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Setfrac Plus Tablet is a combination medicine primarily used to treat nutritional deficiencies, low calcium levels (hypocalcaemia), osteoporosis, fractured bones, and joint pain. This medicine works by increasing the calcium and vitamin D levels in the body, thus providing essential nutrients necessary for bone formation and maintenance. Common side effects include headache, intestinal gas or belching, dry mouth, and diarrhoea.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CALCIUM-250MG+CHOLECALCIFEROL-10MCG+CISSUS QUADRANGULARIS-500MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Setfrac Plus Tablet

Setfrac Plus Tablet is a medicine helper formulated to support bone recovery, enhance bone strength, and manage joint-related issues. It is commonly suggested to help heal fractures and manage conditions where bones become weak or brittle. Your doctor may recommend this to ensure your skeletal system receives the critical nutritional support it needs during recovery.

For the best results, you must take Setfrac Plus Tablet regularly and consistently at the same times each day. It is highly recommended to take this medication with food, as this significantly improves how well your body absorbs its key bone-building ingredients. Combining this treatment with a balanced diet rich in minerals and regular, low-impact physical activity can further improve your bone recovery outcomes.

While taking Setfrac Plus Tablet, some individuals may experience mild side effects like an upset stomach or constipation. If you experience severe symptoms, such as extreme fatigue, persistent vomiting, or signs of an allergic reaction, stop taking the medication and consult your doctor immediately. Always keep your healthcare provider informed of any unusual changes you notice while using this product.

Do not take this if you have been diagnosed with high calcium levels in your blood or urine, or if you have severe kidney problems. It is crucial to talk to your doctor before starting Setfrac Plus Tablet if you have a history of kidney stones or thyroid disorders. Your doctor will help determine if this is the safest option for your skeletal health.

Certain medicines, such as specific antibiotics and iron supplements, can interfere with how your body absorbs Setfrac Plus Tablet, so they should be taken at different times of the day. If you are pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting this treatment to ensure the dosage is safe and appropriate for your specific needs.

Uses of Setfrac Plus Tablet

Your doctor may prescribe Setfrac Plus Tablet for several key therapeutic reasons:

  • Bone fracture healing: Setfrac Plus Tablet helps speed up the natural repair process of broken bones and strengthens the surrounding skeletal tissue during recovery.
  • Osteoporosis: This medicine helps manage and prevent weak, brittle bones by restoring lost mineral density and improving overall bone strength.
  • Joint and bone weakness: It supports structural joint integrity, helping to reduce pain and improve mobility in weak or degraded joints.
     

Key Benefits

Setfrac Plus Tablet is composed of Cissus quadrangularis (a herbal supplement), Calcium (mineral), and Cholecalciferol (Vitamin D3). Setfrac Plus Tablet is used to support bone health and effectively treats various conditions caused by low calcium levels in the body. Cissus quadrangularis is a medicinal plant and an antioxidant. It is used in reducing bone loss, regulating diabetes, high cholesterol, allergies, and asthma. Calcium is a mineral used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Cholecalciferol helps maintain blood calcium and phosphorus levels and mineralization of bone. It aids in calcium absorption enabling bone growth and repair. It further prevents cartilage degeneration.

Directions for Use

  • Setfrac Plus Tablet can be taken with or without food, or as directed by your doctor.
  • The daily dose of Setfrac Plus Tablet depends on individual health needs and medical conditions. Follow your doctor's instructions regarding dosage and timing for better effectiveness.
  • Swallow Setfrac Plus Tablet as a whole with a glass of water.
  • Do not crush, chew, or break Setfrac Plus Tablet.

How Setfrac Plus Tablet Works

Setfrac Plus Tablet is a combination medicine that utilises three active components to rebuild and protect your bones: The first component is a natural herbal extract known as Cissus quadrangularis. This herb works by stimulating the activity of osteoblasts, which are the specialised cells in your body responsible for building new bone tissue. It also helps control joint pain and swelling. The second component is calcium, which serves as the primary structural building block your body needs to construct and maintain a strong, dense skeleton. The third component is cholecalciferol (Vitamin D3). Cholecalciferol acts as a crucial helper that enables your gut to efficiently absorb calcium. Without sufficient Vitamin D3, your body cannot properly utilise the calcium you ingest, meaning it cannot reach your bones where it is needed most.
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit/avoid the alcohol intake while using Setfrac Plus Tablet.

