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  3. Alphadol-0.25 Capsule 10's

Alphadol-0.25 Capsule 10's, Pack of 10 CapsuleS
Alphadol-0.25 Capsule 10's, Pack of 10 CapsuleS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Alphadol-0.25 Capsule is used to treat low blood calcium and phosphate levels. It effectively treats Vitamin D deficiency, renal osteodystrophy (changes in bone caused by kidney failure), hyperparathyroidism (parathyroid glands make high levels of calcium in the body), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), hypocalcaemia (low levels of calcium), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). It contains Alfacalcidol, which is converted into the active form of vitamin D3 (calcitriol) and works by strengthening the bones by increasing the calcium and phosphate levels in the blood. In some cases, it may cause side effects such as weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, a metallic taste, nausea, and vomiting.

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Composition :

ALFACALCIDOL-0.25MCG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Alphadol-0.25 Capsule

Alphadol-0.25 Capsule is primarily used to treat low blood calcium and phosphate levels. Alphadol-0.25 Capsule effectively treats Vitamin D deficiency, renal osteodystrophy (changes in bone caused by kidney failure), hyperparathyroidism (parathyroid glands make high levels of calcium in the body), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), hypocalcaemia (low levels of calcium), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). Vitamin D deficiency occurs when your body has low Vitamin D levels and is caused by inadequate nutrition, intestinal malabsorption, or lack of exposure to sunlight.

Alphadol-0.25 Capsule contains 'Alfacalcidol,' which is an analogue of Vitamin D. It is a nutritional supplement activated by liver enzymes after intake. Alfacalcidol is further converted into the active form of vitamin D3 (calcitriol) and works by strengthening the bones by increasing the calcium and phosphate levels in the blood. Calcium and phosphate are essential substances for forming healthy bones and teeth.

Your doctor will decide the dosage based on your medical condition. In some cases, it may cause side effects such as weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, a metallic taste, nausea, and vomiting. Most of these side effects of Alphadol-0.25 Capsule do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Please tell your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrients from food). Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, sarcoidosis (growth of inflammatory cells in different parts of the body), or kidney stones. Pregnant or breastfeeding women should consult their doctor before taking Alphadol-0.25 Capsule . Alphadol-0.25 Capsule is safe to use in children when advised by the doctor.

Uses of Alphadol-0.25 Capsule

Alphadol-0.25 Capsule is used in the treatment of low blood calcium and phosphate levels. It is effective in managing the following conditions:<br/>Vitamin D Deficiency: Alphadol-0.25 Capsule helps replenish vitamin D levels by converting to calcitriol (Vitamin D3) and enhancing calcium absorption.<br/>Hypocalcaemia: Alphadol-0.25 Capsule helps raise blood calcium levels by stimulating calcium absorption from the intestine and reabsorption from the bones and kidneys.<br/>Osteomalacia (in adults) or Rickets (in children): Alphadol-0.25 Capsule helps strengthen bones by improving calcium and phosphate absorption and promoting bone mineralisation (deposition of minerals in bone tissue).<br/>Hyperparathyroidism: Alphadol-0.25 Capsule helps suppress excess parathyroid hormone (PTH) levels, which can cause bones to weaken.<br/>Hypoparathyroidism: Alphadol-0.25 Capsule compensates for low PTH levels by maintaining calcium and phosphate balance in the body.<br/>Renal Osteodystrophy: Alphadol-0.25 Capsule helps manage this condition by regulating calcium, phosphate, and parathyroid hormone (PTH) levels, thereby improving bone quality and reducing fractures and pain.<br/>

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Directions for Use

  • Alphadol-0.25 Capsule should be taken with food for better absorption.
  • Your doctor will recommend the appropriate dose and duration of this medication based on your medical condition.
  • Swallow Alphadol-0.25 Capsule as a whole with a glass of water
  • Do not crush, chew, break, or open it.

Medicinal Benefits

Alphadol-0.25 Capsule is used to treat low blood calcium and phosphate levels. It contains Alfacalcidol, a vitamin D analogue. It is used to treat vitamin D deficiency, renal osteodystrophy, hyperparathyroidism, hypoparathyroidism, hypocalcaemia, and rickets or osteomalacia. Liver enzymes activate Alphadol-0.25 Capsule after intake, which is further converted into the active form of vitamin D3 (calcitriol). It works by strengthening the bones by increasing the calcium and phosphate levels in the blood.

How Alphadol-0.25 Capsule Works

Alphadol-0.25 Capsule contains 'Alfacalcidol,' which is an analogue of Vitamin D. It is a nutritional supplement activated by liver enzymes after intake. Alfacalcidol is further converted into the active form of vitamin D3 (calcitriol) and works by strengthening the bones by increasing the calcium and phosphate levels in the blood. Calcium and phosphate are essential substances for forming healthy bones and teeth.

