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compositionComposition:IRON-12MG
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Lupiheme Tablet is used to treat iron deficiency anaemia. It contains Iron, which aids the formation of red blood cells to carry oxygen to other body cells and tissues. In some cases, this medicine may cause side effects such as constipation, diarrhoea, stomach cramps, dark stools, loss of appetite, and upset stomach. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IRON-12MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lupiheme Tablet

Lupiheme Tablet is primarily taken to treat or prevent low levels of red blood cells in the blood, a condition often associated with fatigue and weakness. It serves a vital medical purpose by helping your body produce haemoglobin, the essential protein that carries oxygen from your lungs to the rest of your organs and tissues.

To achieve the best results, this medicine is typically taken daily or as directed by your healthcare provider, and consistency is key to restoring your body's natural reserves. For optimal absorption, it is best to take it on an empty stomach, though you can take it with food if it causes stomach irritation. Incorporating simple dietary adjustments, such as eating foods high in Vitamin C, can also significantly help your body absorb this medicine more efficiently.

While taking Lupiheme Tablet , some people may experience mild, manageable side effects like dark stools or mild constipation. However, you should consult your doctor immediately if you experience severe symptoms, such as sharp stomach pain, chest pain, or signs of an allergic reaction.

Before starting this medicine, you must talk to your doctor if you have specific pre-existing health conditions. Do not take this if you have conditions associated with excess mineral build-up, have had frequent blood transfusions, or suffer from severe stomach ulcers.

Additionally, Lupiheme Tablet can interact with certain substances; for instance, taking it alongside antacids or specific antibiotics can stop it from working properly. If you are pregnant, breastfeeding, planning a pregnancy, or are an older adult, consult your doctor to ensure you are taking the safest and most appropriate dose for your needs.

Uses of Lupiheme Tablet

Lupiheme Tablet is used to treat or prevent low levels of red blood cells in the blood. The detailed uses of Lupiheme Tablet are as follows:

  • Anaemia caused by low mineral levels: Lupiheme Tablet helps by replenishing the body's natural stores of this essential nutrient, which is required to build healthy red blood cells and restore overall energy.
  • Red blood cell support during pregnancy: Lupiheme Tablet helps meet the increased demand for blood volume and oxygen transport, supporting both maternal health and fetal development.
  • Dietary deficiency: Lupiheme Tablet helps restore normal blood levels in individuals who do not get a sufficient amount of this key nutrient from their daily diet alone.

Key Benefits

Lupiheme Tablet helps restore healthy red blood cell levels, improving oxygen delivery throughout the body and supporting overall health. With regular use, it helps boost energy, enhances mental performance, and promotes healthier skin, hair, and nails.

  • Boosts Energy and Reduces Fatigue: By helping your body produce more red blood cells, this medicine improves oxygen flow to tissues, reducing tiredness and helping you feel more active, alert, and physically capable.
  • Improves Focus and Mental Clarity: Better oxygen delivery to the brain helps reduce cognitive fog, supporting improved concentration, memory, and overall productivity.
  • Supports Healthy Skin, Hair, and Nails: By restoring essential nutrient levels needed for healthy red blood cell production, this medicine helps improve pale skin, brittle nails, and hair thinning associated with depleted red blood cell counts.
Side effects of Lupiheme Tablet
  • Frequent flossing and brushing can help remove bacteria and debris that can give your teeth a metallic taste.
  • The metallic flavor may be caused by a zinc deficiency. Eat foods like meat, chicken, and oysters that are high in zinc.
  • Reducing the intake of foods with strong aromas, like onions and garlic, as they may intensify the taste of metallic substances.
  • Avoid smoking and tobacco products as they may intensify the metallic flavor.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Lupiheme Tablet can be taken with or without food, as advised by the physician.
  • Take Lupiheme Tablet at the same time each day to maintain consistency and get the best results.
  • Swallow Lupiheme Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Lupiheme Tablet Works

Lupiheme Tablet contains iron, which works by supplying the key building block that your body needs to manufacture haemoglobin. Haemoglobin is the protein inside your red blood cells that binds to oxygen in your lungs and carries it to your tissues and organs. When your body does not have enough of this key nutrient, it cannot produce sufficient haemoglobin, leading to oxygen deprivation in the tissues, which causes fatigue and weakness. When you take Lupiheme Tablet , it is absorbed through your digestive tract and directly utilised by your bone marrow to create new, healthy red blood cells. Over time, this process replenishes your body's internal storage depots, restoring normal oxygen distribution, enhancing physical stamina, and reversing the symptoms associated with depleted blood levels.
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Alcohol

Caution

It is advised to avoid alcohol intake while using Lupiheme Tablet since alcohol can hinder the absorption of iron in Lupiheme Tablet .

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Pregnancy

Consult your doctor

Lupiheme Tablet is safe to use if advised by a doctor during pregnancy. Lupiheme Tablet is generally given at least four weeks before pregnancy and is continued up to 3 months of pregnancy.

