It is common for a high fever to take 24 to 48 hours to respond after starting antibiotics like ofloxacin. Since you started only yesterday, the medication needs more time to target the underlying infection. To help lower your temperature now, try tepid sponging (wiping your body with a cloth dampened in room-temperature water) and drink plenty of fluids to stay hydrated. Continue taking your paracetamol safely, but do not exceed the recommended daily dose. If your fever remains this high after 48 hours of starting treatment, or if you experience warning signs like breathing difficulties or extreme weakness, please consult your doctor immediately for a reassessment.