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  3. Lupilyzer Oral Solution 200 ml

Lupilyzer Oral Solution 200 ml, Pack of 1 Solution
Lupilyzer Oral Solution 200 ml, Pack of 1 Solution
Lupilyzer Oral Solution 200 ml, Pack of 1 Solution
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lupilyzer Oral Solution is used to treat renal tubular acidosis and kidney stones. It contains Magnesium citrate and Potassium citrate which prevents the crystallisation, growth and accumulation of stone-forming salts. In some cases, this medicine may cause side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

MAGNESIUM CITRATE-375MG + POTASSIUM CITRATE-1100MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lupilyzer Oral Solution

Lupilyzer Oral Solution is indicated for the treatment of renal tubular acidosis and kidney stones due to low citric acid levels or high uric acid. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine, this causes the blood to remain too acidic.
 
Lupilyzer Oral Solution is a combination of two drugs, namely: Magnesium citrate and Potassium citrate. Lupilyzer Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts.
 
You are advised to take Lupilyzer Oral Solution for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Lupilyzer Oral Solution if you are pregnant or breastfeeding. Lupilyzer Oral Solution is not recommended for children as safety and effectiveness have not been established. It is not known if alcohol interacts with Lupilyzer Oral Solution , so please consult a doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Lupilyzer Oral Solution

Lupilyzer Oral Solution is used in the treatment of kidney stones, renal tubular acidosis. The detailed uses of Lupilyzer Oral Solution are as follows:

  • Kidney Stone Prevention: Lupilyzer Oral Solution is often used to help dissolve and prevent the formation of kidney stones by reducing the concentration of stone-forming substances in the urine.
  • Kidney health: Lupilyzer Oral Solution supports kidney health by maintaining proper mineral balance.
  • Relief from Pain: Lupilyzer Oral Solution may provide relief from pain associated with urinary stones by alleviating discomfort during urination and reducing spasms in the urinary tract.
  • Renal Tubular Acidosis: Lupilyzer Oral Solution contains Magnesium Citrate and Potassium Citrate, which help increase urinary pH, reducing acidity.

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Directions for Use

  • Lupilyzer Oral Solution can be taken after meals or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions before use.
  • Mix the advised dose of Lupilyzer Oral Solution with a glass of water as directed and take it orally.
  • Shake the bottle well before use.

Medicinal Benefits

Lupilyzer Oral Solution is a combination of two drugs, namely: Magnesium citrate and Potassium citrate. Lupilyzer Oral Solution is indicated for the treatment of renal tubular acidosis with calcium stones, uric acid lithiasis with or without calcium stone, hypocitraturic calcium oxalate nephrolithiasis (kidney stones). Lupilyzer Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts. 

How Lupilyzer Oral Solution Works

Lupilyzer Oral Solution is a combination of two drugs, namely: Magnesium citrate and Potassium citrate. Lupilyzer Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation, growth and accumulation of stone-forming salts.

Storage

• Store in a cool and dry place away from sunlight.• Keep Lupilyzer Oral Solution out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Lupilyzer Oral Solution 200 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

What if I have taken an overdose of Lupilyzer Oral Solution

Take Lupilyzer Oral Solution only as advised by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Lupilyzer Oral Solution if you are allergic to any of its components; if you have hyperkalaemia (high levels of potassium), delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infection, or renal insufficiency. Inform your doctor if you have gastrointestinal lesions. If you experience severe vomiting, gastrointestinal bleeding or abdominal pain, stop taking Lupilyzer Oral Solution and consult a doctor immediately. Lupilyzer Oral Solution is not recommended for children as safety and effectiveness have not been established. Consult your doctor before taking Lupilyzer Oral Solution if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Potassium citrateDisopyramide
Critical
Potassium citrateOrphenadrine (chloride)
Critical

Drug-Drug Interactions

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Potassium citrateDisopyramide
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Disopyramide and Lupilyzer Oral Solution 200 ml together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Although taking Disopyramide and Lupilyzer Oral Solution 200 ml together is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOrphenadrine (chloride)
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Orphenadrine and Lupilyzer Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Orphenadrine (chloride) with Lupilyzer Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateOrphenadrine (citrate)
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Orphenadrine and Lupilyzer Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Orphenadrine (citrate) with Lupilyzer Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateDimenhydrinate
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Co-administration of Dimenhydrinate and Lupilyzer Oral Solution 200 ml can increase the risk of developing stomach inflammation.

