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Melalong Ad Cream is a combination medicine used in the treatment of dark patches caused by hyperpigmentation, age, and UV radiation. This medicine reduces the melanin (skin pigment) in the dark spots, thereby lightening sunspots and age spots. Common side effects include stinging, tingling, dry skin, burning sensation, and irritation

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MEQUINOL-2%W/W+TRETINOIN-0.01%W/W

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Melalong Ad Cream

Melalong Ad Cream is a prescription topical medicine used to treat solar lentigines, which are commonly known as age spots or sun spots. Its medical purpose is to gradually lighten these flat, dark patches of skin that develop from years of exposure to ultraviolet light. This skin-lightening treatment helps even out your skin tone when applied directly to the affected areas.

To achieve the best results, you must apply Melalong Ad Cream consistently, usually twice a day spaced about 12 hours apart, or exactly as directed by your healthcare provider. Because this is a topical medicine applied directly to the skin, food intake does not affect how it works, but you should always apply it to clean, dry skin. Wearing broad-spectrum sunscreen daily and avoiding direct sunlight are essential lifestyle changes that protect your skin and help this medicine work effectively.

While using Melalong Ad Cream, you may notice mild skin changes like redness, peeling, dry skin, or a temporary stinging sensation. These are common and often resolve as your skin adjusts, but you should consult your doctor immediately if you experience severe blistering, intense burning, or swelling. If you notice any unusual changes in your skin color outside the treated areas, contact your healthcare provider right away.

Talk to your doctor before starting this medicine if you have sensitive skin, eczema, rosacea, or a history of skin pigment disorders. Do not use this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as some components can be absorbed through the skin and may cause harm. Your doctor can help you weigh the risks and benefits of this treatment.

Avoid using other irritating topical products, such as strong soaps, peeling agents, or cosmetics containing high amounts of alcohol, as they can cause severe skin dryness and irritation. It is also important for elderly individuals or those with highly sensitive skin to consult their healthcare provider to ensure safe application. Always discuss all other skin products you are currently using with your pharmacist or doctor.

Uses of Melalong Ad Cream

This medicine is used to help reduce the appearance of dark spots and uneven skin pigmentation. The detailed uses of this medicine are as follows:

  • Solar lentigines: This medicine helps fade flat, dark spots (commonly called age spots or sun spots) that appear on sun-exposed areas of the skin, such as the face, hands, and forearms.
  • Hyperpigmentation: It helps lighten localized patches of darkened skin by regulating the cells that produce skin color.

Key Benefits

Melalong Ad Cream helps improve skin appearance by reducing pigmentation and promoting healthier skin renewal. Its benefits include:

  • Helps fade stubborn dark spots and sun spots by targeting areas of excess pigmentation.
  • Promotes a more even and balanced skin tone by reducing visible discoloration.
  • Supports skin renewal by encouraging the removal of dull, dead skin cells.
  • Helps improve skin texture, making the skin appear smoother and healthier.
  • Enhances overall skin appearance by supporting a clearer and more uniform complexion.

Directions for Use

  • Follow your doctor's instructions on the dose and duration.
  • Apply Melalong Ad Cream as a spot corrector on only the spots identified as pigmentation by your doctor, and avoid getting Melalong Ad Cream anywhere on the surrounding skin.
  • Do not wash your face after applying Melalong Ad Cream. Wait for at least half an hour before applying any makeup on the treated area. Do not bathe or shower for at least 6 hours post-application.

How Melalong Ad Cream Works

Melalong Ad Cream contains Mequinol and Tretinoin. Mequinol: It helps reduce the activity of pigment-producing cells (melanocytes) that make melanin, the pigment responsible for skin color. By decreasing melanin production, it helps prevent the formation of new dark spots and gradually lightens existing areas of hyperpigmentation. Tretinoin: It is a retinoid that promotes skin cell renewal by increasing the shedding of old, pigmented skin cells. It helps reveal newer skin cells and improves the penetration of mequinol, enhancing the overall skin-lightening effect.
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Alcohol

Caution

Melalong Ad Cream may interact with alcohol. Proceed with caution.

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Pregnancy

Unsafe

Melalong Ad Cream is not recommended for use during pregnancy or if you are trying to conceive, as it can cause foetal harm.

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Breast Feeding

Caution

Caution must be exercised before using Melalong Ad Cream during breastfeeding as it is not known whether it is excreted in breast milk. Please consult your doctor to address any concerns.

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Driving

Safe if prescribed

Melalong Ad Cream is unlikely to affect your ability to drive.

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Liver

Caution

Exercise caution in case of established liver disease or hepatic dysfunction. Please consult your doctor in case of any concerns.

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Kidney

Safe if prescribed

Melalong Ad Cream is safe on the kidney. Please consult your doctor in case of any concerns.

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Children

Caution

Not enough studies have been conducted to establish the effects of Melalong Ad Cream in children below 12 years of age. Please consult your physician in case of any concerns.

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Heart

Consult your doctor

Consult your doctor if you have a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Melalong Ad Cream should be used in elderly patients only if prescribed by a doctor. If you have any concerns about using Melalong Ad Cream in older adults, please consult your doctor.

What if I have taken an overdose of Melalong Ad Cream

Because Melalong Ad Cream is a topical medicine, an overdose is unlikely when used as directed. However, applying too much can cause severe redness, peeling, or discomfort. If you accidentally swallow the medicine, or if you experience severe skin irritation from applying too much, contact your doctor or seek immediate medical attention.

