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More about the Product

Composition :

ACYCLOVIR-400MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Zoster 400 DT Tablet

Zoster 400 DT Tablet is an oral prescription antiviral medicine used to treat infections caused by certain types of viruses. It is commonly prescribed to treat shingles, chickenpox, cold sores, and genital herpes. This medicine helps shorten the duration of the viral outbreak and reduces the severity of painful symptoms.

To get the best results, you must take Zoster 400 DT Tablet consistently and at evenly spaced intervals throughout the day as directed. You can take this medicine with or without food, though taking it with a meal can help if you have a sensitive stomach. Drinking plenty of water while taking this medication is highly recommended to keep your kidneys working safely.

While Zoster 400 DT Tablet is generally well-tolerated, some people may experience mild side effects like nausea, headache, or diarrhea. If you notice any serious reactions, such as confusion, unusual bruising, or changes in how much you urinate, you should contact your doctor right away.

Talk to your doctor before starting Zoster 400 DT Tablet if you have kidney problems, a weakened immune system, or any nerve disorders. Do not take this if you have had a severe allergic reaction to this medication or similar antiviral drugs in the past.

Let your doctor know if you are taking other medications, especially those that can affect your kidneys, as they may interact with Zoster 400 DT Tablet . If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider to discuss the safety of this treatment.

Uses of Zoster 400 DT Tablet

Your doctor may recommend Zoster 400 DT Tablet to help:

  • Shingles (Herpes Zoster): Zoster 400 DT Tablet helps treat this painful, blistering skin rash by stopping the virus from multiplying, which speeds up skin healing and reduces nerve pain.
  • Genital Herpes: Zoster 400 DT Tablet is used to treat initial and recurrent outbreaks, helping sores heal faster and reducing the frequency of future flare-ups.
  • Cold Sores (Herpes Labialis): Zoster 400 DT Tablet limits the growth of the virus around the mouth, reducing pain and helping the blisters crust over and heal more quickly.
  • Chickenpox (Varicella): Zoster 400 DT Tablet helps reduce the number of chickenpox spots and relieves fever and itching, especially when started within 24 hours of the rash first appearing.

Key Benefits

When used as directed as part of your treatment plan, Zoster 400 DT Tablet may provide the following benefits:

  • Relieves Viral Skin Symptoms: Zoster 400 DT Tablet offers significant relief from the painful, burning, and uncomfortable symptoms of viral skin infections.
  • Supports Faster Healing: By stopping the virus from multiplying, it helps your body fight off the infection more efficiently, leading to faster healing of blisters and sores.
  • Reduces Shingles Nerve Pain: Another key benefit of Zoster 400 DT Tablet is its ability to reduce the intensity and duration of nerve pain associated with shingles.
  • Helps Prevent Herpes Recurrences: For people who experience frequent genital herpes outbreaks, taking this medicine daily as a preventive measure can greatly lower the number of future episodes, helping you regain comfort and peace of mind.
Side effects of Zoster 400 DT Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Drink plenty of fluids and consider oral rehydration solutions.
  • Eat bland, easily digestible foods like bananas, rice, toast, and applesauce.
  • Avoid trigger foods like greasy, spicy, fatty, acidic, and caffeinated foods.
  • Gradually reintroduce fiber-rich foods as symptoms improve.
  • Get adequate sleep and rest.
  • Practice relaxation techniques to manage stress.
  • Maintain regular bowel habits.
  • Avoid overexertion and take breaks when needed.
  • Consult a doctor if your gastrointestinal symptoms are severe, persistent, or accompanied by fever, bloody stools, dehydration, or last for more than a few days.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Zoster 400 DT Tablet can be taken with or without food.
  • Your doctor will decide the dose and duration depending on the severity of your symptoms.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, chew, or break Zoster 400 DT Tablet , as it may affect how the medication is absorbed.

How Zoster 400 DT Tablet Works

Zoster 400 DT Tablet contains the active ingredient Acyclovir , which belongs to a class of medicines called antivirals. When you take this medicine, it enters the virus-infected cells in your body. Once inside, it is converted into an active form that specifically targets and blocks a viral protein called DNA polymerase. By blocking this essential protein, the medicine stops the virus from replicating its genetic material. Because the virus can no longer copy itself or spread to healthy cells, your body's immune system can easily clear the existing infection and heal the damaged skin.
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Alcohol

Caution

Alcohol is not known to cause any unpleasant side effects if taken along with Zoster 400 DT Tablet . But intake of alcohol with Zoster 400 DT Tablet may damage your liver. So intake of alcohol should be avoided with Zoster 400 DT Tablet .

