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Alphadol-C Capsule is used to treat low calcium and phosphate levels. It contains Alfacalcidiol and Calcium carbonate which work by strengthening the bones by increasing the calcium and phosphate levels in the blood. In some cases, this medicine may cause side effects such as stomach pain, constipation, stomach upset or gas. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Alphadol-C Capsule

Alphadol-C Capsule is a medicine used to treat or prevent low calcium levels and manage certain conditions that weaken the bones. It contains alfacalcidol, a vitamin D-related medicine, and calcium carbonate, a source of calcium. Together, they help the body maintain healthy calcium levels and support bone strength.

Alfacalcidol is converted by the liver into an active form of vitamin D, which helps the body absorb calcium from the gut. Calcium carbonate supplies the additional calcium needed for healthy bones, teeth, muscles, and nerves. Alphadol-C Capsule may be prescribed for conditions such as osteoporosis, hypocalcaemia (low calcium levels in the blood), hypoparathyroidism (a condition in which the parathyroid glands do not produce enough hormone to regulate calcium levels), or bone and mineral problems associated with chronic kidney disease. 

Take Alphadol-C Capsule exactly as prescribed by your doctor. Calcium carbonate is generally taken with food to improve absorption, but follow the instructions provided for your specific product. Swallow the medicine with water and do not take more than the recommended dose. Your doctor may arrange blood tests to monitor calcium, phosphate, kidney function, and other mineral levels during treatment. Do not take additional calcium or vitamin D supplements unless advised by your doctor.

Common side effects may include constipation, nausea, stomach discomfort, bloating, or wind. Taking too much calcium or alfacalcidol may cause high calcium levels in the blood. Contact your doctor if you develop persistent nausea or vomiting, loss of appetite, constipation, unusual thirst, frequent urination, muscle weakness, confusion, or severe tiredness. Seek immediate medical attention if you develop a serious allergic reaction, such as difficulty breathing or swelling of the face, lips, tongue, or throat.

Before taking Alphadol-C Capsule , tell your doctor if you have kidney problems, kidney stones, heart disease, high calcium or phosphate levels, or a condition that affects calcium or vitamin D levels. Do not take this medicine if you have high calcium levels in the blood unless specifically advised by your doctor. Also tell your doctor about all medicines and supplements you take, particularly water tablets (diuretics), digoxin, thyroid medicines, certain antibiotics, or other calcium- or vitamin D-containing products. If you are pregnant, planning a pregnancy, breastfeeding, an older adult, or considering this medicine for a child, consult your doctor before use.

Uses of Alphadol-C Capsule

Alphadol-C Capsule is used to manage low calcium levels and certain conditions that affect bone strength or mineral balance. Its main uses include: 

  • Osteoporosis: Alphadol-C Capsule helps prevent bone loss and reduces the risk of fractures by maintaining healthy calcium levels in the body.
  • Hypocalcaemia (Low blood calcium): It restores calcium levels to normal when the body cannot absorb or maintain enough on its own.
  • Renal osteodystrophy (bone problems caused by chronic kidney disease): Helps manage problems with how the body regulates calcium and maintains healthy bones when the kidneys are not working properly. Regular blood tests are needed to guide treatment safely.
  • Hypoparathyroidism (reduced activity of the parathyroid glands): Helps maintain calcium levels when the parathyroid glands do not produce enough parathyroid hormone, which normally helps regulate calcium in the body.
     

Key Benefits

Alphadol-C Capsule helps maintain healthy calcium levels and supports bone strength by combining alfacalcidol with calcium carbonate. Its main benefits include:

  • Supports strong bones: Calcium carbonate provides calcium needed to maintain bone structure, while alfacalcidol helps the body absorb and use calcium effectively.
  • Helps correct low calcium levels: Alphadol-C Capsule helps restore and maintain calcium levels when the body does not absorb enough calcium or has difficulty regulating it.
  • Supports bone health in chronic kidney disease: Alfacalcidol helps manage problems with how the body regulates calcium and maintains healthy bones when the kidneys are not working properly. Regular blood tests are needed to guide treatment safely.
  • Helps manage calcium imbalance in hypoparathyroidism: Alphadol-C Capsule supports calcium balance when the parathyroid glands do not produce enough hormone to regulate calcium levels.
     

Directions for Use

  • Alphadol-C Capsule can be taken with or without food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Alphadol-C Capsule as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Alphadol-C Capsule Works

Alphadol-C Capsule contains alfacalcidol and calcium carbonate, which work together to increase calcium availability and support healthy bones. Alfacalcidol is a vitamin D-related medicine. It is converted by the liver into an active form of vitamin D, which helps the body absorb more calcium from the gut and supports the normal balance of calcium and phosphate. Calcium carbonate provides calcium, an essential mineral needed to maintain healthy bones and teeth. Calcium also supports normal muscle function, nerve signalling, and other important body processes. Together, alfacalcidol and calcium carbonate help increase and maintain calcium levels in the body. This supports bone strength and helps manage conditions associated with low calcium levels or abnormal bone and mineral metabolism.
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Alcohol

Caution

The interaction of alcohol with Alphadol-C Capsule is unknown. Please consult a doctor before consuming alcohol with Alphadol-C Capsule .

