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compositionComposition:PILOCARPINE-2%W/V
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Pilo 2 Eye Drop is used to treat open-angle glaucoma, ocular hypertension, and prevent postoperative elevated intraocular pressure associated with laser surgery and the induction of miosis (constriction of the pupil). It contains Pilocarpine, which works by draining the excess fluid from the eye, thereby reducing pressure. In some cases, this medicine may cause side effects such as headache/brow ache, irritation, pain, blurred vision, and/or visual impairment. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PILOCARPINE-2%W/V

Manufacturer/Marketer :

Aurolab

Consume Type :

Ophthalmic

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Pilo 2 Eye Drop

Pilo 2 Eye Drop is a prescription ophthalmic solution used to lower high pressure inside the eyes. It is primarily prescribed for people with open-angle glaucoma or ocular hypertension, conditions that can damage the optic nerves if left untreated. It may also be used to constrict the pupil before or after certain eye procedures.

To get the best results, you must use Pilo 2 Eye Drop consistently every day exactly as prescribed by your doctor. Since these are eye drops, they can be used without regard to meals, but establishing a regular daily schedule helps you remember your doses. Incorporating a heart-healthy diet, staying active, and reducing caffeine intake can also support your overall eye health.

While using Pilo 2 Eye Drop, you may experience temporary side effects like mild brow ache, headache, or blurry vision, especially in dim light. If you notice severe symptoms such as sudden changes in your vision, flashes of light, or signs of an allergic reaction, contact your doctor immediately.

Do not use Pilo 2 Eye Drop if you have active eye inflammation, such as iritis or uveitis, where pupil constriction should be avoided. Before starting this medication, tell your doctor if you have a history of retinal problems, asthma, or heart conditions.

Inform your doctor of all other eye medications you use, as some drops can counteract Pilo 2 Eye Drop or increase your risk of side effects. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Pilo 2 Eye Drop

Pilo 2 Eye Drop is used to treat high pressure inside the eyes. The detailed uses of Pilo 2 Eye Drop are as follows:

  • Glaucoma and high eye pressure: Pilo 2 Eye Drop helps reduce fluid pressure inside the eyes, preventing damage to the optic nerve and preserving your sight.
  • Pupil constriction (Miosis): It is used to temporarily shrink the pupil before or after certain eye surgeries or diagnostic eye examinations.

Key Benefits

Pilo 2 Eye Drop provides reliable and daily support to help you manage your health. This medicine brings several key health benefits:

  • Protects your long-term vision: By consistently lowering the fluid pressure within your eyes, Pilo 2 Eye Drop prevents gradual, permanent damage to your optic nerve, helping you maintain your existing sight.
  • Relieves eye pressure quickly: The drops work rapidly to ease elevated intraocular pressure, providing reliable control that helps you manage chronic eye conditions with confidence.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
  • Do not touch the tip of the dropper to prevent contamination.

How Pilo 2 Eye Drop Works

Pilo 2 Eye Drop contains pilocarpine, which activates specific receptors (muscarinic receptors) in the eye muscles, the same receptors normally triggered by the body's own nerve signals. When you use the drops, the medication stimulates the iris sphincter muscle, causing your pupil to shrink (constrict). At the same time, it causes the ciliary muscle in the eye to contract. This contraction opens up the eye's natural drainage pathways, allowing excess fluid (aqueous humour) to flow out more easily. By improving this fluid drainage, Pilo 2 Eye Drop successfully lowers the pressure inside your eye, protecting your delicate optic nerve from damage.
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Alcohol

Unsafe

Pilo 2 Eye Drop may interact with alcohol, so it is advised not to drink alcohol while using this medicine.

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Pregnancy

Consult your doctor

Pregnancy category C. Pilo 2 Eye Drop should be used in pregnant women only if clinically needed, when the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Pilo 2 Eye Drop should be used in breastfeeding mothers only if clinically needed when the benefits outweigh the risks.

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Driving

Caution

Pilo 2 Eye Drop may cause temporary blurred vision, so do not drive or operate heavy machinery until your vision is clear.

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Liver

Safe if prescribed

Pilo 2 Eye Drop is probably safe when used in patients with liver diseases. In case you experience any difficulty, discuss it with your doctor.

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Kidney

Safe if prescribed

Pilo 2 Eye Drop is probably safe when used in patients with kidney diseases. In case you experience any difficulty, discuss it with your doctor.

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Children

Caution

Pilo 2 Eye Drop should be used in children and adolescents under 18 years of age only if clinically needed when the benefits outweigh the risks. Your doctor may have to adjust the dose.

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Heart

Caution

Pilo 2 Eye Drop should be used with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart conditions before using it.

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Geriatrics

Caution

Pilo 2 Eye Drop should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Pilo 2 Eye Drop.

What if I have taken an overdose of Pilo 2 Eye Drop

If you accidentally instil too many drops, or if the medication is swallowed, seek immediate medical attention right away.

Diet & Lifestyle Advise

  • Sleep with your head raised: Keep your head elevated slightly with an extra pillow while sleeping to help reduce eye pressure overnight.
  • Limit caffeine: Limit your intake of caffeine, as drinking large amounts of caffeinated beverages in a short period can temporarily raise pressure inside your eyes.
  • Stay physically active: Engage in moderate, regular exercise like walking, which may help lower eye pressure, but avoid exercises that involve head-down positions (such as certain yoga poses).
  • Protect your eyes: Protect your eyes from bright light and injury by wearing sunglasses when outdoors, especially since your pupils may react differently to light while using this medication.
health query

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How Soon It Starts Working

The time required for Pilo 2 Eye Drop to start to work: Pilo 2 Eye Drop ideally shows its action within 10 to 30 minutes after administration.

