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compositionComposition:OSTIBIND-600MG
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Duofrax Tablet is a nutritional supplement which is used in bone remodelling and helps in healing fractured bone. This medicine contains ostibind, which helps repair shattered or fractured bones and efficiently decreases pain and inflammation. Some of the common side effects include nausea, acid reflux, diarrhoea, stomach pain, and constipation.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

OSTIBIND-600MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Duofrax Tablet

Duofrax Tablet is a suggested medication used to lower high phosphorus levels in the blood of patients with severe kidney disease. By binding to phosphorus in your diet, it helps prevent bone problems and cardiovascular issues caused by phosphorus buildup. There are several types of phosphate binders available. Although they all help lower phosphorus absorption from food, they contain different active ingredients and may have different precautions or side effects. Your healthcare provider will choose the one that is most appropriate for your individual needs.

Duofrax Tablet belongs to a group of medicines called phosphate binders. Different phosphate binders contain different active ingredients, but they all work by reducing the amount of phosphorus absorbed from food. Your doctor will prescribe the most appropriate phosphate binder based on your medical condition and blood test results.

To achieve the best results, you must take Duofrax Tablet consistently with every meal and snack as suggested by your doctor. Taking it with food is crucial because it binds to the phosphorus in your meals before your body can absorb it. Combining this treatment with a low-phosphorus diet recommended by a renal dietitian will significantly improve your health outcomes.

While taking Duofrax Tablet , some people may experience mild stomach upset, nausea, or constipation. However, contact your doctor immediately if you develop severe constipation, persistent stomach pain, vomiting, confusion, unusual tiredness, or any other symptoms that concern you. Your doctor may also monitor your blood mineral levels regularly to ensure the medicine is working safely and effectively.

Before starting this treatment, tell your doctor if you have a history of kidney stones, bowel disorders, or other significant medical conditions. Depending on the type of phosphate binder you are suggested, your doctor may recommend additional precautions or monitoring during treatment.

Duofrax Tablet can interact with other oral medications, including certain antibiotics and thyroid medicines, by reducing their absorption, so you must space them out. Avoid drinking alcohol and smoking, as they can worsen bone loss and kidney strain. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider to discuss the risks and benefits.

Uses of Duofrax Tablet

Your doctor may prescribe Duofrax Tablet to help manage the following conditions:

  • Hyperphosphatemia in chronic kidney disease: Duofrax Tablet helps lower elevated blood phosphorus levels for individuals undergoing dialysis or with advanced kidney disease.
  • Prevention of renal osteodystrophy: By keeping phosphorus and calcium levels balanced, Duofrax Tablet helps prevent the bone weakening and pain associated with kidney-related bone disease.
  • Cardiovascular protection in kidney disease: Reducing excess blood phosphorus helps prevent dangerous calcium-phosphate deposits from forming in your blood vessels and heart.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Protects Bone Health: By keeping phosphorus levels in check, Duofrax Tablet prevents your body from pulling calcium out of your bones, reducing the risk of painful bone disease and fractures.
  • Relieves Itching and Joint Pain: Managing your body's mineral levels also helps minimise chronic itching and joint pain, which are common and uncomfortable symptoms when phosphorus runs too high
  • Supports Heart and Blood Vessel Health: Additionally, controlling blood phosphorus helps protect your cardiovascular system. Keeping these mineral levels balanced prevents calcium buildup in your arteries, supporting long-term heart health and helping you maintain a more comfortable, active daily life.

Directions for Use

  • Duofrax Tablet can be taken with or without food.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow the Duofrax Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Duofrax Tablet Works

When your kidneys are not working fully, they cannot filter out excess phosphorus from your blood. Duofrax Tablet contains a phosphate-binding medicine that works inside your digestive tract rather than being absorbed into your bloodstream. When you take it with meals, it binds to the phosphorus present in food and forms a compound that cannot be absorbed by your body. This bound phosphorus is then passed out naturally in your stool, helping to lower the amount of phosphorus that enters your bloodstream.
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Alcohol

Caution

It is not known whether Duofrax Tablet interacts with alcohol or not. However, as a precautionary measure, it is advisable not to take or limit the consumption of alcohol.

