Lobeglitazone Sulfate+metformin Hydrochloride
About Lobeglitazone Sulfate+metformin Hydrochloride
Lobeglitazone Sulfate+metformin Hydrochloride is combination medication used to treat type 2 diabetes mellitus. Type-2 diabetes mellitus is also known as non-insulin-dependent diabetes or adult-onset diabetes. It is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
Lobeglitazone Sulfate+metformin Hydrochloride is a combination of two medicines: Lobeglitazone sulfate and Metformin hydrochloride. Lobeglitazone sulfate improves blood sugar control by making fat cells more responsive to insulin through peroxisome proliferator-activated receptor (PPAR) activation. Metformin hydrochloride acts by decreasing liver glucose production and intestinal glucose uptake. Together, Lobeglitazone Sulfate+metformin Hydrochloride helps control blood sugar levels.
Take Lobeglitazone Sulfate+metformin Hydrochloride as prescribed. You are advised to take Lobeglitazone Sulfate+metformin Hydrochloride for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Lobeglitazone Sulfate+metformin Hydrochloride may cause side effects such as hypoglycemia, weight gain, swelling, headache, stomach pain, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.
Do not take Lobeglitazone Sulfate+metformin Hydrochloride if you are allergic to any of its contents. Do not consume alcohol or fast for prolonged periods. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all the medicines you are taking and if you have any pre-existing medical conditions.
Uses of Lobeglitazone Sulfate+metformin Hydrochloride
Medicinal Benefits
Lobeglitazone Sulfate+metformin Hydrochloride is suggested for the management of type 2 diabetes to be followed with the right diet and exercise. Lobeglitazone Sulfate+metformin Hydrochloride is a combination of two medicines: Lobeglitazone sulfate and Metformin hydrochloride. Lobeglitazone sulfate improves blood sugar control by making fat cells more responsive to insulin through peroxisome proliferator-activated receptor (PPAR) activation. Metformin hydrochloride acts by decreasing liver glucose production and intestinal glucose uptake. Together, Lobeglitazone Sulfate+metformin Hydrochloride helps control blood sugar levels.
Directions for Use
- Lobeglitazone Sulfate+metformin Hydrochloride can be taken with food or as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
- Swallow Lobeglitazone Sulfate+metformin Hydrochloride as a whole with a glass of water.
- Do not break, crush or chew it.
Storage
Side Effects of Lobeglitazone Sulfate+metformin Hydrochloride
- Hypoglycemia
- Weight gain
- Swelling
- Headache
- Stomach pain
- Diarrhoea
- Vomiting
- Nausea
Drug Warnings
Do not take Lobeglitazone Sulfate+metformin Hydrochloride if you are allergic to any of its contents. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all the medicines you are taking and if you have any pre-existing medical conditions. Lobeglitazone Sulfate+metformin Hydrochloride should be used with caution in patients with heart diseases. Lobeglitazone Sulfate+metformin Hydrochloride may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing; consult your doctor immediately if you experience these symptoms. Inform your doctor if you have severe liver or kidney problems. Do not consume excess alcohol as it increases the risk of lactic acidosis.
Drug Interactions
Drug-Drug Interactions: Lobeglitazone Sulfate+metformin Hydrochloride may have an interaction with antibiotics (clarithromycin, gatifloxacin), carbonic anhydrase inhibitor (acetazolamide, methazolamide), anticonvulsant (topiramate, zonisamide), nonsteroidal anti-Inflammatory drug (NSAID) (ibuprofen, ketorolac), antipsychotic (haloperidol), antihypertensive (enalapril, captopril), diuretic (furosemide), anticoagulant (dicumarol).
Drug-Food Interactions: Intake of excess alcohol may increase the chance of a life-threatening condition known as lactic acidosis.
Drug-Disease Interactions: Inform your doctor if you have lactic acidosis, vitamin B12 deficiency, liver disease, renal dysfunction, hypoglycemia or anemia.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid drinking alcohol with Lobeglitazone Sulfate+metformin Hydrochloride as it may increase the risk of hypoglycemia and lactic acidosis.
Pregnancy
cautionPlease consult your doctor if you have any concerns regarding the use of Lobeglitazone Sulfate+metformin Hydrochloride in pregnancy; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionLobeglitazone Sulfate+metformin Hydrochloride should not be used in breastfeeding mothers as it may pass into breast milk. Consult your doctor if you have any concerns.
Driving
cautionIt is not known if Lobeglitazone Sulfate+metformin Hydrochloride affects your ability to drive. Drive or operate machinery only if you are alert after taking Lobeglitazone Sulfate+metformin Hydrochloride.
Liver
cautionLobeglitazone Sulfate+metformin Hydrochloride should be taken with caution in patients with liver diseases. Consult your doctor if you have any concerns.
Kidney
cautionLobeglitazone Sulfate+metformin Hydrochloride should be taken with caution in patients with kidney diseases. Consult your doctor if you have any concerns.
Children
unsafeLobeglitazone Sulfate+metformin Hydrochloride is not recommended for use in children as the safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
- Eat at regular intervals. Avoid a long gap between a meal or snack.
- Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
- Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
- Lose weight gradually to achieve a healthy body mass index.
- Replace refined carbohydrates-containing foods with whole grain foods and increase fruits, vegetables and other fibre-rich foods.
- Reduce saturated fat intake (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking.
- Avoid stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress.
- Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc).
- Try to quit smoking and reduce intake of carbohydrate-rich food like potato, rice, mangoes, bread, sugar, etc.
Patients Concern
Disease/Condition Glossary
Type 2 diabetes mellitus: It is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilization of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin, or in later stages, your body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite and dry mouth. This condition may worsen over time and cause toxic effects if not properly treated.
FAQs
Lobeglitazone Sulfate+metformin Hydrochloride belongs to the group of medications called antidiabetic agents; used to treat type 2 diabetes mellitus.
Lobeglitazone Sulfate+metformin Hydrochloride is a combination of two medicines: Lobeglitazone sulfate and Metformin hydrochloride. Lobeglitazone sulfate improves blood sugar control by making fat cells more responsive to insulin through peroxisome proliferator-activated receptor (PPAR) activation. Metformin hydrochloride acts by decreasing liver glucose production and intestinal glucose uptake. Together, Lobeglitazone Sulfate+metformin Hydrochloride helps control blood sugar levels.
Hypoglycemia refers to low blood glucose levels. Lobeglitazone Sulfate+metformin Hydrochloride may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, exercise excessively.
Do not stop taking Lobeglitazone Sulfate+metformin Hydrochloride without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Lobeglitazone Sulfate+metformin Hydrochloride for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lobeglitazone Sulfate+metformin Hydrochloride.
If you miss a dose, try to take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Avoid taking the double dose as it might cause unpleasant side effects or overdose.
You should include balanced diet to help manage your blood sugar levels effectively. Take foods high in fiber, like vegetables, fruits, whole grains, and legumes. Include steamed, boiled or baked food in your diet. Drink minimum 8 to 10 glasses of water every day. Carry a fruit or high fiber low-calorie biscuits while travelling. However, consult your doctor if you have any concerns.
Store the Lobeglitazone Sulfate+metformin Hydrochloride at room temperature away from direct sunlight, heat and moisture. Make sure to keep it out of the reach of children and pets.
The common side effects of Lobeglitazone Sulfate+metformin Hydrochloride are hypoglycemia, weight gain, swelling, headache, stomach pain, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.