Diet & Lifestyle Advise

  • Use sunscreen daily: Apply a broad-spectrum sunscreen with an SPF of 30 or higher every single day, even when it is cloudy or if you are indoors near windows. The active ingredients make your skin highly sensitive to ultraviolet light.
  • Wear protective clothing: Cover treated areas with tightly woven clothing, and wear a wide-brimmed hat to protect your face from direct sunlight when outdoors.
  • Avoid tanning: Do not use tanning beds, sunlamps, or spend prolonged periods sunbathing while using this treatment, as this can worsen hyperpigmentation and cause severe skin burns.
  • Moisturize regularly: Use a gentle, fragrance-free moisturizer to help soothe dry, flaking skin, but apply it only after Melalong Ad Cream has dried completely.
  • Avoid harsh skin products: Steer clear of abrasive scrubs, waxing, chemical peels, or other irritating skincare products on the treated areas to prevent severe skin damage.
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Have a query?

How Soon It Starts Working

The time required for Melalong Ad Cream to start to work: The time required for Melalong Ad Cream to show its action is unknown. The time for which the effects of Melalong Ad Cream last: The duration of action for Melalong Ad Cream is clinically unknown.

Storage

• Store the medicine at room temperature, ideally between 15°C and 30°C (59°F to 86°F).• Store the product away from direct light, high heat, and moisture.

What if you forget to take Melalong Ad Cream

If you miss an application, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and return to your regular routine. Do not apply extra medicine to make up for a missed application.

Drug Warnings

  • Apply with precision: Use a cotton swab or the designated applicator to touch only the dark spots, keeping the cream away from unaffected skin to avoid unwanted halos of light skin.
  • Protect sensitive areas: Never apply this medicine close to your eyes, mouth, corners of your nose, or on open cuts and scratched skin.
  • Weather sensitivity: Be cautious in extreme cold or wind, as treated skin can become extra sensitive to chapping and irritation during harsh weather.
  • Pause during sunburn: If you develop a sunburn on the treated areas, stop using Melalong Ad Cream and wait until your skin has completely healed before restarting.

Drug-Drug Interactions

verifiedApollotooltip
  • Topical peeling agents (such as sulfur, salicylic acid, or resorcinol): May cause severe skin irritation, peeling, and dryness when used on the same skin areas as Melalong Ad Cream.
  • Skin products containing alcohol or astringents: Using hair removers, medicated soaps, or alcohol-containing cosmetics can lead to intense burning and stinging.
  • Medicines that increase sun sensitivity (such as certain diuretics or antibiotics): May greatly increase your risk of severe sunburn when combined with this topical treatmen
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Melalong Ad Cream when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS DERMATOLOGICALS]

FAQs

Melalong Ad Cream is used in the treatment of dark patches caused by hyperpigmentation, age, and UV radiation. It is effective in lightening sunspots and age spots. Melalong Ad Cream also helps in preventing acne in oily, acne-prone skin.
Melalong Ad Cream works by suppressing melanin production, thereby reducing pigmentation and discolouration. Melalong Ad Cream also regulates skin turnover and helps in the prevention of acne.
While Melalong Ad Cream is suitable for all skin types if indicated, Melalong Ad Cream may cause dry skin. Hence, it is best to consult your dermatologist before using Melalong Ad Cream if you have very dry skin.
It is not advisable to leave the skin bare. Using a non-alcoholic moisturiser on top of Melalong Ad Cream really helps seal it in, allowing Melalong Ad Cream to work more effectively. Wait for at least 15 minutes before applying the moisturiser after using Melalong Ad Cream.
No, you should not use Melalong Ad Cream if you are pregnant, planning to become pregnant, or breastfeeding. Some components of this medicine can be absorbed through the skin and may pose risks to a developing baby. Talk to your doctor about safer skin treatments during pregnancy.
Yes, you can apply makeup over Melalong Ad Cream, but you must wait at least 20-30 minutes to allow the cream to dry completely. Always ensure the medicine is fully absorbed so that makeup application does not spread the product to untreated skin. Talk to your doctor or pharmacist for specific product recommendations.
Mild peeling and redness are common skin reactions when starting Melalong Ad Cream. You can manage this by applying a gentle, fragrance-free moisturizer after the medicine has dried. If the peeling becomes severe, painful, or causes blistering, stop using the product and talk to your doctor.
Melalong Ad Cream is commonly prescribed for sun spots on the face, hands, and forearms. However, you should only apply it to the specific areas recommended by your healthcare provider, as skin thickness varies across the body. Talk to your doctor before applying it to new areas.
Yes, Melalong Ad Cream significantly increases your skin's sensitivity to UV light, which can lead to severe sunburns or make your dark spots return. It is essential to wear a broad-spectrum sunscreen with SPF 30 or higher and protective clothing daily. Talk to your doctor if you experience a sunburn.
Using other active skincare products like retinol, vitamin C, or exfoliating acids at the same time can cause severe irritation, dryness, and peeling. If you want to use these products, you should discuss a safe skincare routine with your healthcare provider. Talk to your doctor or pharmacist before combining treatments.
If you stop using Melalong Ad Cream, your treated skin spots may gradually return to their original darker color over time, especially if the skin is exposed to sunlight without protection. Consistent sun protection is required even after stopping the medicine. Talk to your doctor for guidance on maintaining your results.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 020922S006Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 020922S003Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. Mayo Clinic Staff. Drg 20062170 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  4. National Center for Biotechnology Information (NCBI). Mequinol + Tretinoin Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Mequinol And Tretinoin Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. DrugBank Online. Db09516 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
  7. Drugs.com Clinical Review Team. Tretinoin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - MEL0286

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