Efonidipine+metoprolol
About Efonidipine+metoprolol
Efonidipine+metoprolol is a prescription oral medication used to manage high blood pressure and prevent chest pain known as angina. By keeping these cardiovascular conditions under control, this medicine helps reduce your overall risk of suffering from future heart attacks and strokes. It is designed to provide long-term cardiovascular support when used exactly as directed by your healthcare provider.
To achieve the best results, you must take Efonidipine+metoprolol consistently every single day, ideally at the same time. You can take this medication with or without food, but it is important to choose one method and stick to it consistently to keep drug levels stable in your body. Incorporating heart-healthy lifestyle changes, such as reducing your daily salt intake and engaging in regular, moderate exercise, will significantly help improve your treatment outcomes.
While taking Efonidipine+metoprolol, some people may experience mild side effects, including dizziness, headaches, a slightly slower heart rate, or mild ankle swelling. These are often manageable, but if you experience serious symptoms such as severe shortness of breath, unexplained sudden weight gain, or worsening chest pain, you must consult your doctor immediately.
Before starting Efonidipine+metoprolol, talk to your doctor if you have a history of asthma, liver damage, diabetes, or kidney problems. Do not take this if you have a very slow heart rate, severe heart failure, cardiogenic shock, or certain serious heart rhythm conditions. Always provide your complete health history to your healthcare provider to ensure this medicine is safe for your specific condition.
This medicine can interact with alcohol, which can excessively lower your blood pressure and cause severe dizziness. Smoking can also reduce the overall effectiveness of this treatment. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist before starting Efonidipine+metoprolol to determine if it is appropriate for you.
Uses of Efonidipine+metoprolol
Medicinal Benefits
Efonidipine+metoprolol helps protect your heart and blood vessels by controlling blood pressure and reducing the heart's workload. The key benefits of this medicine include:
- Helps regulate blood pressure, reducing strain on your heart, blood vessels, and kidneys, while lowering the long-term risk of serious complications such as stroke and heart attack.
- Helps reduce the frequency and severity of angina (chest pain) episodes, allowing you to perform daily activities, walk, and exercise with greater comfort and confidence.
- Improves overall cardiovascular efficiency by decreasing the heart's workload and oxygen demand, helping you feel less fatigued during routine physical activities.
Directions for Use
- Efonidipine+metoprolol can be taken with or without food, as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow Efonidipine+metoprolol as a whole with a glass of water.
- Do not break, crush, or chew it.
Storage
Side Effects of Efonidipine+metoprolol
Common Side Effects (Usually mild):
- Dizziness or lightheadedness
- Headache
- Slightly slow heart rate
- Mild swelling in the ankles or feet
- Feeling unusually tired or weak
Serious Side Effects (Call a doctor right away):
- Severe shortness of breath or difficulty breathing
- Sudden, unexplained weight gain
- Fainting spells or severe lightheadedness
- Extremely slow, irregular, or pounding heartbeat
- Coldness, tingling, or blue discoloration in your hands or feet
- Signs of a severe allergic reaction, such as swelling of the face, lips, tongue, or throat, accompanied by a skin rash or itching
Medicines Containing this Salt
View AllDrug Warnings
- Rise slowly: Stand up gradually from sitting or lying down positions to avoid sudden dizziness and prevent falls.
- Do not stop taking abruptly: Stopping Efonidipine+metoprolol suddenly can cause a dangerous rebound rise in blood pressure or worsen chest pain.
- If treatment needs to be stopped, your doctor will gradually taper the dose under medical supervision to reduce the risk of witdrawal effects.
- Check your pulse regularly: If your resting heart rate drops below 50 to 55 beats per minute, contact your doctor before taking your next dose.
- Inform medical professionals: Let your dentist, surgeon, or anesthesiologist know you are taking Efonidipine+metoprolol before undergoing any medical or dental procedures.
- Avoid driving initially: Do not drive or operate heavy machinery until you know how this medication affects your alertness and balance.
Drug Interactions
- Other blood pressure medicines: Taking Efonidipine+metoprolol with other blood pressure lowering treatments can cause an excessive drop in blood pressure.
- Calcium channel blockers or beta-blockers: Combining this with other medications in these classes can dangerously slow your heart rate.
- NSAIDs (like ibuprofen): May reduce the effectiveness of Efonidipine+metoprolol in lowering your blood pressure.
- Heart rhythm medicines (like amiodarone): May increase the risk of serious slow heart rates and rhythm disturbances.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeIt is not to consume alcohol since it may worsen the side effects like dizziness and also increase blood pressure.
Pregnancy
cautionEfonidipine+metoprolol should not used by pregnant women and women suspected of being pregnant unless the benefits to the mother outweigh the risks to the foetus.
Breast Feeding
cautionEfonidipine+metoprolol should not used if you are breastfeeding unless the benefits surpass the risks to your baby.
