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MACROGOL SACHET is used to treat constipation. It works by drawing water into the intestine, which softens the stools, making them easier to pass. In some cases, this medicine may cause side effects such as stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

POLYETHYLENE GLYCOL-13.125GM+POTASSIUM CHLORIDE-46.6MG+SODIUM BICARBONATE-178.5MG+SODIUM CHLORIDE-350.7MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About MACROGOL SACHET

MACROGOL SACHET is a medicine used to treat ongoing constipation and to clear the digestive tract completely before medical tests or surgeries. It works by bringing water into your bowel, which softens your stool and makes bowel movements more frequent and easier to pass. This helps ensure your intestines are completely clear for diagnostic procedures like colonoscopies.

To get the best results, you must take the MACROGOL SACHET exactly as directed by your doctor. If you are taking it for daily constipation, consistency is key, and you should take it at the same time each day, with or without food. Along with taking this medicine, drinking plenty of water, eating fiber-rich foods, and staying physically active can significantly improve your digestive health.

While taking MACROGOL SACHET, some people may experience mild stomach discomfort, bloating, or nausea. These symptoms are usually temporary, but if you experience severe vomiting, severe abdominal pain, or blood in your stool, you should contact your doctor immediately.

Do not take this if you have a bowel obstruction, a tear in your stomach or intestinal wall, or severe inflammatory bowel conditions. Always talk to your doctor before starting MACROGOL SACHET if you have kidney problems, heart conditions, or a history of salt imbalances in your blood.

Because MACROGOL SACHET works by flushing your bowel, it can prevent other oral medicines from being absorbed properly if taken at the same time. Talk to your doctor or pharmacist if you take blood pressure medications, or if you are pregnant, breastfeeding, or elderly, to ensure you can use this medicine safely.

Uses of MACROGOL SACHET

MACROGOL SACHET is used to relieve constipation and cleanse the bowel before certain medical procedures. The detailed uses are as follows:

  • Chronic constipation: MACROGOL SACHET helps by drawing water into the bowel to soften dry, hard stool, making it much easier to pass.
  • Bowel cleansing before medical procedures: MACROGOL SACHET clears out the digestive tract completely so that doctors can get a clear view during examinations like colonoscopies or X-rays.

Key Benefits

MACROGOL SACHET helps relieve constipation, promote comfortable bowel movements, and support effective bowel cleansing. The key benefits include:

  • Relieves constipation: Softens stools and makes bowel movements easier to pass.
  • Promotes comfortable bowel movements: Helps reduce straining and discomfort during defecation.
  • Supports bowel cleansing: Effectively clears the bowel before medical procedures such as colonoscopy.
  • Helps maintain hydration: The added electrolytes help reduce the risk of dehydration during bowel preparation.
  • Supports effective diagnosis: A well-cleansed bowel allows better visualisation during diagnostic procedures.
  • Improves digestive comfort: Helps relieve the discomfort associated with chronic constipation.

Directions for Use

  • MACROGOL SACHET can be taken with or without food, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions. Dilute MACROGOL SACHET with water as advised by your doctor. Take it orally using the measuring cup provided with the package.
  • Shake the bottle well before each use.

How MACROGOL SACHET Works

MACROGOL SACHET contains polyethylene glycol, potassium chloride, sodium bicarbonate, and sodium chloride, which work together to relieve constipation and cleanse the bowel while maintaining the body's fluid and electrolyte balance. Polyethylene glycol is an osmotic agent that binds to water and carries it into the colon, where it softens hard stools, increases stool volume, and stimulates natural bowel movements. Potassium chloride, sodium bicarbonate, and sodium chloride replace essential electrolytes that may be lost during bowel cleansing, helping maintain hydration and normal electrolyte levels. Together, these ingredients provide effective bowel cleansing while reducing the risk of dehydration and electrolyte imbalance.
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Alcohol

Consult your doctor

The interaction of alcohol with MACROGOL SACHET is unknown. Please consult a doctor before consuming alcohol while using MACROGOL SACHET.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. MACROGOL SACHET is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. MACROGOL SACHET is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe

MACROGOL SACHET usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take MACROGOL SACHET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take MACROGOL SACHET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

MACROGOL SACHET is not recommended for children under 12 years of age, as its safety and effectiveness have not been established.

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Heart

Caution

MACROGOL SACHET should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking MACROGOL SACHET.

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Geriatrics

Caution

MACROGOL SACHET should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using MACROGOL SACHET.

What if I have taken an overdose of MACROGOL SACHET

If you take more than the recommended dose of MACROGOL SACHET, seek immediate medical attention. Symptoms of an overdose may include severe diarrhoea, dehydration, or electrolyte imbalance.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of clear fluids, such as water, clear broths, or herbal teas, especially when using MACROGOL SACHET for bowel preparation.
  • Increase dietary fibre: If treating constipation, gradually include more fruits, vegetables, and whole grains in your diet to support regular bowel movements.
  • Stay physically active: Engage in light exercise, such as daily walking, to help stimulate natural bowel function.
  • Avoid gas-producing foods and drinks: Limit carbonated beverages and foods that commonly cause bloating or excess gas.
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How Soon It Starts Working

The time required for MACROGOL SACHET to start to work: The time required for MACROGOL SACHET to show its action is unknown.

The time for which the effects of MACROGOL SACHET last: The duration of action for MACROGOL SACHET is clinically unknown.

Storage

•Store the unmixed powder at 15°C to 30°C in a cool, dry place away from heat, direct light, and moisture. Do not store it in the bathroom.

