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CremaPeg Kit belongs to the class of medicines called stimulant laxatives used to cleanse the colon before a colonoscopy or barium enema. This combination medicines increases the intestine's water content and stimulates bowel movement, thereby, helps to cleanse the large intestine. Common side effects include diarrhoea, gastrointestinal pain/cramps, and abdominal discomfort.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

About CremaPeg Kit

CremaPeg Kit is an oral powder for solution used to treat temporary or long-term constipation, as well as severe bowel blockages known as fecal impaction (a severe build-up of hard stool that the body cannot pass on its own). It functions as an osmotic laxative, drawing water into your stool to make it softer and easier to pass. Your doctor may also prescribe it to clear your bowel before certain medical examinations or procedures.

For best results, you should take this medicine consistently at the same time each day as directed by your doctor. You can take this medicine with or without food. Increasing your daily intake of dietary fibre and drinking plenty of fluids can further support healthy digestion alongside this treatment. Most people notice relief from constipation within 1–3 days of starting treatment. When used to treat fecal impaction, higher doses are usually prescribed under medical supervision, and the time needed to completely clear the bowel may vary depending on the severity of the blockage.

While taking this medicine, you may experience mild side effects like stomach rumbling, mild bloating, or gas. However, if you experience severe diarrhoea, persistent abdominal pain, or signs of an allergic reaction, stop taking it and contact your doctor immediately.

Do not take this medicine if you have a bowel obstruction, a torn bowel wall (bowel perforation), toxic megacolon (a severe swelling of the large intestine), or active inflammatory bowel disease, including Crohn's disease or ulcerative colitis. Even if your symptoms are mild or moderate, tell your doctor before using this medicine so they can decide whether it is suitable for you. Before starting this medicine, tell your doctor if you have kidney problems, heart conditions, or are prone to dehydration.

This medicine can affect how well other medicines are absorbed because it makes food and medicines move faster through your gut. To reduce this effect, take other oral medicines at least two hours before or after taking CremaPeg Kit. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist before using this product to ensure it is safe for your specific needs.

Uses of CremaPeg Kit

Your doctor may recommend CremaPeg Kit to help:

  • Chronic and Occasional Constipation: It helps soften hard stools, making bowel movements regular, painless, and easier to pass.
  • Fecal Impaction: It helps clear a severe build-up of hard stool that the body cannot pass on its own, making bowel movements easier and relieving discomfort.
  • Bowel Cleansing: It clears the entire gastrointestinal tract before medical procedures, such as a colonoscopy, to ensure a clear view for the physician.

Key Benefits

When used as directed as part of your treatment plan, it may provide the following benefits:

  • Gentle Constipation Relief: It offers reliable, gentle relief from the physical discomfort of constipation without causing sudden, urgent cramping.
  • Softens Stools Naturally: By drawing water naturally into the colon, it softens hard, dry stools, allowing for comfortable and strain-free bowel movements.
  • Helps Maintain Hydration: Unlike some standard laxatives that can cause dehydration, this formulation contains essential minerals that help maintain your body's natural water and salt balance during treatment.
  • Supports Long-Term Digestive Care: This makes it a safer, more stable option for individuals who need ongoing digestive support.
Side effects of CremaPeg Kit
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing to achieve optimal results.
  • Read the label carefully and follow the directions for use. Mix CremaPeg Kit with the recommended amount of water and consume it as advised by the doctor.
  • Refrain from storing the mixture for later use.

How CremaPeg Kit Works

PEG 3350 is an osmotic agent, which means it attracts and holds water in your bowel like a sponge. This extra water softens hard stools, making them easier to pass and helping your bowels move more naturally. The added mineral salts—sodium chloride, sodium hydrogen carbonate, and potassium chloride—help replace minerals that may be lost during bowel cleansing. They help maintain your body's fluid balance and reduce the risk of dehydration while keeping sodium and potassium levels within a healthy range.
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Alcohol

Caution

It is not known if alcohol interacts with CremaPeg Kit. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

CremaPeg Kit should be used in pregnant women only if clinically needed, and benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking CremaPeg Kit if you are breastfeeding. Your doctor will decide if it can be taken by breastfeeding mothers or not.

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Driving

Caution

CremaPeg Kit is unlikely to affect your ability to drive. However, drive only if you are alert.

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Liver

Caution

If you have liver illness or impairment, talk to a doctor before taking CremaPeg Kit. Your doctor will only provide a prescription if the benefits outweigh the risks.

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Kidney

Caution

If you have kidney illness or impairment, talk to a doctor before taking CremaPeg Kit. Your doctor will only provide a prescription if the benefits outweigh the risks.

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Children

Caution

CremaPeg Kit should be given to children only if advised by the doctor.

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Heart

Caution

CremaPeg Kit should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using CremaPeg Kit.

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Geriatrics

Caution

CremaPeg Kit should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of CremaPeg Kit

If you take too much of this medicine, you may experience severe diarrhoea, vomiting, and abdominal pain, which can lead to severe dehydration. Seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay Hydrated: Drink plenty of fluids, especially water, throughout the day to help the laxative work effectively and to stay hydrated.
  • Eat More Fibre: Gradually increase your daily intake of dietary fibre by eating more whole grains, fruits, vegetables, and beans.
  • Stay Active: Engage in regular physical activity, such as a daily 30-minute walk, to naturally stimulate your bowel muscles.
  • Maintain a Regular Bathroom Routine: Do not ignore the urge to have a bowel movement; establish a regular, relaxed daily routine for using the bathroom.
health query

Have a query?

