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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zuriclop AV 40 Capsule is used for the prevention of heart attack and stroke. It also lowers the raised level of bad cholesterol (especially those who are at high risk of heart disease). It contains Atorvastatin and Aspirin, which blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG). It increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Aspirin is a blood thinner or anti-platelet (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Thus, this medicine help to reduce the risk of heart attack, stroke, and heart-related chest pain (angina). Additionally, it is also given to the patients who had a recent heart bypass surgery (CABG) to control the level of cholesterol and prevent blood clots. In some cases, you may experience side effects such as headache, ankle swelling (oedema), dark urine, muscle weakness, slow heart rate, dizziness, and nausea.

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Manufacturer/Marketer :

Zurinova Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zuriclop AV 40 Capsule

Zuriclop AV 40 Capsule is used for the prevention of heart attack and stroke. A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of the arteries. The blockage is most often a buildup of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Zuriclop AV 40 Capsule is composed of rosuvastatin and aspirin. This medicine reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG). It also collectively prevents the formation of clots in the blood vessels. Together, Zuriclop AV 40 Capsule helps to reduce the risk of heart attack, stroke, and heart-related chest pain (angina).

In some cases, you may experience headache, ankle swelling (oedema), dark urine, muscle weakness, slow heart rate, dizziness, and nausea. Most of these side effects of Zuriclop AV 40 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Take Zuriclop AV 40 Capsule with or without food. Your doctor will advise you on how often you take your medicine based on your medical condition. Try not to stop taking this medicine on your own. Do not chew, break, or crush the medicine.

Avoid taking Zuriclop AV 40 Capsule if you are allergic to it. Stopping Zuriclop AV 40 Capsule abruptly may worsen your condition and increase your risk of future heart attack. Let your doctor know if you have any active liver disease, bleeding issues, muscle problems, are pregnant or planning to become pregnant or are breastfeeding. Patients should inform the doctor that they are taking Zuriclop AV 40 Capsule before any surgery is scheduled or any new medicine is taken.

Uses of Zuriclop AV 40 Capsule

Zuriclop AV 40 Capsule is used in prevention of heart attack and stroke. The detailed uses of Zuriclop AV 40 Capsule are as follows: 

  • Cardiovascular Protection: Zuriclop AV 40 Capsule is frequently prescribed to prevent blood clots in individuals at high risk of heart attacks or strokes. 
  • Anti-inflammatory Effects: Zuriclop AV 40 Capsule is known for its ability to reduce inflammation associated with various medical conditions.
  • Management of Angina: Zuriclop AV 40 Capsule supports the management of angina symptoms by enhancing blood flow and reducing the heart's workload.
  • Post-surgical Care: Zuriclop AV 40 Capsule is administered after certain surgeries to lower the risk of thromboembolic events, promoting smoother recovery.

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Directions for Use

  • Zuriclop AV 40 Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Zuriclop AV 40 Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Zuriclop AV 40 Capsule is composed of two medicines: Atorvastatin and Aspirin.
  • Atorvastatin is an antilipemic agent (cholesterol-lowering) which works by blocking liver enzymes, causing the liver to make less cholesterol.
  • It also lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood.
  • Aspirin is an anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together.
  • Zuriclop AV 40 Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.
  • Zuriclop AV 40 Capsule reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). 

How Zuriclop AV 40 Capsule Works

Zuriclop AV 40 Capsule is composed of two medicines namely: Atorvastatin and Aspirin. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG). It increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Aspirin is a blood thinner or anti-platelet (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Together Zuriclop AV 40 Capsule help to reduce the risk of heart attack, stroke, and heart-related chest pain (angina). Additionally, it is also given to the patients who had a recent heart bypass surgery (CABG) to control the level of cholesterol and prevent blood clots.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Zuriclop AV 40 Capsule
  • Break down of muscles tissue leads to muscle weakness and it can be managed by eating often.
  • Observe your movements and understand why the muscle is weakening and breaking down.
  • Regularly do strengthening exercises to improve blood flow throughout the body and reduce weakness.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet, quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.
  • Physical therapy (includes strength and range of motion exercises) and occupational therapy (focuses on helping you live your everyday life with more comfort) may help in the treatment of myopathy.
  • Consult your doctor for medications to reduce inflammation, improve muscle function or treat underlying infections or conditions.

What if I have taken an overdose of Zuriclop AV 40 Capsule

Do not take more than the prescribed dose of Zuriclop AV 40 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Let your doctor know if you are highly sensitive to atorvastatin or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant, or are breastfeeding.
  • The patient should inform the doctor that they are taking Zuriclop AV 40 Capsule before any surgery is scheduled or any new medicine is taken.
  • Atorvastatin present in Zuriclop AV 40 Capsule is a pregnancy category X drug so it is contraindicated in pregnant women.
  • Zuriclop AV 40 Capsule contains atorvastatin, which can cause muscle problems like myopathy and rhabdomyolysis. So, any signs of muscle pain, tenderness, or weakness during the initial months of the treatment should be closely monitored.
  • Safety and effectiveness of Zuriclop AV 40 Capsule have not been established, so its use should be avoided in paediatric patients or children less than 12 years of age.
  • Abrupt discontinuation of Zuriclop AV 40 Capsule may lead to the occurrence of cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Zuriclop AV 40 Capsule .
  • Do not drive or operate machinery if you experience dizziness or drowsiness while using Zuriclop AV 40 Capsule .
  • Please do not consume alcohol since it may worsen the side effects like dizziness and increased blood pressure. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zuriclop AV 40 Capsule:
Combining Ketorolac tromethamine with Zuriclop AV 40 Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Zuriclop AV 40 Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Zuriclop AV 40 Capsule:
Co-administration of Ketorolac and Zuriclop AV 40 Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Zuriclop AV 40 Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zuriclop AV 40 Capsule:
Taking Zuriclop AV 40 Capsule with Posaconazole can increase the blood levels of Zuriclop AV 40 Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Zuriclop AV 40 Capsule, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AspirinDrotrecogin alfa (activated)
Severe
How does the drug interact with Zuriclop AV 40 Capsule:
Coadministration of Zuriclop AV 40 Capsule and Drotrecogin alfa may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Drotrecogin alfa (activated) and Zuriclop AV 40 Capsule, but it can be taken if prescribed by a doctor. It's important to keep a close eye on any signs of bleeding and let a doctor know right away if you experience any of these symptoms - close monitoring or bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zuriclop AV 40 Capsule:
Using Zuriclop AV 40 Capsule together with tirofiban can cause you to bleed more easily.

