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Trascepa 1000 Softgel Capsule is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Icosapent Ethyl, which works by decreasing the amount of triglycerides and other fats made in the liver. You may experience side effects like musculoskeletal pain, peripheral oedema, constipation, gout, atrial fibrillation, arthralgia (pain in a joint), and oropharyngeal (middle part of the throat) pain.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Adn Lifesciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trascepa 1000 Softgel Capsule

Trascepa 1000 Softgel Capsule is a prescription medicine used to lower high triglyceride (fat) levels in adults and to reduce the risk of heart attack, stroke, and other cardiovascular events in certain people at increased cardiovascular risk. It is commonly prescribed alongside a heart-healthy diet and other cholesterol-lowering treatments.

For the best results, you need to take Trascepa 1000 Softgel Capsule regularly and consistently as prescribed by your doctor. You should always take this medication with food or a meal to help your body absorb it properly. Combining this treatment with a low-fat diet and regular physical exercise is key to successfully managing your lipid levels.

While taking Trascepa 1000 Softgel Capsule , some people may experience mild side effects like joint pain or mild swelling in the hands and feet. However, you should consult your doctor immediately if you experience more serious symptoms, such as an irregular heartbeat or unusual bleeding.

Before starting this medicine, talk to your doctor if you have a history of liver damage, heart rhythm problems, or a fish allergy. Do not take this if you are allergic to any of the ingredients in Trascepa 1000 Softgel Capsule .

Some medications, particularly blood thinners, can interact with Trascepa 1000 Softgel Capsule and increase your risk of bleeding. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider to discuss whether this treatment is safe for you.

Uses of Trascepa 1000 Softgel Capsule

Your doctor may prescribe Trascepa 1000 Softgel Capsule to treat the following conditions to help lower triglyceride levels, reduce cardiovascular risk, and improve heart health:

  • Severe high triglycerides: Reduces very high levels of fats (triglycerides) in the blood in adults.
  • Cardiovascular risk reduction: Lowers the risk of serious heart issues, such as heart attacks, strokes, or the need for heart surgery, in adults who have elevated triglyceride levels, take cholesterol-lowering medicines, and have established heart disease or diabetes with other risk factors.

Key Benefits

Using Trascepa 1000 Softgel Capsule as prescribed helps lower triglyceride levels, protect your heart, and support long-term cardiovascular health. Here are the key benefits you can expect:

  • Lowers high triglyceride levels: Helps reduce very high triglyceride levels, supporting healthier blood lipid levels.
  • Protects cardiovascular health: Helps lower the risk of serious cardiovascular events, such as heart attack, stroke, and certain heart procedures, in people at high cardiovascular risk.
  • Supports comprehensive lipid management: Helps lower triglycerides without increasing LDL ('bad') cholesterol levels, making it an effective addition to your overall cholesterol management plan.
Side effects of Trascepa 1000 Softgel Capsule
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Throat pain can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Consider taking lozenges or hard candy throat pain relievers, which give a soothing effect.
  • Take enough rest and stay in warm places to reduce pain quickly.

Directions for Use

  • Trascepa 1000 Softgel Capsule can be taken with food or as advised by the doctor.
  • It is usually recommended to take twice daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow Trascepa 1000 Softgel Capsule as a whole with water.
  • Do not crush, break or chew it.

How Trascepa 1000 Softgel Capsule Works

Trascepa 1000 Softgel Capsule contains Icosapent ethyl, a highly purified omega-3 fatty acid. Although its exact mechanism of action is not fully understood, it is believed to work through several complementary pathways, including reducing the liver's production and release of triglycerides, improving the removal of triglycerides from the bloodstream, and supporting healthy cardiovascular function. These combined effects help lower triglyceride levels and reduce the risk of major cardiovascular events, such as heart attack and stroke, in appropriate patients.
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Alcohol

Unsafe

While using this medication, avoid consuming alcohol because it can elevate triglyceride levels and increase your risk of liver damage.

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Pregnancy

Unsafe

Trascepa 1000 Softgel Capsule is not recommended during pregnancy as it may cause major birth defects.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking Trascepa 1000 Softgel Capsule .

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Driving

Safe

Trascepa 1000 Softgel Capsule has negligible influence on the ability to drive and use machines.

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Liver

Caution

Caution should be exercised while using Trascepa 1000 Softgel Capsule in patients with hepatic impairment. Your doctor may monitor levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). So, inform your doctor before receiving Trascepa 1000 Softgel Capsule if you have had a liver impairment.

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Kidney

Caution

It has not been studied in patients with kidney impairment. So, inform your doctor before receiving Trascepa 1000 Softgel Capsule if you have had kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Trascepa 1000 Softgel Capsule is not recommended for children younger than 18 years old.

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Heart

Safe if prescribed

Trascepa 1000 Softgel Capsule is generally safe for heart patients if prescribed, but should be used under medical supervision.

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Geriatrics

Consult your doctor

Limited information available about the use of Trascepa 1000 Softgel Capsule in geriatric patients. Please consult your physician.

What if I have taken an overdose of Trascepa 1000 Softgel Capsule

If you suspect that you or someone else has taken more than the prescribed dose of Trascepa 1000 Softgel Capsule , seek immediate medical attention right away.