How Soon It Starts Working

The time required for CremaPeg Kit to start to work: The time required for CremaPeg Kit to show its action is unknown. The time for which the effects of CremaPeg Kit last: The duration of action for CremaPeg Kit is clinically unknown.

Storage

• Store the unmixed powder in its original packaging at room temperature, ideally between 15°C and 30°C (59°F to 86°F), away from direct moisture, heat, and light.

What if you forget to take CremaPeg Kit

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Inspect Before Use: Always inspect the powder before mixing; do not use it if the sachet is torn, damp, or clumped.
  • Mix Properly: Ensure the solution is fully dissolved and clear before drinking; do not consume it if the liquid remains cloudy or has floating particles.
  • Low-Salt Diet Alert: If you are on a restricted-sodium or low-potassium diet due to kidney or heart issues, consult your doctor, as this product contains mineral salts.
  • Use Only as Directed: Do not use this product for more than two weeks continuously unless specifically instructed by your physician.
  • Seek Medical Advice if Symptoms Persist: If your constipation does not improve after several days of treatment, or if it worsens, contact your doctor for a clinical evaluation.

Drug-Drug Interactions

verifiedApollotooltip
  • Narrow Therapeutic Index Medicines: This medicine may affect medicines where even a small change in the amount absorbed can cause problems, such as certain heart medicines, epilepsy medicines, or medicines used after organ transplantation. Tell your doctor about all the medicines you take so they can check for possible interactions.

Drug-Drug Interactions

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How does the drug interact with CremaPeg Kit:
Co- administration of CremaPeg Kit with Amitriptyline may cause stomach and upper intestinal discomfort.

How to manage the interaction:
Taking CremaPeg Kit with Biperiden is not recommended as it can lead to an interaction, but can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with CremaPeg Kit:
Taking CremaPeg Kit with Promethazine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit with Promethazine is not recommended, as it can lead to an interaction, they can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with CremaPeg Kit:
Taking CremaPeg Kit together with Propantheline can increase the chance of developing stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit with Propantheline is not recommended, as it can lead to an interaction, can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with CremaPeg Kit:
Taking CremaPeg Kit together with Phenindamine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit together with Phenindamine is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with CremaPeg Kit:
Taking CremaPeg Kit together with Mepenzolate can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit with Mepenzolate is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately.
How does the drug interact with CremaPeg Kit:
Co-administration of CremaPeg Kit with Dicyclomine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit with Dicyclomine is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with CremaPeg Kit:
Taking CremaPeg Kit with Dexchlorpheniramine can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit with Dexchlorpheniramine is not recommended as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, lightheadedness, vomiting, or dark stools, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with CremaPeg Kit:
Taking Difenoxin with Macrogol and Potassium chloride and Sodium bicarbonate and Sodium chloride together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Difenoxin with Macrogol and Potassium chloride and Sodium bicarbonate and Sodium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
How does the drug interact with CremaPeg Kit:
Co-administration of CremaPeg Kit with Dimenhydrinate can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Co-administration of CremaPeg Kit with Dimenhydrinate is not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. However, if you experience severe stomach pain, sudden dizziness, vomiting (especially with blood), or dark stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with CremaPeg Kit:
Taking Doxepin with CremaPeg Kit with doxepin can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking CremaPeg Kit with Doxepin is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with CremaPeg Kit when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[LAXATIVES]

FAQs

This medicine is designed to cleanse the bowel and usually causes frequent loose stools when used for bowel preparation before a colonoscopy, as this is the intended effect. It generally does not cause severe cramping or sudden urgency when used as directed. If you experience severe cramps, excessive diarrhoea, or signs of dehydration, contact your healthcare provider, as your dose may need adjustment or further evaluation.
This medicine is generally considered safe for pregnant or breastfeeding women because very little of the active ingredient is absorbed into the bloodstream. However, you should always consult your healthcare provider before starting any new medication during pregnancy. Talk to your doctor.
You should always mix the powder with plain, cold water to ensure the electrolyte and salt balance remains accurate. Once fully dissolved in water, you can add a small splash of orange juice or squash to improve the taste if needed.
While it is highly effective, it is generally intended for short-term relief of up to two weeks unless a doctor has diagnosed you with chronic constipation and prescribed long-term use. Overusing laxatives can affect your bowel's natural rhythm. If your symptoms worsen or do not improve, seek medical advice.
This formulation is typically sugar-free and gluten-free, making it suitable for individuals with diabetes or celiac disease. However, always check the exact packaging insert for specific ingredient variations. Read the medicine label carefully and follow the instructions provided.
If a child accidentally takes this medicine, monitor them for diarrhoea, stomach discomfort, or vomiting and encourage them to drink plenty of fluids. Seek medical advice immediately if they have taken a large amount, develop severe symptoms, or show signs of dehydration. Do not give additional doses unless instructed by a healthcare professional.
Because this medicine contains minerals such as sodium and potassium, people with kidney disease may have difficulty keeping these minerals at healthy levels. Your doctor may need to adjust your treatment or monitor you more closely to make sure the medicine is safe for you. Your doctor will need to evaluate if this is the right option for you. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - CRE0197
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