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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Leepure Tablet is used in the treatment of liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis. This medicine works by increasing the desaturase enzyme and thereby helps restore the liver's balance of saturated and unsaturated fatty acids. You may experience common side effects like headache, fatigue, diarrhoea, abdominal pain, and nausea.
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About Leepure Tablet

Leepure Tablet is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Liver diseases lead to disturbance of vital liver functions. Leepure Tablet effectively prevents multiple liver disease mechanisms and ensures the liver's protection, regeneration, and rejuvenation. 

Leepure Tablet contains Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine hydrochloride. Metadoxine restores the liver's balance of saturated and unsaturated fatty acids by increasing the desaturase enzyme. It accelerates the metabolism of the liver, restores ATP synthesis and redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine hydrochloride helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, Leepure Tablet helps in treating liver disease.

You can take Leepure Tablet with or without food. Swallow Leepure Tablet as a whole with water; do not crush or chew the tablet. You are advised to take Leepure Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Let your doctor know if you are allergic to any of the contents. Consult your doctor before taking Leepure Tablet if you are pregnant or breastfeeding. Be cautious while driving and operating machinery as it is unknown if Leepure Tablet interferes with your ability to drive. Avoid consuming alcohol along with Leepure Tablet as it could lead to further liver damage. Leepure Tablet should not be given to children unless prescribed by the doctor.

Uses of Leepure Tablet

Treatment of liver disease

Directions for Use

• Take Leepure Tablet with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Leepure Tablet as a whole with a glass of water.• Do not break, crush, or chew it.

Medicinal Benefits

Leepure Tablet is a combination of five drugs: Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine hydrochloride. Leepure Tablet is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Metadoxine restores the liver's balance of saturated and unsaturated fatty acids by increasing the desaturase enzyme. It accelerates the metabolism of the liver and the redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine and L-aspartate rejuvenate the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine hydrochloride helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, Leepure Tablet helps in treating liver disease. A single drug does not prevent multiple mechanisms; hence, Leepure Tablet effectively prevents multiple liver disease mechanisms and ensures the liver's protection, regeneration, and rejuvenation. 

How Leepure Tablet Works

Leepure Tablet contains Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine hydrochloride. Metadoxine restores the liver's balance of saturated and unsaturated fatty acids by increasing the desaturase enzyme. It accelerates the metabolism of the liver, restores ATP synthesis and redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine hydrochloride helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, Leepure Tablet helps in treating liver disease.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Leepure Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Leepure Tablet

Do not take more than the prescribed dose of Leepure Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Leepure Tablet if you are allergic to any content of Leepure Tablet . Consult your doctor before taking Leepure Tablet if you are pregnant or breastfeeding. Avoid consuming alcohol, as it could lead to further liver damage. Leepure Tablet should not be given to children unless prescribed by the doctor. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects/interactions. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Leepure Tablet:
Coadministration of Leepure Tablet and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Leepure Tablet and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
How does the drug interact with Leepure Tablet:
Trimethoprim may decrease the blood levels and effects of Leepure Tablet.

How to manage the interaction:
Although there is a possible interaction between Leepure Tablet and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with Leepure Tablet:
Sulfadiazine may decrease the blood levels and effects of Leepure Tablet.

How to manage the interaction:
Although there is a possible interaction between Leepure Tablet and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
How does the drug interact with Leepure Tablet:
Co-administration of Leepure Tablet with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Leepure Tablet and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Leepure Tablet:
Coadministration of Leepure Tablet and Carbamazepine may reduce the blood levels of Leepure Tablet.

How to manage the interaction:
Although there is a possible interaction between Leepure Tablet and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
How does the drug interact with Leepure Tablet:
Coadministration of Leepure Tablet and Cholestyramine may interfere with the absorption of Leepure Tablet.

How to manage the interaction:
Although taking Cholestyramine and Leepure Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcohol consumption and quit smoking. 
  • Maintain a healthy weight by exercising regularly.
  • Adopt a liver-friendly diet such as fibre-rich food.
  • Cut down on fats, sugar, and salt.
  • Avoid stress by practising yoga or meditation. 
  • Exercise regularly as it helps in reducing the accumulation of fat.

Habit Forming

No

Therapeutic Class

HEPATOPROTECTIVE AGENTS
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Alcohol

Unsafe

Avoid consumption of alcohol as it may lead to further liver damage.

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Pregnancy

Caution

Limited information is available regarding the usage of Leepure Tablet in pregnancy. Let your doctor know if you are pregnant before taking Leepure Tablet . your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the usage of Leepure Tablet in breastfeeding mothers. Consult your doctor before taking Leepure Tablet ; your doctor will decide whether Leepure Tablet can be taken by breastfeeding mothers.

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Driving

Caution

It is not known if Leepure Tablet interferes with your ability to drive. Do not drive or operate machines if you experience any symptoms that affect your alertness.

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Liver

Safe if prescribed

Leepure Tablet is used to treat various liver conditions. So, it is probably safe to be taken by patients with liver impairment. If you have any concerns, discuss them with your doctor.

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Kidney

Caution

Leepure Tablet is generally safe to be used in patients with kidney disease. However, please consult your doctor if you have any concerns.

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Children

Caution

Limited information is available regarding the usage of Leepure Tablet in children. Please consult your doctor.

Have a query?

FAQs

Leepure Tablet is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease).

Leepure Tablet accelerates the liver's metabolism and restores ATP synthesis and redox balance of hepatocytes. It helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. Leepure Tablet rejuvenates the liver by increasing the rate of energy production in liver cells and helps in the liver's metabolism of dietary carbohydrates and fats.

Do not discontinue Leepure Tablet without consulting your doctor. To treat your condition effectually, continue taking Leepure Tablet for as long as prescribed. Contact your doctor if you feel any difficulty while taking Leepure Tablet .

Consult your doctor before taking levodopa with Leepure Tablet as it might lower the efficacy of levodopa.

Diarrhoea could be a side-effect of Leepure Tablet . Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or find blood in your stools.

Leepure Tablet effectively prevents multiple liver disease mechanisms and ensures the liver's protection, regeneration, and rejuvenation. Thus, treats liver disease and helps in the proper functioning of the liver.

Country of origin

India

Manufacturer/Marketer address

San Diego, California
Other Info - LEE0091

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