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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Osteokit is used to treat osteoporosis (weak and brittle bones). It provides essential nutrients to maintain bone health, increases calcium levels, reverses bone loss and increases bone mass. In some cases, this medicine may cause side effects such as headache, indigestion, heartburn, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Osteokit

Osteokit is a combination medicine primarily used to treat osteoporosis (weak and brittle bones). Osteoporosis is a bone disease that makes the bones weak and brittle by decreasing bone density. Symptoms include backache, easily breaking bones, and hunched or stooped posture.

Osteokit is a combination of Calcium (mineral), Calcitriol (Vitamin D3), Ibandronic acid (biphosphonate), and Zinc. Calcium and Zinc are minerals that provide essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 that raises Vitamin D levels and increases calcium levels in the blood. Ibandronic acid is a bisphosphonate that reverses bone loss and increases bone mass.

Your doctor will decide the dosage based on your medical condition. In some cases, Osteokit can cause side effects like bone/muscle pain, muscle cramps, stiffness in joints, headache, back pain, indigestion, heartburn, and diarrhea. Most of these side effects of Osteokit do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor. 

Do not stop or take Osteokit on your own unless the doctor has prescribed it for you. Please tell your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history to the doctor in advance if you have heart/kidney/liver diseases, kidney stones, and ulcers. Ibandronic acid is Osteokit is not recommended for pregnant or breastfeeding women. Osteokit is not recommended for children and adolescents below 18 years.

Uses of Osteokit

Treatment of Osteoporosis.

Directions for Use

• Osteokit can be taken with or without food as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Osteokit as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Osteokit is used to treat osteoporosis (weak and brittle bones). Osteokit consists of Calcium, Zinc, Calcitriol (Vitamin D3), and Ibandronic acid. Calcium and Zinc are minerals that provide essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Ibandronic acid belongs to the class of bisphosphonates. It reverses bone loss and increases bone mass. It works by inhibiting the action of osteoclasts (a bone cell that breaks down bone tissue), thus helping in the reduction of fractures.

How Osteokit Works

Osteokit is a combination of Calcium (mineral), Calcitriol (Vitamin D3), Ibandronic acid (biphosphonate), and Zinc. Calcium and Zinc are minerals that provide essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 that raises Vitamin D levels and increases calcium levels in the blood. Ibandronic acid is a bisphosphonate that reverses bone loss and increases bone mass.

Storage

Keep out of sight and reach of children.
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What if I have taken an overdose of Osteokit

Take Osteokit only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not lie down immediately after you take Osteokit and wait for at least 60 minutes. Let your doctor know if you are allergic to Osteokit or its inactive components. Osteokit is not recommended if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history to the doctor if you have any heart/kidney/liver diseases, kidney stones, ulcers, swallowing or digestive problems, and inflammation of the gut. Osteokit is not recommended during pregnancy and breastfeeding since it contains Ibandronic acid. It is advised to limit alcohol consumption since it can affect calcium absorption. Osteokit is not recommended for children and adolescents below 18 years.

Drug-Drug Interactions

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CalcitriolParicalcitol
Severe

Drug-Drug Interactions

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How does the drug interact with Osteokit:
Co-administration of Osteokit with Carbamazepine may decrease the effects of Osteokit.

How to manage the interaction:
Although there is an interaction, Osteokit can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolParicalcitol
Severe
How does the drug interact with Osteokit:
Co-administration of Paricalcitol and Osteokit are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Osteokit can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Osteokit:
Co-administration of Ergocalciferol and Osteokit are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Osteokit can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Osteokit:
Co-administration of Rifapentine with Osteokit may decrease the effects of Osteokit.

How to manage the interaction:
Although there is an interaction, Osteokit can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Osteokit:
Co-administration of Calcifediol and Osteokit are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Osteokit can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Osteokit:
Co-administration of Metolazone with Osteokit can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Osteokit can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Osteokit:
Co-administration of Amobarbital and Osteokit may decrease the effects of Osteokit.

How to manage the interaction:
Co-administration of Osteokit with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Osteokit:
Taking Osteokit with Fosphenytoin can reduce the levels and efficacy of Osteokit.

How to manage the interaction:
Taking Osteokit with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Osteokit:
Co-administration of Osteokit with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Osteokit can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Osteokit:
Co-administration of Isoniazid with Osteokit may decrease the effects of Osteokit.

How to manage the interaction:
Although there is an interaction, Osteokit can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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CALCITRIOL-0.25MG+CALCIUM-200MG+IBANDRONIC ACID-150MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate

Drug-Food Interactions

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CALCITRIOL-0.25MG+CALCIUM-200MG+IBANDRONIC ACID-150MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
foods high in oxalic acid (spinach) may decrease calcium absorption. Consider taking calcium at least 2 hours before or after eating meals high in oxalic acid or phytic acid.

Diet & Lifestyle Advise

  • Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.
  • Include zinc-rich sources like meat, shellfish, legumes, hemp seeds, nuts, eggs, dairy products, whole grains, potatoes, kale, and dark chocolate in your diet.
  • Snack on calcium-rich nuts like Brazil nuts or almonds. 
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

BONE ENHANCERS
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Osteokit.

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Pregnancy

Caution

Ibandronic acid in Osteokit is not recommended during pregnancy. Please consult your doctor for more information.

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Breast Feeding

Caution

Consult your doctor before taking Osteokit if you are breastfeeding. Osteokit can pass into the breast milk. Ibandronic acid in Osteokit is not recommended during breastfeeding.

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Driving

Safe if prescribed

Osteokit has negligible effects on driving ability.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Osteokit. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek doctor advice before starting Osteokit if you have kidney stones or undergoing dialysis. Calcitriol in Osteokit increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Unsafe

Osteokit is not recommended for children and adolescents below 18 years.

Have a query?

FAQs

Osteokit treats low levels of calcium in the blood and osteoporosis. It consists of Calcium, Calcitriol, Zinc, and Ibandronic acid. These medicines help in providing calcium to the body and help in bone formation and maintenance. Osteokit further helps in restoring bone mass and reduces the chances of easy fractures.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Osteokit may cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Osteokit if you have any kidney problems or a history of kidney stones.

Osteokit is used to increase low levels of calcium in the body. Hence it is not advised to use Osteokit during hypercalcemia since it causes the overdose of calcium leading to kidney stones and other effects.

Calcitriol in Osteokit can increase inorganic phosphate levels in serum; hence it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low phosphate diet to control serum phosphorus levels in patients undergoing dialysis.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - OST0076

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