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Pregnancy

Caution

Please consult your doctor before taking Setfrac Plus Tablet if you are pregnant or planning to conceive. Setfrac Plus Tablet should be used during pregnancy only when recommended by the doctor.

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Breast Feeding

Caution

Please consult your doctor before taking Setfrac Plus Tablet if you are breastfeeding. Your doctor will weigh the potential risks and benefits before recommending Setfrac Plus Tablet.

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Driving

Safe

Setfrac Plus Tablet usually does not interfere with your driving ability.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Setfrac Plus Tablet.

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Kidney

Caution

It is advised to seek doctor advice before starting Setfrac Plus Tablet if you have kidney diseases like kidney stones or undergoing dialysis.

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Children

Caution

Please consult your doctor before giving Setfrac Plus Tablet to children. Your doctor will decide if Setfrac Plus Tablet can be given to your child or not.

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Heart

Consult your doctor

Inform your doctor if you have a history of heart disease. Your doctor will recommend only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Setfrac Plus Tablet should be given to elderly patients only if recommended by a doctor. If you have any concerns about using Setfrac Plus Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Setfrac Plus Tablet

If you take more than your suggested dose and experience severe symptoms like extreme stomach pain, persistent vomiting, or confusion, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat a bone-healthy diet: Incorporate calcium-rich foods like dairy products, green leafy vegetables, tofu, and fortified cereals into your meals.
  • Get safe physical activity: Engage in low-impact, weight-bearing exercises such as walking or light strength training, as approved by your doctor, to stimulate bone healing.
  • Limit caffeine and sodas: High intake of caffeine and carbonated beverages can reduce how well your body absorbs calcium.
  • Avoid smoking and limit alcohol: Tobacco use and excessive alcohol consumption interfere with bone-building cells and slow down the healing of fractures.

Health Queries

After my left humerus plating surgery, I was advised to take Setfrac Plus Tablet, but it is unavailable. What is a suitable substitute?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Since Setfrac Plus isn't presently available, your doctor can recommend a comparable bone-support supplement that contains the same essential nutrients. As an example, consider Radifrac Plus Tablet, which also contains calcium and other bone-healthy elements. However, you should check with your doctor before switching to make sure the dosage and formulation are appropriate for you.
health query

Have a query?

How Soon It Starts Working

The time required for Setfrac Plus Tablet to start to work: Setfrac Plus Tablet starts to show its action within 1 to 2 hours of administration. The time for which the effects of Setfrac Plus Tablet last: Setfrac Plus Tablet effect lasts for 12 to 24 hours.

Storage

•Store Setfrac Plus Tablet at room temperature, ideally between 15°C and 30°C. •Keep the tablets in their original packaging to protect them from direct sunlight, heat, and moisture. Do not store them in the bathroom.

What if you forget to take Setfrac Plus Tablet

If you miss a dose of Setfrac Plus Tablet, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Inspect the package before use; do not take the medication if the blister pack is torn or if the tablets appear discoloured or damaged.
  • Always inform your surgeon, dentist, or any other healthcare provider that you are taking Setfrac Plus Tablet before undergoing any medical procedures.
  • If you take thyroid medicines or oral iron supplements, make sure to take them at least 2 to 4 hours before or after taking Setfrac Plus Tablet to prevent absorption issues.
  • Your doctor may request routine blood and kidney tests if you need to take this medicine for an extended period.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Antibiotics (Tetracyclines and Quinolones): Setfrac Plus Tablet can significantly reduce the absorption and effectiveness of these antibiotics. Space these medications at least 2 hours apart.
  • Thyroid Medications (Levothyroxine): Calcium can block the absorption of thyroid hormones. Take these medications several hours apart.
  • Thiazide Diuretics (Water pills): Taking these alongside Setfrac Plus Tablet may increase the risk of developing excessively high calcium levels in your blood.
Calcium citrate + ColecalciferolCalcifediol
Severe
Calcium citrate + ColecalciferolDihydrotachysterol
Severe

Drug-Drug Interactions

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Calcium citrate + ColecalciferolCalcifediol
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Calcium citrate + ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Calcium citrate + ColecalciferolErgocalciferol
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Calcium citrate + ColecalciferolDihydroxialumini sodium carbonate
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Co-administration of Calcium citrate with Dihydroxyaluminum sodium carbonate may increase the effects of Dihydroxyaluminum sodium carbonate, which could result in too high aluminum blood levels.

