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compositionComposition:VILAZODONE HYDROCHLORIDE-40MG
prescription
Prescription Medicine
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ZOVANE 40MG TABLET is used to treat major depressive disorder. It contains Vilazodone hydrochloride which increases levels of a chemical messenger (serotonin) in the brain that helps to improve mood, feelings of well-being, and happiness. In some cases, this medicine may cause side effects such as diarrhoea, nausea, vomiting, and insomnia. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

VILAZODONE HYDROCHLORIDE-40MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ZOVANE 40MG TABLET

ZOVANE 40MG TABLET is a prescription oral medication primarily used to treat major depressive disorder in adults. It belongs to a class of medications known as antidepressants, which work to restore chemical balance in the brain. Its main medical purpose is to help relieve the persistent feelings of sadness, anxiety, and loss of interest associated with depression.

To get the best results, you must take ZOVANE 40MG TABLET consistently every single day, ideally at the same time. It is highly important to always take this medication with food, as eating a meal helps your body absorb the medicine properly. Making simple lifestyle adjustments, such as keeping a regular sleep schedule and engaging in light physical activity, can also support your treatment.

While taking ZOVANE 40MG TABLET, you may experience mild side effects like nausea, diarrhoea, or trouble sleeping. However, you must contact your doctor immediately if you experience severe symptoms like unusual bleeding, severe dizziness, or sudden changes in your mood or behaviour. Your safety is key, and monitoring how you feel is an important part of your recovery.

Before starting ZOVANE 40MG TABLET, talk to your doctor if you have a history of seizures, bleeding disorders, or bipolar disorder. Do not take this if you are currently taking a monoamine oxidase inhibitor (MAOI) or have stopped taking one within the last 14 days, as this can cause a life-threatening reaction.

This medicine can interact with alcohol, which can worsen drowsiness, so it is best to avoid drinking while on this treatment. You should also tell your doctor if you take other prescription drugs, over-the-counter pain relievers, or herbal supplements. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, consult your healthcare provider to discuss the safety of this medication for your specific situation.

Uses of ZOVANE 40MG TABLET

ZOVANE 40MG TABLET is used in the treatment of major depressive disorder. The detailed use of ZOVANE 40MG TABLET is as follows:

  • Major Depressive Disorder (MDD): ZOVANE 40MG TABLET helps balance chemical messengers in the brain to relieve persistent sadness, loss of interest in daily activities, and other emotional symptoms of depression.

Key Benefits

ZOVANE 40MG TABLET helps manage symptoms of depression, improving mood and supporting emotional well-being.

The following are the benefits of ZOVANE 40MG TABLET:

  • Helps improve mood and reduce symptoms of depression.
  • Reduces feelings of sadness, hopelessness, and emptiness.
  • Improves energy levels and motivation for daily activities.
  • Supports healthier sleep patterns and emotional well-being.
  • Promotes better focus and participation in work or social activities.
  • Improves overall quality of life with consistent use of this medicine.
Side effects of Zovane 40mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.

Directions for Use

  • ZOVANE 40MG TABLET should be taken with food. Taking it on an empty stomach may lead to insufficient drug levels and reduce its effectiveness.
  • It is recommended to take ZOVANE 40MG TABLET once daily or as advised by your doctor.
  • Swallow ZOVANE 40MG TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

How ZOVANE 40MG TABLET Works

ZOVANE 40MG TABLET works by targeting serotonin, a natural chemical messenger in the brain that plays a key role in regulating mood, sleep, and emotional stability. It helps the brain in two distinct ways. First, it blocks the reabsorption of serotonin, which keeps more of this chemical active and available in the brain. Second, it acts directly on specific serotonin receptors to help them work more efficiently. This dual action helps restore chemical balance, leading to improved mood and a reduction in depressive symptoms.
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Alcohol

Caution

Avoid consumption of alcohol as it may interact with ZOVANE 40MG TABLET and increase the risk of side-effects.

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Pregnancy

Caution

ZOVANE 40MG TABLET should be used in pregnant women only when clinically needed and if benefits outweigh the risks.

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Breast Feeding

Caution

ZOVANE 40MG TABLET should be used in breastfeeding mothers when clinically needed and if benefits outweigh the risks.

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Driving

Caution

Do not drive or operate heavy machinery as ZOVANE 40MG TABLET may affect alertness.

