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compositionComposition:LIDOCAINE-100MG
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Xylocaine 10% Spray is used to reduce/relieve pain and discomfort associated with skin irritation, burns, scratches, insect bites, skin abrasions, or sunburn. It is also used to treat post-herpetic neuralgia, premature ejaculation, pain in urethritis (inflammation of the urethra), and as an adjunct for endotracheal intubation. It contains Lidocaine, which produces local numbness by blocking the nerve signal in the affected area. In some cases, it may cause application site reactions such as burning sensation, itching, redness, and irritation.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LIDOCAINE-100MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Xylocaine 10% Spray

Xylocaine 10% Spray is a topical numbing spray that temporarily reduces sensation in the skin or mucous membranes. It may be used to relieve minor pain, itching, or discomfort from conditions such as minor burns, scrapes, or insect bites, and may also be used to numb a specific area before certain minor procedures. By temporarily blocking pain signals from the treated area, it provides localized relief without affecting the entire body.

Apply Xylocaine 10% Spray only as directed by your doctor or according to the product instructions. Avoid using it over large areas or more often than recommended, as too much medicine can be absorbed into the bloodstream and cause serious side effects. The treated skin should generally be clean and dry before application. Wearing loose clothing over the area can help reduce rubbing and irritation.

Most people tolerate Xylocaine 10% Spray well when it is used correctly. Mild redness, tingling, burning, or temporary numbness may occur at the application site and usually settles after the medicine wears off. However, seek urgent medical attention if you develop severe dizziness, confusion, difficulty breathing, bluish skin, severe skin reactions, or other serious symptoms. For life-threatening symptoms, call emergency services (112 in India).

Before using Xylocaine 10% Spray, tell your doctor if you have broken, infected, or severely irritated skin, severe liver disease, heart rhythm problems, or a history of reactions to local anesthetics. Do not use it if you are allergic to Xylocaine 10% Spray or other local anesthetic medicines.

Certain heart medicines and other local anesthetics may increase the risk of side effects when used with Xylocaine 10% Spray. Tell your doctor or pharmacist about all medicines and numbing products you use. If you are pregnant, breastfeeding, or an older adult, ask your healthcare provider whether this medicine is appropriate for you.

Uses of Xylocaine 10% Spray

Xylocaine 10% Spray is used to treat the pain (during surgical procedures and injections). The detailed uses of Xylocaine 10% Spray are as follows:

  • Minor skin pain and itching: Xylocaine 10% Spray temporarily numbs nerve endings in the treated skin, helping relieve discomfort from minor burns, cuts, scrapes, or insect bites when appropriate for the specific product.
  • Pre-procedural numbing: Some Xylocaine 10% Spray sprays are used to temporarily numb the skin or mucous membranes before certain minor medical or dental procedures. Use only the formulation and dose recommended by your healthcare professional.
  • Premature ejaculation: Some specifically formulated Xylocaine 10% Spray sprays are approved or designed to reduce penile sensitivity and help delay ejaculation. Premature ejaculation is a common and treatable concern, and discussing it with a healthcare professional can help identify suitable treatment. A general topical Xylocaine 10% Spray spray should not be substituted for a product specifically formulated for this purpose because the strength, dose, and instructions may differ.

Key Benefits

  • Xylocaine 10% Spray provides localized, temporary relief by acting directly on the area where it is applied. This can help reduce discomfort without requiring an oral pain medicine.
  • It can help make activities more comfortable by reducing minor pain, itching, or sensitivity in the treated area.
  • When used for an appropriate medical or procedural purpose, its numbing action can help reduce discomfort during minor procedures.
  • For specifically formulated products used for premature ejaculation, reducing penile sensitivity may help some people delay ejaculation and feel more confident during sexual activity.

Directions for Use

  • Use Xylocaine 10% Spray as prescribed by your physician.
  • Clean and dry the affected area.
  • Point the nozzle towards the application site and press the button to spray.
  • Shake the container before use.
  • Do not puncture, incinerate, or break the container, even if it is empty.
  • Wash your hands before and after using Xylocaine 10% Spray.

How Xylocaine 10% Spray Works

Xylocaine 10% Spray is a local anesthetic that works mainly by blocking voltage-gated sodium channels in nerve cell membranes. These channels are needed for electrical signals to travel along nerves. By blocking them temporarily, Xylocaine 10% Spray prevents pain and other sensation signals from travelling normally to the brain, producing a localized numbing effect.
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Alcohol

Consult your doctor

It is unknown if alcohol affects Xylocaine 10% Spray. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Xylocaine 10% Spray only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether breastfeeding mothers can use Xylocaine 10% Spray or not.

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Driving

Consult your doctor

It is not known if Xylocaine 10% Spray affects your ability to drive. Drive only if you are alert after using Xylocaine 10% Spray.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Xylocaine 10% Spray is not recommended for children as efficacy and safety have not been established.

