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  3. Zedruff Shampoo

Zedruff Shampoo, Pack of 1 Shampoo
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Zedruff Shampoo is an antifungal medication used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. It works by damaging the fungal cell membranes and killing fungi. Some people may experience side effects such as itching, redness, irritation, or a burning sensation at the site of application.

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Composition :

KETOCONAZOLE-2%W/V + ZINC PYRITHIONE-1%W/V

Manufacturer/Marketer :

Minova Life Sciences Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

About Zedruff Shampoo

Zedruff Shampoo belongs to a class of dermatological medication called 'antifungal,' primarily used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. Dandruff is a mild scalp condition that causes white or yellow flakes and itching, usually due to excess oil, fungal overgrowth, or sensitivity to hair products. Seborrheic dermatitis is a more severe form that can affect other oily areas like the face, ears, and chest, leading to red, inflamed skin with greasy, yellowish scales.

Zedruff Shampoo contains Ketoconazole and zinc pyrithione. Ketoconazole is an antifungal agent that disrupts the fungal cell membrane, preventing the growth of dandruff-causing fungi, while zinc pyrithione is a broad-spectrum antimicrobial that inhibits fungal and bacterial growth, reducing scalp irritation and flaking. Their combined action helps control scalp infections, reduce inflammation, and restore scalp health.

Use Zedruff Shampoo exactly as prescribed by the doctor. Your doctor will recommend how often you need to use Zedruff Shampoo based on your medical condition. Some people may experience itching, redness, irritation, or a burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zedruff Shampoo or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Zedruff Shampoo. Avoid contact of Zedruff Shampoo with the nose, ears, mouth, or eyes. If Zedruff Shampoo accidentally comes into contact with these areas, rinse with water thoroughly. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately.

Uses of Zedruff Shampoo

Zedruff Shampoo is used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. The detailed uses of Zedruff Shampoo are as follows:<br/> • Dandruff treatment: Zedruff Shampoo helps reduce flakes, itching, and scalp irritation.<br/> • Seborrheic dermatitis management: Zedruff Shampoo supports control of redness and scaling on the scalp.<br/> • Fungal infection relief: Zedruff Shampoo helps in managing conditions caused by fungal overgrowth.<br/> • Localised tinea versicolor of the scalp: Zedruff Shampoo assists in treating fungal infections that cause discoloured patches on the scalp.<br/>

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Wet the area thoroughly before application. Massage into a lather, leave it on for a few minutes and rinse thoroughly with water.
  • Avoid contact of Zedruff Shampoo with nose, mouth or eyes. If it accidentally comes into contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Zedruff Shampoo is used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. It contains ketoconazole and zinc pyrithione. Ketoconazole is an antifungal agent which works by disrupting fungal cell membranes to stop their growth and spread. Zinc pyrithione has broad-spectrum antimicrobial properties that help in regulating sebum production, reducing excess oil that contributes to dandruff. Together, Zedruff Shampoo helps eliminate dandruff, soothe scalp irritation, and restore scalp health.

How Zedruff Shampoo Works

Zedruff Shampoo contains Ketoconazole and zinc pyrithione, which work together to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. Ketoconazole is an antifungal agent that disrupts the fungal cell membrane, preventing the growth of dandruff-causing fungi, while zinc pyrithione is a broad-spectrum antimicrobial that inhibits fungal and bacterial growth, reducing scalp irritation and flaking. Their combined action helps control scalp infections, reduce inflammation, and restore scalp health.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zedruff Shampoo out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zedruff Shampoo

Do not use Zedruff Shampoo in excessive amounts or for a longer time than recommended, as it does not yield quicker or better results, but instead increases the risk of side effects. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to Zedruff Shampoo or any other medicines, please tell your doctor. Avoid contact of Zedruff Shampoo with nose, mouth or eyes. In case Zedruff Shampoo comes in contact with these areas accidentally, rinse with water thoroughly. Do not swallow Zedruff Shampoo. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Zedruff Shampoo. Zedruff Shampoo is not recommended for children below 12 years, as the safety and effectiveness have not been established.

Diet & Lifestyle Advise

  • To fight inflammation (swelling and redness), eat foods rich in anti-inflammatory properties, such as tomatoes, olive oil, plenty of green, leafy vegetables, strawberries, cherries, blueberries, bell peppers, sweet potatoes, almonds, avocados, and wheat germ.
  • Take fish oil supplements, as they help suppress flare-ups of dermatitis triggered by allergies and boost overall immunity.
  • Regularly wash the affected areas with a mild shampoo.
  • Use conditioners, shampoos and other products containing tea tree oil as they might help to relieve itching.
  • Avoid styling hair sprays and gels during a flare.
  • Avoid alcohol-based products as they trigger a reaction.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - TOPICAL

Zedruff Shampoo Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of Zedruff Shampoo with alcohol is unknown. Please consult a doctor before consuming alcohol while using Zedruff Shampoo.

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Pregnancy

Caution

Please inform your doctor before using Zedruff Shampoo if you are pregnant or plan to become pregnant. Your doctor will prescribe it only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Zedruff Shampoo is excreted in human milk. Please consult a doctor before using Zedruff Shampoo while breastfeeding.

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Driving

Not applicable

Zedruff Shampoo usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of Zedruff Shampoo in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Zedruff Shampoo in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Zedruff Shampoo is not recommended for children below 12 years, as the safety and effectiveness were not established.

Have a query?

FAQs

Zedruff Shampoo belongs to a class of dermatological medication called 'antifungal,' primarily used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis.

Zedruff Shampoo contains Ketoconazole and zinc pyrithione. Ketoconazole is an antifungal agent that disrupts the fungal cell membrane, preventing the growth of dandruff-causing fungi, while zinc pyrithione is a broad-spectrum antimicrobial that inhibits fungal and bacterial growth, reducing scalp irritation and flaking. Their combined action helps control scalp infections, reduce inflammation, and restore scalp health.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close, direct contact until the infection is clear and avoid sharing things with the infected person, as this can also spread the infection.

Yes, you may be advised to stop using cream or lotion containing steroids such as hydrocortisone or betamethasone before using Zedruff Shampoo. However, inform your doctor if you are using any steroidal creams or lotions before using this lotion so that the dose of steroidal cream may be reduced gradually to avoid flaring up the condition while using it.

It is recommended that you use Zedruff Shampoo for as long as your doctor has prescribed it. However, if the condition persists or worsens after 2 to 4 weeks of treatment with Zedruff Shampoo, please consult a doctor.

No, you are not recommended to stop using Zedruff Shampoo without consulting your doctor, as it may cause recurring infections. Therefore, take Zedruff Shampoo for as long as your doctor has prescribed it, and if you experience any difficulty while taking it, please consult your doctor.

Yes, it is for use on the scalp.

The common side effects of Zedruff Shampoo may include itching, redness, irritation, or a burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Nanhera Rd, Kuldeep Nagar, Nanhera,Ambala Cantt, Haryana 133001
Other Info - ZE64534

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 22, 2025 | 8:54 AM IST

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Reference

  1. https://rwandafda.gov.rw/wp-content/uploads/2024/02/Keto%20Plus%20Shampoo%20-%20Ketoconazole%20BP%202%20and%20Zinc%20Pyithione%201%20-%20PIL.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bd06b9fa-00a2-4ad5-b54c-0ce1eab32fa7
  3. https://www.efda.gov.et/wp-content/uploads/2023/10/Ketoconazole-USP-20-mg-and-Zinc-pyrithione-suspension-48-_Dermazole-Plus-Shampoo_Kusum-Healthcare-Pvt.-Ltd.pdf

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