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Lupi D3 Mouth Melt Granules used to prevent/treat vitamin D deficiency. It contains Cholecalciferol, which increases vitamin D levels in the body. In some cases, this medicine may cause side effects such as vomiting, nausea, constipation, and increased calcium levels in blood and urine. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CHOLECALCIFEROL-60000IU

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Lupi D3 Mouth Melt Granules

Lupi D3 Mouth Melt Granules is a supplement in granule form used to treat and prevent vitamin D deficiency. It helps your body absorb calcium, which is essential for building and maintaining strong bones. Doctors commonly prescribe this medicine for people who do not get enough vitamin D from their diet or sunlight.

For the best results, you should take Lupi D3 Mouth Melt Granules consistently as directed by your doctor, which is often once a week or once a month depending on your levels. It is highly recommended to take this medicine with a main meal, as dietary fats help your body absorb the vitamin much better. Combining this supplement with a balanced diet rich in calcium and regular weight-bearing exercise will further support your bone health.

Most people tolerate Lupi D3 Mouth Melt Granules very well, but some may experience mild side effects like nausea, constipation, or an upset stomach. If you develop any unusual symptoms, such as severe muscle pain, weakness, or a metallic taste in your mouth, you should consult your doctor immediately.

Before taking Lupi D3 Mouth Melt Granules , tell your doctor if you have high calcium levels in your blood or urine, kidney stones, or serious kidney disease. Do not take this if you have a known allergy to any of its ingredients or if you have hypercalcemia (too much calcium in your blood).

Certain medicines, like weight-loss drugs or cholesterol-lowering medications, can interfere with how your body absorbs Lupi D3 Mouth Melt Granules . If you are pregnant, breastfeeding, or an older adult, talk to your doctor first to ensure you are taking the correct, safe amount.

Uses of Lupi D3 Mouth Melt Granules

Lupi D3 Mouth Melt Granules is used to treat and prevent conditions caused by low vitamin D levels and to support healthy bones and calcium balance. It may be suggested for the following conditions:

  • Vitamin D deficiency: Lupi D3 Mouth Melt Granules helps restore low levels of vitamin D in the body, restoring normal bone mineralisation and immune support.
  • Osteoporosis: This medicine assists in the absorption of calcium, which helps strengthen weak, brittle bones and reduces the risk of fractures.
  • Osteomalacia or Rickets: It provides the essential nutrient needed to soften and strengthen bones in adults and children experiencing bone softening.
  • Latent tetany: It helps maintain stable calcium levels in the blood, preventing painful muscle spasms and cramps caused by low calcium.

Key Benefits

Lupi D3 Mouth Melt Granules provides several benefits by restoring vitamin D levels and improving calcium utilisation in the body. These include:

  • Supports strong bones: Improves calcium absorption to help build, maintain, and strengthen healthy bones.
  • Improves muscle function: Helps reduce muscle weakness, aches, and cramps associated with vitamin D deficiency while supporting better muscle strength.
  • Promotes healthy movement: Supports joint function and balance, helping reduce the risk of falls and fractures, particularly in older adults.
  • Maintains overall health: Restoring healthy vitamin D levels supports normal bone mineralisation, calcium balance, and overall wellbeing.
Side effects of Lupi D3 Mouth Melt Granules 1.3 gm
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Frequent flossing and brushing can help remove bacteria and debris that can give your teeth a metallic taste.
  • The metallic flavor may be caused by a zinc deficiency. Eat foods like meat, chicken, and oysters that are high in zinc.
  • Reducing the intake of foods with strong aromas, like onions and garlic, as they may intensify the taste of metallic substances.
  • Avoid smoking and tobacco products as they may intensify the metallic flavor.
  • Rest the injured area to promote healing.
  • Use heat pack for chronic pain and cold pack for recent injuries.
  • After pain decreases, do gentle stretches and light exercises.
  • Maintain good posture, eat a calcium- and vitamin D-rich diet, stay hydrated, and manage stress.
  • Seek medical help for severe or unexplained pain or if it worsens.

Directions for Use

  • Lupi D3 Mouth Melt Granules can be taken with or without food. However, it is best to take it after meals, especially with high-fat foods, for better absorption.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Dissolve Lupi D3 Mouth Melt Granules in a glass of water, stir well, and consume it immediately.
  • Do not store the prepared solution.
  • Do not touch the granules with wet hands.