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Liver

Caution

ZOVANE 40MG TABLET should be used with caution in patients with severe liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

ZOVANE 40MG TABLET should be used with caution in patients with severe kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

ZOVANE 40MG TABLET is not recommended for children and adolescents below 18 years as it can cause suicidal tendencies.

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Heart

Safe if prescribed

ZOVANE 40MG TABLET can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

ZOVANE 40MG TABLET can be given in elderly patients with extreme caution, due to the cause of adverse effects like liver/kidney problems.

What if I have taken an overdose of ZOVANE 40MG TABLET

If you suspect an overdose, seek immediate medical attention or call your local poison control centre. Symptoms of an overdose can include severe dizziness, nausea, vomiting, or a rapid heart rate.

Diet & Lifestyle Advise

  • Take with food: Always take this medicine with a meal, as taking it on an empty stomach can reduce the amount your body absorbs.
  • Maintain a sleep routine: Follow a regular sleep schedule to help manage insomnia, which may occur with depression or as a side effect of this medicine.
  • Stay physically active: Include light exercise, such as walking, in your daily routine to help improve your mood and support your overall well-being.
  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it can worsen depression symptoms and increase drowsiness.
health query

Have a query?

How Soon It Starts Working

The time required for ZOVANE 40MG TABLET to start to work: ZOVANE 40MG TABLET ideally shows its action within 4 to 5 hours after administration The time for which the effects of ZOVANE 40MG TABLET last: The time for which the effects of ZOVANE 40MG TABLET last: 20 to 25 hours

What if you forget to take ZOVANE 40MG TABLET

If you miss a dose, take it with food as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at once to make up for a missed one.

Storage

•Store ZOVANE 40MG TABLET at room temperature, between 68°F and 77°F (20°C and 25°C). .

Drug Warnings

  • Watch for mood changes: This medicine may increase the risk of suicidal thoughts or unusual behaviour in children, teenagers, and young adults under 25 years, especially when starting treatment or after a dose change. Family members and caregivers should watch for mood or behaviour changes and contact the doctor immediately if they notice anything concerning.
  • Do not stop suddenly: Do not stop taking this medicine without your doctor's advice. Stopping it suddenly can cause withdrawal symptoms such as dizziness, headache, or irritability, so your doctor will reduce the dose gradually.
  • Be careful with driving: Avoid driving or operating machinery until you know how this medicine affects you. It may reduce your alertness.
  • Inform healthcare providers: Tell your dentist, surgeon, or any healthcare professional that you are taking this medicine before any medical or dental procedure. It may increase your risk of bleeding.
  • Check before taking pain relievers: Talk to your doctor before using over-the-counter pain relievers such as ibuprofen or aspirin. Taking them with this medicine may increase the risk of bleeding.
  • Get emergency help for serotonin syndrome: Seek immediate medical attention if you develop a high fever, severe agitation, hallucinations, muscle stiffness, loss of coordination, a fast heartbeat, or excessive sweating. These may be signs of a serious reaction called serotonin syndrome.

Drug-Drug Interactions

verifiedApollotooltip
  • Drugs used to treat depression or monoamine oxidase inhibitors (e.g., phenelzine or selegiline): Do not take ZOVANE 40MG TABLET with MAOIs or within 14 days of stopping them, as this can cause a life-threatening reaction.
  • Blood Thinners and NSAIDs (e.g., warfarin, ibuprofen, aspirin): Combining ZOVANE 40MG TABLET with blood thinners or pain relievers may increase your risk of bleeding.
  • Other Serotonergic Medications (e.g., triptans, tramadol, or other antidepressants): Taking this medicine with other drugs that increase serotonin levels can increase the risk of serotonin syndrome.
VilazodoneSelegiline
Critical
VilazodoneSafinamide
Critical

