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Uptrol Plus Capsule is a combination medicine primarily used to treat nutritional deficiencies, low calcium levels (hypocalcaemia), vitamin B6 deficiency, folate deficiency, and vitamin B12 deficiency. This medicine works by increasing the calcium and vitamin D levels in the body and regulates bodily functions, thus providing essential nutrients necessary for bone formation and maintenance. Common side effects include upset stomach, diarrhoea, drowsiness, flushing, and nausea.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Athiko Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Uptrol Plus Capsule

Uptrol Plus Capsule is a nutritional supplement suggested to treat or prevent calcium deficiency, support bone metabolic health, and address certain vitamin B deficiencies. It is commonly used for conditions like osteoporosis, osteomalacia, and joint health support, as well as maintaining healthy nerve function. This combination helps ensure your bones receive adequate calcium while supporting red blood cell production and nerve health.


To get the best results, you should take Uptrol Plus Capsule consistently at the same time every day as directed by your doctor. It is typically taken with food to improve the absorption of calcium and minimise any potential stomach upset. Combining this medicine with a balanced diet rich in calcium and regular, low-impact exercise can significantly enhance its benefits.


While taking Uptrol Plus Capsule , some people may experience mild side effects like mild stomach upset, bloating, or constipation. If you notice persistent vomiting, severe muscle weakness, or signs of high calcium levels in your blood, contact your doctor immediately.


Do not take this if you have high calcium levels in your blood or urine, or severe kidney disease. Talk to your doctor before starting Uptrol Plus Capsule if you have a history of kidney stones, heart disease, or sarcoidosis.


This medicine can interact with certain antibiotics, thyroid medicines, and alcohol, which may decrease its effectiveness or increase side effects. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider to ensure this supplement is safe for your specific needs.

Uses of Uptrol Plus Capsule

Uptrol Plus Capsule is used in the treatment and management of the following conditions:

  • Osteoporosis and bone weakness: Uptrol Plus Capsule helps by providing essential calcium and active vitamin D to strengthen bones, reduce bone loss, and lower the risk of fractures.
  • Calcium and Vitamin D deficiency: It restores low levels of calcium and active vitamin D3 in the body, which are vital for maintaining healthy skeletal structure and muscle function.
  • Nutritional deficiencies and anaemia: It helps replenish vital B-vitamins needed for healthy red blood cell formation, preventing fatigue and weakness associated with anaemia.
  • Neuropathy and nerve pain: The active B-vitamins in this supplement support the repair and maintenance of myelin (the protective covering around nerves), helping to reduce nerve pain and numbness.

Key Benefits

Uptrol Plus Capsule offers several benefits by supporting bone health, nerve function, and overall nutritional well-being.

  • Supports stronger bones and joints: It provides a highly absorbable form of calcium combined with active vitamin D, helping your body absorb calcium more efficiently. This supports stronger bones and joints, improves mobility, and may help reduce discomfort associated with bone mineral loss.
  • Promotes nerve health: The essential B-vitamins in this combination help support nerve repair and maintenance, reducing tingling, numbness, and burning sensations in the hands and feet. This can improve daily physical function and mobility.
  • Supports healthy red blood cell production: Folic acid, vitamin B6, and methylcobalamin help support the formation of healthy red blood cells, reducing fatigue and weakness associated with nutritional deficiencies and certain types of anaemia.
  • Helps improve energy levels: By correcting nutritional deficiencies and supporting healthy blood cell production, it may help improve overall energy levels and reduce chronic fatigue.
Side effects of Uptrol Plus Capsule
  • Stay hydrated by drinking plenty of water.
  • Avoid dairy product such as cheese, milk, yogurt and ice cream.
  • Maintain healthy weight and exercise daily.
  • Following a low-calcium diet can help reduce hypercalcemia symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Take Uptrol Plus Capsule in the morning with breakfast or as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not break, crush, or chew it.

How Uptrol Plus Capsule Works

Uptrol Plus Capsule contains calcium carbonate, calcitriol, folic acid, vitamin B6, and methylcobalamin, which work together to support bone health, nerve function, and red blood cell production. Calcium carbonate provides a rich source of elemental calcium, which is the primary building block for strong, dense bones and helps maintain normal muscle and nerve function. Calcitriol is the active form of vitamin D3 that helps increase the absorption of calcium from the intestines into the bloodstream, ensuring adequate calcium levels for healthy bones and teeth. Folic acid supports healthy cell growth and development and plays an important role in the formation of red blood cells. It also helps maintain healthy levels of homocysteine (an amino acid that, at high levels, may increase the risk of heart and nerve problems). Vitamin B6 helps the body utilise proteins and supports the production of neurotransmitters and red blood cells. It also works with folic acid to help maintain healthy homocysteine levels. Methylcobalamin is an active form of vitamin B12 that helps protect and repair nerve fibres while supporting the production of healthy red blood cells and normal nervous system function.
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Alcohol

Caution

It is advised to limit/avoid alcohol intake to ensure maximum absorption of nutrients.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant. Your doctor will recommend this medicine only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Pyridoxine is excreted into breast milk. Please consult your doctor before taking Uptrol Plus Capsule if you are a breastfeeding mother.