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Pregnancy

Caution

Zoster 400 DT Tablet is a pregnancy Category B medicine. It is unknown whether Zoster 400 DT Tablet will affect pregnant women or fetus. Hence, the intake of Zoster 400 DT Tablet should be only if prescribed and under medical supervision.

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Breast Feeding

Caution

The safety of Zoster 400 DT Tablet in breastfeeding women is not known. Hence, Zoster 400 DT Tablet should only be taken if prescribed by a doctor and under medical supervision.

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Driving

Caution

Zoster 400 DT Tablet can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Zoster 400 DT Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zoster 400 DT Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Zoster 400 DT Tablet is safe if prescribed by a child specialist.

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Heart

Consult your doctor

Inform your doctor if you have heart disease before using Zoster 400 DT Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Zoster 400 DT Tablet should be given with caution to elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Zoster 400 DT Tablet

If you suspect an overdose or have taken too much of this medicine, seek emergency medical attention. Symptoms of an overdose may include extreme tiredness, agitation, confusion, or kidney problems.

Diet & Lifestyle Advise

  • Stay hydrated: Drink at least 8 to 10 glasses of water daily. This helps your kidneys process and clear the medication safely from your body, reducing the risk of kidney strain.
  • Keep affected areas clean and dry: Wash blisters gently with mild soap and water, then pat dry. This prevents secondary bacterial infections and helps the skin heal.
  • Wear loose-fitting clothing: If you have shingles or genital herpes, wear loose cotton clothes to avoid irritating the blisters and to prevent friction pain.
  • Avoid touching active sores: Do not scratch or pop the blisters, as this can spread the virus to other parts of your body or to other people. Wash your hands immediately if you touch a sore.
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Have a query?

How Soon It Starts Working

The time required for Zoster 400 DT Tablet to start to work: Zoster 400 DT Tablet ideally shows its action within 1.5 to 2 hours after administration. The time for which the effects of Zoster 400 DT Tablet last: The effect of Zoster 400 DT Tablet lasts for 9 to 12 hours.

What if you forget to take Zoster 400 DT Tablet

If you miss a dose of Zoster 400 DT Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Zoster 400 DT Tablet tablets or oral suspension at room temperature, ideally between 15°C and 25°C (59°F and 77°F).

Drug Warnings

  • Start treatment early: This medicine works best when started at the very first sign of an outbreak (such as tingling, burning, or redness) before blisters actually appear.
  • Avoid sexual contact during herpes outbreaks: If you are taking this for genital herpes, abstain from sexual activity while you have active sores or tingling, as the virus can still be transmitted even when taking medication.
  • Monitor kidney function: If you are taking this medicine long-term or are elderly, your doctor may perform regular blood tests to check how well your kidneys are working.
  • Watch for signs of dehydration: Since hydration is key for kidney safety with this drug, seek medical advice if you experience severe vomiting or diarrhea that prevents you from keeping fluids down.

Drug-Drug Interactions

verifiedApollotooltip
  • Other medicines that can affect your kidneys: Taking Zoster 400 DT Tablet with medicines like nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen or naproxen) or certain antibiotics can increase the risk of kidney damage.
  • Probenecid: This gout medicine can slow down how fast your body processes Zoster 400 DT Tablet , leading to higher levels of the antiviral in your blood and increasing the risk of side effects.
AciclovirCidofovir
Critical
AciclovirTenofovir alafenamide
Severe

