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Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate

About Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate

Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is used to treat pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, such as acetaminophen. Pain in osteoarthritis (OA) of the knee is a type of chronic pain that occurs when the cartilage in the knee joint breaks down, causing bone to rub against bone. This leads to inflammation, stiffness, and pain in the knee, making everyday activities like walking, climbing stairs, and even standing difficult.

Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate contains Hylan polymers, which replicate the natural hyaluronic acid found in the joint, helping to cushion and lubricate the joint, reduce friction and inflammation, and promote healing and repair of damaged tissue. The other ingredients, including sodium chloride, disodium hydrogen phosphate, and sodium dihydrogen phosphate monohydrate, help maintain the stability and effectiveness of the Hylan polymers.

In some cases, Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate may cause common side effects such as pain, swelling, heat, redness, fluid build-up around the knee, headache, nausea, dizziness, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not receive Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate if you have had an allergic reaction to Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate or any of its components. Inform your doctor if you have a joint infection or skin disease in the affected area. Also inform your doctor if you have chondrocalcinosis (accumulation of calcium pyrophosphate dihydrate crystals in and around the joints), blood clots, bleeding problems, blood circulation problems, or heart, kidney, or liver problems. Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is not recommended for people below 21 years. Consult your doctor if you are pregnant or breastfeeding. The safety and efficacy of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate have not been established for use in joints other than the knee.

Uses of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate

Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is used to treat pain in osteoarthritis. The detailed use of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is as follows: • Treatment of Pain: Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is used to treat pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, such as acetaminophen.

Medicinal Benefits

The combination of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate provides relief from osteoarthritis knee pain by lubricating and cushioning the joint, reducing friction and inflammation. It replenishes the natural hyaluronan in the joint, enhances joint mobility and flexibility, and may reduce inflammation and swelling in the affected joint, making everyday activities easier.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate

  • Pain
  • Swelling
  • Heat
  • Redness
  • Fluid build-up around the knee
  • Headache
  • Nausea
  • Dizziness
  • Stomach pain

Drug Warnings

Do not take Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate if you are allergic to Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate or any of its components, or if you have knee joint infections or skin disease in the area of the injection site. Inform your doctor if you have chondrocalcinosis (accumulation of calcium pyrophosphate dihydrate crystals in and around the joints), blood clots, bleeding problems, blood circulation problems, or heart, kidney, or liver problems. Avoid driving or operating machinery unless you are alert, as it may cause dizziness and drowsiness. You are recommended not to consume alcohol along with Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate to avoid unpleasant side effects. Consult your doctor if you are pregnant or breastfeeding. Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is not recommended for people below 21 years.

Drug Interactions

Drug-Drug Interaction: Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate may interact with disinfectants (cetylpyridinium, benzalkonium chloride), anticoagulants (apixaban, dabigatran, edoxaban), and tyrosine kinase inhibitors (cabozantinib, acalabrutinib).

Drug-Food Interaction: You are advised not to consume alcohol along with Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate to avoid unpleasant side effects.

Drug-Disease Interaction: Inform your doctor if you have chondrocalcinosis (accumulation of calcium pyrophosphate dihydrate crystals in and around the joints), blood clots, bleeding problems, blood circulation problems, or heart, kidney, or liver problems before receiving Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate.

Drug-Drug Interactions Checker List:

  • BENZALKONIUM CHLORIDE
  • CETYLPYRIDINIUM
  • APIXABAN
  • DABIGATRAN
  • EDOXABAN
  • CABOZANTINIB
  • ACALABRUTINIB
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended not to consume alcohol along with Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate to avoid unpleasant side effects.

    • Safety Warning

      Pregnancy

      caution

      Please inform your doctor if you are pregnant, as the safety and effectiveness of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate in pregnant women have not been established.

    • Safety Warning

      Breast Feeding

      caution

      Please inform your doctor if you are breastfeeding, as the safety and effectiveness of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate in nursing mothers have not been established.

    • Safety Warning

      Driving

      caution

      In some cases, Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate may cause dizziness and drowsiness. So, drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      If you have liver impairment, consult your doctor, as the safety and efficacy of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate in such cases is unknown.

    • Safety Warning

      Kidney

      caution

      If you have kidney impairment, consult your doctor, as the safety and efficacy of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate in such cases is unknown.

    • Safety Warning

      Children

      unsafe

      Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is not recommended for people below 21 years of age, as the safety and effectiveness have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
    • Acupuncture, massage and physical therapy may also be helpful.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Avoid smoking and alcohol consumption.

    Patients Concern

    Disease/Condition Glossary

    Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints, and ligament injuries.

    FAQs

    Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is used to treat pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, such as acetaminophen. Pain in osteoarthritis (OA) of the knee is a type of chronic pain that occurs when the cartilage in the knee joint breaks down, causing bone to rub against bone. This leads to inflammation, stiffness, and pain in the knee, making everyday activities like walking, climbing stairs, and even standing difficult.

    Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate contains Hylan polymers, which replicate the natural hyaluronic acid found in the joint, helping to cushion and lubricate the joint, reduce friction and inflammation, and promote healing and repair of damaged tissue. The other ingredients, including sodium chloride, disodium hydrogen phosphate, and sodium dihydrogen phosphate monohydrate, help maintain the stability and effectiveness of the Hylan polymers.

    Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate is specifically approved for injection into the knee joint to treat osteoarthritis pain. The safety and effectiveness of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate in joints other than the knee have not been established through clinical trials. Therefore, its use in other joints, such as the hip, ankle, shoulder, or elbow, is not recommended and should be avoided.

    Hyaluronic acid is a natural viscous gel fluid found in the joints of the body. This fluid works as a lubricant and shock absorber for smooth movement. It reduces friction and provides lubrication. When hyaluronic acid gets reduced, it causes the bone to rub together, leading to pain, stiffness, and other symptoms associated with osteoarthritis.

    After receiving Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate, avoid jogging or high-impact sports like soccer or tennis, and refrain from weight-bearing activities or standing for extended periods (longer than 1 hour at a time). Consult your doctor if you have any concerns about post-injection activities, as they may provide personalized advice based on your specific condition and needs.

    Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate contains a combination of Hylan polymers, sodium chloride, disodium hydrogen phosphate, and sodium dihydrogen phosphate monohydrate.

    No, Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate should only be administered by a healthcare professional, such as a doctor or nurse, in a clinical setting. Self-administration is not recommended.

    To store Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate properly, keep it in its original packaging, protect it from light, and store it at room temperature below 86°F (30°C). It's essential to avoid freezing it.

    The common side effects of Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate may include pain, swelling, heat, redness, fluid build-up around the knee, headache, nausea, dizziness, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

    Available Medicines for

    Hylan Polymers+sodium Chloride+disodium Hydrogen Phosphate+sodium Dihydrogen Phosphate Monohydrate

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