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Macox-Plus Kid Tablet is used to treat and prevent tuberculosis (TB) in children weighing less than 25 kg. It kills the TB-causing bacteria by blocking essential processes needed for their growth, helping clear infections in the lungs and other parts of the body and reducing the risk of drug resistance.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Macox-Plus Kid Tablet

Macox-Plus Kid Tablet is used to prevent and treat tuberculosis in children who weigh less than 25 kg. Tuberculosis (TB) is an infectious disease that mainly affects the lungs, but it can also spread to other parts of the body, such as the kidneys, brain, spine, and bone marrow.

Macox-Plus Kid Tablet contains Rifampicin and Isoniazid, which work together to kill the bacteria that cause tuberculosis (TB). They stop the bacteria from growing and spreading, helping the body fight and clear the infection.

Macox-Plus Kid Tablet is for paediatric use only. Give Macox-Plus Kid Tablet to your child exactly as prescribed by the doctor. Macox-Plus Kid Tablet may sometimes cause side effects such as nausea, vomiting, diarrhoea, stomach pain, loss of appetite, itching, and tingling or numbness of the skin. Please consult the doctor if any side effects persist or worsen.

Before starting Macox-Plus Kid Tablet , inform your doctor if your child is allergic to any ingredients and about any health conditions or medicines they are taking. Give Macox-Plus Kid Tablet for the full prescribed course for effective treatment.

Uses of Macox-Plus Kid Tablet

Macox-Plus Kid Tablet is used in the treatment of tuberculosis in children. The detailed uses of Macox-Plus Kid Tablet are as follows:

  • Treatment and Prevention of Active Tuberculosis (TB): Macox-Plus Kid Tablet is used in children who weigh less than 25 kg to help prevent and treat active TB caused by Mycobacterium tuberculosis.

Key Benefits

Macox-Plus Kid Tablet offers the following medicinal benefits:

  • Used to treat active tuberculosis (TB) in children as part of combination therapy.
  • Helps prevent TB in children who are at high risk of developing the infection.
  • Stops bacteria from making essential proteins and forming their cell wall, thereby killing Mycobacterium tuberculosis and clearing the TB infection.
  • Helps reduce the risk of drug resistance by combining two antibiotics.
Side effects of Macox-Plus Kid Tablet

Directions for Use

  • Macox-Plus Kid Tablet should be administered on an empty stomach (at least 1 hour before or 2 hours after a meal), or as directed by the doctor.
  • The doctor will decide the dosage and timing of this medicine based on your child’s age and weight. It is typically given once daily at the same time each day.
  • Add the prescribed number of tablets to a clean cup of water, stir gently until fully dissolved, and give the mixture to your child immediately.
  • Do not chew or swallow the tablets whole.

How Macox-Plus Kid Tablet Works

Macox-Plus Kid Tablet contains two antimycobacterial drugs: Rifampicin and Isoniazid. • Rifampicin: Stops the TB bacteria from multiplying. • Isoniazid: Weakens and damages the bacteria. Together, they kill the bacteria that cause tuberculosis (TB) and help clear the infection.
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Consult your doctor

Please consult the doctor if your child has liver problems or if you have any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if your child has kidney problems or if you have any concerns regarding this.

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Children

Safe if prescribed

Macox-Plus Kid Tablet is safe for children if prescribed by a doctor. The doctor will decide the dose and duration based on your child’s age and weight.

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Heart

Consult your doctor

Please consult the doctor if your child has heart problems or if you have any concerns regarding this.

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Geriatrics

Not applicable

It is intended for Children.

What if I have taken an overdose of Macox-Plus Kid Tablet

Do not give more than the prescribed dose of Macox-Plus Kid Tablet to your child, as it may cause serious side effects. If you suspect an overdose or notice any unusual symptoms in your child, please consult a doctor immediately.

Diet & Lifestyle Advise

Dietary recommendations:

  • Include foods rich in vitamin C, such as kiwi, broccoli, and bell peppers, in your child’s meals to help support their immune system.
  • Give warm fluids like soups to help soothe a sore throat and make coughing less uncomfortable.
  • Pineapple juice might help ease coughing due to its mild anti-inflammatory and mucolytic properties.
  • Help your child stay well-hydrated with plenty of water and other healthy drinks.
  • Avoid giving your child processed or packaged foods.
  • Avoid fried, oily, or very spicy foods, as these may upset your child’s stomach.

Lifestyle measures:

  • Ensure your child gets adequate rest and sleep to support recovery.
  • Remind your child to cover their mouth when they cough or sneeze to help stop the infection from spreading.
  • Keep the home well-ventilated by keeping windows open to let in fresh air and sunlight.
  • Encourage light physical activity only if the child feels well and as advised by the doctor.
  • Make sure your child completes the full course of treatment without missing any doses, as advised by the doctor, for complete recovery.

Have a query?

How Soon It Starts Working

  • The time required for Macox-Plus Kid Tablet to start to work: Macox-Plus Kid Tablet ideally starts to work within a few minutes after administration.
  • The time for which the effects of Macox-Plus Kid Tablet last: The effects of Macox-Plus Kid Tablet usually last for about 24 hours.

What if you forget to take Macox-Plus Kid Tablet

If you miss administering a dose, give it to your child as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not double the dose.

Drug Warnings

  • Do not give Macox-Plus Kid Tablet if your child is allergic to any of its ingredients or has active liver disease or drug-induced liver disease.
  • Inform the doctor if your child has kidney or liver problems, diabetes, seizures, HIV infection, or a history of gout before starting treatment.
  • Macox-Plus Kid Tablet may cause liver damage, so consult the doctor if your child experiences symptoms such as loss of appetite, nausea, vomiting, yellowing of the eyes (jaundice), dark urine, abdominal pain, or persistent tiredness for more than 3 days.
  • Consult a doctor if your child develops flu-like symptoms, such as headache, fever, or muscle aches, while taking Macox-Plus Kid Tablet .
  • Let your doctor know about any medicines, including vitamins or herbal supplements, your child is taking, to avoid any side effects or interactions.

