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Shpt 2.5 mcg Tablet contains Doxercalciferol, which belongs to the vitamin D analogue class of medications. It promotes the body's consumption of calcium from food or supplements and the management of parathyroid hormone synthesis. Thus, Doxercalciferol helps to treat secondary hyperparathyroidism in chronic renal disease patients. Common side effects of this medication are headache, dizziness, heartburn, sleep disorders, joint pain, and weight gain.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Neovae Biomedics Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Shpt 2.5 mcg Tablet

Shpt 2.5 mcg Tablet is a prescription medication used to manage overactive parathyroid glands (secondary hyperparathyroidism) in people with ongoing kidney disease. It helps control the levels of parathyroid hormone, which can otherwise cause severe bone and joint complications. By keeping this hormone in balance, the medicine supports overall bone health in patients with kidney impairment.

You should take Shpt 2.5 mcg Tablet consistently, exactly as your doctor directs, which may be daily or a few times a week depending on your laboratory results. This capsule can be taken with or without food, but keeping a regular schedule helps maintain steady levels in your body. Making dietary changes, such as limiting foods high in phosphorus, is often necessary to get the best results from this therapy.

While taking this medicine, you might experience mild side effects like headaches, nausea, or a metallic taste in your mouth. However, you must contact your healthcare provider immediately if you experience signs of high calcium levels, such as severe weakness, confusion, constant vomiting, or an irregular heartbeat.

Do not take this if you have naturally high levels of calcium or vitamin D in your blood, as this medication can raise these levels further. Before starting, tell your doctor if you have a history of heart disease or liver problems.

This medicine can interact with certain other drugs like mineral oil or antacids containing magnesium, which can block absorption or cause mineral imbalances. If you are pregnant, breastfeeding, or are an older adult, discuss your specific risks with your doctor before starting therapy.

Uses of Shpt 2.5 mcg Tablet

Your doctor may prescribe Shpt 2.5 mcg Tablet to treat the following condition and help maintain healthy bone mineral balance:

  • Secondary hyperparathyroidism (overactive parathyroid glands caused by kidney disease): Shpt 2.5 mcg Tablet helps lower high levels of parathyroid hormone in people with chronic kidney disease, including those receiving dialysis and some patients with advanced kidney disease who are not yet on dialysis. Treatment goals, dosing schedules, and monitoring frequency may differ between dialysis and non-dialysis patients. 

Key Benefits

Using Shpt 2.5 mcg Tablet as prescribed helps manage secondary hyperparathyroidism and protect your bones and blood vessels. Here are the key benefits you can expect:

  • Protects bone health: Shpt 2.5 mcg Tablet helps protect your skeletal system by keeping parathyroid hormone levels in a safe range. This helps prevent calcium from being lost from your bones, reducing the risk of bone pain, fractures, and bone deformities associated with kidney disease.
  • Supports healthy mineral balance: By managing your mineral levels, Shpt 2.5 mcg Tablet helps maintain the proper balance of calcium and phosphorus in the body.
  • Supports cardiovascular health: By managing your mineral levels, it also helps prevent calcium deposits from building up in vital organs, such as your blood vessels, heart, and lungs, which supports your long-term cardiovascular health.
Side effects of Shpt 2.5 mcg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Take Shpt 2.5 mcg Tablet with or without food or as advised by a doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Shpt 2.5 mcg Tablet Works

Shpt 2.5 mcg Tablet contains doxercalciferol, an inactive form of vitamin D that is converted by the liver into its active form after you take the capsule. Once activated, Shpt 2.5 mcg Tablet binds to specific vitamin D receptors in the body to help regulate parathyroid hormone production. It signals the parathyroid glands to reduce hormone release while helping maintain healthy calcium and phosphorus levels. This supports bone health and helps prevent complications associated with secondary hyperparathyroidism in people with chronic kidney disease.
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Alcohol

Caution

Consuming alcohol along with Shpt 2.5 mcg Tablet is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

Shpt 2.5 mcg Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. So, inform your doctor if you are pregnant and planning to become pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Shpt 2.5 mcg Tablet is not recommended for use in breastfeeding women unless necessary. Before taking this medicine, the risks and benefits should be discussed with the doctor. Your doctor may advise you to discontinue the medication or breastfeeding based on your medical condition.

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Driving

Caution

It is unknown whether Shpt 2.5 mcg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Caution should be exercised while using Shpt 2.5 mcg Tablet in patients with liver disease. Inform your doctor before receiving Shpt 2.5 mcg Tablet if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Care and close monitoring should be exercised when using this agent in patients with severe renal impairment or on dialysis. Inform your doctor before receiving Shpt 2.5 mcg Tablet if you have a history of kidney diseases/conditions.

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Children

Caution

The safety and efficacy of Shpt 2.5 mcg Tablet in pediatric patients have not been established.

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Heart

Caution

Shpt 2.5 mcg Tablet should be used cautiously if you have heart problems, especially irregular heartbeat or high calcium levels, as it may worsen these conditions. Your doctor will likely monitor your heart and calcium levels closely to ensure safe use.

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Geriatrics

Caution

Geriatric patients can take Shpt 2.5 mcg Tablet , but doctors usually start at a lower dose due to age-related changes in liver and heart function. Regular monitoring of calcium and parathyroid hormone levels is essential to avoid complications like hypercalcemia.

What if I have taken an overdose of Shpt 2.5 mcg Tablet

In case of an accidental overdose, seek emergency medical attention immediately. Symptoms of an overdose may include extreme nausea, weakness, severe headache, or confusion.

