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Reviewed By Santoshini Reddy G , M Pharmacy
Uptrol Plus Capsule is a combination medicine primarily used to treat nutritional deficiencies, low calcium levels (hypocalcaemia), vitamin B6 deficiency, folate deficiency, and vitamin B12 deficiency. This medicine works by increasing the calcium and vitamin D levels in the body and regulates bodily functions, thus providing essential nutrients necessary for bone formation and maintenance. Common side effects include upset stomach, diarrhoea, drowsiness, flushing, and nausea.
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About Uptrol Plus Capsule

Uptrol Plus Capsule is used to treat nutritional deficiencies. Nutritional deficiency occurs when the body is unable to absorb or get enough nutrients from food. It could lead to various health problems, including defective bone growth, skin disorders, digestive issues, and dementia (memory loss). 

Uptrol Plus Capsule contains Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. Calcium carbonate makes the bones stronger by increasing their density. Calcitriol raises the Vitamin D levels and thereby increases calcium levels in the blood. Folic acid helps in producing new blood cells and prevents low folate levels. Vitamin B6 is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis. 

Your doctor will decide the duration based on your medical condition. Sometimes, Uptrol Plus Capsule may cause common side effects like nausea, stomach upset, and diarrhoea. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult a doctor.

Let your doctor know if you use any other medicines before starting Uptrol Plus Capsule . If you are allergic to any of the components in Uptrol Plus Capsule , please inform your doctor. If you are pregnant or breastfeeding, please consult your doctor before taking Uptrol Plus Capsule . It is advised to avoid or limit alcohol consumption since it may affect calcium absorption. Uptrol Plus Capsule should not be given to children unless advised by a doctor.

Uses of Uptrol Plus Capsule

Management and treatment of Nutritional deficiencies

Directions for Use

• Take Uptrol Plus Capsule in the morning with breakfast or as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow it as a whole with a glass of water.• Do not break, crush or chew it.

Medicinal Benefits

Uptrol Plus Capsule is used to treat nutritional deficiencies and contains Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. Calcium carbonate makes the bones stronger by increasing their density. It helps treat and prevent low calcium levels. Calcitriol is a synthetic version of Vitamin D3 that treats calcium deficiency and improves Vitamin D levels. Folic acid helps form red blood cells and prevents DNA changes that lead to cancer. Vitamin B6 is a water-soluble vitamin involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis.

How Uptrol Plus Capsule Works

Uptrol Plus Capsule contains Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. Calcium carbonate makes the bones stronger by increasing their density. Calcitriol raises the Vitamin D levels and thereby increases calcium levels in the blood. Folic acid helps in producing new blood cells and prevents low folate levels. Vitamin B6 is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
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Side effects of Uptrol Plus Capsule
  • Stay hydrated by drinking plenty of water.
  • Avoid dairy product such as cheese, milk, yogurt and ice cream.
  • Maintain healthy weight and exercise daily.
  • Following a low-calcium diet can help reduce hypercalcemia symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Uptrol Plus Capsule

Avoid exceeding the recommended dose as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food) before starting Uptrol Plus Capsule . Let your doctor know if you have any heart/kidney/liver diseases or hypercalcaemia (excess calcium levels in the blood) before starting Uptrol Plus Capsule . If you are pregnant or breastfeeding, consult your doctor before taking Uptrol Plus Capsule . Drinking alcohol may hinder Uptrol Plus Capsule absorption; therefore, it is advised to limit the alcohol intake while using Uptrol Plus Capsule .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Uptrol Plus Capsule:
Coadministration of Uptrol Plus Capsule and Cholestyramine may interfere with the absorption of Uptrol Plus Capsule.

How to manage the interaction:
Although taking Cholestyramine and Uptrol Plus Capsule together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Trimethoprim may decrease the blood levels and effects of Uptrol Plus Capsule.

How to manage the interaction:
Although there is a possible interaction between Uptrol Plus Capsule and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with Uptrol Plus Capsule:
Coadministration of Uptrol Plus Capsule and Carbamazepine may reduce the blood levels of Uptrol Plus Capsule.

How to manage the interaction:
Although there is a possible interaction between Uptrol Plus Capsule and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
How does the drug interact with Uptrol Plus Capsule:
Coadministration of Uptrol Plus Capsule and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Uptrol Plus Capsule and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
How does the drug interact with Uptrol Plus Capsule:
Sulfadiazine may decrease the blood levels and effects of Uptrol Plus Capsule.

How to manage the interaction:
Although there is a possible interaction between Uptrol Plus Capsule and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Uptrol Plus Capsule with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Uptrol Plus Capsule and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Uptrol Plus Capsule and Digoxin may increase the calcium levels may increase the effects of Digoxin

How to manage the interaction:
Although there is an interaction, Uptrol Plus Capsule can be taken with Digoxin if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
Calcium carbonatePatiromer calcium
Severe
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Uptrol Plus Capsule may lower the effectiveness of Patiromer calcium in binding potassium.

