Silodosin+tadalafil
About Silodosin+tadalafil
Silodosin+tadalafil is used to treat the symptoms of benign prostatic hyperplasia. Benign prostatic hyperplasia is a common condition in which the cells of the prostate gland begin to multiply. Benign prostatic hyperplasia mostly occurs in older men.
Silodosin+tadalafil consists of Silodosin and Tadalafil. Silodosin helps relax the muscles of the prostate and the bladder's opening. Tadalafil works by relaxing the muscles in the prostate and bladder.
Silodosin+tadalafil may cause common side effects such as headaches, dizziness, nausea, facial flushing, indigestion, stuffy nose, muscle aches, diarrhoea, stomach pain and dry mouth. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
Do not take Silodosin+tadalafil if you are allergic to Silodosin+tadalafil or any of its components. Silodosin+tadalafil is intended for use in men only; women should not take Silodosin+tadalafil, especially during pregnancy or while breastfeeding. Silodosin+tadalafil should not be given to children as safety and efficacy have not been established.
Medicinal Benefits
- Silodosin+tadalafil is a combination of Alfuzosin and Tadalafil.
- This combination of alfuzosin and tadalafil relaxes the human detrusor (a muscle that forms the bladder wall layer) and prostatic tissues.
- Silodosin+tadalafil aids in the relief of symptoms of benign prostatic hyperplasia and makes it simpler to pass urine.
Directions for Use
- Silodosin+tadalafil can be taken with or without food as advised by your doctor.
- It is recommended to take Silodosin+tadalafil once daily or as advised by your doctor.
- Swallow Silodosin+tadalafil as a whole with a full glass of water.
- Do not chew, crush, or break it.
Side Effects of Silodosin+tadalafil
- Headaches
- Nausea
- Facial flushing and hot flushes
- Indigestion
- Stuffy nose
- Muscle aches
- Dizziness
- Vomiting
- Diarrhoea
- Stomach pain
- Dry mouth
Drug Warnings
- Do not take Silodosin+tadalafil if you are allergic to Silodosin+tadalafil or any other components present in it.
- Try not to stop taking it on your own.
- If you take Silodosin+tadalafil with any antihypertensive medicine, your blood pressure could suddenly drop to a life-threatening level. So, avoid intake of Silodosin+tadalafil with antihypertensive drugs.
- Inform your doctor if you have/had a heart attack or stroke or heart failure, low blood pressure, kidney or liver disease, have certain eye diseases, or loss of vision due to loss of blood flow to the optic (eye) nerve before taking Silodosin+tadalafil.
- You are advised not to drive or operate heavy machinery after taking Silodosin+tadalafil, as it may cause dizziness.
- Avoid consuming alcohol along with Silodosin+tadalafil, as it could lead to increased dizziness and drowsiness.
- Older patients may be more sensitive to the side effects of Silodosin+tadalafil, especially dizziness and low blood pressure when getting up from a sitting or lying position.
- Silodosin+tadalafil is intended for male patients only. Therefore, it should not be administered to women and children under 18 years of age.
Drug Interactions
Drug-Drug Interactions: Silodosin+tadalafil may interact with antibiotics (e.g. erythromycin, clarithromycin), antiretroviral medications (e.g. delavirdine, atazanavir), antifungal medications (e.g. itraconazole, ketoconazole), anticancer medication (e.g. ceritinib), alpha-blockers (tamsulosin), anti-anginal (nitroglycerin) and medicines used to treat pulmonary hypertension (e.g. riociguat).
Drug-Food Interactions: Limit or avoid the intake of alcohol and nicotine.
Drug-Disease Interactions: Silodosin+tadalafil may interact with disease conditions like glaucoma, cardiovascular disease, renal dysfunction, hepatic dysfunction, and pulmonary disease.
Drug-Drug Interactions Checker List:
Safety Advice

Alcohol
unsafeIt is advised to limit or quit the consumption of alcohol.

Pregnancy
not applicableIt is intended for men.

Breast Feeding
not applicableIt is intended for men.

Driving
cautionSilodosin+tadalafil causes dizziness, so drive only if you are alert.

Liver
cautionExtreme caution should be exercised while using Silodosin+tadalafil in patients with liver disease. So, inform your doctor before receiving Silodosin+tadalafil if you have a history of liver disease or condition. Your doctor will prescribe only if the benefits outweigh the risks.

Kidney
cautionExtreme caution should be exercised while using Silodosin+tadalafil in patients with kidney disease. So, inform your doctor before receiving Silodosin+tadalafil if you have a history of kidney disease or condition. Your doctor will prescribe only if the benefits outweigh the risks

Children
unsafeSafety and effectiveness of Silodosin+tadalafil have not been established in patients below 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Simple lifestyle adjustments can help relieve symptoms of an enlarged prostate gland and erectile dysfunction.
- Eat a nutritious diet and exercise every day. Reduce your tension and worry.
- Limit your intake of alcohol, caffeine, and artificial sweeteners, as these might irritate the bladder and aggravate urine symptoms.
- Nicotine intake should be discontinued. It can irritate the bladder and aggravate urinary problems.
- Reduce your drinking and avoid drinking anything for 2 hours before night.
- Consult your doctor to determine whether your medications, such as antidepressants or decongestants, are worsening your urinary problems.
- Consume more fruits and vegetables. This can help you avoid constipation. Constipation can strain the bladder, exacerbating your symptoms.
Patients Concern
Disease/Condition Glossary
Benign prostatic hyperplasia (BPH): Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland due to the multiplication of cells. This leads to swelling and compression of the urethra, limiting urine flow. It is an age-associated prostate gland enlargement which can cause problems with urination. BPH symptoms include loss of bladder control, frequent urination, inability to urinate, incomplete bladder emptying, weak urinary stream, dribbling at the end of the urinary stream, sudden urge to urinate, and painful urination.
FAQs
Silodosin+tadalafil is used to treat benign prostatic hyperplasia (enlarged prostate). It is also used in the treatment of erectile dysfunction.
The combination of silodosin and tadalafil exerts an additive relaxant effect on the human detrusor (a muscle that forms a layer of the bladder wall) and prostatic tissues. This may help increase urine flow or reduce symptoms.
No, it is a medication recommended by a doctor to treat or prevent specific medical issues. Taking it on your own can lead to adverse side effects.
Silodosin+tadalafil is safe when taken at the dose and for the duration your doctor prescribes. Take it exactly as directed, and do not miss any doses. Follow your doctor's instructions carefully and notify your doctor if any adverse effects bother you.

