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Polygeline+calcium Chloride+potassium Chloride+sodium Chloride

About Polygeline+calcium Chloride+potassium Chloride+sodium Chloride

Polygeline+calcium Chloride+potassium Chloride+sodium Chloride belongs to a group of medications called “plasma substitutes.” It restores plasma volume to treat hypovolaemic shock (severe blood/fluid loss causing a sudden drop in blood pressure) caused by bleeding, inflammation, burns, or severe trauma. Additionally, it is used to replace fluids during plasma exchange, support circulation during heart surgery (extra-corporeal circulation), perfuse organs during transplantation, and mix with insulin for injections.

Polygeline+calcium Chloride+potassium Chloride+sodium Chloride contains the active ingredient Polygeline, along with essential electrolytes, namely calcium chloride, potassium chloride, and sodium chloride. Polygeline is composed of large gelatin molecules that increase pressure in the blood vessels and help draw fluid from the surrounding tissues back into the blood vessels. This action helps increase the circulating blood volume, thereby keeping blood pressure stable and improving blood flow to tissues and organs. Calcium chloride, potassium chloride, and sodium chloride work by quickly restoring lost fluids and minerals in the body.

A trained healthcare professional will administer Polygeline+calcium Chloride+potassium Chloride+sodium Chloride in a medical setting. Your doctor will determine the dosage and duration of this medication based on your medical condition. In some cases, it may cause side effects like nausea, vomiting, dizziness, skin rash, fever, chills, shortness of breath, and irregular heartbeats. Most of these side effects will resolve gradually over time without requiring medical attention. However, if these side effects persist or worsen, please consult your doctor.

Before starting treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride, inform your doctor if you are allergic to any of its ingredients. Consult your doctor for advice before receiving Polygeline+calcium Chloride+potassium Chloride+sodium Chloride if you are pregnant, planning to become pregnant, or breastfeeding. Additionally, inform your doctor of any health conditions, such as oedema (swelling due to fluid buildup in the body), inherited bleeding disorder (such as haemorrhagic diathesis), varices (enlarged veins), difficulty breathing, or heart or kidney problems before starting treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride.

Uses of Polygeline+calcium Chloride+potassium Chloride+sodium Chloride

Polygeline+calcium Chloride+potassium Chloride+sodium Chloride is used in the treatment of hypovolaemic shock. The detailed uses of Polygeline+calcium Chloride+potassium Chloride+sodium Chloride are as follows: • Treatment of hypovolaemic shock: Polygeline+calcium Chloride+potassium Chloride+sodium Chloride is primarily used as a plasma substitute to restore blood volume in cases of hypovolaemic shock (severe blood/fluid loss causing a sudden drop in blood pressure). • Increases blood volume: Polygeline+calcium Chloride+potassium Chloride+sodium Chloride helps increase blood volume by drawing fluid from surrounding tissues into blood vessels. • Supports organ function: It Restore lost electrolytes and fluids, supporting circulation and organ function.

Medicinal Benefits

Polygeline+calcium Chloride+potassium Chloride+sodium Chloride is a plasma substitute medication primarily used to treat hypovolaemic shock (severe blood/fluid loss causing a sudden drop in blood pressure) caused by bleeding, inflammation, burns, or severe trauma. Additionally, it is used to replace fluids during plasma exchange, support circulation during heart surgery (extra-corporeal circulation), perfuse organs during transplantation, and mix with insulin for injections. It contains the active ingredient Polygeline, which helps increase the circulating blood volume, thereby keeping blood pressure stable and improving blood flow to tissues and organs. It also contains essential electrolytes, namely calcium chloride, potassium chloride, and sodium chloride, which help quickly restore lost fluids and minerals in the body.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Polygeline+calcium Chloride+potassium Chloride+sodium Chloride will be administered by a healthcare professional in a medical setting.
  • Do not self-administer it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Polygeline+calcium Chloride+potassium Chloride+sodium Chloride

  • Nausea
  • Vomiting
  • Dizziness
  • Fever and chills
  • Urticarial skin rash (wheals)
  • Dyspnoea (shortness of breath)
  • Tachycardia (fast heartbeat)
  • Bradycardia (slow heartbeat)
  • Hypotension (low blood pressure)
  • Hypercalcaemia (increased calcium levels in the blood)

Drug Warnings

Before undergoing treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride, inform your doctor if you are allergic to any of its ingredients. Also, inform your doctor if you are taking any prescription or non-prescription medications, vitamins, and herbal supplements before using Polygeline+calcium Chloride+potassium Chloride+sodium Chloride, to rule out any side effects or interactions. Consult your doctor for advice before receiving Polygeline+calcium Chloride+potassium Chloride+sodium Chloride if you are pregnant, planning to become pregnant, or breastfeeding. Polygeline+calcium Chloride+potassium Chloride+sodium Chloride should be used with caution and under medical supervision in patients with hypertension (high blood pressure), congestive heart failure, pulmonary oedema (excess fluid buildup in the lungs), anuria (no urine production), oesophageal varices (enlarged veins in oesophagus), or those who have taken histamine medications within the last 7 days. Additionally, inform your doctor before starting treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride if you have any health conditions, such as oedema (swelling due to fluid buildup in the body), inherited bleeding disorder (such as haemorrhagic diathesis), varices (enlarged veins), difficulty breathing, or heart or kidney problems.