Drug-Drug Interactions

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Drug-Drug Interactions: Macox-Plus Kid Tablet may interact with certain medicines, potentially increasing side effects or altering their effectiveness. Inform your doctor if your child is taking any of the following medications:

  • Anticancer drugs (Regorafenib)
    Potential effect: May increase the blood levels of Regorafenib, leading to side effects.
  • Lipid-lowering agents (Lovastatin)
    Potential effect: May increase the risk of myopathy (muscle problems), including rhabdomyolysis (a condition that causes muscle breakdown).
  • Antifungal drugs (Voriconazole)
    Potential effect: May increase the blood levels of Voriconazole.
  • Anti-HIV drugs (Darunavir, Indinavir)
    Potential effect: May decrease the blood levels and effects of anti-HIV drugs.
  • Antianginal drugs (Ranolazine)
    Potential effect: May reduce the blood levels and effects of Ranolazine.
  • Antiulcer drugs (Omeprazole)
    Potential effect: May increase the blood levels and effects of Omeprazole, leading to side effects.
  • Drugs used to stop or slow the progression of fibrosis (Pirfenidone)
    Potential effect: May reduce the blood levels and effects of Pirfenidone.

Drug-Food Interactions: Avoid giving any foods containing histamine or tyramine, such as cured meats, aged cheese, soya, tuna, salmon, and mackerel, to your child while taking Macox-Plus Kid Tablet to prevent adverse reactions.

Drug-Disease Interactions: Macox-Plus Kid Tablet should be avoided or used with caution in children with:

  • Liver problems, such as active liver disease or drug-induced liver injury
  • Kidney problems
  • Peripheral neuropathy (nerve damage causing tingling or numbness in hands and feet)
  • Blood-related problems affecting blood cell production
  • Porphyria (a rare inherited disorder)
  • HIV infection

Drug-Drug Interactions

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How does the drug interact with Macox-Plus Kid Tablet:
Taking darunavir with Macox-Plus Kid Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Taking voriconazole with Macox-Plus Kid Tablet can increase the risk of infections.

How to manage the interaction:
Although there is an interaction between voriconazole and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Taking ranolazine with Macox-Plus Kid Tablet can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Taking indinavir with Macox-Plus Kid Tablet can reduce the blood levels and effects of indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Macox-Plus Kid Tablet:
Taking saquinavir with Macox-Plus Kid Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Macox-Plus Kid Tablet:
Co-administration of halofantrine with Macox-Plus Kid Tablet can increase the blood levels of halofantrine, which increases the risk of abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Macox-Plus Kid Tablet and halofantrine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Taking Macox-Plus Kid Tablet with cefazolin can increase the risk of side effects that can cause bleeding complications.

How to manage the interaction:
Although there is an interaction between Macox-Plus Kid Tablet and cefazolin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Taking deflazacort with Macox-Plus Kid Tablet may reduce the blood levels and effects of deflazacort.

How to manage the interaction:
Although there is an interaction between deflazacort and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Coadministration of gefitinib with Macox-Plus Kid Tablet can decrease the blood levels and effects of gefitinib.

How to manage the interaction:
Although there is an interaction between gefitinib and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macox-Plus Kid Tablet:
Taking dabigatran etexilate with Macox-Plus Kid Tablet can decrease the blood levels and effects of dabigatran etexilate.

How to manage the interaction:
Although there is an interaction between dabigatran etexilate and Macox-Plus Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

Macox-Plus Kid Tablet is used to prevent and treat tuberculosis in children who weigh less than 25 kg.

Macox-Plus Kid Tablet contains Rifampicin and Isoniazid, which work together to kill the bacteria that cause tuberculosis (TB). They stop the bacteria from growing and spreading, helping the body fight and clear the infection.

Macox-Plus Kid Tablet may cause a reddish-orange discolouration of body fluids such as tears, sputum, and urine. This is harmless and usually does not require treatment. However, speak to your doctor if you have any concerns.

Common side effects of Macox-Plus Kid Tablet may include nausea, vomiting, diarrhoea, stomach pain, loss of appetite, itching, and tingling or numbness of the skin. However, these symptoms usually resolve as your body adjusts to the medication. If these side effects persist or worsen, please consult a doctor.

Macox-Plus Kid Tablet contains isoniazid, which may interact with foods and drinks containing histamine or tyramine, such as cured meats, aged cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid giving these foods while your child is taking this medicine.

Macox-Plus Kid Tablet may affect the results of some blood tests, such as folate, vitamin B12, and liver function tests. Inform the person doing the tests that your child is taking Macox-Plus Kid Tablet .

Macox-Plus Kid Tablet is composed of two antimycobacterial drugs, Rifampicin and Isoniazid. It is used to treat and prevent tuberculosis in children.

If you forget to give a dose of Macox-Plus Kid Tablet to your child, give it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and give the next one at the usual time. Do not give two doses together, as this may increase the risk of side effects.

The best time to give Macox-Plus Kid Tablet is on an empty stomach, at least 1 hour before or 2 hours after a meal. This helps the body absorb the medicine more effectively.

Macox-Plus Kid Tablet is generally considered safe for children when used exactly as prescribed by a doctor. However, like all medicines, it may cause side effects or interact with other drugs. It is important to follow the doctor’s instructions carefully and to inform them of your child’s medical history and any other medicines they are taking to avoid potential complications.

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0006
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