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Breast Feeding

Caution

Lupiheme Tablet can pass into the breast milk when used by a breastfeeding mother. Please consult your doctor before taking Lupiheme Tablet if you are a nursing mother

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Driving

Safe

Lupiheme Tablet does not affect your ability to drive or operate any machinery. If you notice any side effects that affect your mental ability while using Lupiheme Tablet , please consult your doctor.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Lupiheme Tablet .

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Kidney

Caution

It is advised to seek doctor advice before starting Lupiheme Tablet if you have kidney diseases.

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Children

Consult your doctor

The doctor will decide the dosage of Lupiheme Tablet based on the child's age and weight.

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Heart

Consult your doctor

Consult your doctor if you have a history of heart disease. Your doctor will recommend only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Lupiheme Tablet should be given to elderly patients only if recommended by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Lupiheme Tablet

In case of an accidental overdose, seek emergency medical attention immediately. An overdose of this mineral can be highly toxic, especially to young children, and requires urgent medical intervention.

Diet & Lifestyle Advise

  • Eat foods rich in Vitamin C, such as oranges, strawberries, bell peppers, and broccoli, alongside your dose to help your body absorb Lupiheme Tablet more effectively.
  • Avoid consuming dairy products, eggs, tea, coffee, or high-fibre foods within two hours of taking your medication, as these can block its absorption.
  • Drink plenty of water and maintain a fibre-rich diet to help prevent or ease the constipation that frequently occurs with this supplement.
  • Incorporate naturally nutrient-rich foods into your diet, including lean meats, poultry, beans, lentils, and dark leafy green vegetables, to support healthy blood production.

Health Queries

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Can my symptoms of constant tiredness, dizziness, lightheadedness, and seeing spots of light still be caused by other abnormal results on my blood test even if my hemoglobin level is normal, and is that why I was prescribed Lupiheme?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Yes, even if your hemoglobin level is normal, you can still have low iron stores (ferritin), which can cause these exact symptoms. This is likely why you were prescribed Lupiheme, which is an iron supplement to help rebuild your iron reserves. Other abnormal blood results, such as low vitamin levels or thyroid imbalances, can also contribute to your symptoms. Please feel reassured that addressing these underlying levels can help you feel much better.

Is it safe for a 24-year-old with a very low blood count (hemoglobin level of 7.5) to take Lupiheme tablets?

Vikas Singh

Vikas Singh

M Pharmacy

Yes, it is generally safe and very common to take an iron supplement like Lupiheme for a hemoglobin level of 7.5, which indicates moderate anemia. Lupiheme helps your body rebuild its red blood cells. However, because a level of 7.5 is quite low, it is very important to consult a healthcare provider right away. They will help identify the underlying cause of the anemia, prescribe the correct dosage, and monitor your recovery. Please be reassured that this is a highly treatable condition, and with the right guidance, your energy and health will steadily improve.

What should I do if my hemoglobin (blood) levels have dropped from 9.5 to 8.6 after taking Lupiheme tablets for a month?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

It can be concerning to see your hemoglobin levels drop from 9.5 to 8.6 after a month on Lupiheme (iron) tablets, but please try not to worry. Sometimes, oral iron is not absorbed well, or there might be an ongoing cause for the drop, such as heavy menstrual bleeding. I highly recommend consulting your doctor soon. They can run simple tests, like checking your ferritin levels, to find the exact cause and safely adjust your treatment. Please continue taking your medication as prescribed until you speak with them.

Can I crush my Lupiheme tablet for low iron if it is too big for me to swallow?

Vikas Singh

Vikas Singh

M Pharmacy

I completely understand how difficult it can be to swallow large tablets. I recommend not crushing your Lupiheme (heme iron polypeptide) tablet. Crushing iron tablets can cause stomach irritation, reduce how well your body absorbs the medicine, and even stain your teeth. Since you are taking this to help your iron levels, we want to ensure you get the full benefit comfortably. Please speak with your doctor or pharmacist about alternative options, such as a liquid iron supplement or smaller capsules that are easier to swallow. There are many great alternatives available to help you!

Do ALL9NVP and LUPIHEME tablets have the same ingredients, and can they be taken on the same day?

Veda Maddala

Veda Maddala

M Pharmacy

To answer your question, ALL9NVP and LUPIHEME do not have the same ingredients. ALL9NVP contains essential B-vitamins (L-methylfolate, pyridoxal-5-phosphate, and methylcobalamin), while LUPIHEME contains heme iron polypeptide. Because they contain different and complementary nutrients, you can safely take them on the same day. In fact, they are often paired together to help support your blood health and energy levels. I recommend taking them as directed by your healthcare provider.

Can I take Lupiheme and Polybion CZS tablets together at the same time?

Vikas Singh

Vikas Singh

M Pharmacy

Yes, you can safely take Lupiheme (heme iron polypeptide) and Polybion CZS (vitamin B-complex with zinc and vitamin C) together. There are no harmful interactions between them. In fact, the vitamin C in Polybion CZS actually helps your body absorb the iron in Lupiheme much better! To prevent any mild stomach upset, it is best to take them with a meal. If you prefer, you can also space them out?taking one with breakfast and the other with lunch.
health query

Have a query?