How Lupi D3 Mouth Melt Granules Works

Lupi D3 Mouth Melt Granules contains cholecalciferol, also known as vitamin D3, which helps maintain healthy bones, teeth, and muscles by improving the body's ability to absorb calcium and phosphorus. Lupi D3 Mouth Melt Granules is absorbed through the digestive tract and converted by the liver and kidneys into its active form. This active form helps the intestines absorb calcium and phosphorus more efficiently from the food you eat. These minerals are essential for building and maintaining strong bones and teeth. By maintaining healthy calcium and phosphorus levels in the bloodstream, Lupi D3 Mouth Melt Granules supports normal bone mineralisation, muscle function, and overall skeletal health. It also helps prevent or treat vitamin D deficiency and its associated complications. Together, these actions help strengthen bones, support healthy muscle function, and maintain adequate vitamin D and calcium levels in the body.
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, it is advised to limit the alcohol intake while using Lupi D3 Mouth Melt Granules .

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Pregnancy

Consult your doctor

Use higher doses of Lupi D3 Mouth Melt Granules during pregnancy than the daily dietary allowance only when the doctor advises. Your physician will weigh the potential risks and benefits before recommending Lupi D3 Mouth Melt Granules .

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Breast Feeding

Consult your doctor

Consult your physician before taking Lupi D3 Mouth Melt Granules if you are breastfeeding. Lupi D3 Mouth Melt Granules can pass into the breast milk. If Lupi D3 Mouth Melt Granules is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.

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Driving

Consult your doctor

Do not drive or operate machinery if you experience dizziness while using Lupi D3 Mouth Melt Granules . Please consult your doctor if you experience any dizziness.

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Liver

Consult your doctor

Before taking Lupi D3 Mouth Melt Granules , let your physician know if you have any history of liver disease. Hepatic impairment/liver disease can alter certain Vitamin D forms' metabolic and therapeutic activity.

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Kidney

Caution

It is advised to seek physician advice before starting Lupi D3 Mouth Melt Granules if you have kidney diseases like kidney stones or undergoing dialysis. Caution should be taken in dialysis patients to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Caution

The physician will suggest the dosage of Lupi D3 Mouth Melt Granules based on the child's age and weight.

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Heart

Caution

Please inform your doctor if you have heart problems before taking Lupi D3 Mouth Melt Granules , as there is limited information available on its safety in such cases.

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Geriatrics

Caution

Lupi D3 Mouth Melt Granules is generally safe for geriatric use. However, older adults should consult a doctor to ensure proper dosage and avoid potential issues like high calcium levels or drug interactions.

What if I have taken an overdose of Lupi D3 Mouth Melt Granules

Taking too much of this supplement can lead to harmful levels of calcium build-up in your body. If you suspect an overdose, or if someone has accidentally swallowed too many granules, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Eat calcium-rich foods: Support your therapy by including dairy products (milk, cheese, yoghurt), leafy green vegetables, and calcium-fortified foods in your daily meals.
  • Get safe sun exposure: Spend 10 to 15 minutes in midday sunlight a few times a week, as sunlight triggers natural vitamin D production in your skin.
  • Stay hydrated: Drink plenty of water daily to help protect your kidneys and reduce the risk of kidney stones while taking calcium-regulating supplements.
  • Engage in weight-bearing exercise: Regular activities like walking, jogging, or resistance training work alongside this medicine to keep your bones strong and dense.
health query

Have a query?

How Soon It Starts Working

The time required for Lupi D3 Mouth Melt Granules to start to work: The time required for Lupi D3 Mouth Melt Granules to show its action is unknown. 

The time for which the effects of Lupi D3 Mouth Melt Granules last: The duration of action for Lupi D3 Mouth Melt Granules is unknown.

Storage

• Store Lupi D3 Mouth Melt Granules granules at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

What if you forget to take Lupi D3 Mouth Melt Granules

If you miss a dose of Lupi D3 Mouth Melt Granules , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Check the expiry date: Always verify the expiry date on the sachet before use and do not take expired granules.
  • Inspect the packaging: Ensure the sachet is sealed, dry, and undamaged before opening. Discard any torn or damaged sachets.
  • Do not share your medicine: Never give this vitamin D supplement to others, even if they have similar symptoms or are suspected to have low vitamin D levels.
  • Attend regular blood tests: Have your blood calcium and vitamin D levels checked as recommended by your doctor to monitor your response to treatment.
  • Inform your healthcare providers: Tell your doctor, dentist, or other healthcare professionals that you are taking a high-dose vitamin D supplement before undergoing any medical tests or procedures.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Lupi D3 Mouth Melt Granules and may require closer monitoring or dose adjustments:

