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compositionComposition:ALPHA KETOANALOGUE
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KESTEAD XT TABLETS is used to treat chronic kidney disease. It contains Alpha Ketoanalogue, which works by lowering urea levels in the blood and improving kidney function. In some cases, this medicine may cause side effects such as increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALPHA KETOANALOGUE

Manufacturer/Marketer :

Steadfast MediShield Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About KESTEAD XT TABLETS

KESTEAD XT TABLETS is a specialised medical nutrition therapy used to manage chronic kidney disease in patients with renal impairment. It is prescribed to prevent and treat damage caused by faulty protein metabolism when kidney function is reduced. By providing essential nutrients without overloading the kidneys with toxic waste, it helps maintain overall body function.

This medication must be taken consistently every day, exactly as prescribed, to be effective in managing kidney health. You should take KESTEAD XT TABLETS during your meals to help your body process and utilise the nutrients correctly. For the best results, it is crucial to combine this treatment with a strict, low-protein diet and regular physical activity recommended by your healthcare team.

While taking KESTEAD XT TABLETS , some people may experience mild side effects, such as a slight increase in calcium levels or mild stomach upset. If you notice signs of severe calcium buildup, such as extreme muscle weakness, confusion, or severe nausea, you must consult your doctor immediately.

Before starting KESTEAD XT TABLETS , talk to your doctor if you have any existing metabolic conditions or mineral imbalances. Do not take this medicine if you already have abnormally high calcium levels in your blood or if you have a hereditary disorder that affects how your body processes amino acids.

Avoid taking this medicine at the same time as certain antibiotics or iron supplements. The calcium salts present in the tablets can bind to these medicines in the gastrointestinal tract, reducing their absorption and effectiveness. Your doctor or pharmacist may recommend spacing these medicines by at least 2 hours. If you are pregnant, breastfeeding, or an elderly individual, consult your healthcare provider to ensure this treatment is safe for your specific needs.

Description

Kestead XT Tablet is a remedy used to treat chronic renal disease in individuals undergoing conservative management therapy (CKD stage I, II, III). It aids in delaying the progression of renal disease during the pre-dialysis period when combined with a very low protein diet or a low protein diet. Kestead XT Tablet contains amino acids in the form of keto analogues, and these help improve a person's general health. Calcium-3-Methyl-2-Oxo-Valerate, Calcium-4-Methyl-2-Oxo-Valerate, Calcium-2-Oxo-3-Phenylpropionate, Calcium-3-Methyl-2-Oxo-Butyrate, Calcium-DL-2-Hydroxy-4 (methylthio) Butyrate, L-Lysine Acetate, L-Threonine, L-Tryptophan, L-Histidine and L-Tyrosine are the key components of the Kestead XT Tablet.

Uses of KESTEAD XT TABLETS

KESTEAD XT TABLETS is used to manage chronic kidney disease in patients with renal impairment. The detailed uses of KESTEAD XT TABLETS are as follows:

  • Chronic Kidney Disease (CKD): Helps delay the progression of kidney damage in patients with moderate to severe kidney disease by reducing the accumulation of toxic waste products in the blood.
  • Uremia Prevention: Helps manage and prevent symptoms caused by the buildup of nitrogen-containing waste products in the blood, which happens when kidneys cannot filter properly.

Key Benefits

KESTEAD XT TABLETS helps support nutrition in people with chronic kidney disease who are following a low-protein diet. It provides essential amino acid precursors without adding a significant nitrogen load, helping reduce the build-up of waste products in the blood.

  • Supports Nutrition on a Low-Protein Diet: KESTEAD XT TABLETS helps provide the building blocks needed for protein synthesis while helping limit the burden on the kidneys.
  • Helps Reduce Uremic Waste: By improving the use of dietary protein and reducing nitrogen waste production, KESTEAD XT TABLETS may help lower the accumulation of toxic waste products associated with kidney disease.
  • May Help Preserve Kidney Function: Better metabolic control may help support remaining kidney function and may delay the need for dialysis in appropriate patients when used as part of a prescribed kidney care plan.
  • Improves Daily Wellbeing: By supporting nutritional status, KESTEAD XT TABLETS may help reduce fatigue, muscle cramps, poor appetite, nausea, and other symptoms related to advanced kidney disease, improving overall comfort and quality of life.