How Soon It Starts Working

  • The time required for Lupiheme Tablet to start to work: The time required for Lupiheme Tablet to show its action is unknown.
  • The time for which the effects of Lupiheme Tablet last: The duration of action for Lupiheme Tablet is clinically unknown.

Storage

• Store Lupiheme Tablet at a controlled room temperature, strictly between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original container, tightly closed, and stored in a dry place away from direct sunlight and moisture.

What if you forget to take Lupiheme Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Always check the product packaging before use to ensure the tablets or liquid have not changed in appearance, colour, or consistency.
  • If you are taking a liquid form of Lupiheme Tablet , mix it with water or juice and drink it through a straw to prevent the liquid from temporarily staining your teeth.
  • Do not take antacids, calcium supplements, or daily multivitamins within two hours of taking Lupiheme Tablet , as they can significantly lower its effectiveness.
  • Inform any healthcare professional treating you, including dentists, that you are taking Lupiheme Tablet , as it can occasionally interfere with certain medical tests.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain Antibiotics and Thyroid Medicines: Lupiheme Tablet may reduce the absorption and effectiveness of certain antibiotics, such as tetracyclines and fluoroquinolones, as well as thyroid medicines like levothyroxine. To minimise this interaction, take these medicines at least 2 hours before or after taking Lupiheme Tablet .
    Acid-Reducing Medicines: Antacids, H2 blockers, and proton pump inhibitors can reduce the absorption of the active mineral in Lupiheme Tablet , making it less effective. Your doctor may advise adjusting the timing of these medicines or recommend an alternative treatment.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Dairy Products, Eggs, Tea, Coffee, and Whole Grains: These foods and beverages contain compounds that can bind to the active mineral in Lupiheme Tablet and reduce its absorption. To help your body absorb the medicine properly, avoid consuming them at the same time as your dose.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Lupiheme Tablet belongs to a class of haematinics; primarily used to treat iron deficiency and anaemia (deficiency of iron and haemoglobin).
Lupiheme Tablet is a dietary supplement that contains Iron. It works by boosting the production of red blood cells (RBC) in the body, thus treating iron deficiency-associated anaemia.
It is recommended not to take Lupiheme Tablet along with tea, coffee, or milk, and eggs since they might interfere with iron absorption from Lupiheme Tablet .
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage. Do not double the dose.
Iron is best absorbed if taken on an empty stomach. However, in some patients, Lupiheme Tablet may cause gastrointestinal disturbances, such as stomach upset, when taken without food. So, please take it as suggested by your doctor if you have stomach problems.
Lupiheme Tablet may cause constipation as one of its side effects. Eating fibre-rich foods like vegetables, fresh fruits, and cereals, and drinking plenty of water can help relieve symptoms.
Antacids may interfere with the absorption of iron. Hence, it is advised to take Lupiheme Tablet two hours before, or four hours after taking antacids.
No, you should avoid taking Lupiheme Tablet with coffee or tea. These beverages contain compounds that can significantly reduce how much of the medicine your body absorbs. It is best to wait at least two hours after taking your medicine before enjoying these drinks. Talk to your doctor or pharmacist if you need help planning your daily routine.
Having dark or black-colored stools is a very common and completely harmless occurrence. It simply means your body is naturally eliminating the portion of the mineral that it did not absorb. However, if your stools are sticky, tarry, or accompanied by severe stomach pain, talk to your doctor immediately.
Yes, Lupiheme Tablet is very commonly suggested during pregnancy to support the increased blood supply needed for both the mother and baby. However, you should only take the specific dose recommended by your healthcare provider. Talk to your doctor to determine the appropriate amount for your pregnancy.
No, you should swallow the tablets whole. Crushing, chewing, or breaking them can cause too much of the medicine to be released at once, which increases the risk of stomach irritation and can stop it from absorbing properly. If you find it hard to swallow tablets, talk to your doctor or pharmacist about switching to a liquid form.
Constipation is a common side effect of this medication. You can manage it by increasing your daily water intake and eating more high-fibre foods. If the issue persists or becomes severe, talk to your doctor or pharmacist before taking any laxatives.
It is generally best to separate them. Many multivitamins contain calcium or other minerals that can compete with Lupiheme Tablet , making it less effective. Try to space them at least two hours apart, and talk to your doctor or pharmacist to help organise your supplement schedule.
No, there is no clinical evidence to suggest that taking Lupiheme Tablet directly causes weight gain. If you notice any unexpected changes in your weight while taking this medication, talk to your doctor to identify the underlying cause.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Ferrous Sulfate Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Iron dextran injection [Prescribing Information]. 2021. [Accessed on 10 Jun. 2025]Check here
  4. Iron Sucrose Injection [Summary of Product Characteristics]. 2024. [Accessed on 10 Jun. 2025]Check here
  5. Venofer (iron sucrose) 20 mg iron / ml, solution for injection or concentrate for solution for infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 31 Oct 2025]Check here
  6. Venofer (iron sucrose) 20 mg iron / ml, solution for injection or concentrate for solution for infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 31 Oct 2025]Check here
  7. Drugs H. Iron Sucrose Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [Accessed on 31 Oct 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - LUP0268

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