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Driving

Safe

Uptrol Plus Capsule usually does not interfere with your driving ability.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Uptrol Plus Capsule . Your dosage may be adjusted in case of liver impairment.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Uptrol Plus Capsule . Your dosage may be adjusted in case of renal impairment.

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Children

Caution

Do not use this medicine in children without recommended by your doctor.

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Heart

Consult your doctor

Inform your doctor if you have a history of heart disease. Your doctor will recommend only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Uptrol Plus Capsule should be given to elderly patients only when recommended by a doctor. If you have any concerns, please consult a doctor.

What if I have taken an overdose of Uptrol Plus Capsule

If you take too much of this medicine, you may experience severe nausea, vomiting, extreme thirst, or confusion. Seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat calcium-rich foods: Include calcium-rich foods in your diet, such as dairy products, leafy green vegetables, and fortified foods, to complement the supplement's effects.
  • Engage in regular exercise: Engage in regular weight-bearing exercises, like walking, jogging, or resistance training, to help strengthen your bones and improve balance.
  • Ensure adequate sun exposure: Ensure you get safe, moderate sun exposure to help your body naturally synthesise vitamin D, which supports calcium absorption.
  • Limit certain foods and beverages: Limit your intake of caffeine, sodas, and high-sodium foods, as these can interfere with how your body absorbs and retains calcium.
  • Avoid alcohol and smoking: Avoid excessive alcohol consumption and quit smoking, as both can weaken bone structure and worsen nerve damage.
health query

Have a query?

How Soon It Starts Working

The time required for Uptrol Plus Capsule to start to work: The time required for Uptrol Plus Capsule to show its action is unknown. The time for which the effects of Uptrol Plus Capsule last: The duration of action for Uptrol Plus Capsule is unknown.

Storage

•Store Uptrol Plus Capsule at room temperature, ideally between 15°C and 30°C (59°F to 86°F).•Keep the tablets in their original packaging to protect them from direct light, heat, and moisture.

What if you forget to take Uptrol Plus Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Check the packaging before use: Always check the packaging before use to ensure the tablets are intact and have not expired.
  • Inform your doctor about kidney stones: Inform your doctor if you have a history of kidney stones, as the calcium in this supplement might increase the risk of developing new stones.
  • Monitor calcium levels regularly: Monitor your blood and urine calcium levels regularly if your doctor schedules routine lab tests to ensure your levels remain in a safe range.
  • Be cautious with other supplements: Be cautious if you are taking other vitamin supplements; taking additional calcium, vitamin D, or B-complex vitamins alongside Uptrol Plus Capsule can lead to accidental toxicity.
  • Inform healthcare providers: Let all of your healthcare providers, including dentists and specialists, know that you are taking Uptrol Plus Capsule before undergoing any procedures or starting new suggesteds.

Drug-Drug Interactions

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  • Certain antibiotics (like tetracyclines and quinolones): Calcium can bind to these drugs, reducing their absorption. Take these antibiotics at least 2 hours before or 4 to 6 hours after taking Uptrol Plus Capsule .
  • Thyroid medicines (like levothyroxine): Calcium can decrease the absorption of thyroid hormone. Separate the doses by at least 4 hours.
  • Thiazide diuretics (water pills): Taking these with Uptrol Plus Capsule may increase the risk of developing excessively high calcium levels in your blood.
  • Antiseizure medicines (like phenytoin): These can speed up the breakdown of vitamin D in your body, lowering the effectiveness of Uptrol Plus Capsule .

Drug-Drug Interactions

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How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Digitoxin may decrease the blood levels of Digitoxin.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Digitoxin, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Gefitinib can decrease the blood levels of Gefitinib.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Gefitinib, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Raltegravir can decrease the blood levels of Raltegravir.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Raltegravir, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Capecitabine may increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, dizziness, fever consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Rifapentine can decrease the blood levels of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Rifapentine, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Colecalciferol can lead to increase in side effects.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Colecalciferol, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms like weakness, tiredness, headache, drowsiness, loss of hunger, ringing sound in the ears, nausea, vomiting, difficulty in passing stools, dry mouth, muscle pain or metallic taste, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Carbamazepine may decrease the blood levels of Carbamazepine.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Carbamazepine, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Ergocalciferol can lead to increase in side effects.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Ergocalciferol, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms like weakness, tiredness, headache, drowsiness, loss of hunger, ringing sound in the ears, nausea, vomiting, difficulty in passing stools, dry mouth, muscle pain or metallic taste, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Fluorouracil can lead to increase in side effects.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Fluorouracil, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms like nausea, vomiting, loose stools, tiredness, weakness, dizziness, fainting, unusual bleeding or bruising, blood in stools, chills fever, mouth ulcers or tingling sensation hands or feet, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Uptrol Plus Capsule:
Co-administration of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Burosumab may increase phosphorus and vitamin D levels in the blood.

