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Beractant

About Beractant

Beractant is a specialised sterile medicine used to treat and prevent Respiratory Distress Syndrome (RDS) in premature infants. It helps keep the baby's tiny air sacs in the lungs open, making it much easier for them to breathe and absorb oxygen. This treatment is highly critical for newborns whose lungs have not yet fully developed.

This medicine is given in a hospital setting, usually immediately after birth or as soon as signs of breathing distress appear. Because it is given directly into the lungs by specialised healthcare professionals, there is no set home schedule or dietary adjustment required. Instead, the medical team closely manages the baby's surrounding environment and overall supportive care in the intensive care unit.

Some infants may experience temporary side effects during the procedure, such as a brief slow heart rate or short drops in oxygen levels. The healthcare team continuously monitors the baby during the process to manage these effects immediately. If you notice any unusual signs after the procedure, talk to your doctor or pharmacist.

Do not give this if the baby has certain severe congenital physical abnormalities of the airway that make placing a breathing tube impossible. The medical team will carefully evaluate the newborn's physical health before deciding to proceed with this therapy.

Because this medicine works locally inside the lungs, it does not typically interact with oral medicines or general systemic treatments. However, the medical team will coordinate it carefully with any other breathing therapies or oxygen support the baby receives.

Beractant is one of several surfactant medicines available for treating Respiratory Distress Syndrome. Depending on your baby's condition, the hospital's treatment protocol, and medicine availability, the neonatologist may choose another surfactant, such as poractant alfa or calfactant, if appropriate.

If the baby's breathing does not improve as expected, the medical team will reassess the lungs and overall condition. They may provide another dose of Beractant if appropriate, adjust breathing support, or investigate other possible causes of breathing difficulty.

Uses of Beractant

Beractant is used in the treatment of Respiratory distress syndrome (RDS). The detailed uses of Beractant are as follows: • Prevention of Respiratory Distress Syndrome (RDS): Beractant is administered to premature infants at high risk of developing RDS. It acts as a pulmonary surfactant, helping the lungs stay expanded and improving oxygen exchange by reducing surface tension in the alveoli. • Treatment of established RDS (“rescue” therapy): Beractant is also used in newborns who have already developed RDS. It helps stabilize breathing and reduces the need for mechanical ventilation by enhancing lung compliance and gas exchange.

Medicinal Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Supports Easier Breathing: Beractant brings rapid relief to premature babies struggling to breathe by restoring normal lung function. By lining the inside of the air sacs, it reduces the physical effort the baby must make to draw in air, helping them rest and recover.
  • Improves Oxygen Levels: Another major benefit is that it significantly improves oxygen levels in the blood. This helps protect vital organs from oxygen deprivation and often reduces the amount of time the newborn needs to stay on highly invasive breathing machines. Most premature babies show noticeable improvement in breathing and oxygen levels within a few hours after treatment. Early surfactant therapy has been shown to improve survival and reduce the need for prolonged mechanical ventilation in many premature infants with Respiratory Distress Syndrome. 

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Beractant is given by the trained healthcare professional.
  • Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Beractant

Common Side Effects (Usually mild):

  • Temporary slow heart rate during administration
  • Brief drop in blood oxygen levels
  • The medicine backing up into the breathing tube
  • Pale skin or temporary colour changes during the procedure
     

Serious Side Effects (Consult your doctor right away):

  • Bleeding inside the lungs (pulmonary hemorrhage)
  • Complete blockage of the breathing tube
  • Severe, sudden drops in blood pressure

Medicines Containing this Salt

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Drug Warnings

  • Inspect Before Use: The liquid must be visually inspected before use; it should be off-white to light brown and may have some visible settling.
  • Swirl, Don't Shake: Gently swirl the vial to mix the medicine; do not shake it, as shaking can cause excessive foaming.
  • Continuous Baby Monitoring: Continuous monitoring of the baby’s heart rate, colour, and oxygen saturation is mandatory during and immediately after giving the medicine.
  • Hospital Use Only: Only qualified hospital staff trained in neonatal resuscitation should handle and give this medicine.

Drug Interactions

  • Active lung bleeding: Must be used with extreme caution if the infant is experiencing bleeding in the lungs, as the medicine could worsen airway obstruction.
  • Severe congenital heart anomalies: Rapid changes in lung pressure after giving this medicine can affect blood flow through the heart, requiring careful monitoring.
     

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    not applicable

    It is intended for Pediatrics.

  • Safety Warning

    Pregnancy

    not applicable

    It is intended for Pediatrics.

  • Safety Warning

    Breast Feeding

    not applicable

    It is intended for Pediatrics.

  • Safety Warning

    Driving

    not applicable

    It is intended for Pediatrics.

  • Safety Warning

    Liver

    consult your doctor

    If your child has liver problems, the doctor will weigh the benefits and potential risks before prescribing Beractant.

  • Safety Warning

    Kidney

    consult your doctor

    If your child has kidney disease, the doctor will weigh the benefits and potential risks before prescribing Beractant.

  • Safety Warning

    Children

    safe if prescribed

    Based on your child's condition, your doctor will decide the suitable dose of this medicine.

Habit Forming

No

Diet & Lifestyle Advise

  • Breast Milk Support: Provide maternal breast milk if possible, as it delivers essential nutrients and immune support to help the recovering premature baby heal.
  • Calm Healing Environment: Keep the baby's environment in the intensive care unit quiet and low-stimulation to minimise stress and promote deep sleep.
  • Strict Hand Hygiene: Adhere strictly to hospital hand hygiene and visitation rules to protect the baby's vulnerable immune system from infections.

Patients Concern

Disease/Condition Glossary

Respiratory distress syndrome (RDS): RDS is mainly caused when the baby's lungs do not have enough surfactant. The earlier the infant is born, the more probable they may have RDS. Under such conditions, the baby requires extra oxygen, which is done through ventilatory support.

FAQs

Beractant is used to treat Respiratory distress syndrome (RDS).

Beractant contains Beractant, a natural surfactant that acts similarly to your baby’s surfactant, helping your baby breathe normally. It will help your baby breathe normally until it produces its own surfactant.

No, it is not necessary to use Beractant in all premature babies. It should be used only in premature infants suffering from or at risk of a condition called respiratory distress syndrome (RDS).

Beractant can be used in those whose pregnancy lasted less than 32 weeks, whose infants are in danger of developing RDS and require a tube put into the windpipe for stabilisation, or who have indications of surfactant deficiency.

It is given as a liquid directly into the baby's windpipe through a breathing tube by a trained neonatal specialist in the hospital. Talk to your doctor if you want to know more about the procedure.

No, this medicine is strictly for hospital use in neonatal intensive care units and cannot be used or stored at home. Talk to your doctor or pharmacist if you have questions.

Premature babies often lack a natural fluid that keeps their lungs open, making breathing extremely difficult. This medicine replaces that fluid so they can breathe. Talk to your doctor for more details.

Yes, if the baby still has trouble breathing, the medical team may give additional doses within the first 48 hours of life. Talk to your doctor about the treatment plan.

It is made from highly purified natural extracts from animal lungs that match the biological activity of human lung fluids. Talk to your doctor or pharmacist if you want more details.

Most side effects are temporary and happen only during administration. It is generally well-tolerated and helps prevent long-term lung damage from breathing machines. Talk to your doctor if you have concerns.

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