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Pregnancy

Caution

Not enough scientific data is available on the use of Duofrax Tablet on pregnant women. Hence it is advised to consult your doctor if you are pregnant or planning pregnancy before taking Duofrax Tablet . Your doctor will weigh the benefits and potential risks before prescribing Duofrax Tablet .

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Breast Feeding

Caution

Not enough scientific data is available on the use of Duofrax Tablet on nursing mothers. Hence it is advised to consult your doctor if you are a breastfeeding mother. Your doctor will weigh the benefits and potential risks before prescribing Duofrax Tablet .

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Driving

Safe if suggested

It does not impact the ability to drive or operate machinery.

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Liver

Caution

Not enough scientific data is available on the use of Duofrax Tablet on liver impairment patients. Hence, you should inform your doctor before taking this medicine if you have liver problems.

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Kidney

Caution

Not enough scientific data is available on the use of Duofrax Tablet on kidney impairment patients. Hence, you should inform your doctor if you have kidney problems before taking this medicine.

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Children

Caution

Not enough scientific data is available for Duofrax Tablet . Hence, you should consult your doctor if you have any concerns regarding using Duofrax Tablet in children.

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Heart

Consult your doctor

Limited information is available on the use of Duofrax Tablet in heart patients. Therefore, please inform your doctor before taking this medicine if you have any heart problems.

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Geriatrics

Safe if suggested

Duofrax Tablet should be given to elderly patients only if suggested by a doctor. If you have any concerns about using Duofrax Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Duofrax Tablet

If you take more than the suggested dose of Duofrax Tablet , seek medical attention immediately, even if you do not have any symptoms. Take the medicine pack or suggested with you, if possible, to help healthcare professionals identify the treatment. In India, call 112 or go to the nearest emergency department if you or someone else has taken a suspected overdose or develops severe symptoms.

Diet & Lifestyle Advise

  • Limit high-phosphorus foods: Work with a renal dietitian to limit your intake of high-phosphorus foods like dairy products, nuts, seeds, colas, and processed foods with phosphate additives.
  • Read food labels carefully: Look for 'phos' in the ingredient list (such as dicalcium phosphate or sodium phosphate), as food additives are highly absorbable and can quickly raise your phosphorus levels.
  • Stay active safely: Engage in gentle weight-bearing exercises, like walking, to help maintain your bone density, but always consult your healthcare team before starting a new exercise routine.
  • Keep all laboratory appointments: Regular blood tests are essential to monitor your phosphorus, calcium, and kidney function so your doctor can adjust your treatment plan accurately. Your healthcare provider may also monitor other important markers, such as parathyroid hormone (PTH) and vitamin D levels, to assess your bone and mineral health and decide whether any changes to your treatment are needed. 
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Have a query?

How Soon It Starts Working

The time required for Duofrax Tablet to start to work: The time required for Duofrax Tablet to show its action is unknown. The time for which the effects of Duofrax Tablet last: The duration of action for Duofrax Tablet is unknown.

Storage

•Store Duofrax Tablet at controlled room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the container tightly closed to protect the medication from moisture and light.

What if you forget to take Duofrax Tablet

If you miss a dose and it is still during your meal or within 20 minutes of finishing your meal, take it immediately. If more time has passed, skip the missed dose and take your next dose with your next scheduled meal. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Take With Meals: Always take Duofrax Tablet during or immediately after meals to ensure it can bind to dietary phosphorus effectively.
  • Check Before Taking Supplements: Do not start any new vitamins, mineral supplements, antacids, or over-the-counter medicines without first checking with your doctor or pharmacist, as some products may interact with your phosphate binder or affect how well it works.
  • Watch for Constipation: Monitor your bowel movements; if you develop severe constipation, inform your doctor immediately, as this can lead to bowel complications.
  • Share Your Medication List: Keep a complete list of all medications, herbs, and supplements you take and share it with your healthcare team to avoid potential interaction issues.