Diet & Lifestyle Advise

  • Follow a low-phosphorus diet: Follow a low-phosphorus diet as recommended by your renal dietitian, avoiding foods such as dark sodas, dairy products, nuts, beer, and processed meats.
  • Monitor your fluid intake: Keep a record of your daily fluid intake if your doctor has advised you to restrict fluids due to kidney disease.
  • Avoid extra vitamin D or calcium: Do not take over-the-counter vitamin D supplements or calcium-containing antacids unless specifically instructed by your healthcare provider.
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Have a query?

How Soon It Starts Working

The time required for Shpt 2.5 mcg Tablet to start to work: Shpt 2.5 mcg Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Shpt 2.5 mcg Tablet last: The duration of action for Shpt 2.5 mcg Tablet is unknown.

Storage

•Store Shpt 2.5 mcg Tablet capsules at 20°C to 25°C (68°F to 77°F) in the original container. • Keep the container tightly closed to protect the medicine from light and moisture.

What if you forget to take Shpt 2.5 mcg Tablet

If you miss a dose of Shpt 2.5 mcg Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Attend regular blood tests: Keep all your scheduled appointments for blood tests, as your doctor needs to monitor your calcium and phosphorus levels closely to keep your treatment safe.
  • Check before taking new medicines: Do not start any new medicines, including herbal remedies or mineral supplements, without asking your doctor first.
  • Watch for signs of high calcium: Be alert for early signs of high calcium, such as a metallic taste in your mouth, dry mouth, or muscle pain, and report them to your healthcare team promptly.
  • Understand why you need this medicine: Healthy kidneys normally help activate vitamin D, but chronic kidney disease reduces this process. Shpt 2.5 mcg Tablet helps restore vitamin D activity and support healthy calcium, phosphorus, and parathyroid hormone balance. 

Drug-Drug Interactions

verifiedApollotooltip
  • Phosphate binders or calcium supplements: May raise calcium levels in your blood too high when taken alongside Shpt 2.5 mcg Tablet .
  • Magnesium-containing antacids: Can lead to high magnesium levels in your blood, which can be dangerous for patients with kidney problems.
  • Thiazide diuretics (water pills): May increase the risk of developing dangerously high calcium levels in the blood.
  • Phenobarbital or other seizure medications: May reduce the effectiveness of Shpt 2.5 mcg Tablet by affecting how your liver processes it.

Drug-Drug Interactions

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How does the drug interact with Shpt 2.5 mcg Tablet:
Co-administration of Shpt 2.5 mcg Tablet and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Shpt 2.5 mcg Tablet with Calcitriol can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Shpt 2.5 mcg Tablet:
Cholecalciferol and Shpt 2.5 mcg Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Shpt 2.5 mcg Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Shpt 2.5 mcg Tablet:
Coadministration of Shpt 2.5 mcg Tablet with sulfasalazine can increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Shpt 2.5 mcg Tablet and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Shpt 2.5 mcg Tablet when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[VITAMINS]

FAQs

Shpt 2.5 mcg Tablet contains Doxercalciferol. It promotes the body's consumption of calcium from food or supplements, as well as the management of parathyroid hormone synthesis.
Parathyroid hormone is secreted by four parathyroid glands, which are tiny glands in the neck positioned behind the thyroid gland.
Secondary hyperparathyroidism can cause bone disease. It can also cause calcium to build up in tissues and organs such as the heart and blood vessels.
The parathyroid glands generate parathyroid hormone, which is important in regulating calcium levels in the blood. Precise calcium levels are critical in the human body since even minor alterations can cause muscular and nerve issues.
Yes, you can take Shpt 2.5 mcg Tablet with or without food, but it is best to be consistent with how you take it. Talk to your doctor or pharmacist if you experience stomach upset.
This medicine affects calcium, phosphorus, and parathyroid hormone levels. Regular blood tests help your doctor ensure the dose is safe and working correctly. Talk to your doctor if you have questions about your lab results.
A metallic taste can be an early sign of elevated calcium levels in your blood. If you notice this, contact your doctor or pharmacist promptly to check your blood mineral levels.
You should avoid taking any extra vitamin D or calcium supplements unless your doctor explicitly tells you to do so, as this can lead to dangerously high mineral levels. Talk to your doctor before starting any new supplement.
The safety of this medication during pregnancy is not fully established. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the benefits and risks.
Some antacids contain magnesium or calcium, which can interact badly with this medicine and cause mineral imbalances. Always consult your pharmacist or doctor before taking any antacids.
Early signs of high calcium include headache, weakness, dry mouth, nausea, constipation, or muscle pain. If you experience these symptoms, contact your doctor immediately. Talk to your doctor if you have any concerns.
Many people with chronic kidney disease need Shpt 2.5 mcg Tablet for a long period because secondary hyperparathyroidism is often a chronic condition. Your doctor will review your blood test results regularly and may adjust, pause, or continue treatment depending on your calcium, phosphorus, and parathyroid hormone levels.
Healthy kidneys help activate vitamin D, which is important for controlling calcium, phosphorus, and parathyroid hormone levels. In chronic kidney disease, this activation process is reduced, so the body may not be able to use vitamin D normally. Shpt 2.5 mcg Tablet is prescribed to help correct this problem and reduce overactivity of the parathyroid glands caused by kidney disease.

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Country of origin

India

Manufacturer/Marketer address

Office No:- 305, Tf, Mahalakshmi Tower, Sector 4, Vaishali, Ghaziabad, U.P- 201010 Office No:- +91 120-4248888
Other Info - SHP0001
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