Mavacamten
About Mavacamten
Mavacamten is used to treat obstructive hypertrophic cardiomyopathy, a condition in which the heart muscle thickens, making it harder for blood to flow. It helps relieve symptoms such as shortness of breath, chest pain, and tiredness.
Mavacamten works by helping the heart muscle relax, improving blood flow and reducing strain on the heart. This helps the heart pump more effectively and improves overall heart function.
Take Mavacamten exactly as prescribed by your doctor. Swallow it whole with a glass of water; do not crush or chew it. In some cases, Mavacamten may cause side effects such as dizziness, fatigue, and fainting. Please consult your doctor if the side effects persist or worsen.
If you are allergic to Mavacamten or any other medicines, please tell your doctor. Mavacamten should not be taken by pregnant women. If you are a breastfeeding mother, please consult your doctor before taking Mavacamten. Mavacamten should not be given to children.
Medicinal Benefits
- Mavacamten effectively treats obstructive hypertrophic cardiomyopathy and helps manage its symptoms in adults.
- Helps relax the thickened heart muscle.
- Improves blood flow from the heart.
- Reduces shortness of breath, chest pain, and tiredness.
- Supports better pumping efficiency of the heart.
- Reduces strain on the heart muscle.
Directions for Use
- Mavacamten can be taken with or without food, or as advised by your doctor.
- Mavacamten is usually taken once a day, or as prescribed by your doctor.
- Swallow Mavacamten as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Mavacamten
- Dizziness
- Fatigue
- Fainting
Medicines Containing this Salt
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Drug Warnings
- Do not take Mavacamten if you are allergic to it or any ingredient in Mavacamten.
- Please seek medical advice before using Mavacamten if you have/had liver, kidney, or heart problems before taking Mavacamten.
- Mavacamten is not prescribed for use in pregnant women.
- It is not known if Mavacamten passes into breast milk. Because it may affect the baby, you may need to stop breastfeeding during treatment and for 4 months after the last dose, or your doctor may advise stopping the medicine based on your situation.
- In some cases, Mavacamten may cause blurred vision, drowsiness or dizziness; if you experience these symptoms, do not drive or operate machines.
- Mavacamten is not recommended for children.
- Let your doctor know if you are taking any other medicines, including supplements and herbal products, to avoid potential side effects or interactions.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.
- Blood pressure medicine (Atenolol)
• Potential effect: May cause additive negative effects on heart function, increasing the risk of reduced heart pumping ability and heart failure. - Stomach acid–reducing medicine (Cimetidine, Esomeprazole)
• Potential effect: May increase the blood levels of Mavacamten and raise the risk of side effects. - Antibiotic medicine (Ciprofloxacin)
• Potential effect: May increase the blood levels of Mavacamten by slowing its breakdown, increasing the risk of adverse effects. - Fits medicine (Carbamazepine)
• Potential effect: May reduce the blood levels of Mavacamten by increasing its metabolism, leading to decreased effectiveness. - Heart medicine (Diltiazem, Verapamil)
• Potential effect: May increase Mavacamten levels and, when combined with other heart medicines, increase the risk of heart failure due to reduced cardiac function. - Antifungal medicines (Fluconazole, Itraconazole)
• Potential effect: May significantly increase the blood levels of Mavacamten and increase the risk of serious adverse effects such as heart failure.
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Inform your doctor if you have a history of the following conditions before taking Mavacamten, as it may worsen your condition.
- Liver problems
- Kidney problems
- Heart problems
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is unknown whether alcohol interacts with Mavacamten. However, it is advised to avoid alcohol when taking this medicine as a precaution.
Pregnancy
unsafeMavacamten is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.
Breast Feeding
cautionMavacamten is known to pass through the breast milk. So, it is recommended to consult your doctor during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk.
Driving
cautionMavacamten may cause side effects such as dizziness or fatigue. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.
Liver
cautionMavacamten should be used with caution if you have severe liver disease. Please consult your doctor if you have liver problems or any concerns regarding this.
Kidney
cautionMavacamten should be used with caution if you have severe kidney disease. Please consult your doctor if you have kidney problems or any concerns regarding this.
Children
unsafeMavacamten is not recommended for children as the safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
Diet:
- Follow a heart-healthy diet with fruits, vegetables, whole grains, and lean proteins.
- Limit salt intake to reduce strain on the heart.
- Avoid high-fat and processed foods.
Fluids:
- Drink fluids as advised by your doctor and avoid excess intake if restricted.
Physical Activity:
- Do light to moderate exercise as recommended by your doctor.
- Avoid strenuous activities that may worsen symptoms.
Habits:
- Avoid smoking and limit alcohol consumption.
- Maintain a healthy body weight.
Monitoring & Care:
- Attend regular check-ups to monitor heart function.
- Report symptoms like increased breathlessness, dizziness, or chest pain promptly.
Patients Concern
Disease/Condition Glossary
Obstructive hypertrophic cardiomyopathy: It is a condition in which the heart muscle becomes abnormally thick, especially in the walls of the left ventricle, which can block or reduce the flow of blood leaving the heart. This makes it harder for the heart to pump blood effectively and may lead to symptoms like shortness of breath, chest pain, dizziness, or fatigue.
FAQs
Mavacamten is used to treat obstructive hypertrophic cardiomyopathy, a condition in which the heart muscle thickens and obstructs blood flow.
Mavacamten works by controlling how the heart muscle contracts and relaxes. It reduces the interaction between actin and myosin (proteins that help the heart muscle contract), so the heart does not squeeze too strongly. This helps improve blood flow and relieve symptoms such as breathlessness, chest pain, and tiredness.
Mavacamten should be taken in the dose and for the duration advised by your doctor. Do not stop taking Mavacamten on your own, as this may worsen your condition and increase the risk of serious heart problems. Always consult your doctor before making any changes.
Mavacamten can cause dizziness as a side effect. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.
Mavacamten should be used with caution in people with kidney diseases. The doctor may adjust the dose based on the medical conditions of the affected person.
No, Mavacamten is not a habit-forming medicine. However, take Mavacamten as advised by the doctor. Do not exceed the prescribed dose.
Mavacamten should be used with caution in people with liver diseases. The doctor may adjust the dose based on the medical conditions of the affected person.
Do not stop taking Mavacamten without consulting your doctor, as it might cause a relapse of symptoms or make them worse. To treat your condition effectively, continue taking Mavacamten for as long as it has been prescribed. Talk to your doctor if you have any concerns.
The side effects of Mavacamten include dizziness, fatigue, and fainting. If these side effects persist or worsen, please consult your doctor.