How to manage the interaction:
Although there is an interaction, Uptrol Plus Capsule can be taken with Patiromer calcium if prescribed by the doctor. Consult the prescriber if you experience symptoms such as metabolic alkalosis like nausea, vomiting, tremor, muscle twitching, lightheadedness, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, and confusion. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Dolutegravir with Uptrol Plus Capsule can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although there is an interaction, Uptrol Plus Capsule can be taken with dolutegravir if prescribed by the doctor. However, dolutegravir and Uptrol Plus Capsule should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Uptrol Plus Capsule with Ketoconazole may decrease the effects of Ketoconazole.

How to manage the interaction:
Although there is an interaction, Uptrol Plus Capsule can be taken with Ketoconazole if prescribed by the doctor. However, maintain a gap of 2 or more hours between both medicines. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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CALCITRIOL-0.25MCG+CALCIUM CARBONATE-200MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+VITAMIN B6-3MGPotassium rich foods
Moderate

Drug-Food Interactions

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CALCITRIOL-0.25MCG+CALCIUM CARBONATE-200MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+VITAMIN B6-3MGPotassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
Consumption of Spinach while on the treatment with Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine may decrease the blood levels of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine. Avoid or limit consumption of Spinach while on the treatment with Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine.

Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.

  • Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid.

  • Include fruits like citrus, banana, and watermelon in your diet.

  • Avoid smoking and alcohol consumption.

  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT
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Alcohol

Caution

It is advised to limit/avoid alcohol intake to ensure maximum absorption of nutrients.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant. Your doctor will recommend this medicine only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Pyridoxine is excreted into breast milk. Please consult your doctor before taking Uptrol Plus Capsule if you are a breastfeeding mother.

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Driving

Safe

Uptrol Plus Capsule usually does not interfere with your driving ability.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Uptrol Plus Capsule . Your dosage may be adjusted in case of liver impairment.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Uptrol Plus Capsule . Your dosage may be adjusted in case of renal impairment.

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Children

Caution

Do not use this medicine in children without recommended by your doctor.

Have a query?

FAQs

Uptrol Plus Capsule is used to treat and manage nutritional deficiencies.

Uptrol Plus Capsule is a vitamin supplement and consists of Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. When you lack these vitamins in your body, Uptrol Plus Capsule helps replenish these deficient levels. Collectively, Uptrol Plus Capsule treats nutritional deficiencies.

Pyridoxine/Vitamin B6 in Uptrol Plus Capsule may interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Uptrol Plus Capsule before undergoing blood and urine examinations.

Avoid taking more than one multivitamin product concomitantly unless advised by the doctor. Taking similar nutritional supplements simultaneously can lead to a vitamin overdose or other serious side effects.

Antacids may interfere with the absorption of Uptrol Plus Capsule . Hence, taking Uptrol Plus Capsule two hours before or four hours after taking antacids is advised.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Avoid or limit alcohol consumption while taking Uptrol Plus Capsule since it may affect calcium absorption. Let your doctor know if you are using antacids, anti-cancer drugs (altretamine, fluorouracil, capecitabine), fits medicines (phenytoin, phenobarbital), antibiotics (ceftriaxone, ketoconazole), HIV/AIDS medicines (dolutegravir), hormones (levothyroxine), water pills, high blood pressure medicines (diltiazem), and heart-related medicines (digoxin) as Uptrol Plus Capsule may interact with these medicines.

Calcium is essential for building and maintaining strong bones, supporting muscle movement, facilitating nerve communication and blood vessel movement, and releasing hormones that impact various body functions.

The amount of calcium you need depends on your age, sex and other factors. However, consult your doctor if you have any concerns.

The amount of calcium in your blood is determined via a calcium blood test. Blood calcium levels that are too high or too low can indicate a variety of illnesses, including kidney disease, thyroid disease, parathyroid abnormalities, bone disease, and more. Consult a doctor to help to assess the test results after receiving your report.

Yes, excess calcium can be harmful. It can lead to a condition called hypercalcemia, which occurs when there is too much calcium in the blood. Symptoms of hypercalcemia include excessive thirst, frequent urination, nausea, vomiting, constipation, abdominal pain, muscle weakness, confusion, and in severe cases, heart rhythm problems. If you experience any of these symptoms, please consult your doctor.

To manage low calcium levels, increase calcium intake from dairy, leafy greens, almonds, and fortified foods. Take calcium and vitamin D supplements only if suggested by your doctor. Get enough vitamin D and monitor calcium levels regularly. However, consult your doctor if you have any concerns.

It best to take any multivitamins after breakfast in the morning for better nutritional absorption. However, take Uptrol Plus Capsule as advised by your doctor.

The common side effects of Uptrol Plus Capsule are nausea, stomach upset, and diarrhoea. If these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

#12-13-677/94,Kimtee Colony,Tarnaka,Secunderabad-500017
Other Info - UPT0005

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