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Heart

Consult your doctor

Inform your doctor if you have heart disease before using Xylocaine 10% Spray. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Xylocaine 10% Spray may cause increased blood levels in the elderly with repeated use, which can raise the risk of side effects and may require dose adjustment by your doctor.

What if I have taken an overdose of Xylocaine 10% Spray

If you accidentally apply too much spray, or if anyone swallows the medicine, seek immediate medical attention or call a poison control center. Symptoms of absorbing too much of this medicine include dizziness, confusion, slow heart rate, or a numb feeling throughout the body.

Diet & Lifestyle Advise

  • Wear loose-fitting clothing: Avoid tight clothing over the treated area to reduce friction and irritation.
  • Avoid heating pads: Do not apply heating pads, hot compresses, or other direct heat to the treated area unless your healthcare professional specifically advises it, as increased heat may increase medicine absorption.
  • Protect numb skin: Reduced sensation can make it easier to overlook an injury. Avoid scratching, rubbing, or exposing the numbed area to extreme heat or cold.
  • Stay comfortable and hydrated: If you are using Xylocaine 10% Spray for a minor skin irritation, maintain good hydration and avoid environmental factors that may worsen the underlying irritation.

Health Queries

I have a wound in my throat that makes it difficult to swallow water. What tablet or syrup should I take for immediate relief?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

For immediate relief from throat pain, making it hard to swallow, you can use throat lozenges or sprays containing local anaesthetics like lidocaine to numb the area. Pain relievers like paracetamol or ibuprofen can also help reduce discomfort and inflammation. Additionally, gargling with warm salt water is a safe, soothing way to promote healing. Please avoid hot, spicy, or acidic foods. Because difficulty swallowing can lead to dehydration, it is highly recommended to consult a doctor for a proper evaluation to identify the cause and ensure safe recovery.

I have severe throat pain and cannot even swallow my saliva. What medication should I take for relief?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

For temporary pain relief, you can take over-the-counter pain relievers like paracetamol or ibuprofen, and use throat sprays or lozenges containing a local anaesthetic like lidocaine. However, being completely unable to swallow your saliva is a significant symptom that requires prompt medical evaluation. It often indicates severe swelling or an infection, such as tonsillitis or an abscess, which may require prescription medications like antibiotics or corticosteroids. Please visit an urgent care clinic or emergency room right away so a doctor can safely examine your throat and prescribe the appropriate targeted treatment.

I am experiencing watery semen and premature ejaculation, which is affecting my sexual performance. What medications or treatments can I take to improve my semen consistency and sexual stamina?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

It is very common to experience these issues, and both are highly treatable. Watery semen is often temporary and can be caused by frequent ejaculation, mild dehydration, or diet. Staying hydrated and consuming zinc-rich foods can help improve consistency. For premature ejaculation, behavioral techniques like the 'start-stop' method are highly effective. Medical options include over-the-counter desensitizing sprays containing lidocaine, or prescription medications such as selective serotonin reuptake inhibitors (SSRIs), like dapoxetine. I highly recommend consulting a doctor or urologist. They can rule out any minor underlying causes and safely guide you toward the best treatment plan for your body.
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How Soon It Starts Working

The time required for Xylocaine 10% Spray to start to work: Xylocaine 10% Spray ideally shows its action within 3 to 5 minutes after application.

The time for which the effects of Xylocaine 10% Spray last: The effect of Xylocaine 10% Spray lasts for 30 minutes to 3 hours.

Storage

• Store Xylocaine 10% Spray according to the storage instructions provided with your specific product.

What if you forget to take Xylocaine 10% Spray

Since Xylocaine 10% Spray is typically used on an as-needed basis, a missed dose is rarely a concern. If you are using it on a regular schedule and miss an application, apply it as soon as you remember. However, if it is nearly time for your next scheduled application, skip the missed dose and resume your regular schedule. Do not double the amount sprayed to make up for a missed application.

Drug Warnings

  • Check the nozzle: Make sure the spray nozzle is clean and functioning properly before use.
  • Do not apply to severely damaged skin: Avoid spraying onto deep wounds, extensively blistered skin, or severely infected areas unless specifically advised by a healthcare professional.
  • Keep away from the eyes: Do not spray directly into the eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with water.
  • Wash your hands: Clean your hands after application to prevent accidental transfer of the medicine to your eyes or other sensitive areas.
  • Use the correct formulation: Xylocaine 10% Spray sprays can differ in strength, ingredients, and approved uses. Use only the product prescribed or recommended for your particular condition.
  • Do not overuse: Using larger amounts or applying the spray more frequently than recommended increases the risk of serious side effects.
  • Premature ejaculation: If using Xylocaine 10% Spray for this concern, use only a product specifically formulated for this purpose. Do not substitute a general skin-numbing spray.
  • Children: This article is intended for adults. Xylocaine 10% Spray spray should be used in children only when specifically recommended and supervised by a healthcare professional.

