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Nadix-A Cream is used to treat acne. It contains Adapalene and Nadifloxacin which unblocks pores by reducing oil production in the skin and kills acne-causing bacteria. This medicine may sometimes cause side effects such as skin peeling, dry skin, irritation, redness, itching, or burning sensation at the site of application. It is for external use only.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Canbro Healthcare

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Nadix-A Cream

Nadix-A Cream is a topical medicine prescribed to treat acne vulgaris. It combines nadifloxacin, a fluoroquinolone antibiotic, and adapalene, a third-generation synthetic retinoid, to treat acne from different angles. It helps clear active pimples, blackheads, and whiteheads while reducing inflammation and helping prevent new breakouts.

To achieve the best results, apply this medicine exactly as directed by your doctor, usually once daily in the evening. Apply it only to clean, dry skin and use it on the affected areas only. Following a gentle skincare routine, using non-comedogenic products, and maintaining a balanced diet may also help support healthy skin.

While using this medicine, you may experience mild side effects such as temporary dryness, peeling, redness, or a mild burning or stinging sensation. These effects are usually temporary and improve as your skin adjusts. However, stop using the gel and contact your doctor if you develop severe skin irritation, swelling, blistering, or signs of an allergic reaction.

Talk to your doctor before using this medicine if you have very sensitive skin, eczema, seborrheic dermatitis, or severe sunburn. Do not use it if you are allergic to nadifloxacin, adapalene, or any of the other ingredients.

Avoid using this gel together with other irritating topical products, harsh cleansers, alcohol-based skincare products, or unnecessary antibiotic acne treatments unless advised by your doctor. If you are pregnant or planning to become pregnant, consult your doctor before using this medicine because adapalene (the retinoid component) is generally not recommended during pregnancy. If you are breastfeeding, ask your doctor whether this medicine is suitable for you.

Uses of Nadix-A Cream

Nadix-A Cream is used in the treatment of Acne (pimples). The detailed uses of Nadix-A Cream are as follows:

  • Acne vulgaris: Nadix-A Cream helps clear active breakouts, including inflammatory pimples, blackheads, and whiteheads, by stopping bacterial growth and keeping skin pores clear.

Key Benefits

Nadix-A Cream offers targeted relief from frustrating skin breakouts, helping you regain confidence with clearer, healthier skin. Benefits may include:

  • Faster healing of pimples: It speeds up the recovery of inflamed red bumps, reducing their size and severity.
    Prevention of new breakouts: By keeping your pores clear of dead skin cells and excess oil, it stops new acne from forming.
  • Smoother skin texture: The gentle peeling action helps smooth rough patches and uneven skin texture caused by acne.
  • Reduced skin redness: It calms the surrounding skin, minimizing the overall redness and swelling associated with acne flare-ups.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Take a small amount of Nadix-A Cream on the fingertip and apply it as a thin layer on the clean and dry affected area as advised by your doctor.
  • Nadix-A Cream is only for external use. Do not apply Nadix-A Cream on the broken skin or wounds.

How Nadix-A Cream Works

Nadix-A Cream is a combination of Nadifloxacin and Adapalene. Nadifloxacin is a topical fluoroquinolone antibiotic that blocks bacterial enzymes (DNA gyrase and topoisomerase IV), helping reduce acne-causing bacteria and inflammatory pimples. Adapalene is a third-generation synthetic retinoid that keeps pores clear by normalizing skin cell turnover. It also reduces inflammation, helping improve redness and swelling. Together, they clear existing acne, help prevent new breakouts, and improve overall skin texture over time.
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Alcohol

Caution

The interaction of Nadix-A Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Nadix-A Cream.

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Pregnancy

Caution

The safety of Nadix-A Cream in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Do not apply Nadix-A Cream on the breast. You are advised to breastfeed only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Nadix-A Cream usually does not affect your ability to drive or operate machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Nadix-A Cream in patients with liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Nadix-A Cream in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Nadix-A Cream is not recommended for children aged below 12 as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Nadix-A Cream. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Nadix-A Cream in elderly patients. Please consult your doctor.