How to manage the interaction:
There may be a possibility of interaction between Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine with Burosumab, but it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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  • High-fibre foods, spinach, and whole grains: These foods contain phytates or oxalates (natural compounds that can reduce calcium absorption), which can bind to calcium and reduce how much of it your body absorbs. Avoid consuming them within 2 hours of taking your supplement.
CALCITRIOL-0.25MCG+CALCIUM CARBONATE-200MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+VITAMIN B6-3MGPotassium rich foods
Moderate

Drug-Food Interactions

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CALCITRIOL-0.25MCG+CALCIUM CARBONATE-200MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+VITAMIN B6-3MGPotassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
Consumption of Spinach while on the treatment with Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine may decrease the blood levels of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine. Avoid or limit consumption of Spinach while on the treatment with Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine.

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Uptrol Plus Capsule is used to treat and manage nutritional deficiencies.
Uptrol Plus Capsule is a vitamin supplement and consists of Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. When you lack these vitamins in your body, Uptrol Plus Capsule helps replenish these deficient levels. Collectively, Uptrol Plus Capsule treats nutritional deficiencies.
Pyridoxine/Vitamin B6 in Uptrol Plus Capsule may interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Uptrol Plus Capsule before undergoing blood and urine examinations.
Avoid taking more than one multivitamin product concomitantly unless advised by the doctor. Taking similar nutritional supplements simultaneously can lead to a vitamin overdose or other serious side effects.
Antacids may interfere with the absorption of Uptrol Plus Capsule . Hence, taking Uptrol Plus Capsule two hours before or four hours after taking antacids is advised.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Avoid or limit alcohol consumption while taking Uptrol Plus Capsule since it may affect calcium absorption. Let your doctor know if you are using antacids, anti-cancer drugs (altretamine, fluorouracil, capecitabine), fits medicines (phenytoin, phenobarbital), antibiotics (ceftriaxone, ketoconazole), HIV/AIDS medicines (dolutegravir), hormones (levothyroxine), water pills, high blood pressure medicines (diltiazem), and heart-related medicines (digoxin) as Uptrol Plus Capsule may interact with these medicines.
Calcium is essential for building and maintaining strong bones, supporting muscle movement, facilitating nerve communication and blood vessel movement, and releasing hormones that impact various body functions.
The amount of calcium you need depends on your age, sex and other factors. However, consult your doctor if you have any concerns.
The amount of calcium in your blood is determined via a calcium blood test. Blood calcium levels that are too high or too low can indicate a variety of illnesses, including kidney disease, thyroid disease, parathyroid abnormalities, bone disease, and more. Consult a doctor to help to assess the test results after receiving your report.
Yes, excess calcium can be harmful. It can lead to a condition called hypercalcemia, which occurs when there is too much calcium in the blood. Symptoms of hypercalcemia include excessive thirst, frequent urination, nausea, vomiting, constipation, abdominal pain, muscle weakness, confusion, and in severe cases, heart rhythm problems. If you experience any of these symptoms, please consult your doctor.
To manage low calcium levels, increase calcium intake from dairy, leafy greens, almonds, and fortified foods. Take calcium and vitamin D supplements only if suggested by your doctor. Get enough vitamin D and monitor calcium levels regularly. However, consult your doctor if you have any concerns.
It best to take any multivitamins after breakfast in the morning for better nutritional absorption. However, take Uptrol Plus Capsule as advised by your doctor.
The common side effects of Uptrol Plus Capsule are nausea, stomach upset, and diarrhoea. If these side effects persist or worsen, please consult your doctor.
It is highly recommended to take Uptrol Plus Capsule with a meal. Food helps your stomach produce acid, which improves the absorption of calcium carbonate, and it also helps prevent mild stomach upset. Talk to your doctor or pharmacist if you struggle to take it with food.
If you are pregnant or breastfeeding, your nutritional needs change, and high doses of certain vitamins or calcium may not be suitable. You should consult your healthcare provider to see if Uptrol Plus Capsule is appropriate for you. Talk to your doctor before starting this supplement.
Yes, the calcium component in Uptrol Plus Capsule can sometimes cause mild constipation. You can manage this by drinking plenty of water throughout the day, eating a high-fibre diet, and staying physically active. If constipation persists, talk to your doctor.
A mild metallic taste or dry mouth can sometimes happen when taking vitamin and mineral supplements. Staying hydrated by drinking water frequently can help ease these symptoms. If these side effects become bothersome or severe, talk to your doctor.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

#12-13-677/94,Kimtee Colony,Tarnaka,Secunderabad-500017
Other Info - UPT0005
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