Gliclazide+sitagliptin
About Gliclazide+sitagliptin
Gliclazide+sitagliptin belongs to the category of medications called 'anti-diabetics' primarily used for the treatment of type 2 diabetes. Type 2 diabetes is a chronic condition characterized by the body's impaired ability to regulate glucose levels, resulting from abnormal insulin production or utilization, leading to high blood sugar levels.
Gliclazide+sitagliptin contains Gliclazide and Sitagliptin. Gliclazide stimulates the release of insulin from pancreatic beta cells, increasing insulin secretion and reducing glucose levels in the blood. Sitagliptin enhances the body's natural response to high blood sugar by increasing the levels of incretin hormones, which boosts insulin release and decreases glucagon levels in the circulation. Together, Gliclazide+sitagliptin helps treat type 2 diabetes.
Take Gliclazide+sitagliptin as prescribed by the doctor. Your doctor will recommend how often you need to take Gliclazide+sitagliptin based on your medical condition. In some cases, you may experience side effects like stomach ache, indigestion, constipation, nausea, vomiting, upper respiratory tract infections, headache, and nasopharyngitis (inflammation of nasal passages). Most of these side effects of Gliclazide+sitagliptin do not require medical attention and gradually resolve over time. However, consult the doctor if you experience these side effects persistently.
Do not take Gliclazide+sitagliptin if you are allergic to any of its ingredients. Gliclazide+sitagliptin is not recommended for children below 18 years of age. Consult your doctor if you are pregnant, breastfeeding, or planning to become pregnant before taking Gliclazide+sitagliptin. Inform your doctor about your pre-existing medical conditions and if you are taking any other medications to prevent interactions. Do not take or discontinue Gliclazide+sitagliptin unless advised by the doctor.
Uses of Gliclazide+sitagliptin
Gliclazide+sitagliptin is used in the treatment of type 2 diabetes mellitus. The detailed uses of Gliclazide+sitagliptin are as follows: <br/> • Treatment of type 2 diabetes: Gliclazide+sitagliptin is used to treat type 2 diabetes by stimulating insulin release from the pancreas, helping to decrease blood glucose levels effectively.<br/> • Regulation of blood sugar levels: Gliclazide+sitagliptin regulates blood sugar levels by maintaining proper glucose and insulin balance in the body.<br/>
Medicinal Benefits
Gliclazide+sitagliptin belongs to the class of medicines called anti-diabetic drugs, indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). It contains Gliclazide and Sitagliptin. Gliclazide stimulates the release of insulin from pancreatic beta cells, increasing insulin secretion and reducing glucose levels in the blood. Sitagliptin enhances the body's natural response to high blood sugar by increasing the levels of incretin hormones, which in turn boosts insulin release and decreases glucagon levels in the circulation. Together, Gliclazide+sitagliptin helps treat type 2 diabetes.
Directions for Use
Storage
Side Effects of Gliclazide+sitagliptin
- Stomach ache
- Indigestion
- Constipation
- Upper respiratory tract infections
- Headache
- Nasopharyngitis (inflammation of nasal passages)
- Nausea
- Vomiting
Drug Warnings
Do not take Gliclazide+sitagliptin if you are allergic to any of its components. Inform the doctor if you have type 1 diabetes, severe liver/kidney disease, pancreatitis, gallstones, diabetic ketoacidosis, alcoholism, heart problems, high triglycerides, G6PD deficiency, or hemolytic anaemia. Consult the doctor if you are pregnant or breastfeeding before taking Gliclazide+sitagliptin. Let your doctor know if you are taking other medications, including supplements or herbal products, to rule out potential interactions.
Drug Interactions
Drug-Drug Interaction: Inform the doctor if you are taking antibacterial drugs (clarithromycin), medications to treat high blood pressure or heart failure (captopril, enalapril), antifungal (miconazole, fluconazole), antacids (ranitidine), antidepressants (selegiline, phenelzine), painkillers (ibuprofen, phenylbutazone), anti-inflammatory medications (hydrocortisone, prednisolone), blood thinner (warfarin), anti-diabetic (insulin glargine), diuretic (furosemide), hormone (levothyroxine), or cardiac glycoside (digoxin).