What if I have taken an overdose of Nadix-A Cream

Because this is a topical medicine, a serious overdose from applying it to the skin is highly unlikely. However, applying too much can cause severe skin redness, peeling, and discomfort. If you or someone else accidentally swallows the gel, seek immediate medical attention or contact your local poison control center right away.

Diet & Lifestyle Advise

  • Choose non-comedogenic products: Always look for oil-free, non-comedogenic skincare products, sunscreens, and makeup to ensure they do not clog your pores while you are undergoing treatment.
  • Protect your skin from the sun: This medicine makes your skin highly sensitive to sunburn. Apply a broad-spectrum sunscreen with SPF 30 or higher every morning, and wear protective clothing when spending time outdoors.
  • Do not pick or squeeze pimples: Squeezing or popping blemishes can push bacteria deeper into the skin, worsen inflammation, prolong healing time, and lead to permanent scarring.
  • Use a gentle touch: Avoid using harsh facial scrubs, exfoliating brushes, or rough washcloths. Wash your face gently with your fingertips to prevent aggravating irritated skin.
  • Stay hydrated and eat balanced meals: Drink plenty of water to keep your skin hydrated from within, and try to limit highly processed, sugary foods, which some studies suggest can trigger acne flare-ups.
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How Soon It Starts Working

The time required for Nadix-A Cream to start to work: The time required for Nadix-A Cream to show its action is unknown. The time for which the effects of Nadix-A Cream last: The duration of action for Nadix-A Cream is clinically unknown.

Storage

• Store Nadix-A Cream at controlled room temperature, between 15°C and 30°C (59°F to 86°F). • Keep the tube tightly closed when not in use to protect the medicine from moisture and air.

What if you forget to take Nadix-A Cream

If you miss an application, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply double the amount to make up for a missed application.

Drug Warnings

  • Perform a patch test: Before using the gel on your face for the first time, apply a tiny amount to a small, hidden patch of skin for 3 days to make sure you do not experience a severe allergic reaction.
  • Inspect the tube before use: Check the tube seal before your first use. Do not use the gel if the packaging appears punctured, damaged, or leaking.
  • Keep away from sensitive areas: Ensure the gel does not get into your eyes, nostrils, mouth, or onto sensitive mucous membranes. If accidental contact occurs, rinse immediately with plenty of cool water.
  • Avoid compromised skin: Do not apply this gel to skin that is sunburned, windburned, cut, scraped, or affected by other conditions like eczema or psoriasis.
  • Avoid harsh skin procedures: Do not undergo hair waxing, chemical peeling, or laser skin treatments on the areas where you apply this medicine, as your skin will be too sensitive.
  • Use this medicine only for the duration prescribed. Prolonged or unnecessary use of topical antibiotics, including nadifloxacin, may contribute to bacterial resistance and reduce their effectiveness over time.

verifiedApollotooltip
  • Other topical acne treatments: Using other products containing peeling agents like salicylic acid, sulfur, or resorcinol alongside Nadix-A Cream can significantly increase the risk of severe skin dryness, redness, and peeling.
  • Astringents and alcohol-heavy cosmetics: Medicated or abrasive soaps, cosmetics with a strong drying effect, and products containing high concentrations of alcohol or lime can cause extreme skin irritation when combined with this gel.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Nadix-A Cream when used as directed.

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Habit Forming

No

Therapeutic Class

[ANTI BACTERIALS - TOPICAL]