Directions for Use

  • KESTEAD XT TABLETS can be taken with meals to increase absorption.
  • It is advised to take this medication three times daily or as prescribed by your doctor.
  • Swallow KESTEAD XT TABLETS as a whole with a glass of water.
  • Do not chew, crush, or break it.

How KESTEAD XT TABLETS Works

KESTEAD XT TABLETS contains alpha-ketoanalogues, which are nitrogen-free precursors of essential amino acids. After absorption, these alpha-ketoacids undergo transamination, a process in which they accept an amino (nitrogen) group from non-essential amino acids or other nitrogen-containing compounds in the body, converting into essential amino acids. This allows the body to maintain protein synthesis without introducing additional dietary nitrogen, helping reduce the production and accumulation of nitrogenous waste while supporting nutritional status and limiting the workload on the kidneys in people following a low-protein diet.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with KESTEAD XT TABLETS to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

KESTEAD XT TABLETS should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult the doctor; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Caution should be exercised, and it is advisable to consult a doctor before using it. The doctor will prescribe if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Drive only if you are physically stable and mentally focused. If you experience drowsiness after taking this medication, you should not drive or operate machinery or vehicles.

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Liver

Consult your doctor

Inform your doctor before taking KESTEAD XT TABLETS if you have a liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Safe if prescribed

KESTEAD XT TABLETS can be taken safely if prescribed. Usually, it does not affect the kidney.

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Children

Unsafe

The safety and efficacy of KESTEAD XT TABLETS in children have not been established. KESTEAD XT TABLETS is not recommended in children.

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Heart

Caution

KESTEAD XT TABLETS is generally safe for heart patients, but they should be taken under medical supervision.

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Geriatrics

Caution

Geriatric patients may take KESTEAD XT TABLETS with caution, as age-related kidney or calcium metabolism changes require medical supervision. Always consult your doctor to ensure it's suitable for your health status and other medications.

Safety Information

Use this medication as recommended by the healthcare practitioner. Do not exceed the stated recommended daily dose. Keep your physician informed about your medical condition and medicines before taking the Kestead XT Tablet. Do not consume the Kestead XT Tablet if you are pregnant, planning to become pregnant, or are breastfeeding without a doctor's recommendation. Limit or avoid alcohol consumption. Quit smoking. Keep the Kestead XT Tablet away from sight and reach out to children. Store in a cool, dry way from direct sunlight.  

What if I have taken an overdose of KESTEAD XT TABLETS

If you take more than the prescribed amount, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, extreme thirst, or signs of high blood calcium levels.

Diet & Lifestyle Advise

  • Follow a strict low-protein or very low-protein diet under the close supervision of a clinical dietitian or your doctor to ensure the medication works as intended.
  • Ensure you consume enough daily calories from non-protein sources, such as healthy fats and carbohydrates, to prevent your body from breaking down its own muscle tissue for energy.
  • Keep all laboratory appointments to monitor your blood calcium, phosphate, and kidney function levels regularly.
  • Stay adequately hydrated, but strictly follow any fluid restriction guidelines provided by your kidney specialist.
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Have a query?

How Soon It Starts Working

The time required for KESTEAD XT TABLETS to start to work: The time required for KESTEAD XT TABLETS to show its action is not clinically established. 

The time for which the effects of KESTEAD XT TABLETS last: The duration of action for KESTEAD XT TABLETS is not clinically established.

Storage

•Store KESTEAD XT TABLETS at room temperature below 30°C, unless otherwise specified on the product label.

What if you forget to take KESTEAD XT TABLETS

Take the missed dose as soon as you remember, provided it is during or immediately after a meal. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Always inspect the blister packaging before use; do not take the medication if the foil is broken or damaged.
  • Ensure you have your blood calcium levels checked regularly, as this medicine can cause calcium buildup.
  • Do not take calcium supplements, antacids containing calcium, or vitamin D preparations without talking to your doctor first.
  • Always take this medicine during meals to maximise its nutritional effectiveness and prevent stomach upset.

verifiedApollotooltip
  • Antibiotics and Iron: May reduce the absorption of certain antibiotics (such as tetracyclines and quinolones) and iron supplements. Space these medications at least two hours apart from KESTEAD XT TABLETS .
  • Calcium and Vitamin D: Taking this medicine alongside calcium supplements or vitamin D analogues can significantly increase the risk of high blood calcium levels.

