Omeprazole+domperidone
About Omeprazole+domperidone
Domperidone+omeprazole is used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome.
Domperidone+omeprazole is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the contractions of the stomach muscles. Together, Domperidone+omeprazole helps in treating acidity.
Take Domperidone+omeprazole 30-60 minutes prior to food. In some cases, you may experience certain common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. Consult your doctor before taking Domperidone+omeprazole if you are pregnant or breastfeeding. Domperidone+omeprazole may cause sleepiness, so drive only if you are alert. Domperidone+omeprazole should not be given to children as safety has not been established. Avoid consuming alcohol along with Domperidone+omeprazole as it could lead to increased drowsiness and can elevate the production of stomach acid.
Uses of Omeprazole+domperidone
Medicinal Benefits
- Helps relieve symptoms of acid reflux, heartburn, and gastroesophageal reflux disease (GERD).
- Reduces excessive stomach acid production.
- Prevents acid-related damage to the stomach and oesophagus lining.
- Promotes faster stomach emptying and reduces nausea, bloating, and vomiting.
- Provides relief from gastritis, indigestion, and acid-related discomfort.
- Helps prevent and heal stomach and duodenal ulcers.
- Improves digestion and reduces the feeling of fullness after meals.
- Enhances overall gastrointestinal comfort and quality of life when taken as prescribed.
Directions for Use
- Domperidone+omeprazole should be taken before meals, about 15-30 minutes before breakfast or dinner.
- It is usually taken twice daily or as prescribed by your doctor.
- Swallow Domperidone+omeprazole as a whole with a glass of water.
- Do not crush or chew this medication.
Storage
Side Effects of Omeprazole+domperidone
- Dry mouth
- Stomach pain
- Diarrhoea
- Headache
- Flatulence
Drug Warnings
- Do not take Domperidone+omeprazole if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment.
- Inform your doctor before taking Domperidone+omeprazole if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools.
- Talk to your doctor before taking Domperidone+omeprazole if you have osteoporosis as Domperidone+omeprazole may increase the risk of bone fractures on long-term treatment.
- Consult your doctor before taking Domperidone+omeprazole if you are pregnant or breastfeeding.
- Domperidone+omeprazole may cause sleepiness, so drive only if you are alert.
- Domperidone+omeprazole should not be given to children as safety has not been established.
- Avoid consuming alcohol along with Domperidone+omeprazole as it could lead to increased drowsiness and can elevate the production of stomach acid.
Drug Interactions
Drug-Drug Interactions: Domperidone+omeprazole may interact with painkillers (aspirin), antibiotics (ciprofloxacin), statin (atorvastatin), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), a drug used to treat hypothyroidism (levothyroxine), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, escitalopram, duloxetine), anti-anxiety (alprazolam), vitamin (cyanocobalamin), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), cardiac glycoside (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, or hypomagnesemia (low levels of magnesium).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Domperidone+omeprazole. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Pregnancy
consult your doctorConsult your doctor before taking Domperidone+omeprazole if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
consult your doctorDomperidone+omeprazole may pass into breast milk. Consult your doctor before taking Domperidone+omeprazole; your doctor will decide whether Domperidone+omeprazole can be taken by breastfeeding mothers or not.
Driving
cautionDomperidone+omeprazole may cause sleepiness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed. Consult your doctor before taking Domperidone+omeprazole if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed. Consult your doctor before taking Domperidone+omeprazole if you have kidney impairment or any concerns regarding this.
Children
unsafeDomperidone+omeprazole should not be given to children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
- Maintain a healthy weight through regular exercise.
- Avoid lying down after eating, as this can cause acid reflux.
- Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
- Practise relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid high-fat foods, spicy foods, chocolate, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
- Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.
Special Advise
- Inform your doctor before taking Domperidone+omeprazole if you are due to have Chromogranin A test.
- Domperidone+omeprazole may cause changes in a blood test to check liver functioning. Inform the person doing the tests that you are taking Domperidone+omeprazole.
- Talk to your doctor before taking Domperidone+omeprazole if you have osteoporosis as Domperidone+omeprazole may increase the risk of bone fractures on long-term treatment.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.
Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion
Zollinger-Ellison syndrome: It is characterised by tumours in the upper part of the small intestine that lead to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.
FAQs
Domperidone+omeprazole is used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome.
Domperidone+omeprazole contains Omeprazole and Domperidone. Omeprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the contractions of the stomach muscles. Together, Domperidone+omeprazole helps in treating acidity.
Diarrhoea might be a side-effect of Domperidone+omeprazole. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Dry mouth could be a side effect of Domperidone+omeprazole. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent mouth dryness.
Domperidone+omeprazole contains domperidone, which helps in treating nausea and vomiting. However, Domperidone+omeprazole is used to treat acidity. Please consult your doctor; he/she may prescribe an alternative treatment for nausea and vomiting.
Do not take Domperidone+omeprazole for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Domperidone+omeprazole for 14days.
Domperidone+omeprazole is usually safe and well-tolerated, with minimal side effects that are typically mild and temporary. To get the most out of this medication, be sure to follow healthy habits and take Domperidone+omeprazole exactly as directed by your doctor. This way, you can enjoy the benefits of this medication while minimising any potential side effects.
The contraindications of Domperidone+omeprazole should be used cautiously and under medical supervision. Certain health conditions, medications, or situations may interact with this medication. It's essential to consult a healthcare professional for personalised advice and treatment. They will help determine the appropriate use and ensure safe administration.
Take Domperidone+omeprazole as directed by your healthcare professional. Typically, it's best to take it before meals, about 15-30 minutes before breakfast, or at bedtime if prescribed twice daily. This helps reduce symptoms like nausea and vomiting. However, always follow your healthcare provider's specific instructions for your needs.
Domperidone+omeprazole may rarely cause an abnormal heartbeat, especially in people with pre-existing heart conditions. However, by following your doctor's advice on taking medication, maintaining healthy lifestyle habits, and attending regular check-ups, you can minimise the risks and ensure safe treatment.
Store Domperidone+omeprazole in a cool, dry place away from sunlight. Keep it out of reach and sight of children.
Take Domperidone+omeprazole exactly as your doctor advises. Swallow it whole with water, without chewing or crushing. Follow the prescribed dose and schedule, and don't exceed the recommended duration. If you need more clarification, consult your doctor.
Consult your doctor before taking Domperidone+omeprazole if you have liver problems. Your doctor may adjust the dose or monitor you closely, as domperidone and omeprazole can affect liver function. It's essential to follow their advice to ensure safe treatment.
Common side effects of Domperidone+omeprazole may include dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Domperidone+omeprazole can interact with other medications, so it's essential to consult your doctor before taking any other medicines. Do not club any other medications with Domperidone+omeprazole unless advised by your doctor. Your doctor will check for potential interactions and only advise additional medications if necessary. This will help avoid any harmful interactions and ensure safe treatment.
Domperidone+omeprazole is a combination medication that contains two active ingredients: Omeprazole, a Proton Pump Inhibitor, and Domperidone, a Dopamine Antagonist.
GERD (Gastroesophageal Reflux Disease) is a condition in which stomach acid flows back into the oesophagus, causing heartburn, a sour or bitter taste, and difficulty swallowing. This acid reflux irritates the oesophagus, leading to uncomfortable symptoms.
No, it's not recommended to take Domperidone+omeprazole on your own without consulting a doctor. This medication is prescription-only and requires a doctor's supervision to ensure safe and effective treatment. Your doctor will assess your condition and medical history to determine the appropriate dosage and duration of treatment.
You should take Domperidone+omeprazole for as long as your doctor recommends, which is usually based on your medical condition and response to treatment. Always follow their advice and do not exceed the recommended treatment period without consulting your doctor.
Avoid drinking alcohol while taking Domperidone+omeprazole, as it may worsen side effects like drowsiness and dizziness and reduce the medication's effectiveness. To ensure safe treatment, it's best to avoid alcohol or consult your doctor for guidance.
No, unless recommended by your doctor. Consult your doctor before taking Domperidone+omeprazole if you are pregnant or breastfeeding, as it may not be suitable for you. Your doctor will assess the risks and benefits and guide you on the safest treatment options for you and your baby.
