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Systaflam Spray is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. It blocks the release of certain chemical messengers in the brain that are responsible for causing pain and symptoms of inflammation, redness, and swelling. Additionally, it works on the brain and spinal cord centres to relieve muscle spasms and improve muscle pain and movement. It may cause side effects such as a burning sensation, irritation, itching and redness at the application site. Do not apply it to wounded or damaged skin.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Systaflam Spray

Systaflam Spray is a topical pain relief spray designed to ease localized discomfort in your muscles and joints. It is commonly suggested to treat acute pain arising from muscle spasms, strains, sprains, and joint stiffness. By delivering active ingredients directly through the skin, it provides targeted relief right at the source of pain.

For optimal results, Systaflam Spray is typically applied to the affected area three to four times a day, or as directed by your healthcare professional. Consistency is key when treating ongoing inflammation, but you should avoid applying it more frequently than recommended. Because this is a topical spray, it can be used without regard to food, though keeping hydrated and performing light, doctor-approved stretches can significantly improve your recovery progress.

While Systaflam Spray is generally well-tolerated, some individuals may experience mild local skin reactions such as redness, itching, or a temporary burning sensation. If you develop severe skin peeling, blistering, swelling, or signs of a serious allergic reaction, you should seek immediate medical attention. Always consult your doctor if any unexpected side effects persist or worsen.

Before you begin using Systaflam Spray, it is important to inform your doctor if you have a history of stomach ulcers, asthma, or kidney disease. Do not take this if you have open wounds, active skin infections, or if you have ever had a severe allergic reaction to aspirin or other anti-inflammatory medications. It is not recommended for young children unless advised by a pediatrician.

You should also discuss with your doctor if you are taking oral pain relievers or blood thinners, as combining them with topical treatments may increase the risk of side effects. Avoid smoking or using Systaflam Spray near open flames due to its flammable nature, and limit alcohol consumption to reduce the risk of stomach irritation. Pregnant, breastfeeding, or elderly individuals must consult their healthcare provider before using this product.

Uses of Systaflam Spray

Systaflam Spray is used in the treatment of pain and inflammation associated with musculoskeletal and joint disorders. The detailed uses of Systaflam Spray are as follows:

  • Muscle Spasms: Systaflam Spray helps to relieve acute muscle stiffness and painful contractions by relaxing local muscle fibers.
  • Joint Pain and Stiffness: Systaflam Spray targets inflammation in localized joints, helping to improve range of motion and ease discomfort from minor arthritis.
  • Sprains and Strains: Systaflam Spray provides rapid relief from localized pain and swelling caused by sudden muscle pulls, twists, or sports injuries.
  • Backache and Neck Pain: Systaflam Spray penetrates deep into tissues to soothe aching muscles along the spine, upper back, and neck.

Key Benefits

Systaflam Spray helps relieve localized muscle and joint pain by combining anti-inflammatory and soothing ingredients. Its topical spray provides targeted relief while helping reduce discomfort and improve movement.

Benefits may include:

• Helps relieve localized muscle and joint pain and soreness.
• Diclofenac helps reduce pain and inflammation in the treated area.
• Helps ease muscle tightness, spasms, and discomfort associated with minor strains and other musculoskeletal conditions.
• Menthol provides a cooling sensation, while methyl salicylate and turpentine oil provide warming sensations that can help reduce the awareness of pain.
• Systaflam Spray format allows convenient application directly to the affected area without extensive massage.
• Supports more comfortable movement and daily activities when used as directed.

Directions for Use

  • Use Systaflam Spray 3-4 times a day or as advised by the physician.
  • Shake well before each use and spray the contents from a distance of 5cm on the affected area.
  • Avoid contact of Systaflam Spray with your eyes, nose, and mouth. If contact occurs with these areas, rinse thoroughly with water.
  • For external use only.