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verifiedApollotooltip
  • High-Calcium Foods: Consuming excessive amounts of dairy products or calcium-fortified foods may increase the risk of calcium buildup in the blood.

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FAQs

There are usually no symptoms of kidney disease in the early stages. Symptoms can include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in the urine at a more advanced stage.
Kestead XT Tablet may not be suitable for all kidney patients. Do not take this medication unless recommended by the doctor.
To treat your condition effectually, continue taking Kestead XT Tablet for as long as your doctor has prescribed. Please do not stop taking this medicine without consulting your doctor.
High blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, recurring kidney stones, an enlarged prostate, and long-term, frequent use of certain medicines, lithium, and nonsteroidal anti-inflammatory drugs (NSAIDs) are common causes of CKD.
CKD can be diagnosed using blood and urine tests such as glomerular filtration rate, serum creatinine levels and blood tests for urea nitrogen.
Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks. It should be used in pregnant women only if clinically needed, and benefits outweigh the risks.
KESTEAD XT TABLETS is used in the treatment of chronic kidney disease.
KESTEAD XT TABLETS mimics the same catabolic pathways as amino acids and works by improving the body's metabolism, thereby improving renal function.
CKD is usually caused by various conditions such as high blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, kidney stones that keep coming back, an enlarged prostate, and long-term or regular use of certain medicines such as lithium and non-steroidal anti-inflammatory drugs (NSAIDs).
CKD can be diagnosed using blood and urine tests. These tests look for high levels of certain substances in the blood and urine that show your kidneys are malfunctioning. The results of these tests can be used to determine the stage of your kidney disease.
There are usually no symptoms of kidney disease in the early stages. At a more advanced stage, symptoms can include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in your pee (urine). It may only be diagnosed if you have a blood or urine test for another reason and the results show a possible problem with your kidneys.
No, KESTEAD XT TABLETS is not same as arginine alpha-ketoglutarate. KESTEAD XT TABLETS contains alpha ketoanalogue which is a combination of different amino acids, whereas arginine alpha-ketoglutarate is a combination of alpha-ketoglutaric acid &essential amino acid arginine.
KESTEAD XT TABLETS should be swallowed as a whole with water; do not crush or chew it.
Side effects of KESTEAD XT TABLETS include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Talk to your doctor if you experience these side effects persistently.
This medicine works best when combined with a low-protein diet prescribed by your doctor. Taking it without dietary restrictions may reduce its benefits. Talk to your doctor or pharmacist about a customised diet plan.
Taking this medicine during meals helps your body absorb and use the nutrients properly to convert waste products into essential proteins. It also helps prevent stomach discomfort.
No, it cannot cure chronic kidney disease, but it helps delay the progression of the disease and reduces the accumulation of toxic waste in your blood. Talk to your doctor to understand how this fits into your overall treatment plan.
If blood tests show high calcium levels, your doctor may reduce your dose, recommend a lower-calcium diet, or temporarily stop the medication. Always follow your doctor's guidance.
There is limited safety data regarding its use during pregnancy. Talk to your doctor or pharmacist to weigh the potential benefits against any risks before starting this medicine.
Yes. The calcium salts present in this medicine can bind to iron in the gastrointestinal tract, reducing its absorption. To minimise this interaction, take iron supplements at least 2 hours before or after KESTEAD XT TABLETS or follow the schedule recommended by your doctor or pharmacist.
While there is no direct interaction, alcohol can put extra strain on your kidneys and affect your overall hydration status. It is best to consult your doctor about safe alcohol consumption.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Steadfast MediShield Pvt. Ltd, Plot # 330, Functional Industrial Estate, Patparganj, Delhi - 110 092
Other Info - KES0092

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