How to manage the interaction:
Although there is an interaction, Calcium citrate can be used with Dihydroxyaluminum sodium carbonate if prescribed by the doctor. However, maintain a gap of 2-3 hours between both medicines. Do not discontinue the medication without consulting a doctor.
Calcium citrate + ColecalciferolDoxercalciferol
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Calcium citrate + ColecalciferolAluminium hydroxide
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Co-administration of Calcium citrate with Aluminum hydroxide may increase the effects of aluminum hydroxide, which could result in too high aluminum blood levels.

How to manage the interaction:
Although there is an interaction, calcium citrate can be used with aluminum hydroxide if prescribed by the doctor. However, maintain a gap of 2-3 hours between both medicines. Do not discontinue the medication without a doctor's advice.
Calcium citrate + ColecalciferolDolutegravir
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Co-administration of Dolutegravir with Calcium citrate can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although there is an interaction, Calcium citrate can be used with Dolutegravir if prescribed by the doctor. However, take dolutegravir at least two hours before or six hours after calcium citrate. Do not discontinue the medication without consulting a doctor.
Calcium citrate + ColecalciferolParicalcitol
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Calcium citrate + ColecalciferolCalcitriol
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Calcium citrate + ColecalciferolSucralfate
Severe
How does the drug interact with Setfrac Plus Tablet 15`s:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-fibre and oxalic acid foods: Foods like spinach, rhubarb, and whole grains can bind to calcium in your digestive tract, lowering the amount your body absorbs if eaten at the same time.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Setfrac Plus Tablet belongs to the class of nutritional supplements, primarily used to support bone health and effectively treats various conditions caused by low calcium levels in the body. It is used as a supplement in osteoporosis (weak and brittle bones), rickets or osteomalacia (softening or deforming of bones due to lack of calcium), osteopenia (low bone mass), fractured bones, and joint pain.
Setfrac Plus Tablet is a dietary supplement that supports bone health and prevents various bone-related disorders like osteoporosis, osteomalacia, and osteopenia. It also ensures the healing of fractured bones and has anti-inflammatory, analgesic, and antioxidant properties.
Setfrac Plus Tablet contains calcium and increases low levels of calcium in the body. Hence it is not advised to use Setfrac Plus Tablet during hypercalcaemia since it causes the overdose of calcium leading to kidney stones and other effects.
Antacids may increase the absorption of Calcium from Setfrac Plus Tablet. Hence, taking Setfrac Plus Tablet two hours before or four hours after taking antacids is advised.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
It is highly recommended to take Setfrac Plus Tablet with food. Taking it with a meal helps your body absorb the calcium and Vitamin D3 much more efficiently and reduces the likelihood of experiencing an upset stomach. Talk to your doctor if you have questions about your routine.
If you are pregnant or planning to become pregnant, you should consult your doctor before taking Setfrac Plus Tablet. Your doctor will evaluate if this specific formulation and dosage are appropriate for your nutritional needs during pregnancy.
If you have a history of kidney stones, you must exercise caution. Taking calcium supplements can sometimes increase the risk of forming new stones. Talk to your doctor, who may want to monitor your calcium levels closely or adjust your intake.
Vitamin D3 is essential because it acts as the key that unlocks your digestive system's ability to absorb calcium. Without adequate Vitamin D3, much of the calcium you consume would pass through your body unused rather than reaching your bones. Talk to your doctor or pharmacist for more details.
Yes, it can. Many multivitamins already contain calcium or Vitamin D3. Taking them together might lead to an accidental intake of too much calcium or Vitamin D. Talk to your doctor or pharmacist to review all your supplements before taking them together.
Constipation is a common side effect of calcium-containing supplements. To manage this, try to drink plenty of water throughout the day and eat foods high in fibre, such as fruits and vegetables. If the constipation persists or becomes painful, talk to your doctor.
It is best to take Setfrac Plus Tablet with plain water. Caffeine found in tea and coffee can interfere with how well your body absorbs calcium, reducing the effectiveness of the medicine. Talk to your doctor for personalised dietary advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - SET0197

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