Drug-Drug Interactions

verifiedApollotooltip
  • Heart rhythm medications: Combining Xylocaine 10% Spray with certain medicines used to treat abnormal heartbeats may increase the risk of heart-related side effects.
  • Other local anesthetics: Using other numbing creams, gels, or sprays alongside this product can lead to an accumulation of anesthetic in your body, increasing toxicity risks.
LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Xylocaine 10% Spray 50 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Saquinavir can increase the blood levels of Xylocaine 10% Spray 50 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Xylocaine 10% Spray 50 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LidocaineMetrizamide
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml and Metrizamide may increase the risk of causing seizures(fits).

How to manage the interaction:
Although taking Xylocaine 10% Spray 50 ml and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LidocaineRasburicase
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Rasburicase with Xylocaine 10% Spray 50 ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Xylocaine 10% Spray 50 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineMetoclopramide
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Coadministration of metoclopramide with Xylocaine 10% Spray 50 ml may increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between metoclopramide and Xylocaine 10% Spray 50 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as grey discolouration of the skin, nausea, headache, dizziness, weakness, breathing difficulty, rapid or shallow breathing, palpitation, anxiety, and confusion, consult a doctor. Do not stop using medications without a doctor's advice.
LidocaineIsosorbide dinitrate
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking isosorbide dinitrate with Xylocaine 10% Spray 50 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Xylocaine 10% Spray 50 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineDapsone
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Dapsone with Xylocaine 10% Spray 50 ml can increase the risk of methemoglobinemia (a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Xylocaine 10% Spray 50 ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
LidocaineBupropion
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with bupropion can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of bupropion along with Xylocaine 10% Spray 50 ml can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
LidocaineCyclophosphamide
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Cyclophosphamide may increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Although there is a possible interaction, cyclophosphamide can be taken with Xylocaine 10% Spray 50 ml if prescribed by the doctor. However, consult the doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue the medication without consulting a doctor.
LidocaineAmprenavir
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Amprenavir may increase the blood levels of Xylocaine 10% Spray 50 ml, which increases severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Xylocaine 10% Spray 50 ml and Amprenavir, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Xylocaine 10% Spray when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[LOCAL ANESTHETICS]

FAQs

Xylocaine 10% Spray belongs to the class of local anaesthetics used to reduce/relieve pain and discomfort. It also treats post-herpetic neuralgia (lasting pain after a shingles infection). It may also be used to treat premature ejaculation. It is also indicated for preventing and controlling pain in urethritis (inflammation of the urethra). Lidocaine may also be used as an adjunct for endotracheal intubation.
Xylocaine 10% Spray blocks the influx of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses (nerve signal). Hence, it provides an anaesthetic effect and decreases the sensation of pain.
Avoid concomitant use of Xylocaine 10% Spray with other topical products such as cosmetics, sunscreens, lotions, moisturizers, insect repellent creams, and other gels.
Do not apply Xylocaine 10% Spray on open wounds, injured skin, or unhealed shingles blisters. Apply Xylocaine 10% Spray on intact skin only.
Avoid using Xylocaine 10% Spray for longer durations unless prescribed by the doctor. If your condition does not improve even after using Xylocaine 10% Spray for 7 days, consult your doctor.
Xylocaine 10% Spray generally begins producing numbness within a few minutes, but the exact onset depends on the formulation, amount used, application site, and reason for use. Some products may act more quickly on superficial skin, while deeper or mucosal applications can vary. Follow the instructions for your specific product.
Avoid tight bandages, plastic coverings, or other occlusive dressings unless your doctor specifically recommends them. Covering the area can increase absorption. If protection is needed, ask your doctor or pharmacist what type of covering is appropriate.
Some Xylocaine 10% Spray products may provide temporary relief from minor sunburn discomfort, but not all sprays are approved for this use. Do not apply it to severely blistered, extensively damaged, or infected skin unless advised by a healthcare professional.
The answer depends on the formulation and why you are using it. Some products may be used for a limited period under medical guidance, while others are intended only for occasional use. Do not use Xylocaine 10% Spray every day or for prolonged periods without following the product instructions or your doctor's advice.
Rinse your eyes thoroughly with plenty of clean water and avoid rubbing them. Because Xylocaine 10% Spray can temporarily numb the eye, be careful not to scratch it. Seek medical advice if pain, irritation, blurred vision, or other symptoms persist.
If you are pregnant, planning to become pregnant, or breastfeeding, discuss Xylocaine 10% Spray use with your healthcare provider. Your doctor can consider the specific formulation, amount required, application area, and potential benefits and risks before recommending it.
Temporary paleness or redness may occur where Xylocaine 10% Spray is applied and usually settles as the medicine wears off. Persistent discoloration, severe irritation, or significant skin changes should be assessed by a healthcare professional.
There is no major direct food interaction with topical Xylocaine 10% Spray, but excessive alcohol use may worsen dizziness or drowsiness if enough Xylocaine 10% Spray is absorbed into the bloodstream. It is best to ask your healthcare provider if you are unsure about alcohol use during treatment.

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Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - XYL0130
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