FAQs

Nadix-A Cream is used to treat acne (pimples).
Yes, Nadix-A Cream may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
No, Nadix-A Cream is not recommended for eczema (itchy, cracked, swollen or rough skin) patients as it may increase the risk of severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Nadix-A Cream.
Yes, Nadix-A Cream may cause skin irritation or sensitivity as a side effect. However, if the irritation persists or worsens, stop using Nadix-A Cream and consult a doctor.
Yes, Nadix-A Cream may cause dryness of the skin. You can use a moisturizer while using Nadix-A Cream to prevent dry skin. However, do not apply Nadix-A Cream and moisturizer simultaneously as it may reduce the effectiveness of Nadix-A Cream. Please consult a doctor before using other products with Nadix-A Cream.
No, you are not recommended to stop taking Nadix-A Cream without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Nadix-A Cream for as long as your doctor has prescribed it, and if you experience any difficulty while taking Nadix-A Cream, please consult your doctor.
Nadix-A Cream is a combination of two medicines: Adapalene (human-made vitamin A) and Nadifloxacin (antibiotic). Adapalene is a retinoid (human-made vitamin A) that works by loosening the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Nadifloxacin belongs to the class of antibiotics that works by inhibiting the production of essential proteins that are necessary for bacteria to grow, multiply and increase in numbers. It prevents the growth of acne-causing bacteria. Altogether, it stops or slows down the growth of bacteria and prevents the growth of acne.
The side effects of Nadix-A Cream include skin peeling, irritation, redness, dry skin, itching, or burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, consult the doctor if these side effects persist or worsen.
Nadix-A Cream is primarily used to treat acne, but adapalene present in Nadix-A Cream may help fade dark spots over time. However, it is not specifically formulated for dark spot removal. Please consult the doctor for alternative treatments specifically designed for dark spot removal.
Yes, Nadix-A Cream may cause skin peeling as a side effect, especially if you have sensitive skin. This is due to the exfoliating properties of its active ingredients. Please consult a doctor if the peeling persists or worsens for further guidance.
Nadix-A Cream is not recommended for use in children under 12 years of age, as its safety and effectiveness have not been established in this age group. Please consult the doctor if you have any concerns.
The duration of treatment with Nadix-A Cream may vary depending on your skin condition and doctor's advice. It is usually recommended for short-term use, ranging from a few weeks to a few months. Still, long-term use should be avoided without consulting your doctor, as it may lead to adverse effects.
It is generally best to apply Nadix-A Cream in the evening because some of its ingredients can make your skin much more sensitive to sunlight and UV rays. If your doctor advises you to apply it during the day, make sure to use a high-quality, broad-spectrum sunscreen afterward. Talk to your doctor or pharmacist for guidance on sun protection.
Mild peeling, dryness, and redness are very common when you first start using Nadix-A Cream. You can manage this by applying a gentle, fragrance-free, oil-free moisturizer daily. If the irritation becomes severe, painful, or very red, talk to your doctor, as they may suggest reducing how often you apply the gel.
If you are pregnant or planning to become pregnant, talk to your doctor before using this medicine. The main concern is adapalene, a topical retinoid, which is generally not recommended during pregnancy because of its potential risk to the developing baby, even though the amount absorbed through the skin is very low. Topical nadifloxacin is absorbed into the bloodstream only in very small amounts. If you are breastfeeding, your doctor will decide whether this medicine is appropriate for you and advise you to avoid applying it to areas that may come into direct contact with your baby.
Yes, you can wear makeup, but you should apply Nadix-A Cream to clean skin first and allow it to dry completely. Always choose oil-free or non-comedogenic cosmetics so you do not block your pores and reduce the effectiveness of the treatment. Talk to your doctor or pharmacist about skin-friendly makeup options.
Yes, Nadix-A Cream can be used on other body areas affected by acne, such as the chest or back, if your doctor has directed you to do so. However, because skin thickness varies across the body, talk to your doctor before applying it to areas other than your face.
If the gel accidentally gets into your eyes, mouth, or nose, rinse the area immediately and thoroughly with plenty of cool water. If you experience persistent burning, swelling, or vision changes, seek medical attention. Talk to your doctor if you have any ongoing discomfort.
Using other prescription or over-the-counter acne products at the same time may increase dryness, redness, and skin irritation. Some products may also contain additional antibiotics or exfoliating agents that are not needed. Use other acne treatments only if recommended by your healthcare provider, and avoid continuing topical antibiotics longer than prescribed to help reduce the risk of antibiotic resistance. Talk to your doctor about the skincare products you currently use

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Country of origin

India
Other Info - NA56534
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