Cyproterone+ethinylestradiol+folic Acid
About Cyproterone+ethinylestradiol+folic Acid
Cyproterone+ethinylestradiol+folic Acid is a prescription medication used to treat moderate to severe acne sensitive to male hormones and excessive facial or body hair growth in women. It works by regulating hormone levels to help control these conditions while also providing folic acid. Although it also helps prevent pregnancy, it is prescribed primarily to treat hormone-related conditions rather than as a routine contraceptive.
To get the best results, you must take Cyproterone+ethinylestradiol+folic Acid consistently every day at the same time, either with or without food. Making healthy dietary changes, such as eating a balanced diet and staying hydrated, can further support your skin health. Using a gentle skincare routine alongside this treatment will also help improve your results.
While taking Cyproterone+ethinylestradiol+folic Acid, you may experience mild, temporary side effects like nausea or breast tenderness. However, you must seek immediate medical care if you notice signs of serious complications, such as sudden chest pain or shortness of breath. Always keep your doctor informed of any unusual symptoms you experience during your treatment.
Do not take this if you have a history of blood clots, severe liver damage, or hormone-related cancers like breast cancer. It is also not suitable for anyone who is pregnant, planning to become pregnant, or breastfeeding. Talk to your doctor about your complete medical history before starting this medication.
Some medicines, such as certain antiseizure treatments or antibiotics, can make Cyproterone+ethinylestradiol+folic Acid less effective. Avoid smoking while taking this medication because it significantly increases your risk of serious heart and blood vessel problems, including blood clots. It is also wise to limit alcohol intake to avoid putting extra strain on your liver.
Uses of Cyproterone+ethinylestradiol+folic Acid
Medicinal Benefits
Cyproterone+ethinylestradiol+folic Acid helps manage hormone-related symptoms while supporting overall reproductive health. Its benefits include:
- Improves Hormonal Acne: Helps reduce androgen-related acne by decreasing the effects of male hormones on the skin, leading to clearer skin with continued use.
- Reduces Excess Hair Growth: Helps slow the growth of unwanted facial and body hair associated with conditions such as polycystic ovary syndrome (PCOS).
- Regulates Menstrual Cycles: Helps make menstrual periods more regular and may reduce menstrual discomfort in women with hormonal imbalance.
- Provides Contraceptive Benefits: When taken correctly, it also helps prevent pregnancy while treating hormone-related conditions.
- Supports Folate Levels: The folic acid component helps maintain adequate folate levels, which is beneficial for women of reproductive age.
Directions for Use
- Cyproterone+ethinylestradiol+folic Acid can be taken with or without food as prescribed by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
- Swallow it as a whole with a glass of water.
- Do not chew, crush, or break it.
Storage
Side Effects of Cyproterone+ethinylestradiol+folic Acid
Common Side Effects (Usually mild)
- Mild nausea or stomach upset
- Breast tenderness or slight swelling
- Headaches or mild mood changes
- Slight weight changes
Serious Side Effects (Consult your doctor right away)
- Sudden pain, warmth, or swelling in one of your legs (signs of a blood clot)
- Severe chest pain or sudden shortness of breath
- Yellowing of your skin or eyes, which may point to liver damage
- Severe allergic reactions, such as swelling of the face, lips, or throat, or a sudden itchy rash
- A sudden, unusually severe headache or changes in your vision
Medicines Containing this Salt
View AllDrug Warnings
- Take It at the Same Time Every Day: Use a reminder, such as a phone alarm or calendar, to help you take Cyproterone+ethinylestradiol+folic Acid consistently.
- Inform Healthcare Providers: Tell your doctor, dentist, or surgeon that you are taking Cyproterone+ethinylestradiol+folic Acid, especially before surgery or if prolonged immobilisation is expected.
- Watch for Signs of Blood Clots: Seek immediate medical attention if you develop symptoms such as unexplained leg pain or swelling, chest pain, sudden shortness of breath, or coughing up blood.
- Follow Missed-Dose Instructions: If you vomit or have severe diarrhoea within 3 to 4 hours of taking your tablet, follow the missed-dose instructions in the patient information leaflet and use additional contraception if recommended.