verifiedApollotooltip
  • Certain antibiotics (like ciprofloxacin or doxycycline): Duofrax Tablet can bind to these medicines in your stomach, preventing your body from absorbing them. Take your antibiotics at least 2 hours before or 6 hours after taking Duofrax Tablet .
  • Thyroid medications (like levothyroxine): Taking Duofrax Tablet at the same time can reduce the effectiveness of your thyroid therapy. Space these medications several hours apart.
  • Iron supplements: Duofrax Tablet may lower the absorption of iron. Consult your pharmacist on how to schedule these supplements.

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verifiedApollotooltip
  • Follow the dietary advice provided by your healthcare team or renal dietitian. Depending on the type of phosphate binder you are taking, your doctor may recommend specific dietary adjustments to help control your phosphorus levels and support your overall treatment plan. 

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Habit Forming

No

Therapeutic Class

[NEUTRACEUTICAL]

FAQs

Duofrax Tablet belongs to the class of medications called nutritional supplements that primarily helps in bone remodelling and helps in healing fractured bone.
Duofrax Tablet contains Ostibind, a synergistic and bioactive combination of Cissus quadrangularis extract and Boswellia serrata extract (Aflapin). Cissus quadrangularis extract aids in remodelling and repairing shattered or fractured bones. Aflapin efficiently decreases pain and inflammation. As a result, Duofrax Tablet promotes fracture healing.
Before the inflammation is resolved, your symptoms may improve. Even if you feel better, it is recommended that you complete the entire course of treatment.
Duofrax Tablet is a nutraceutical supplement. It does not require a suggested to buy. Though it is an OTC medication, it should be used under the supervision of healthcare professionals.
Duofrax Tablet may be used as an adjuvant therapy to treat osteoporosis. But limited scientific evidence is available, so please check with your physician.
No, you should not take Duofrax Tablet without food. This medication works by binding to the phosphorus in your meals. If you take it on an empty stomach, it cannot perform its primary function. Taking it without food means it cannot bind effectively to the phosphorus in your meal, reducing its ability to control blood phosphorus levels. Talk to your doctor if you have questions about your meal schedule.
If you remember during your meal or within 20 minutes after finishing, take your missed dose. If more time has passed, skip the missed dose and take your next dose with your next meal. Do not take extra medicine to make up for a missed dose. Talk to your doctor or pharmacist if you frequently miss doses.
Before taking calcium supplements, antacids, or vitamin D products, speak with your doctor or pharmacist. Whether these products are appropriate depends on the specific phosphate binder you are taking and your blood calcium and phosphorus levels. Your healthcare provider will advise what is safe for you.
These tests help your healthcare provider monitor your phosphorus, calcium, and, when needed, parathyroid hormone (PTH) and vitamin D levels. Monitoring these markers helps ensure your treatment remains safe, effective, and tailored to your individual needs.
Yes, constipation is a common side effect of phosphate binders like Duofrax Tablet . Drinking adequate fluids (within your recommended daily fluid limit) and staying physically active can help. If your constipation becomes severe or painful, talk to your doctor right away.
The safety of Duofrax Tablet during pregnancy has not been fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you must discuss the potential risks and benefits with your healthcare provider. Talk to your doctor before starting or continuing this medication.
You should swallow Duofrax Tablet tablets whole with water. Crushing or chewing the tablets can alter how they release and work in your stomach, potentially reducing their effectiveness. If you have trouble swallowing tablets, talk to your doctor or pharmacist for alternative options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Sundyota Numandis , Pharmaceuticals Pvt. Ltd., 7th Floor, Safal Pegasus Tower-A, Prahladnagar, Ahmedabad - 380015, INDIA
Other Info - DUO0194
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