The time for which the effects of Pilo 2 Eye Drop last: The effect of Pilo 2 Eye Drop lasts for 24 hours.

Storage

• Store Pilo 2 Eye Drop eye drops according to the manufacturer's packaging instructions, generally at room temperature between 15°C and 25°C (59°F to 77°F) or in refrigeration before opening.

What if you forget to take Pilo 2 Eye Drop

If you miss a dose of Pilo 2 Eye Drop, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your routine. Do not apply double drops to make up for a missed dose.

Drug Warnings

  • Inspect the Solution Before Use: Do not use the eye drops if the liquid appears cloudy, discoloured, or contains visible particles.
  • Use Caution in Low-Light Conditions: Pilo 2 Eye Drop may temporarily affect your ability to see clearly in dim light or at night. Avoid driving or operating machinery until your vision has returned to normal.
  • Remove Contact Lenses Before Use: If you wear soft contact lenses, remove them before applying Pilo 2 Eye Drop and wait at least 15 minutes before reinserting them, unless your doctor advises otherwise.
  • Avoid Contaminating the Dropper: Never allow the dropper tip to touch your eye, fingers, or any other surface to help keep the solution sterile.
  • Space Out Other Eye Medicines: If you are using other ophthalmic medications, wait at least 5 to 10 minutes between applications, or follow your doctor's instructions.

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Anticholinergic eye drops: Medicines such as atropine can cancel out the effects of both medications.
  • Other eye drops: Pilo 2 Eye Drop, designed to lower eye pressure, can increase the risk of side effects or excessive pressure lowering with other drops.

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verifiedApollotooltip

No clinically significant food interactions are known with Pilo 2 Eye Drop when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

FAQs

Pilo 2 Eye Drop is used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is used to manage acute angle-closure glaucoma, the prevention of postoperative elevated IOP associated with laser surgery, and the induction of miosis (excessive constriction of the pupil of the eye).
Pilo 2 Eye Drop contains Pilocarpine. It reduces the eye's fluid production and increases the natural flow of fluid from inside the eye into the bloodstream. These effects help to decrease the pressure and swelling inside the eye. It helps to improve vision and prevent the complications of open-angle glaucoma or ocular hypertension.
Yes. If you are using more than one eye medication, wait at least 5–10 minutes between eye drops (or as directed by your doctor) to prevent one medication from washing out the other. Follow your doctor's instructions for the order and timing of each medication.
Please do not stop taking Pilo 2 Eye Drop even if you feel better, as this may worsen your condition. For the best advice, consult your doctor and do as recommended.
Yes, Pilo 2 Eye Drop is good for glaucoma as it helps treat high pressure inside the eye due to glaucoma. Talk to the doctor if you have any concerns.
Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
It is not known if Pilo 2 Eye Drop causes the growth of eyelashes. However, it is used to lower high pressure in the eye and is not indicated for eyelash growth. Consult the doctor if you have any concerns.
The common side-effects of Pilo 2 Eye Drop are headache/brow ache, accommodative change, eye irritation, eye pain, blurred vision, and/or visual impairment. Most of these side effects of Pilo 2 Eye Drop do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, you should not apply the drops while wearing soft contact lenses. The preservatives in the solution can absorb into the lenses and discolour them. Remove your lenses before instilling the drops and wait at least 15 minutes before putting them back in. Talk to your doctor or pharmacist if you have questions about lens care.
This medication causes your pupils to shrink, which limits the amount of light that enters your eyes. This can temporarily reduce your ability to see clearly in dim environments or at night. Avoid driving or operating machinery in low light while using this medicine, and talk to your doctor if you experience severe vision changes.
Yes, mild headaches or aching around the brow area are common side effects, especially during the first few weeks of treatment as your eye muscles adjust. These symptoms usually improve over time. If your headaches are severe or do not go away, talk to your doctor.
Swallowing this medication can lead to serious systemic side effects like severe sweating, nausea, slow heart rate, or breathing difficulties. If anyone accidentally swallows the eye drops, seek emergency medical care. Talk to your doctor or pharmacist for further guidance.
Yes, but you must space them out. If your doctor has prescribed multiple eye drops, wait at least 5 to 10 minutes between applying each medication to prevent the first drop from being washed out by the second. Talk to your doctor or pharmacist to establish the best daily schedule.
The safety of this medication during pregnancy is not fully established, as systemic absorption could potentially affect the baby. It should only be used if the potential benefits outweigh the risks. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 200890S001Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.3398 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Pilocarpine Ophthalmic Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Pilocarpine hydrochloride [Product Information]. 2025. [Accessed on 03 Apr. 2025]Check here
  5. EMA.SmPC. Pilocarpine. [[Accessed on 18.Feb].2020]Check here
  6. Mayoclinic. Pilocarpine. [[Accessed on 18.Feb].2020]Check here
  7. Victoria Panarese; Majid Moshirfar. Pilocarpine. NIH National Library of Medicine, National center for biotechnology information. StatPearls [Internet]. December 2021. [Accessed on 23rd June 2022].Check here

Country of origin

India
Other Info - PI99901
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