Storage

Keep out of sight and reach of children.
Side effects of Alphadol-0.25 Capsule
  • High levels of phosphate in the blood need immediate medical attention.
  • Get a physical examination and blood tests to identify factors causing high phosphate levels to manage the outcomes.
  • Avoid consuming phosphate rich foods like egg yolks, soft drinks, milk, chocolate etc.
  • Talk to your dietician and consume foods which can maintain ideal phosphorus levels.
  • Maintain a healthy weight and implement good habits to prevent stress and anxiety.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Reduce sodium intake to minimize calcium excretion in urine.
  • Limit animal protein consumption to decrease urinary calcium levels.
  • Increase fluid intake by drinking plenty of water to dilute urine.
  • Moderate calcium intake based on individual needs, avoiding drastic restriction.
  • Limit oxalate-rich foods like spinach and chocolate to minimize kidney stone formation.
  • Stay hydrated by drinking plenty of water.
  • Consider reducing vitamin D supplementation if excessive intake is contributing to hypercalciuria.
  • Regularly monitor urine calcium levels through 24-hour urine tests.
  • Always seek guidance from a healthcare expert prior to implementing substantial changes to your diet or lifestyle routine.

What if I have taken an overdose of Alphadol-0.25 Capsule

Please do not take more than the prescribed dose of Alphadol-0.25 Capsule as it may cause overdose, resulting in too much calcium or phosphate in the blood. If you suspect you have taken an overdose or notice signs, please consult a doctor immediately.

Drug Warnings

Let your doctor know if you are allergic to Alphadol-0.25 Capsule or its inactive components. Alphadol-0.25 Capsule is not recommended if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, sarcoidosis (growth of inflammatory cells in different parts of the body), and kidney stones. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Alphadol-0.25 Capsule is excreted into the breast milk; hence, consult your doctor before taking Alphadol-0.25 Capsule if you are a breastfeeding mother. Drinking alcohol can affect calcium absorption; therefore, it is advised to limit alcohol intake while using Alphadol-0.25 Capsule . Alphadol-0.25 Capsule is safe to use in children only when advised by the doctor.

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.
  • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D-fortified milk.
  • Snack on calcium-rich nuts like Brazil nuts or almonds. 
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for an added source of calcium in your diet.

Habit Forming

No

Therapeutic Class

VITAMIN D ANALOGS

Alphadol-0.25 Capsule Substitute

Substitutes safety advice
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, it is advised to limit alcohol intake while using Alphadol-0.25 Capsule .

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Pregnancy

Caution

During pregnancy, use higher doses of Alphadol-0.25 Capsule than the daily dietary allowance only when advised by the doctor. Your doctor will weigh the potential risks and benefits before recommending Alphadol-0.25 Capsule .

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Breast Feeding

Caution

Consult your doctor before taking Alphadol-0.25 Capsule if you are breastfeeding. Alphadol-0.25 Capsule can be passed into breast milk. If Alphadol-0.25 Capsule is used during breastfeeding, please monitor the serum calcium levels of the mother and the infant.

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Driving

Caution

If you experience any dizziness while using Alphadol-0.25 Capsule , do not drive or operate machinery. Please consult your doctor if you experience any dizziness.

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Liver

Caution

Let your doctor know if you have any history of liver disease before taking Alphadol-0.25 Capsule . Hepatic impairment or liver disease can alter the metabolic and therapeutic activity of certain forms of Vitamin D.

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Kidney

Caution

It is advised to seek a doctor's advice before starting Alphadol-0.25 Capsule if you have kidney diseases like kidney stones or are undergoing dialysis.

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Children

Consult your doctor

The doctor will decide the dosage of Alphadol-0.25 Capsule based on the child's age and weight.

FAQs

Alphadol-0.25 Capsule is used to treat low blood calcium and phosphate levels. It effectively treats Vitamin D deficiency, renal osteodystrophy (changes in bone caused by kidney failure), hyperparathyroidism (parathyroid glands make high levels of calcium in the body), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), hypocalcaemia (low levels of calcium), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium).

Alphadol-0.25 Capsule is a dietary supplement that treats low levels of calcium and phosphate in the blood. It consists of Alfacalcidol, an analogue of Vitamin D. When you do not get enough Vitamin D from food sources and sunlight exposure, Alphadol-0.25 Capsule helps balance those low levels.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Milk is considered to be the best source of calcium. You can take Alphadol-0.25 Capsule with milk.

Alphadol-0.25 Capsule can cause kidney stones due to excessive calcium deposition when used for an extended period. Please consult your doctor before taking Alphadol-0.25 Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.

Alphadol-0.25 Capsule is used to increase low levels of calcium in the body. Hence, it is not advised to use Alphadol-0.25 Capsule during hypercalcaemia, since it causes the overdose of calcium, leading to kidney stones and other effects.

Alphadol-0.25 Capsule should be used with caution if you have hypercalcaemia (high calcium levels), hypervitaminosis D (high vitamin D levels), malabsorption syndrome (difficulty absorbing nutrition from food), heart/kidney/liver/blood vessel diseases, diabetes, phenylketonuria, and kidney stones. Please consult your doctor before starting Alphadol-0.25 Capsule if you have any history of these diseases.

Alphadol-0.25 Capsule may increase the absorption of Aluminium in antacids. Hence, it is advised to take Alphadol-0.25 Capsule two hours before, or four hours after taking antacids.

Country of origin

INDIA

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru – 140501, Punjab
Other Info - ALP0004

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:44 AM IST

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Reference

  1. https://www.drugs.com/uk/pdf/leaflet/1067204.pdf
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Alfacalcidol#section=Pharmacology-and-Biochemistry
  3. https://www.medicines.org.uk/emc/files/pil.5516.pdf
  4. https://www.webmd.com/drugs/2/drug-10175/vitamin-d3-oral/details

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