How to manage the interaction:
Taking Dimenhydrinate with Lupilyzer Oral Solution 200 ml is generally avoided, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, sudden lightheadedness, vomiting (especially with blood), or tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateDoxepin
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Doxepin and Lupilyzer Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Doxepin with Lupilyzer Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, consult the doctor immediately if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools. Do not discontinue any medications without a doctor's advice.
Potassium citrateMesoridazine
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Mesoridazine and Lupilyzer Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Lupilyzer Oral Solution 200 ml with Mesoridazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateDiphenhydramine
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Diphenhydramine and Lupilyzer Oral Solution 200 ml together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Diphenhydramine with Lupilyzer Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citrateTrihexyphenidyl
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Co-administration of trihexyphenidyl with Lupilyzer Oral Solution 200 ml may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking trihexyphenidyl with Lupilyzer Oral Solution 200 ml is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium citratePhenindamine
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Phenindamine and Lupilyzer Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Phenindamine with Lupilyzer Oral Solution 200 ml is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium citratePropantheline
Critical
How does the drug interact with Lupilyzer Oral Solution 200 ml:
Taking Propantheline and Lupilyzer Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Propantheline with Lupilyzer Oral Solution 200 ml is not recommended, as it may lead to interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.

  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.

  • Maintain a healthy weight by exercising regularly.

  • Avoid foods rich in oxalates such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potato, french fries, and cereals as they might increase the risk of oxalate stones.

  • Try maintaining optimum levels of calcium in the body as too little or high calcium can lead to kidney stones.

Habit Forming

No

Therapeutic Class

RENAL AND GENITOURINARY AGENT
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Alcohol

Caution

It is not known if alcohol interacts with Lupilyzer Oral Solution . Please consult a doctor.

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Pregnancy

Caution

Lupilyzer Oral Solution belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Lupilyzer Oral Solution ; your doctor will decide whether Lupilyzer Oral Solution can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Lupilyzer Oral Solution is unlikely to affect your ability to drive. However, you are advised to drive only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Lupilyzer Oral Solution in patients with hepatic impairment. Please consult your doctor.

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Kidney

Unsafe

Lupilyzer Oral Solution might cause soft tissue calcification and hyperkalaemia in patients with renal insufficiency. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

The safety and effectiveness of Lupilyzer Oral Solution in children have not been established.

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Heart

Lupilyzer Oral Solution should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Lupilyzer Oral Solution .

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Geriatrics

Caution

Lupilyzer Oral Solution should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Lupilyzer Oral Solution .

FAQs

Lupilyzer Oral Solution contains Magnesium citrate and Potassium citrate. Lupilyzer Oral Solution raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation of stone-forming salts.

To treat your condition effectually, continue taking Lupilyzer Oral Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Lupilyzer Oral Solution .

Avoid taking Lupilyzer Oral Solution if you have peptic ulcers as Lupilyzer Oral Solution has ulcerogenic potential, which could lead to further ulceration.

Diarrhoea might be a side-effect of Lupilyzer Oral Solution . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Consult a doctor before taking Lupilyzer Oral Solution if you have an active urinary tract infection, as Lupilyzer Oral Solution increases the urinary pH, which might promote further bacterial growth.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - LUP0284

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:28 AM IST

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Reference

  1. https://www.ciplamed.com/content/ston1-oral-solution
  2. https://www.drugs.com/mtm/potassium-citrate.html

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