Driving
cautionDo not drive or operate machinery as Efonidipine+metoprolol can influence the ability to drive and use machines. Dizziness or drowsiness may occasionally occur when taking Efonidipine+metoprolol.
Liver
cautionEfonidipine+metoprolol should be used cautiously in patients with liver disease. Inform your doctor if you have a liver impairment before taking Efonidipine+metoprolol. Your doctor may adjust the dose accordingly.
Kidney
cautionLimited data is available on using Efonidipine+metoprolol in patients with kidney disease. If you have kidney problems, inform your doctor before taking Efonidipine+metoprolol.
Children
cautionEfonidipine+metoprolol is not recommended in children and adolescents under 18 years due to a lack of information for this age group.
Habit Forming
Diet & Lifestyle Advise
- Reduce sodium intake: Avoid high-sodium foods and limit salt in your cooking to help manage blood pressure levels naturally.
- Limit alcohol consumption: Avoid or significantly limit alcohol, as it can interact with Efonidipine+metoprolol to cause an excessive, dangerous drop in blood pressure.
- Stay active within safe limits: Engage in moderate, low-impact exercise like walking, but consult your doctor before starting any intense physical routine.
- Avoid grapefruit products: Some components in this medication may interact with grapefruit or grapefruit juice, leading to increased drug levels and side effects.
- Monitor your blood pressure at home: Keep a regular log of your blood pressure and heart rate to share with your doctor during check-ups.
Special Advise
- Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
- Efonidipine+metoprolol may affect patients with hepatic impairment; hence, it is used cautiously, and Liver function monitoring and Liver Function Tests are advised to monitor the liver enzyme changes.
- Your doctor may advise you to get a regular kidney function test and blood examinations for potassium levels and other electrolytes while using Efonidipine+metoprolol to rule out any renal impairment.
- Grapefruit juice and grapefruit should not be consumed by people taking Efonidipine+metoprolol. This is because grapefruit and grapefruit juice can increase the blood levels of the active ingredient amlodipine in Efonidipine+metoprolol, which can cause an unpredictable increase in the blood pressure-lowering effect of Efonidipine+metoprolol.
Patients Concern
Disease/Condition Glossary
Blood pressure: Blood pressure measures the force our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor. Systolic pressure is the pressure with which the heart pumps blood. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
Efonidipine+metoprolol is used to treat High blood pressure (hypertension).
Efonidipine+metoprolol is a combination medicine containing Efonidipine and Metoprolol. Efonidipine works by relaxing blood vessels so that blood passes through them more easily. Metoprolol works by blocking beta receptors in the heart, making the heart beat slowly and with less force. It decreases the pressure at which blood is pumped out of the heart and throughout the body.
You should use Efonidipine+metoprolol in dose and duration as the doctor advises. Do not stop taking Efonidipine+metoprolol without consulting your doctor, as it may lead to a sudden rise in blood pressure and increase the risk of heart attack and stroke. The discontinuation should be done gradually under the supervision of the doctor.
You are not recommended to stop taking Efonidipine+metoprolol on your own. You are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility that your doctor may lower the dosage.
Consult your doctor before taking Efonidipine+metoprolol if you have hyperthyroidism, as it might mask the symptoms or make it difficult to recognise the signs of excess thyroid hormone in the body (thyrotoxicosis).
It's unlikely that Efonidipine+metoprolol affects fertility in men or women. However, there's not enough evidence to say for certain. For the best advice, consult your doctor.
High blood pressure during pregnancy increases the following risks: Less blood flows to the placenta. The fetus may receive less oxygen and nutrients if the placenta doesn't get enough blood. This can result in slow growth (intrauterine growth restriction), low birth weight, or preterm birth.
Yes, Efonidipine+metoprolol can cause dizziness, especially when rising quickly from a sitting or lying position. To prevent this, stand up slowly and hold onto a stable surface. Talk to your doctor if dizziness persists.
It is highly recommended to avoid or limit alcohol while taking Efonidipine+metoprolol. Alcohol can interact with this medicine to cause a sudden drop in blood pressure, leading to extreme dizziness or fainting. Talk to your doctor for advice.
Efonidipine+metoprolol is generally not recommended during pregnancy as it may cause harm to the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor immediately about safer alternatives.
Efonidipine+metoprolol contains a beta-blocker component that naturally slows down your heart rate. Checking your pulse helps ensure your heart rate does not drop dangerously low. If it falls below 50 beats per minute, talk to your doctor.
Mild ankle swelling can sometimes occur with this type of medication. However, if the swelling is sudden, painful, or accompanied by shortness of breath, it could indicate a more serious condition. Talk to your doctor right away.
Yes, Efonidipine+metoprolol can mask the warning symptoms of low blood sugar, such as a rapid heart rate or palpitations. If you have diabetes, monitor your blood sugar closely while taking this medication and talk to your doctor about managing your treatment safely.