How to manage the interaction:
Co-administration of Zuriclop AV 40 Capsule with Tirofiban can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, bruising, throwing up, headache, feeling dizzy, weakness, or seeing blood in your urine or stools. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zuriclop AV 40 Capsule:
Coadministration of Zuriclop AV 40 Capsule with Acetazolamide may cause side effects.

How to manage the interaction:
Although there is a possible interaction between Zuriclop AV 40 Capsule and acetazolamide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, and seizure, please contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zuriclop AV 40 Capsule:
Using Deferasirox together with Zuriclop AV 40 Capsule may increase your risk of developing gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Zuriclop AV 40 Capsule with Deferasirox together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, breathing difficulty, muscle pains, tiredness, weakness, confusion, and abnormal heart rhythm, consult the doctor. If you experience diarrhea or vomiting while taking these medications, stay hydrated. Do not stop taking any medications without talking to a doctor.
AspirinDefibrotide
Severe
How does the drug interact with Zuriclop AV 40 Capsule:
Coadministration of Zuriclop AV 40 Capsule with Defibrotide may increase the risk of bleeding.

How to manage the interaction:
Taking Zuriclop AV 40 Capsule with Defibrotide together can result in an interaction, but it can be taken if a doctor has advised it. It is important to closely monitor your body for any signs of bleeding issues. If you notice any symptoms like bleeding, bruising, dizziness, severe headache, weakness, or vomiting, it is recommended to contact a doctor right away. Regular check-ups and tests will help ensure your safety and well-being. Do not discontinue any medications without consulting a doctor.
AspirinDicoumarol
Severe
How does the drug interact with Zuriclop AV 40 Capsule:
Using warfarin together with Dicoumarol may cause you to bleed more easily.

How to manage the interaction:
Taking Zuriclop AV 40 Capsule with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any bleeding, it's important to contact a doctor right away. They will be able to help you and provide the necessary care. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zuriclop AV 40 Capsule:
Coadministration of Zuriclop AV 40 Capsule and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Zuriclop AV 40 Capsule and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet, especially rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants, which help to lower LDL - low density lipoprotein (bad cholesterol)
  • Minimize the intake of added sugar. The American Heart Association (ADA) recommends that one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

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Alcohol

Unsafe

Zuriclop AV 40 Capsule should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol. Drinking alcohol with Zuriclop AV 40 Capsule may potentiate gastric or stomach bleeding and ulcer symptoms. So, try to avoid or limit consumption of alcoholic beverages while using Zuriclop AV 40 Capsule .

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Pregnancy

Unsafe

Zuriclop AV 40 Capsule contains Atorvastatin which is a pregnancy category X medicine. So, it is not recommended for the pregnant mother, or those who are planning to get pregnant. In an extreme case, your doctor will decide whether Zuriclop AV 40 Capsule can be given or not.

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Breast Feeding

Consult your doctor

Take Zuriclop AV 40 Capsule only when prescribed, as it is known to pass on in a limited quantity via breast milk to the child. Contact your doctor before using Zuriclop AV 40 Capsule .

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Driving

Caution

Drive with caution as, Zuriclop AV 40 Capsule can cause blurry vision and may affect your driving ability.

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Liver

Caution

Zuriclop AV 40 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. Dose can be adjusted by your doctor.

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Kidney

Caution

Zuriclop AV 40 Capsule to be taken with caution, especially if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Unsafe

Zuriclop AV 40 Capsule is not recommended for children below the age of 16 years. The safety and effectivenss of Zuriclop AV 40 Capsule has not been established in children due to limited testing of this drug on children by competent authorities across the world.

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Heart

Zuriclop AV 40 Capsule is often prescribed to patients with heart problems to manage high cholesterol and reduce cardiovascular risk. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Safe if prescribed

Zuriclop AV 40 Capsule is generally safe for use in elderly patients if recommended by the physician.

FAQs

Zuriclop AV 40 Capsule is used for the prevention of heart attack and stroke. It lowers bad cholesterol levels and increases good cholesterol levels.

Yes, the use of Zuriclop AV 40 Capsule can cause dizziness in some patients. They may experience symptoms such as feeling of fainting, weakness, or lightheadedness. In case you experience such symptoms, it is better to rest for some time until you feel better.

Usually Zuriclop AV 40 Capsule is prescribed for a long-term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

Yes, Zuriclop AV 40 Capsule is known to cause upset stomach. So, it should be taken with food so as to avoid discomfort. If even then, problem persists, please consult your doctor for best advise. In rare cases gastro intestinal bleeding can be observed due to blood thinning action of aspirin present in Zuriclop AV 40 Capsule .

Theres no strong evidence to suggest that taking Zuriclop AV 40 Capsule will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if youre likely to get pregnant or pregnant.

Country of origin

India

Manufacturer/Marketer address

Flat F2, First Floor, Shri Jayamm, New No. 37, Old No. 18, Brindavan Street, West Mambalam, Chennai-600033
Other Info - ZUR0030

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