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Alphadol-C Capsule is given to pregnant women if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Alphadol-C Capsule is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Alphadol-C Capsule may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Alphadol-C Capsule .

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Liver

Caution

Take Alphadol-C Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Alphadol-C Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Alphadol-C Capsule should be used in children only if recommended by a doctor.

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Heart

Caution

Alphadol-C Capsule should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using Alphadol-C Capsule .

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Geriatrics

Consult your doctor

Alphadol-C Capsule should be given to elderly patients only if prescribed by a doctor. Seek medical advice if you have any concerns.

What if I have taken an overdose of Alphadol-C Capsule

If you suspect an overdose, seek immediate medical attention. Taking too much of this medication can lead to dangerously high calcium levels in your blood, causing symptoms like severe nausea, confusion, muscle weakness, and kidney issues.

Diet & Lifestyle Advise

  • Eat calcium-rich foods: Include dairy products, leafy greens, broccoli, tofu, and calcium-fortified foods in your daily meals to complement your supplement.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidneys and lower the risk of developing kidney stones while taking calcium.
  • Limit caffeine and sodium: High amounts of salt and caffeine can increase the amount of calcium your body loses through urine, so use them in moderation.
  • Engage in weight-bearing exercise: Activities like walking, jogging, or light strength training help stimulate bone cells and build stronger bones alongside your medication.
  • Avoid smoking and limit alcohol: Both smoking and excessive alcohol intake interfere with how your body absorbs calcium and can accelerate bone loss.
     
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How Soon It Starts Working

The time required for Alphadol-C Capsule to start to work: Alphadol-C Capsule ideally shows its action within few hours after administration. The time for which the effects of Alphadol-C Capsule last: The duration of action for Alphadol-C Capsule is clinically unknown.

Storage

•Store Alphadol-C Capsule at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication in its original container to protect it from direct light and moisture, and do not store it in the bathroom where humidity is high.

What if you forget to take Alphadol-C Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Monitor your blood levels: Attend all scheduled doctor appointments and lab visits, as your doctor will need to run regular blood and urine tests to monitor your calcium and kidney function.
  • Watch for signs of high calcium: Be vigilant for symptoms of too much calcium in your body, such as an unusual metallic taste in the mouth, muscle pain, or extreme fatigue, and report them to your doctor.
  • Check other supplements: Carefully read the labels of any over-the-counter vitamins, antacids, or supplements you take to ensure you are not accidentally taking extra calcium or vitamin D.
  • Report kidney issues: Tell your healthcare provider immediately if you experience changes in your urination patterns or signs of kidney stones, like sharp pain in your back or side.
     

Drug-Drug Interactions

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  • Thiazide diuretics (water pills): Taking these with Alphadol-C Capsule can increase the risk of having too much calcium in your blood.
  • Certain antibiotics (like tetracyclines and fluoroquinolones): Alphadol-C Capsule can reduce the absorption of these medicines. Take your antibiotic at least 2 hours before or 4 to 6 hours after taking Alphadol-C Capsule .
  • Thyroid medications (like levothyroxine) and iron supplements: Calcium can prevent these drugs from being fully absorbed. Separate their intake by at least 4 hours.
  • Cardiac glycosides (like digoxin): High calcium levels can increase the risk of heart rhythm issues caused by these heart medicines.

Drug-Drug Interactions

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How does the drug interact with Alphadol-C Capsule:
Co-administration of Alfacalcidol and Calcium carbonate with Gefitinib may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Alfacalcidol and Calcium carbonate can be taken with Gefitinib if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Alphadol-C Capsule:
Co-administration of Dolutegravir with Alfacalcidol and Calcium carbonate can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although there is an interaction, Alfacalcidol and Calcium carbonate can be taken with dolutegravir if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Alphadol-C Capsule:
Co-administration of Alfacalcidol and Calcium carbonate with Ketoconazole may decrease the effectiveness of Ketoconazole.

How to manage the interaction:
Although there is an interaction, Alfacalcidol and Calcium carbonate can be taken with Ketoconazole if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Alphadol-C Capsule:
Co-administration of Alfacalcidol and Calcium carbonate with Raltegravir may interfere with the absorption and reduce the effectiveness of Raltegravir.

How to manage the interaction:
Taking Alfacalcidol and Calcium carbonate with Raltegravir may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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  • High-fibre foods and oxalic acid (such as spinach or rhubarb): These foods can bind to calcium and reduce its absorption in your intestines. Avoid eating large amounts of them at the same time you take Alphadol-C Capsule .
     