- Attend Regular Check-Ups: Keep all scheduled follow-up appointments so your doctor can monitor your blood pressure, treatment response, and overall health.
Drug Interactions
- Antiseizure medicines (like phenytoin, carbamazepine): These can speed up how your liver processes Cyproterone+ethinylestradiol+folic Acid, making it less effective.
- Certain antibiotics (like rifampicin): May lower the levels of active hormones in your body, reducing the treatment's success.
- Herbal remedies (like St. John's Wort): Can significantly decrease the effectiveness of this medication.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeDo not consume alcohol while using Cyproterone+ethinylestradiol+folic Acid as it may increase the risk of side-effects and worsen the condition.
Pregnancy
unsafeCyproterone+ethinylestradiol+folic Acid is not recommended for use in pregnant women. It also acts as a contraceptive, so you should not take any other hormonal contraceptives. However, you should use reliable contraception such as condoms if necessary,
Breast Feeding
cautionCyproterone+ethinylestradiol+folic Acid should be used with caution in breastfeeding mothers as it may cause harmful effects to the nursing baby.
Driving
safe if prescribedCyproterone+ethinylestradiol+folic Acid may not affect your ability to drive.
Liver
cautionCyproterone+ethinylestradiol+folic Acid should be used with caution in patients with liver diseases. The dose may have to be adjusted by the doctor as required.
Kidney
cautionCyproterone+ethinylestradiol+folic Acid should be used with caution in patients with kidney diseases. The dose may have to be adjusted by the doctor as required.
Children
cautionCyproterone+ethinylestradiol+folic Acid is not recommended for use in children as safety and efficacy have not been established.
Habit Forming
Diet & Lifestyle Advise
- Adopt a low-glycemic diet: Focus on whole grains, legumes, vegetables, and lean proteins. High-glycemic foods like sugary snacks and white bread can spike insulin, which may worsen acne and hormonal symptoms.
- Do not smoke: Smoking significantly increases the risk of blood clots when taking oestrogen-containing medications. Stopping smoking completely is one of the most important safety measures you can take.
- Practice gentle skincare: Avoid harsh scrubs or alcohol-based skin products that can irritate your skin. Use non-comedogenic (pore-friendly) moisturisers and cleansers.
- Stay well-hydrated: Drinking plenty of water supports overall skin health and helps your body flush out toxins.
Special Advise
Before prescribing Cyproterone+ethinylestradiol+folic Acid, the doctor may perform a breast examination if you have any problems with the breast such as pain or tenderness and lumps in the breast, or if you have any other concerns. Your doctor may also perform an examination to excludes the chances of you being pregnant.
It is not advised to take any other hormonal contraceptives along with Cyproterone+ethinylestradiol+folic Acid as this medicine also serves as a contraceptive. However, ask your doctor if there is a need to take additional contraception such as condoms while using this medicine.
You may need regular check-ups while using Cyproterone+ethinylestradiol+folic Acid. You may also undergo regular cervical smear tests.
Before undergoing any blood tests or surgery, inform your doctor that you are taking Cyproterone+ethinylestradiol+folic Acid.
Do not stop taking Cyproterone+ethinylestradiol+folic Acid before completing its full course, even if you feel your symptoms are better.
Patients Concern
Disease/Condition Glossary
Polycystic ovarian syndrome: Polycystic ovary syndrome (PCOS) is a common condition, which affects the function of ovaries. It is characterized by irregular and painful periods, excess androgen in the blood (leading to excessive facial hair and acne) and polycystic ovaries (ovaries become enlarge and the egg become surrounded by fluid-filled sacs).
FAQs
Cyproterone+ethinylestradiol+folic Acid is used in the treatment of polycystic ovarian syndrome (PCOS). It is also used in the treatment of severe acne and hirsutism (excessive hair growth in the face and chest) in women.
Cyproterone+ethinylestradiol+folic Acid contains Cyproterene, Ethinylestradiol, and Folic acid. Cyproterone and Ethinyl estradiol are hormones. Cyproterone works by blocking a male hormone named androgen overproduction in the ovaries and reducing symptoms such as unwanted facial hair growth and acne. Ethinylestradiol acts as an enhancer. It enhances the effect of cyproterone by reducing the amount of androgens in the blood. It also regulates the menstrual cycle. Folic acid is a nutritional supplement.
