Since this affects multiple family members, it could be a hereditary condition like Restless Legs Syndrome (RLS) or familial nocturnal leg cramps. Because leg pain can stem from various causes-including circulation issues, nerve compression, or electrolyte imbalances-I cannot safely recommend a specific prescription medication without a proper medical evaluation.\n\nFor immediate, non-medicinal relief, try gentle calf stretches before sleep, staying well-hydrated, and applying warm compresses to the affected leg. Over-the-counter magnesium supplements may help ease cramps, but please consult a healthcare professional first. I highly recommend scheduling a doctor's visit for a proper physical exam and accurate diagnosis.