ALFACALCIDOL-0.25MCG+CALCIUM CARBONATE-200MGPotassium rich foods
Moderate

Drug-Food Interactions

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ALFACALCIDOL-0.25MCG+CALCIUM CARBONATE-200MGPotassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
Consumption of foods high in oxalic acid (spinach or rhubarb) with Alfacalcidol and Calcium carbonate may decrease calcium absorption. Avoid foods high in oxalic acid (spinach or rhubarb) while being treated with Alfacalcidol and Calcium carbonate.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Alphadol-C Capsule is used to treat low calcium and phosphate levels. It is also used to treat Vitamin D deficiency, renal osteodystrophy (changes in bone caused by kidney failure), hyperparathyroidism (parathyroid glands make high levels of calcium in the body), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), rickets or osteomalacia (softening or deformation of bones due to lack of calcium).
Alphadol-C Capsule contains Alfacalcidol and Calcium carbonate. Alfacalcidol is converted into the active form of vitamin D3 (calcitriol) and works by strengthening the bones by increasing the calcium and phosphate levels in the blood that are essential to forming healthy bones and teeth. It raises Vitamin D levels and thereby increases calcium levels in the blood. Calcium carbonate is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation.
Alphadol-C Capsule may be used to treat rickets or osteomalacia (softening and weakening of bones due to lack of calcium). Alphadol-C Capsule increases calcium levels in the body and helps in treating osteomalacia.
You are not recommended to take Alphadol-C Capsule with levothyroxine as co-administration of these two medicines at the same time may reduce the effectiveness of levothyroxine. However, if you are supposed to take both the medicines, you are advised to maintain a time gap of a minimum of 4 hours between taking Alphadol-C Capsule and levothyroxine.
Alphadol-C Capsule may cause kidney stones due to the accumulation of high levels of calcium when used for a prolonged time. Therefore, please consult a doctor before taking Alphadol-C Capsule if you have any kidney problems or a history of kidney stones.
You are recommended to avoid taking Alphadol-C Capsule if you have hypercalcaemia (high calcium levels in the blood) as it may worsen the condition. Therefore, please inform your doctor if you have hypercalcaemia before taking Alphadol-C Capsule .
Vitamin D can be found in various food sources, including mushrooms, particularly shiitake and portobello, and fortified plant-based milk like soy and almond milk. Fortified cereals and vegetarian vitamin D-fortified yoghurt are also good sources. Additionally, sun-dried mushrooms and orange juice fortified with vitamin D can contribute to your daily intake. Some brands of tofu and other soy products may also contain vitamin D. Naturally rich sources include cod liver oil and fatty fish like salmon, mackerel, and sardines. However, it's essential to check nutrition labels to confirm the presence of vitamin D in these foods.
Vitamin D is an essential nutrient that helps maintain overall health. It keeps bones and teeth healthy by helping the body absorb calcium and phosphorus. It also supports the immune system, helps to regulate mood, and contributes to heart health.
The common side effects of Alphadol-C Capsule are stomach pain, itching, rash, constipation, stomach upset, or gas. Most of these side effects of Alphadol-C Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is highly recommended to take Alphadol-C Capsule with or immediately after a meal. Food helps your body absorb the calcium more effectively and reduces the likelihood of experiencing an upset stomach. Talk to your doctor or pharmacist if you have questions about your specific dosing schedule.
Constipation is a common side effect of calcium-based supplements. You can manage this by drinking plenty of water, eating high-fibre foods, and staying physically active. If the constipation is severe or persistent, talk to your doctor or pharmacist before taking laxatives.
If you have a history of kidney stones, you must use Alphadol-C Capsule with caution. Your doctor will need to monitor your calcium levels and kidney function closely. Talk to your doctor before starting this supplement to ensure it is safe for you.
Pregnant women have specific calcium and vitamin D requirements, but taking too much can be harmful to the developing baby. You should only use Alphadol-C Capsule during pregnancy if it is specifically prescribed by your healthcare provider. Talk to your doctor to determine the safest approach.
Signs of high calcium (hypercalcaemia) include extreme thirst, frequent urination, nausea, loss of appetite, muscle weakness, and confusion. If you experience these symptoms, contact your healthcare provider immediately.
Alphadol-C Capsule already contains an active form of Vitamin D (alfacalcidol). Taking additional Vitamin D supplements without medical supervision can lead to a dangerous buildup of calcium in your body. Talk to your doctor before combining any supplements.
It is best to limit your alcohol consumption while taking Alphadol-C Capsule . Alcohol can interfere with your body's ability to absorb calcium and can also weaken your bones over time. Talk to your doctor or pharmacist for personalised advice.

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Country of origin

INDIA

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru – 140501, Punjab
Other Info - ALP0005
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