Voglibose+metformin+pioglitazone
About Voglibose+metformin+pioglitazone
Metformin+pioglitazone+voglibose is used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).
Metformin+pioglitazone+voglibose contains Voglibose, Metformin, and Pioglitazone. Voglibose works by inhibiting the intestinal enzymes responsible for breaking complex sugars into simple sugars like glucose. This process prevents the rise of blood glucose levels. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood. Pioglitazone improves the sensitivity of liver, muscle, and fat cells to insulin. It allows cells to remove glucose from blood more effectively. Thereby, Metformin+pioglitazone+voglibose helps to control blood sugar levels.
Take Metformin+pioglitazone+voglibose as prescribed by your doctor. You are advised to take Metformin+pioglitazone+voglibose for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Most of these side effects of Metformin+pioglitazone+voglibose do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Metformin+pioglitazone+voglibose should not be taken if you are allergic to any component present in it or if you have lactic acidosis (lactic acid build up in the bloodstream), cardiovascular risk, CHF (Congestive heart failure), and type I diabetes. During pregnancy/lactation, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Keep your doctor informed about your health condition and all the medicines you take before taking Metformin+pioglitazone+voglibose to rule out any side effects/interactions. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness. Metformin+pioglitazone+voglibose is not recommended in children below 18 years of age.
Uses of Voglibose+metformin+pioglitazone
Medicinal Benefits
Metformin+pioglitazone+voglibose contains three antidiabetic drugs (Voglibose, Metformin and Pioglitazone) used in the treatment of type 2 diabetes. Voglibose works by inhibiting the intestinal enzymes responsible for breaking complex sugars into simple sugars like glucose. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Also, it decreases the amount of glucose produced by the liver and preserves the functioning of beta cells in the pancreas that produce insulin. Thereby, Metformin+pioglitazone+voglibose helps to control blood sugar levels.
Directions for Use
- Take Metformin+pioglitazone+voglibose with or without food or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Voglibose+metformin+pioglitazone
- Stomach pain
- Nausea
- Diarrhoea
- Vomiting
- Headache
- Dizziness
- Metallic taste or Changes in taste
- Low blood sugar
- Skin rash
- Bloating
- Flatulence (intestinal wind/gas)
Drug Warnings
Inform your doctor if you are allergic to any foods or medicines. Metformin+pioglitazone+voglibose is not recommended for children. Do not use Metformin+pioglitazone+voglibose unless instructed by the doctor if you are a pregnant woman or nursing mother. Metformin+pioglitazone+voglibose should be used with caution in elderly patients. Avoid alcohol consumption with Metformin+pioglitazone+voglibose as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Metformin+pioglitazone+voglibose. Take short, frequent meals and avoid prolonged fasting while taking Metformin+pioglitazone+voglibose. Metformin+pioglitazone+voglibose should not be stopped without consulting your doctor, even if you feel better. If you stop taking Metformin+pioglitazone+voglibose abruptly, your blood sugar levels may rise, increasing your risk of vision loss (retinopathy), kidney damage (nephropathy), and nerve damage (neuropathy).
Drug Interactions
Drug-Drug Interactions: Metformin+pioglitazone+voglibose is shown to interact with various drugs. Some of them include; antidiabetic drugs (e.g. pioglitazone), antiplatelet medicine (e.g. clopidogrel), antibiotics (e.g. gatifloxacin), and antirheumatic drugs (e.g. leflunomide).
Drug-Food Interactions: Metformin+pioglitazone+voglibose may interact with alcohol. Therefore, avoid the consumption of alcohol with Metformin+pioglitazone+voglibose as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Drug-Disease Interactions: If you have lactic acidosis, renal dysfunction, liver disease, congestive heart failure, dehydration, shock, myocardial infarction, asphyxia (a condition arising when the body is deprived of oxygen), diarrhoea, vomiting, anaemia, alcoholism, cardiovascular risk, CHF (congestive heart failure), and type I diabetes, inform your doctor before taking Metformin+pioglitazone+voglibose.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid consumption of alcohol with Metformin+pioglitazone+voglibose as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Pregnancy
cautionThe safety of Metformin+pioglitazone+voglibose in pregnancy has not been established. Do not use Metformin+pioglitazone+voglibose unless prescribed by the doctor.
Breast Feeding
cautionThe safety of Metformin+pioglitazone+voglibose in nursing has not been established.; your doctor will decide whether breastfeeding mothers can take Metformin+pioglitazone+voglibose or not.
Driving
cautionYour driving ability may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience dizziness or drowsiness.
Liver
cautionInform your doctor before receiving Metformin+pioglitazone+voglibose if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionInform your doctor before receiving Metformin+pioglitazone+voglibose if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
unsafeMetformin+pioglitazone+voglibose is not recommended for children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Every week, devote at least 150 minutes to moderate-intensity physical activity or one hour and 15 minutes to high-intensity exercise.
- Losing weight gradually to achieve a healthy BMI (18.5 to 24.9).
- Replace refined carbohydrates with whole grain foods and increase intake of fruits and vegetables and other fibre-rich foods.
- Reduce your consumption of saturated fat (or hidden fats) in foods such as chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-rich oils for everyday cooking.
- Avoid excessive stress because it can raise your blood sugar level. You can control stress-related blood sugar changes using stress management techniques such as mindfulness, meditation, or yoga.
- Choose low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
- Maintaining a normal blood pressure (120/80) as much as possible reduces the risk of cardiovascular disease in people with diabetes.
Special Advise
- Regular blood tests are recommended while taking Metformin+pioglitazone+voglibose to monitor blood sugar levels.
Patients Concern
Disease/Condition Glossary
Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, weight gain may occur, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and increased chance of heart attack or stroke.
FAQs
Metformin+pioglitazone+voglibose belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
Metformin+pioglitazone+voglibose contains Voglibose, Metformin and Pioglitazone. Voglibose works by inhibiting the intestinal enzymes responsible for breaking complex sugars into simple sugars like glucose. This process prevents the rise of blood glucose levels. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Metformin+pioglitazone+voglibose helps to control blood sugar levels.
Metformin+pioglitazone+voglibose may increase the risk of low blood sugar levels, especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure, such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
You are not recommended to stop taking Metformin+pioglitazone+voglibose on your own as discontinuing Metformin+pioglitazone+voglibose suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Metformin+pioglitazone+voglibose, please consult your doctor so that alternative medicine may be prescribed.