How Systaflam Spray Works

Systaflam Spray contains Diclofenac, Mephenesin, Menthol, Turpentine Oil, and Methyl Salicylate. Diclofenac: It is a topical non-steroidal anti-inflammatory drug (NSAID) that blocks cyclooxygenase (COX) enzymes involved in producing prostaglandins. By reducing these chemicals, it helps decrease pain, swelling, and inflammation at the affected area. Mephenesin: It is a muscle relaxant that may help reduce muscle tightness and discomfort. In topical preparations, its exact local mechanism is not fully established, but it may contribute to the overall muscle-relaxing and soothing effects of the formulation. Menthol: It acts on cold-sensitive receptors in the skin, producing a cooling sensation that can temporarily change the perception of pain and provide soothing relief from localized discomfort. Turpentine Oil: It acts as a warming counter-irritant that stimulates sensory nerves in the skin and may increase local blood flow. This warming sensation can temporarily reduce the awareness of muscle and joint pain. Methyl Salicylate: It acts mainly as a topical counter-irritant and produces a warming sensation that can temporarily reduce the perception of localized muscle and joint pain. After absorption, it is converted to salicylate, which contributes to its pain-relieving effects.
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Alcohol

Consult your doctor

It is unknown whether it is safe to consume alcohol with Systaflam Spray. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Systaflam Spray can be used by breastfeeding mothers or not.

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Driving

Not applicable

Systaflam Spray does not impact your ability to drive or operate machinery.

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Liver

Consult your doctor

Limited information was available regarding the use of Systaflam Spray in patients with liver disease. If you have concerns about the use of Systaflam Spray in patients with liver disease, please consult your doctor.

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Kidney

Consult your doctor

Limited information was available regarding the use of Systaflam Spray in patients with kidney disease. If you have concerns about the use of Systaflam Spray in patients with kidney disease, please consult your doctor.

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Children

Caution

Systaflam Spray may not be recommended for children. Please consult the doctor.

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Heart

Consult your doctor

Limited information is available regarding the use of Systaflam Spray in patients with heart disease. Please consult your doctor before using Systaflam Spray if you have any heart problems.

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Geriatrics

Consult your doctor

Limited information is available on the use of Systaflam Spray in elderly patients. Please consult a doctor if you have any concerns about its use in elderly patients.

What if I have taken an overdose of Systaflam Spray

Because Systaflam Spray is applied to the skin, a serious systemic overdose is highly unlikely when used as directed. However, if Systaflam Spray is accidentally swallowed, or if it is applied to very large areas of the skin for an extended period, it may cause systemic side effects. If you suspect an overdose or if someone has swallowed Systaflam Spray, seek immediate medical attention or contact a local poison control center right away.

Diet & Lifestyle Advise

  • Stay Hydrated: Drinking adequate water throughout the day helps maintain muscle elasticity and reduces the frequency of painful muscle cramps.
  • Incorporate Gentle Movement: Engage in low-impact physical activities, such as stretching, walking, or swimming, to keep your joints flexible and prevent muscle atrophy.
  • Follow an Anti-inflammatory Diet: Focus on foods rich in omega-3 fatty acids, such as walnuts, chia seeds, and fatty fish, which can naturally help manage inflammation in the body.
  • Apply Controlled Cold or Heat: Use an ice pack for acute, sudden injuries to reduce swelling, and transition to gentle heat therapy for chronic muscle stiffness after the initial swelling subsides.
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How Soon It Starts Working

The time required for Systaflam Spray to start to work: Systaflam Spray ideally shows its action within 30 minutes after application. The time for which the effects of Systaflam Spray last: The effect of Systaflam Spray lasts for 4 to 6 hours.

Storage

• Store Systaflam Spray at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

What if you forget to take Systaflam Spray

If you forget to apply Systaflam Spray, use it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and resume your regular schedule. Do not apply a double amount of spray to make up for a missed application.