Drug-Drug Interactions

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VilazodoneSelegiline
Critical
How does the drug interact with Zovane 40mg Tablet:
Co-administration of Zovane 40mg Tablet is taken with Selegiline, which increases the serotonin levels (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Selegiline together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, shaking, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneSafinamide
Critical
How does the drug interact with Zovane 40mg Tablet:
Taking Safinamide with Amitriptyline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Safinamide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
VilazodoneTranylcypromine
Critical
How does the drug interact with Zovane 40mg Tablet:
Taking Zovane 40mg Tablet with Tranylcypromine can increase the risk of serotonin syndrome (a A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Tranylcypromine can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneProcarbazine
Critical
How does the drug interact with Zovane 40mg Tablet:
When Zovane 40mg Tablet is taken with Procarbazine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Procarbazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneFurazolidone
Critical
How does the drug interact with Zovane 40mg Tablet:
When Zovane 40mg Tablet is taken with Furazolidone, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Furazolidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneRasagiline
Critical
How does the drug interact with Zovane 40mg Tablet:
Taking Zovane 40mg Tablet and Rasagiline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Rasagiline together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneIsocarboxazid
Critical
How does the drug interact with Zovane 40mg Tablet:
When Zovane 40mg Tablet is taken with Isocarboxazid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Isocarboxazid together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodonePhenelzine
Critical
How does the drug interact with Zovane 40mg Tablet:
When Zovane 40mg Tablet is taken with Phenelzine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Phenelzine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneLinezolid
Critical
How does the drug interact with Zovane 40mg Tablet:
When Zovane 40mg Tablet is taken with Linezolid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Zovane 40mg Tablet with Linezolid together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneOndansetron
Severe
How does the drug interact with Zovane 40mg Tablet:
When Zovane 40mg Tablet is taken with Ondansetron, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There may be a possibility of interaction between Zovane 40mg Tablet and Ondansetron, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Food: Taking ZOVANE 40MG TABLET without food significantly lowers its absorption in your body, making it less effective.
  • Grapefruit: Avoid eating grapefruit or drinking grapefruit juice, as it may increase the levels of the medicine in your blood and lead to more side effects.
VILAZODONE HYDROCHLORIDE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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VILAZODONE HYDROCHLORIDE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking Zovane 40mg Tablet with St. John's Wort significantly increases the metabolism of Zovane 40mg Tablet. Avoid taking Zovane 40mg Tablet with St. John's Wort.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

ZOVANE 40MG TABLET is used to treat major depressive disorder.
ZOVANE 40MG TABLET contains 'vilazodone hydrochloride' which is an antidepressant. It works by restoring the levels of serotonin in the brain. Serotonin is a hormone or chemical messenger present in the brain responsible for improving energy, mood, and emotion levels.
ZOVANE 40MG TABLET may affect your blood sugar levels. So, let your doctor know that you have diabetes before taking ZOVANE 40MG TABLET. If prescribed, the doctor may advise you to check blood sugar levels while using this medicine regularly.
ZOVANE 40MG TABLET may cause side-effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). These side-effects usually resolve without requiring any treatment. However, if any of these side-effects persist or get worse, inform your doctor immediately.
It is not recommended to take ZOVANE 40MG TABLET with other monoamine oxidase inhibitors (MAOIs) (belongs to the class of antidepressants), especially within the 14 days after stopping or starting MAOIs.
ZOVANE 40MG TABLET should be used with caution in patients with alcohol abuse, seizures (fits), liver or kidney disease, bleeding disorder, glaucoma (an eye condition), and bipolar disorder as ZOVANE 40MG TABLET may worsen these conditions.
No, you should always take ZOVANE 40MG TABLET with food. Taking it on an empty stomach significantly reduces how much of the medicine your body absorbs, which can make it less effective. Talk to your doctor or pharmacist if you have trouble taking it with meals.
Clinical studies show that ZOVANE 40MG TABLET is generally weight-neutral, meaning it is less likely to cause significant weight gain or loss compared to some other antidepressants. However, individual responses can vary. Talk to your doctor or pharmacist if you are concerned about weight changes.
It is highly recommended to avoid alcohol while taking ZOVANE 40MG TABLET. Alcohol can make your depression symptoms worse and increase side effects like drowsiness, dizziness, and poor concentration. Talk to your doctor for personalised advice.
You should never stop taking ZOVANE 40MG TABLET suddenly. Stopping abruptly can cause withdrawal symptoms like dizziness, nausea, headache, and irritability. Your doctor will provide a plan for gradually decreasing your dose safely.
ZOVANE 40MG TABLET is designed in a way that may result in fewer sexual side effects compared to traditional SSRI antidepressants. However, some people may still experience them. If you notice any changes in sexual function, talk to your doctor or pharmacist.
You should consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will weigh the benefits of treating your depression against any potential risks to the baby. Talk to your doctor to make an informed decision.
Serotonin syndrome is a rare but serious condition caused by too much serotonin in the brain, especially when combining ZOVANE 40MG TABLET with other medications. Symptoms include confusion, fast heart rate, sweating, shivering, and muscle stiffness. If you experience these symptoms, seek emergency medical help immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA
Other Info - ZOV0083

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