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  3. P-Cool Cream 20 gm

P-Cool Cream 20 gm, Pack of 1 CREAM
P-Cool Cream 20 gm, Pack of 1 CREAM
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
P-Cool Cream is used to treat pain and bleeding associated with anal fissures and haemorrhoids (piles). It decreases swelling by shrinking the blood vessels and reduces the sensation of pain. In some cases, this medicine may cause side effects such as burning sensation, irritation, itching and redness at the application site. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

CALAMINE-5%W/W + LIDOCAINE-3%W/W + PHENYLEPHRINE-0.1%W/W

Manufacturer/Marketer :

Group Pharmaceuticals Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

About P-Cool Cream

P-Cool Cream is a combination medicine used to treat pain and bleeding associated with anal fissures and haemorrhoids (piles). An anal fissure is a small tear in the mucosa that lines the anus. Haemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause pain, discomfort, and bleeding.
 
P-Cool Cream is a combination of three drugs, namely: Calamine (anti-pruritic), phenylephrine (sympathomimetic agent), and lidocaine (local anaesthetic). Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain. 
 
In some cases, you may experience certain common side-effects such as burning sensation, irritation, itching and redness at the application site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Let your doctor know if you are using prescription/nonprescription drugs and herbal products before starting P-Cool Cream. If you are known to be allergic to any of the components in P-Cool Cream, please inform your doctor. Consult your doctor before using P-Cool Cream if you are pregnant or breastfeeding. P-Cool Cream should not be used in children unless prescribed by a doctor. 

Uses of P-Cool Cream

Treatment of Piles and anal fissures

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Check the label for directions and use it as advised by the doctor. Take the prescribed amount of P-Cool Cream onto the applicator and apply it to the rectal area.• Wash your hands before and after use.

Medicinal Benefits

P-Cool Cream is a combination of three drugs, namely: Calamine, phenylephrine, and lidocaine. P-Cool Cream is used to treat pain and bleeding associated with anal fissures, external or internal haemorrhoids (piles), post-haemorrhoidectomy pain (pain after operation done to remove piles), and minor degrees of proctitis (inflammation of the rectum). Calamine has antiseptic and anti-pruritic properties. Phenylephrine is a sympathomimetic agent which decreases swelling by shrinking the blood vessels in the affected area. Lidocaine is a local anaesthetic that blocks the pain signals from the nerves to the brain, thereby decreasing the pain sensation.

How P-Cool Cream Works

P-Cool Cream is a combination of three drugs, namely: Calamine (anti-pruritic), phenylephrine (sympathomimetic agent), and lidocaine (local anaesthetic). Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain.

Storage

Keep P-Cool Cream out of reach and sight of children.

What if I have taken an overdose of P-Cool Cream

Use P-Cool Cream only as suggested by the physician. Though overdose is unlikely due to low systemic absorption, it is advised to avoid exceeding the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not use P-Cool Cream if you are allergic to any of its components. Inform your doctor if you have high blood pressure, diabetes, thyroid problems, porphyria, fits, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are using prescription/nonprescription drugs or herbal products before starting P-Cool Cream.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat fiber-rich food and drink plenty of fluids. This helps to keep the stools soft.

  • A warm bath helps in easing pain and itching.

  • Keep your bottom dry and clean.

  • Regular exercise is recommended.

  • Avoid or limit alcohol and caffeinated products to prevent constipation.

  • Empty your bowels whenever your body tells you to.

  • Avoid pushing too hard while pooping as it can cause tearing of tissues.

  • Include vegetables, fruits, and whole wheat grains in your diet.

Habit Forming

No

Therapeutic Class

ANORECTAL PREPARATIONS
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Alcohol

Caution

It is not known whether P-Cool Cream interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether P-Cool Cream can be used by breastfeeding mothers or not.

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Driving

Safe if prescribed

P-Cool Cream does not affect your ability to drive.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of P-Cool Cream in patients with kidney impairment.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of P-Cool Cream in children.

Have a query?

FAQs

P-Cool Cream is used to treat pain and bleeding associated with anal fissures and haemorrhoids (piles).

P-Cool Cream contains calamine, phenylephrine and lidocaine. Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain.

P-Cool Cream should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using P-Cool Cream for a week, consult your doctor, he/she may prescribe you an alternate medicine.

No, P-Cool Cream should not be used on the face or any other body parts. It is intended to treat pain and bleeding in case of piles and anal fissures.

The symptoms of anal fissures and piles are similar. However, an anal fissure is a small tear in the mucosa that lines the anus, whereas piles are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain, and bleeding.

To treat your condition effectually, continue using P-Cool Cream for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while using P-Cool Cream.

Gently clean and dry the affected area. Use the applicator to apply the prescribed amount of medication to the rectal area.

The side effects of P-Cool Cream include irritation, redness, itching and burning sensation. Consult the doctor if any of these symptoms persist or worsen.

Avoid contact with eyes, nose or mucous membrane. If P-Cool Cream accidentally comes into contact with your eyes, nose, or mouth, rinse it off thoroughly with plenty of water. Be sure to wash your hands before and after using P-Cool Cream.

Do not use P-Cool Cream if you are allergic to any of its ingredients. Avoid exceeding the recommended dose and use it as advised by the doctor.

P-Cool Cream should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

No. 159- B, 22nd Cross Street PIPDIC INDUSTRIAL ESTATE, PIPDIC Industrial Estate,, Mottoupalayam, Pondicherry-605009, India
Other Info - PCO0001

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:52 AM IST

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Reference

  1. https://www.drugs.com/mtm/calamine-topical.html
  2. https://www.drugs.com/mtm/phenylephrine-rectal.html
  3. https://www.nhs.uk/medicines/lidocaine-for-piles-and-itchy-bottom/

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