What if you forget to take MACROGOL SACHET

If you are taking MACROGOL SACHET daily for constipation and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are preparing for a medical procedure and miss a dose or fall behind on your drinking schedule, contact your doctor or the clinic immediately for guidance.

Drug Warnings

  • Check the prepared solution: Drink the solution only if it is clear and free of undissolved powder. Do not use it if it appears cloudy or discoloured.
  • Do not alter the solution: Do not add sugar, flavourings, or thickeners, as they may affect how MACROGOL SACHET works.
  • Chill before use: Refrigerating the prepared solution may improve its taste. Do not freeze it.
  • Manage bloating: If you develop severe abdominal bloating or distension, slow down or temporarily stop drinking the solution until the symptoms improve.
  • Special dietary restrictions: Consult your doctor before using MACROGOL SACHET if you are on a sodium-restricted or potassium-restricted diet.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with MACROGOL SACHET and may require closer monitoring:

  • Oral medicines: Taking other oral medicines within 1 hour of MACROGOL SACHET may reduce their absorption and effectiveness.
  • Diuretics (water tablets) and blood pressure medicines: Taking these with MACROGOL SACHET may increase the risk of dehydration or electrolyte imbalance. Your doctor may recommend closer monitoring.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chloridePhenindamine
Critical
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideEplerenone
Critical

Drug-Drug Interactions

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Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chloridePhenindamine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Macrogol Sachet 14gm together with Phenindamine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm together with Phenindamine is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideEplerenone
Critical
How does the drug interact with Macrogol Sachet 14gm:
Using Macrogol Sachet 14gm together with Eplerenone may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Macrogol Sachet 14gm with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideOrphenadrine (citrate)
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Macrogol Sachet 14gm with Orphenadrine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm with Orphenadrine is not recommended, as it can lead to an interaction, can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideBiperiden
Critical
How does the drug interact with Macrogol Sachet 14gm:
Co- administration of Macrogol Sachet 14gm with Amitriptyline may cause stomach and upper intestinal discomfort.

How to manage the interaction:
Taking Macrogol Sachet 14gm with Biperiden is not recommended as it can lead to an interaction, but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideTrospium
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Macrogol Sachet 14gm with Trospium can increase the risk of stomach ulcers and bleeding

How to manage the interaction:
Taking Macrogol Sachet 14gm with Trospium is not recommended as it may lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideTolterodine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Macrogol Sachet 14gm together with Tolterodine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm together with Tolterodine is not recommended, as it can lead to an interaction, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or loss of appetite. Do not discontinue medications without consulting a doctor.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideSolifenacin
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Macrogol Sachet 14gm together with Solifenacin can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm with Solifenacin is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideDoxepin
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Doxepin with Macrogol Sachet 14gm with doxepin can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm with Doxepin is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideOxybutynin
Critical
How does the drug interact with Macrogol Sachet 14gm:
Co-administration of Macrogol Sachet 14gm with Oxybutynin can increase the risk of developing stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm with Oxybutynin is not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult a doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.
Macrogol + Potassium chloride + Sodium bicarbonate + Sodium chlorideDicyclomine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Co-administration of Macrogol Sachet 14gm with Dicyclomine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Macrogol Sachet 14gm with Dicyclomine is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Starch-based food thickeners: Do not mix MACROGOL SACHET with starch-based thickeners, as it can reduce the effectiveness of both products.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[LAXATIVES]

FAQs

MACROGOL SACHET belongs to a class of drugs called laxatives, used to treat constipation.
MACROGOL SACHET contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making it easier to pass. Potassium chloride is essential for the healthy functioning of organs. Sodium bicarbonate works by neutralising high levels of acid in the stomach, helping to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in relieving constipation.
MACROGOL SACHET may cause mild diarrhoea as a side effect at the beginning of the treatment. It usually gets better by reducing the amount of MACROGOL SACHET intake. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take MACROGOL SACHET with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking MACROGOL SACHET with other medicines.
You are recommended to avoid foods that are high in fat and low in fibre, such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.
You are not recommended to take more than the advised dose of MACROGOL SACHET as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking MACROGOL SACHET and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.
It is best to dissolve the powder only in water as directed on the package. Mixing it with juice, soda, or other drinks can alter the concentration of salts and affect how the medicine works. Talk to your doctor or pharmacist before adding anything to the solution.
If you are taking MACROGOL SACHET to cleanse your bowel before a medical procedure, you must avoid solid foods and only consume clear liquids. If you are taking it for daily constipation, you can eat normally. Talk to your doctor for specific dietary guidelines.
Since MACROGOL SACHET is minimally absorbed by the body, it is generally considered safe, but you should always talk to your doctor before taking any laxative during pregnancy or breastfeeding.
If you feel nauseous, try drinking the solution more slowly or take a brief break of 15 to 30 minutes before resuming. Drinking the solution chilled can also help reduce nausea. Talk to your doctor if the nausea is severe or if you vomit.
Mild stomach cramps and bloating are common side effects as the medicine works to move stool through your bowels. However, if you experience severe, sharp, or persistent stomach pain, stop taking the medicine and contact your doctor immediately.
MACROGOL SACHET can prevent other oral medicines from being absorbed properly because it speeds up bowel movements. You should take your other oral medications at least 1 hour before or 1 hour after taking MACROGOL SACHET. Talk to your doctor or pharmacist to plan your medication schedule safely.
Your bowel preparation is typically complete when your bowel movements become clear, yellowish, and free of solid matter. If your stool is still dark or contains solid particles near the time of your procedure, contact your doctor's clinic for advice.

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Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - MAC0064

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