processed by liver enzymes. Your doctor may monitor your treatment or adjust the dose if needed.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionNo interaction was found. However, alcohol inhibits the immune system's ability to prepare and defend the body against hazardous microorganisms, increasing the risk of serious illnesses.
Pregnancy
cautionPlease consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionIt is unknown whether Fluconazole+ivermectin is excreted in human milk. Fluconazole+ivermectin is given to breastfeeding mothers if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are breastfeeding.
Driving
cautionFluconazole+ivermectin may cause drowsiness or asthenia (weakness). Therefore, avoid driving if you experience these symptoms after taking Fluconazole+ivermectin.
Liver
cautionRegular liver function tests are recommended for patients with pre-existing liver issues, particularly if they are taking medication for an extended period of time. Treatment should be stopped if liver enzyme levels drop or stay high. Hence, if you have liver problems, inform your doctor before taking Fluconazole+ivermectin.
Kidney
cautionDue to inadequate drug clearance, patients with renal impairment may be more vulnerable to fluconazole side effects. When taking the medication in multiple doses, patients with moderate to severe kidney impairment (CrCl <= 50 mL/min) should adjust their dosage. So, if you have kidney problems, inform your doctor before taking Fluconazole+ivermectin.
Children
cautionLimited information about using Fluconazole+ivermectin in children is available, so please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Avoid alcohol: Do not drink alcohol while taking Fluconazole+ivermectin, as it can significantly increase the risk of liver damage and dizziness.
- Practice strict hygiene: Wash all clothing, towels, and bedsheets in hot water to kill any remaining parasites and prevent reinfection.
- Keep skin dry: Fungi thrive in warm, moist environments. Keep infected skin areas clean and dry throughout the day.
- Stay hydrated: Drink plenty of water to help your kidneys and liver process and clear Fluconazole+ivermectin efficiently.
Special Advise
- If the infection persists or worsens after using Fluconazole+ivermectin for 1 week, please consult a doctor.
- If you experience diarrhea during the use of Fluconazole+ivermectin, drink lots of water and consult your doctor, do not use any anti-diarrheal medicine on your own.
Patients Concern
Disease/Condition Glossary
Fungal infection: Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may affect the skin and spread into bones, tissues, organs, or the whole body. It may be contagious (spread from one person to another). The symptoms of a fungal infection include skin rash, darkening of the skin, peeling, itching, deformed toenail, or vaginal discharge. Antifungal medicines are usually used to treat fungal infections.
Parasitic infections: Parasitic worms, also called intestinal worms or helminths, are infections caused by parasites (micro-organisms) that live in or on another host/organism. These infections can occur due to consuming contaminated water, food or soil, contact with contaminated faeces, poor sanitisation and poor hygiene. Symptoms may include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools). Fluconazole+ivermectin is used in treating infections of the roundworms, hookworms, threadworms, whipworms, and pinworms.
FAQs
Fluconazole+ivermectin is used to treat Fungal and Parasitic Infections.
Fluconazole+ivermectin is a combination of two drugs: Fluconazole and Ivermectin. Fluconazole+ivermectin treats fungal and parasitic infections caused by certain parasites, such as head lice, scabies, and certain worms. Fluconazole+ivermectin works by inhibiting fungal growth and multiplication and paralyzing and killing parasites.
Fluconazole+ivermectin may cause diarrhoea as a temporary adverse effect. However, if the condition persists or worsens, please consult your doctor.
Fungal infections are contagious so that they can pass from person to person through skin-to-skin contact, through clothes or contact with contaminated surfaces and objects.
Fluconazole+ivermectin is a prescribed medication to treat specific medical conditions only. It should be used only if prescribed by the doctor.
Follow your doctor's instructions or the product label. Fluconazole can usually be taken with or without food, while ivermectin is generally taken on an empty stomach (about 1 hour before or 2 hours after a meal) for more consistent absorption.
Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting Fluconazole+ivermectin. Your doctor will decide whether Fluconazole+ivermectin is suitable for you after weighing the expected benefits and possible risks.
It is best to avoid alcohol during treatment because it may increase the risk of liver-related side effects and may worsen dizziness or drowsiness.
Yes. Some people may experience dizziness while taking Fluconazole+ivermectin. If this happens, avoid driving, riding a bicycle, or operating machinery until you feel well again.
A Mazzotti reaction is a temporary immune response that may occur after ivermectin kills certain parasites, especially those causing filarial infections. Symptoms may include fever, rash, itching, swollen lymph nodes, muscle aches, or joint pain. Contact your doctor promptly if these symptoms occur or become severe.
Fluconazole+ivermectin should only be given to children if prescribed by a healthcare professional. Ivermectin is generally not recommended for children weighing less than 15 kg unless a specialist advises otherwise.
If your symptoms do not improve after completing the prescribed treatment, become worse during treatment, or return after initially improving, consult your doctor for further evaluation. Additional tests or a different treatment may be needed.
Fluconazole+ivermectin can interact with certain medicines. Tell your doctor about all prescription medicines, over-the-counter medicines, herbal products, vitamins, and supplements you take. In particular, inform your doctor if you take medicines such as amiodarone, warfarin, phenytoin, cisapride, or certain cholesterol-lowering medicines (statins). Your doctor can advise whether Fluconazole+ivermectin is appropriate and whether any dose adjustments or monitoring are needed.