  • Thiazide diuretics: Taking these medicines together may increase the risk of developing high blood calcium levels (hypercalcaemia).
  • Bile acid sequestrants (such as cholestyramine) or weight-loss medicines (such as orlistat): These medicines can reduce the absorption of Lupi D3 Mouth Melt Granules . They should be taken several hours apart.
  • Cardiac glycosides (such as digoxin): Excessively high calcium levels caused by vitamin D supplementation may increase the risk of serious heart rhythm disturbances.
ColecalciferolDoxercalciferol
Severe
ColecalciferolAluminium hydroxide
Severe

Drug-Drug Interactions

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ColecalciferolDoxercalciferol
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Lupi D3 Mouth Melt Granules 1.3 gm and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolAluminium hydroxide
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
The combined use of aluminum hydroxide with Lupi D3 Mouth Melt Granules 1.3 gm may increase the risk of toxicity.

How to manage the interaction:
Co-administration of Lupi D3 Mouth Melt Granules 1.3 gm with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ColecalciferolCalcitriol
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Lupi D3 Mouth Melt Granules 1.3 gm and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolCalcifediol
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Lupi D3 Mouth Melt Granules 1.3 gm and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Lupi D3 Mouth Melt Granules 1.3 gm and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Lupi D3 Mouth Melt Granules 1.3 gm and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolSucralfate
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ColecalciferolErgocalciferol
Severe
How does the drug interact with Lupi D3 Mouth Melt Granules 1.3 gm:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Lupi D3 Mouth Melt Granules 1.3 gm and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

The following foods may affect the absorption of Lupi D3 Mouth Melt Granules :

  • High-fat meals: Taking Lupi D3 Mouth Melt Granules with a meal containing healthy fats can improve its absorption. Try to take it consistently in the same way each time.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[VITAMIN D ANALOGS]

FAQs

Lupi D3 Mouth Melt Granules is used to treat Vitamin D deficiency, osteoporosis (weak and brittle bones), and rickets or osteomalacia (softening or deforming of bones due to a lack of calcium).
Lupi D3 Mouth Melt Granules contains Cholecalciferol, a form of vitamin D. Cholecalciferol (vitamin D3) is a supplement that promotes the absorption of calcium, phosphates and Vitamin A from different organs and helps maintain overall health.
Lupi D3 Mouth Melt Granules may cause common side effects like constipation, increased blood calcium levels, increased calcium levels in urine, vomiting, and nausea. These side effects do not require medical attention and gradually resolve over time. If these side effects persist, please consult your doctor immediately.
Lupi D3 Mouth Melt Granules should be used with caution in conditions like hypercalcemia, liver problems, kidney problems, heart problems, hypervitaminosis, kidney stones, phenylketonuria and diabetes.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Good sources of Vitamin D3 include Mushrooms, Cheese, Egg Yolks, Salmon Fish, Tuna Fish, Fortified Milk, Fortified Orange Juice, Fortified Cereals and Trout.
While you can take it without food, it is highly recommended to take Lupi D3 Mouth Melt Granules with a meal containing healthy fats. This significantly improves how well your body absorbs the medicine. Talk to your doctor or pharmacist if you have questions about your dosing routine.
This depends entirely on the dose your doctor has suggested. Some high-strength granules are designed to be taken once a week or once a month, while lower strengths may be daily. Always follow the specific schedule suggested by your healthcare provider.
Constipation can be a mild side effect of vitamin D supplements. You can manage this by drinking plenty of water and eating fiber-rich foods. If the constipation persists or becomes severe, talk to your doctor.
Pregnant women often require vitamin D, but taking too much can be harmful to the baby. Talk to your doctor to determine the safest and most effective dose for you and your developing baby.
Occasional, moderate alcohol consumption is generally safe, but heavy alcohol use can interfere with calcium absorption and weaken your bones. Talk to your doctor for personalised advice on lifestyle habits.
It is best to mix the granules with cold or room-temperature liquids like water, milk, or juice. High heat can potentially break down the active vitamin. If you are unsure, consult your pharmacist.
The only accurate way to check your vitamin D levels is through a simple blood test ordered by your healthcare provider. Talk to your doctor about scheduling a blood test to monitor your levels.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. MIMS Drug Reference Compendium. Colecalciferol Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Cholecalciferol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Nair, Rathish, and Arun Maseeh. Vitamin D: The "sunshine" vitamin. National library of Medicine, National center for Biotechnology information. Pubmed Central. 2012 [Accessed on 21st June 2022]Check here
  5. Labialfarma. Electronics Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 21st June 2022]Check here
  6. Drugs A. [Accessed on 02 Jun. 2026]Check here
  7. Pharma Patent Kft. Health Products Regulatory Authority (HPRA) [Revised in December 2020] [Accessed on 21st June 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - LUP0192

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