Drug-Drug Interactions

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AciclovirCidofovir
Critical
How does the drug interact with Zoster 400 DT Tablet:
Co-administration of Cidofovir with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Zoster 400 DT Tablet with Cidofovir is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
AciclovirTenofovir alafenamide
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Zoster 400 DT Tablet with Tenofovir alafenamide may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Zoster 400 DT Tablet with tenofovir alafenamide can result in an interaction. However, if the benefits outweigh the risks, your doctor will prescribe them. Contact a doctor immediately if you experience symptoms such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medication without consulting your doctor.
AciclovirSirolimus
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Zoster 400 DT Tablet with Sirolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Zoster 400 DT Tablet with Sirolimus can result in an interaction, it can be taken if your doctor has advised it. However, if you experience vomiting, a decrease in hunger, irregular urine, weight gain or loss, swelling, difficulty breathing, muscle pain, or weakness, consult a doctor.
AciclovirTacrolimus
Severe
How does the drug interact with Zoster 400 DT Tablet:
Co-administration of Zoster 400 DT Tablet with tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Coadministration of Zoster 400 DT Tablet with Tacrolimus can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without first consulting a doctor.
AciclovirTenofovir disoproxil
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Zoster 400 DT Tablet with Tenofovir Disoproxil may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Zoster 400 DT Tablet with Tenofovir disoproxil can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AciclovirIodamide
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Iodamide contrast with Zoster 400 DT Tablet may increase the risk or severity of kidney injury.

How to manage the interaction:
Before undergoing any imaging procedure let your doctor know you are on Zoster 400 DT Tablet treatment.
AciclovirTizanidine
Severe
How does the drug interact with Zoster 400 DT Tablet:
Concomitant use of Zoster 400 DT Tablet with Tizanidine can increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Zoster 400 DT Tablet with Tizanidine can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, excessive sweating, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirEverolimus
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Zoster 400 DT Tablet with Everolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Zoster 400 DT Tablet with Everolimus together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirAmphotericin b
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Zoster 400 DT Tablet with Amphotericin B can increase the risk or severity of kidney disorder.

How to manage the interaction:
Taking Zoster 400 DT Tablet with Amphotericin b together can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience irregular urination, muscle ache, shortness if breath, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirMetrizamide
Severe
How does the drug interact with Zoster 400 DT Tablet:
Coadministration of Metrizamide in contrast with Zoster 400 DT Tablet may increase the risk or severity of kidney disorder.

How to manage the interaction:
Before undergoing any imaging procedure, let your doctor know you are on Zoster 400 DT Tablet treatment. Look out for signs such as vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or weakness. Consult the doctor immediately.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Zoster 400 DT Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

No. Zoster 400 DT Tablet does not cure herpes simplex (including cold sores and genital herpes) or shingles. These viruses remain in the body even after symptoms improve. However, Zoster 400 DT Tablet helps reduce pain, speeds healing of sores and rashes, shortens the duration of the infection, and may reduce the frequency of future herpes outbreaks when taken as prescribed for suppression therapy.
If you miss a dose of Zoster 400 DT Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you miss several doses, contact your doctor or pharmacist for advice.
Yes. Zoster 400 DT Tablet may cause dizziness, tiredness, or drowsiness in some people. If you experience these effects, avoid driving, operating machinery, or performing tasks that require alertness until you know how the medicine affects you. Contact your doctor if these symptoms are severe or persistent.
No, you should always complete the full course of treatment prescribed by your doctor, even if your skin clears up and you start feeling better. Stopping the medicine too early can allow the virus to continue multiplying, which may cause the infection to return. Talk to your doctor if you have concerns about your treatment duration.
Yes, you can take Zoster 400 DT Tablet with or without food. If you find that the medicine upsets your stomach or causes mild nausea, taking it with a meal or a small snack may help. Talk to your doctor if stomach discomfort continues.
Zoster 400 DT Tablet is sometimes prescribed to pregnant individuals to treat or prevent outbreaks, especially close to the delivery date. However, its safety must be carefully weighed against the benefits. Talk to your doctor if you are pregnant or planning to become pregnant before starting this medicine.
While alcohol does not directly stop Zoster 400 DT Tablet from working, drinking can cause dehydration and increase side effects like dizziness, headache, or nausea. To protect your kidneys and help your body heal from the viral infection, it is best to avoid or limit alcohol while taking this medicine. Talk to your doctor for personalized advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.4334 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Aciclovir - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.9273 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Aciclovir Aciclovir. 2007. [Accessed on 29 Jan. 2019]Check here
  6. Acyclovir [Prescribing Information]. 2005. [Accessed on 25 Jul. 2024]Check here
  7. Acyclovir [Prescribing Information]. 2019. [Accessed on 21 Oct. 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116
Other Info - ZOS0036
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