The common side-effects of Cyproterone+ethinylestradiol+folic Acid are weight gain, nausea, tender breast, stomach pain, headache and mood changes. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Cyproterone+ethinylestradiol+folic Acid may increase the risk of blood clots. So, inform your doctor before undergoing surgery that you are taking Cyproterone+ethinylestradiol+folic Acid. Your doctor may advise you to stop taking this medicine at least 4 weeks before surgery.
Cyproterone+ethinylestradiol+folic Acid should not be used in patients with a history of breast cancer as this condition is hormonal-sensitive. Cyproterone+ethinylestradiol+folic Acid contains a hormonal combinaiton that can worsen the condition. So, it is necessary to inform your doctor before taking Cyproterone+ethinylestradiol+folic Acid that you have breast cancer.
Cyproterone+ethinylestradiol+folic Acid acts as a hormonal contraceptive, so it is not advised to take other hormonal contraceptives while taking Cyproterone+ethinylestradiol+folic Acid. However, your doctor may advise you to use reliable contraception such as condoms or other measures if necessary.
No, it is not recommended to take Cyproterone+ethinylestradiol+folic Acid during pregnancy or if you are planning for pregnancy as it may cause side effects. Consult the doctor if you have any concerns regarding its use during pregnancy.
Cyproterone+ethinylestradiol+folic Acid should be taken orally. Swallow it as a whole with a glass of water. Do not chew, crush or break it. The doctor will determine the dose based on your medical condition.
If you miss a dose of Cyproterone+ethinylestradiol+folic Acid, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose. If you are using Cyproterone+ethinylestradiol+folic Acid for contraception and miss a dose or are more than 12 hours late, use a condom during sexual intercourse for the next 2 days to prevent unwanted pregnancy.
Cyproterone+ethinylestradiol+folic Acid is a hormonal medicine which also acts as a contraceptive. However, it should be used as a contraceptive only if advised by the doctor. If you are using it for contraception, always follow the doctor’s instructions carefully.
The time taken to reduce acne varies depending on the individual and the severity of the acne condition. Typically, Cyproterone+ethinylestradiol+folic Acid may take a few weeks to a few months for noticeable improvement. Follow the doctor’s instructions for the best results.
No, you should not take Cyproterone+ethinylestradiol+folic Acid if you are planning to become pregnant. This medication regulates hormones and acts as a contraceptive, which is not suitable during pregnancy planning. Talk to your doctor for guidance on transitioning off this medicine.
When taken correctly, this medicine also helps prevent pregnancy. However, it is prescribed primarily to treat hormone-related conditions such as acne or excessive hair growth, rather than as a routine contraceptive. Follow your doctor's instructions and ask whether additional contraception is needed when starting treatment.
Mild spotting or breakthrough bleeding is common during the first few months of taking Cyproterone+ethinylestradiol+folic Acid as your body adjusts. If the bleeding is heavy, painful, or continues after your third cycle, talk to your doctor or pharmacist.
It is strongly advised that you do not smoke while taking Cyproterone+ethinylestradiol+folic Acid. Smoking significantly increases your risk of serious cardiovascular side effects, including dangerous blood clots, heart attacks, and strokes. Talk to your doctor if you need help quitting.
Some women may experience minor weight fluctuations or fluid retention when they first start taking Cyproterone+ethinylestradiol+folic Acid. This is typically temporary and mild. If you experience sudden or significant weight gain, talk to your doctor or pharmacist.
If you vomit or have severe diarrhoea within 3 to 4 hours of taking your tablet, your body may not have fully absorbed the active ingredients. Treat this as a missed dose and follow the missed-pill instructions. Talk to your doctor or pharmacist if you are unsure.
Yes, you can generally take Cyproterone+ethinylestradiol+folic Acid with common painkillers like paracetamol or ibuprofen for occasional headaches or pain. However, always check with your doctor or pharmacist before starting any new medication to rule out specific interactions.