Drug Interactions

Drug-Drug Interactions: Polygeline+calcium Chloride+potassium Chloride+sodium Chloride may interact with medications used to treat heart failure (digoxin, digitoxin) and hypotension (trimetaphan camsylate).

Drug-Food Interactions: No interactions were found/established.

Drug-Disease Interactions: Inform your doctor before starting treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride if you have certain health conditions, such as oedema (swelling due to fluid buildup in the body), inherited bleeding disorder (such as haemorrhagic diathesis), varices (enlarged veins), difficulty breathing, or heart or kidney problems.

Drug-Drug Interactions Checker List:

  • DIGOXIN
  • DIGITOXIN
  • TRIMETAPHAN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is unknown if alcohol interacts with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride. Please consult your doctor for advice.

    • Safety Warning

      Pregnancy

      safe if prescribed

      If plasma volume replacement is needed during pregnancy, Polygeline+calcium Chloride+potassium Chloride+sodium Chloride may be used as an alternative when blood is unavailable. If you are pregnant or planning to become pregnant, please consult your doctor for advice before using Polygeline+calcium Chloride+potassium Chloride+sodium Chloride.

    • Safety Warning

      Breast Feeding

      consult your doctor

      If you are breastfeeding, please consult your doctor for advice before using Polygeline+calcium Chloride+potassium Chloride+sodium Chloride.

    • Safety Warning

      Liver

      consult your doctor

      Please inform your doctor before undergoing treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride if you have liver problems.

    • Safety Warning

      Kidney

      consult your doctor

      Please inform your doctor before undergoing treatment with Polygeline+calcium Chloride+potassium Chloride+sodium Chloride if you have kidney problems.

    • Safety Warning

      Children

      consult your doctor

      Please consult your doctor if you have concerns regarding the usage of Polygeline+calcium Chloride+potassium Chloride+sodium Chloride in children below 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Drink plenty of fluids, such as water, broths, and oral rehydration solutions, to restore and maintain fluid balance in the body.
    • Eat a nutrient-dense diet with vegetables, whole grains, fruits, proteins, and healthy fats to repair injured tissue and overall recovery.
    • Hypovolaemic shock may be linked to bleeding, so consume iron-rich foods, such as lean meat and spinach, to support red blood cell production.
    • Increase your sodium intake under medical supervision to help maintain blood volume.
    • Engage in light exercise gradually to improve your blood circulation and heart health, under medical supervision.

    Special Advise

    • Regular monitoring of blood cell counts and electrolyte levels is advised.

    Patients Concern

    Disease/Condition Glossary

    Hypovolaemic shock: It is a critical, life-threatening condition that occurs when the body suddenly loses a significant amount of blood or fluids. This causes a drop in the blood volume, reducing the amount of blood circulating throughout the body. The most common causes are severe bleeding from injuries, serious cuts, or gastrointestinal ulcers. Other causes include burns, a tear in the large blood vessels or heart, excessive vomiting or diarrhea, organ inflammation, heavy bleeding during pregnancy, and extreme sweating. Symptoms include a fast heartbeat, shallow breathing, weakness, fatigue, confusion, dizziness, no or low urine output, low blood pressure (hypotension), and cold and sweaty skin.

    FAQs

    Polygeline+calcium Chloride+potassium Chloride+sodium Chloride is a plasma substitute medication used to treat hypovolaemic shock (severe blood/fluid loss causing a sudden drop in blood pressure). Additionally, it is used to replace fluids during plasma exchange, support circulation during heart surgery (extra-corporeal circulation), perfuse organs during transplantation, and mix with insulin for injections.

    Polygeline+calcium Chloride+potassium Chloride+sodium Chloride contains the active ingredient Polygeline, along with essential electrolytes, namely calcium chloride, potassium chloride, and sodium chloride. Polygeline is composed of large gelatin molecules that increase pressure in the blood vessels and help draw fluid from the surrounding tissues back into the blood vessels. This action helps increase the circulating blood volume, thereby keeping blood pressure stable and improving blood flow to tissues and organs. Calcium chloride, potassium chloride, and sodium chloride work by quickly restoring lost fluids and minerals in the body.

    Yes, Polygeline+calcium Chloride+potassium Chloride+sodium Chloride may cause common side effects such as nausea, vomiting, dizziness, skin rash, fever, chills, shortness of breath, and irregular heartbeats in some individuals. Most of these side effects will resolve gradually over time without requiring medical attention. However, if these side effects persist or worsen, please consult your doctor.

    Polygeline+calcium Chloride+potassium Chloride+sodium Chloride may increase the risk of hypercalcaemia (high calcium levels in the blood). Therefore, Polygeline+calcium Chloride+potassium Chloride+sodium Chloride should be avoided in patients with or at risk for hypercalcaemia.

    Polygeline+calcium Chloride+potassium Chloride+sodium Chloride may pose a significant risk if used in conditions with too much fluid in the blood or tissues, such as hypertension (high blood pressure), congestive heart failure, pulmonary oedema (excess fluid buildup in the lungs), anuria (no urine production), oesophageal varices (enlarged veins in oesophagus), or in patients who have taken histamine medications within the last 7 days. Therefore, Polygeline+calcium Chloride+potassium Chloride+sodium Chloride should be used with caution and under medical supervision if you have these health conditions.

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    Polygeline+calcium Chloride+potassium Chloride+sodium Chloride

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