Brolucizumab

Brolucizumab is a prescription eye injection used to treat serious retinal conditions that can impair your sight, such as wet age-related macular degeneration (wet AMD) and diabetic macular oedema. It works by targeting abnormal blood vessel growth in the back of the eye, which helps prevent fluid leakage and swelling that damages your vision. By addressing these underlying vascular issues, this medicine aims to stabilise and protect your eyesight.

This medication is not a daily treatment; instead, it is injected directly into the eye by a trained eye specialist at regular intervals, typically every few weeks or months. Because it is given as a local injection into the eye, it does not need to be taken with food, but making positive lifestyle changes can help support your results. Eating a nutrient-rich diet with leafy greens, protecting your eyes from sunlight, and managing your blood pressure are highly recommended during your treatment course.

While Brolucizumab is highly targeted, some patients may experience mild, temporary side effects such as temporarily blurred vision, seeing small spots or floaters, or mild eye pain after the injection. However, you must contact your doctor immediately if you experience severe eye pain, worsening redness, sudden vision loss, or extreme sensitivity to light, as these can be signs of serious complications. Always consult your healthcare provider if you notice any unusual changes in your eyes between appointments.

Talk to your doctor before starting this treatment if you have a history of glaucoma, previous eye infections, or inner-eye inflammation. Do not take this if you currently have an active infection in or around your eye, or if you have active inflammation inside your eye. Your specialist will perform a thorough eye examination to ensure it is safe for you to receive the injection.

It is important to inform your doctor about all other medications you use, including prescription eye drops, over-the-counter treatments, and supplements. If you are pregnant, breastfeeding, or planning a pregnancy, talk to your doctor or pharmacist to discuss the potential risks, as this medicine should only be used in these situations if clearly necessary. Elderly individuals should also have their eye pressure monitored regularly during treatment.

Brolucizumab helps treat vision-threatening retinal conditions by reducing abnormal fluid leakage and protecting the retina from further damage. With regular use as prescribed, it helps preserve vision, improve visual function, and support long-term eye health.

• Helps Preserve and Improve Vision: By targeting the underlying cause of retinal fluid leakage, this medicine helps reduce swelling in the retina, slows vision loss, and may improve visual sharpness, making everyday activities such as reading, driving, and recognising faces easier.
• Protects Long-Term Eye Health: Regular treatment helps prevent further damage to the retina, supporting better long-term visual outcomes and helping maintain independence in daily life.
• Provides Long-Lasting Disease Control: As the condition stabilises, many patients may be able to extend the interval between injections under their ophthalmologist's guidance, reducing the frequency of clinic visits while maintaining effective protection of their vision.

• Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
• Brolucizumab should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.
• Do not self-administer.

Common Side Effects (Usually mild):

• Temporarily blurred vision
• Seeing 'floaters' (small spots, webs, or lines moving across your vision)
• Bloodspots on the white of the eye (conjunctival haemorrhage)
• Mild eye discomfort or irritation after the injection

Serious Side Effects (Consult a doctor right away):

• Sudden or severe decrease in your vision
• Severe eye pain, swelling, or worsening redness
• Extreme sensitivity to light (photophobia)
• Signs of a serious eye infection, such as yellow discharge or pus coming from the eye