Diet & Lifestyle Advise

  • Follow a heart-healthy diet: Choose foods that are low in saturated fats, trans fats, and cholesterol to support healthy lipid levels.
  • Eat fibre-rich foods: Include vegetables, oats, whole grains, legumes, and other high-fibre foods in your daily meals to help improve your cholesterol and triglyceride levels.
  • Limit alcohol intake: Avoid or significantly reduce alcohol consumption, as it can increase triglyceride levels.
  • Reduce added sugars: Limit foods and drinks high in simple sugars, such as sweets, desserts, and sugar-sweetened beverages, as they can raise triglyceride levels.
  • Maintain a healthy lifestyle: Aim for at least 150 minutes of moderate-intensity physical activity, such as brisk walking, each week, or follow your doctor's recommendations.
health query

Have a query?

How Soon It Starts Working

The time required for Trascepa 1000 Softgel Capsule to start to work: The time required for Trascepa 1000 Softgel Capsule to show its action is not clinically established.

The time for which the effects of Trascepa 1000 Softgel Capsule last: The duration of action for Trascepa 1000 Softgel Capsule is not clinically established.

Storage

•Store Trascepa 1000 Softgel Capsule at 20°C to 25°C (68°F to 77°F) in its original container to protect it from moisture.

What if you forget to take Trascepa 1000 Softgel Capsule

If you miss a dose, take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Drug Warnings

  • Inspect before use: Check the capsules before each use. Do not take any capsule that is leaking, damaged, or discoloured.
  • Inform your healthcare providers: Tell your dentist and all treating doctors that you are taking Trascepa 1000 Softgel Capsule , as it may increase the risk of bleeding during surgical or dental procedures.
  • Monitor your heart rhythm: If you have a history of an irregular heartbeat, check your pulse regularly and contact your doctor immediately if you experience palpitations, fluttering, dizziness, or fainting.
  • Report allergies: Inform your doctor before starting treatment if you have a known allergy to fish or shellfish.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin) or antiplatelet drugs (such as aspirin or clopidogrel): May increase the risk of bleeding when taken together with Trascepa 1000 Softgel Capsule .
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • High-fat or low-fat meals: Trascepa 1000 Softgel Capsule must always be taken with food, as taking it on an empty stomach significantly reduces how well your body absorbs the medication.
ICOSAPENT ETHYL-1000MGTyramine-containing food

Drug-Food Interactions

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ICOSAPENT ETHYL-1000MGTyramine-containing food
Common Foods to Avoid:
Fish

How to manage the interaction:
It is obtained from oil of fish and has a risk of allergy in patients with known hypersensitivity. Patients with known hypersensitivity to fish and/or shellfish should discontinue Trascepa 1000 Softgel Capsule and seek medical attention if any reactions occur.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

FAQs

Trascepa 1000 Softgel Capsule is used together with lifestyle changes (diet, weight loss, exercise) to lower high cholesterol or increased cholesterol levels and triglycerides in the blood.
Trascepa 1000 Softgel Capsule contains Icosapent Ethyl work, which works by decreasing the amount of triglycerides and other fats made in the liver.
In a clinical investigation, Trascepa 1000 Softgel Capsule was known to cause an increased risk of bleeding. Patients taking antithrombotic drugs such as aspirin, clopidogrel, or warfarin had a higher risk of bleeding. If you have any concerns, please consult your healthcare practitioner.
There is no strong evidence to suggest that taking Trascepa 1000 Softgel Capsule will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if you are likely to get pregnant or are pregnant.
Increase your daily diet with fibre, fruits, vegetables, whole grains and fish, and cut saturated fat as well. Stop smoking and drinking, and try to work out every day as well.
No, you should not stop taking Trascepa 1000 Softgel Capsule without consulting your doctor. Please take advice from the doctor before quitting.
Yoghurt is a probiotic that can help lower the raised cholesterol level if taken with Trascepa 1000 Softgel Capsule . Yoghurt eaters have a better metabolic profile than those who do not eat yoghurt.
You should tell your doctor if you have a fish or shellfish allergy before taking Trascepa 1000 Softgel Capsule . They will help you decide if it is safe for you to use. Talk to your doctor.
Yes, you should always take Trascepa 1000 Softgel Capsule with a meal or food. This ensures that the medication is absorbed properly by your body. Talk to your doctor.
No. Trascepa 1000 Softgel Capsule is a prescription medicine that contains highly purified eicosapentaenoic acid (EPA) only. Most over-the-counter fish oil supplements contain a mixture of EPA and docosahexaenoic acid (DHA) in varying amounts and are not approved as substitutes for prescription Trascepa 1000 Softgel Capsule in reducing cardiovascular risk or treating severe high triglyceride levels. Talk to your doctor before replacing one with the other.
No, clinical studies show that Trascepa 1000 Softgel Capsule does not raise your low-density lipoprotein (LDL or "bad") cholesterol levels, unlike some other omega-3 products. Talk to your doctor.
Unusual bruising, frequent nosebleeds, or bleeding gums can be signs of an increased risk of bleeding. You should report these symptoms to your healthcare provider right away. Talk to your doctor.
You should limit or avoid alcohol, as drinking alcohol can raise your triglyceride levels and decrease the overall effectiveness of your treatment. Talk to your doctor.
The safety of Trascepa 1000 Softgel Capsule during pregnancy is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you should discuss the risks and benefits with your healthcare provider. Talk to your doctor.

Disclaimer

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Country of origin

India
Other Info - TRA1044
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