Drug Warnings

  • Do not cover or heat the treated area: Avoid tight bandages, wraps, heating pads, or other heat sources over the treated skin, as these may increase medicine absorption and the risk of side effects.
  • Avoid contact with sensitive areas: Do not spray Systaflam Spray near your eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse the area thoroughly with cool water.
  • Check the spray nozzle before use: Make sure the nozzle is clean and free of blockages before each use. Never insert pins, needles, or other sharp objects into the nozzle, as this may damage Systaflam Spray mechanism.
  • Avoid using other topical products: Do not apply other creams, gels, sprays, or medicated skin products to the same area at the same time unless specifically advised by your doctor.
  • Stop use if severe skin reactions occur: Stop using Systaflam Spray and wash the treated area gently with mild soap and water if you develop severe irritation, hives, or a painful rash. Seek medical advice if the reaction persists or worsens.
  • Protect the treated skin from sunlight: Avoid prolonged exposure to direct sunlight and strong sources of ultraviolet light on areas where Systaflam Spray has been applied. Use protective clothing or sunscreen when appropriate, and contact your doctor if you develop unusual redness, rash, or other skin reactions after sun exposure.
  • Do not apply to large areas: Do not use Systaflam Spray over large areas of the body unless specifically directed by your doctor. Applying excessive amounts or treating large areas may increase medicine absorption and the risk of side effects.

Drug-Drug Interactions

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  • Other NSAIDs (e.g., ibuprofen, naproxen, oral diclofenac): Using these medicines alongside the diclofenac-containing spray may increase the risk of stomach irritation, ulcers, bleeding, or other NSAID-related side effects.
  • Blood thinners (e.g., warfarin, apixaban): Taking these medicines with the diclofenac-containing spray may increase the risk of bruising or bleeding, particularly with prolonged use or application over large areas.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Systaflam Spray when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Systaflam Spray is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain.
Systaflam Spray combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain, which are responsible for causing pain and symptoms of inflammation, redness, and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps improve blood circulation and relieve pain. Turpentine Oil is a lubricant.
Avoid concomitant use of Systaflam Spray with other topical products such as cosmetics, sunscreens, lotions, moisturisers, insect-repellent creams, and other gels.
Please do not take any NSAID/painkiller medicines along with Systaflam Spray unless advised by the doctor, as it could increase the risk of ulceration, perforation, and bleeding in the stomach and intestine. Inform your doctor before using Systaflam Spray if you are taking any NSAIDs orally.
No, the use of Systaflam Spray is contraindicated on the broken or cut wound skin. It should be applied only topically on the uppermost skin surfaces (epidermis). Do not spray on open wounds.
Yes, Systaflam Spray is safe if used in the dose and duration exactly as recommended by the doctor.
Avoid contact of Systaflam Spray with the eyes, nose, or mouth. If accidental contact occurs, rinse it off thoroughly with water immediately. It is for external use only and should not be swallowed; in case of accidental ingestion, consult the doctor or contact a nearby poison control centre immediately.
Most people experience a cooling sensation within a few minutes of spraying Systaflam Spray, followed by a warming sensation that helps soothe deep muscle aches. The anti-inflammatory effect will build up with regular use over a few days. Inform your doctor if your pain does not improve after a week.
No, you should not apply a heating pad or any hot compress over the area treated with Systaflam Spray. The heat can excessively increase the absorption of the active ingredients, which increases the risk of severe skin irritation or chemical burns.
Systaflam Spray should be used during pregnancy only if specifically suggested by your healthcare provider. NSAID-containing products should generally be avoided in the third trimester as they can cause complications for the baby. Consult your doctor before using Systaflam Spray if you are pregnant or planning to become pregnant.
If Systaflam Spray gets into your eyes, mouth, or nose, rinse the area immediately with large amounts of cool, clean water. If burning, redness, or pain persists after rinsing, seek medical help right away. Inform your doctor if you experience any vision changes or persistent discomfort.
Systaflam Spray is generally not recommended for use in young children unless specifically advised and supervised by a pediatrician. Children's skin is more sensitive, and they may absorb the active ingredients more readily. Consult your doctor to determine if this product is safe for your child.
Use Systaflam Spray for the shortest period recommended by your doctor or stated on the product label. Continuous use beyond about 7 to 10 days should generally be reviewed by a healthcare professional, especially because it contains diclofenac. If your pain continues or worsens, seek medical advice rather than continuing Systaflam Spray on your own.

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Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - SYS0092
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