Drug-Food Interaction: No interactions found/established.
Drug-Disease Interaction: Inform the doctor if you have diabetic ketoacidosis, type-1 diabetes, pancreatitis, heart problems, severe liver or kidney problems, diabetic coma, severe thyroid or adrenal gland problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consuming alcohol as it can cause hypoglycemia.
Pregnancy
cautionPlease consult the doctor if you are pregnant or think you may be pregnant. The doctor will decide if it is safe to take Gliclazide+sitagliptin during pregnancy.
Breast Feeding
cautionIt is not known if this medicine passes into breast milk. Consult the doctor if you are breastfeeding.
Driving
cautionLow/high blood glucose levels may impair your driving skills and concentration. Be cautious when driving or engaging in activities that require mental alertness.
Liver
cautionGliclazide+sitagliptin should be used with caution in patients with severe liver disease. Consult the doctor if you have liver problems.
Kidney
cautionGliclazide+sitagliptin should be used with caution in patients with severe kidney disease. Consult the doctor if you have kidney problems.
Children
cautionGliclazide+sitagliptin is not recommended for use in children. Please consult the doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Eat a well-balanced diet by including whole, unprocessed foods like fruits, vegetables, whole grains, and pulses.
- Maintain proper weight by losing weight if you're overweight or obese.
- Quit smoking, as it may exacerbate diabetes complications.
- Eating smaller, more frequent meals can help manage blood sugar levels.
- Manage stress through relaxation techniques such as yoga or deep breathing.
- Get enough sleep, as poor sleep can negatively affect blood sugar levels.
Patients Concern
Disease/Condition Glossary
Type 2 diabetes: Type 2 diabetes is a chronic condition characterised by insulin resistance and potential insulin deficiency. As the body struggles to use insulin effectively, it resorts to alternative energy sources. Symptoms include increased hunger, fatigue, weight loss, excessive thirst, frequent urination, dry mouth, itchy skin, and blurred vision. Type 2 diabetes is commonly known as adult-onset diabetes as it typically affects middle-aged and older adults. If left unmanaged, type 2 diabetes poses serious complications, including blindness, amputation, nerve damage, kidney problems, sexual dysfunction, and a heightened risk of heart attack or stroke.
FAQs
Gliclazide+sitagliptin belongs to the category of 'anti-diabetic' medications used for the treatment of type 2 diabetes.
Gliclazide+sitagliptin contains Gliclazide and Sitagliptin. Gliclazide stimulates the release of insulin from pancreatic beta cells, increasing insulin secretion and reducing glucose levels in the blood. Sitagliptin enhances the body's natural response to high blood sugar by increasing the levels of incretin hormones, which in turn boosts insulin release and decreases glucagon levels in the circulation. Together, Gliclazide+sitagliptin helps treat type 2 diabetes.
If you experience symptoms of low blood sugar, such as weakness, dizziness, sweating or shaking, quickly consume sugar-rich foods like candies or sugary drinks to stabilize your blood sugar levels.
Gliclazide+sitagliptin may not be recommended for children as the safety and efficacy have not been established. Please consult the doctor if you have any concerns.
Gliclazide+sitagliptin may cause side effects like stomach ache, indigestion, constipation, nausea, vomiting, upper respiratory tract infections, headache, and nasopharyngitis (inflammation of nasal passages). Most of these side effects of Gliclazide+sitagliptin do not require medical attention and gradually resolve over time. However, consult the doctor if you experience any of these side effects persistently.
No. Gliclazide+sitagliptin is not recommended for the treatment of type 1 diabetes. It is only indicated for the treatment of type 2 diabetes, also called non-insulin-dependent diabetes.
If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact a doctor, as it may indicate that you have diabetes.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables if you have diabetes.
Abruptly stopping Gliclazide+sitagliptin can lead to increased blood sugar levels. Therefore, do not stop taking Gliclazide+sitagliptin even if you feel well. Continue the prescribed duration of treatment to manage your condition effectively.
