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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zoryl MV 1 Tablet is used to treat type 2 diabetes mellitus. It acts by increasing the amount of insulin released by the pancreas. Thus, prevent the blood glucose levels from rising to very high levels and keeps your diabetes under control. It may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE+VOGLIBOSE

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zoryl MV 1 Tablet

Zoryl MV 1 Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus. Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. People with type 2 diabetes either do not produce enough insulin or, if any insulin is produced, it is unable to perform its function in the body (insulin resistance).

Zoryl MV 1 Tablet is a combination of Glimepiride, Metformin and Voglibose which help control blood sugar levels. This medicine works by increasing the amount of insulin released by the pancreas. You must continue following the diet and exercise recommended for you whilst on treatment with Zoryl MV 1 Tablet .

Not everyone who is taking Zoryl MV 1 Tablet will get these side effects. The most common side effect of Zoryl MV 1 Tablet is hypoglycemia (low blood glucose levels), characterised by dizziness, sweating, hunger pangs, dry mouth and skin, etc. Other side effects include changes in taste, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Zoryl MV 1 Tablet should be taken with food to avoid an upset stomach. For optimal results, it is recommended to take it at the same time each day. For better advice, your doctor will determine the appropriate dose, which can change quickly depending on your condition. Do not skip your meals, and also carry a form of sugar with you to prevent low blood sugar levels.

Avoid taking Zoryl MV 1 Tablet if you are allergic to it. Zoryl MV 1 Tablet should not be stopped even if you feel better without consulting your doctor, as sugar levels may change. If you stop taking Zoryl MV 1 Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy) and nerve damage (neuropathy). Zoryl MV 1 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or are planning to get pregnant or breastfeed.

Uses of Zoryl MV 1 Tablet

Zoryl MV 1 Tablet is used in the treatment of Type 2 diabetes mellitus. The detailed uses of Zoryl MV 1 Tablet are as follows:

  • Management of Type 2 Diabetes: Zoryl MV 1 Tablet effectively controls blood sugar levels in adults with type 2 diabetes, regulating glucose metabolism and maintaining optimal sugar levels.
  • Enhanced Insulin Sensitivity: Zoryl MV 1 Tablet improves the body's insulin response, facilitating glucose uptake and reducing insulin resistance.
  • Prevention of Diabetes-Related Complications: Zoryl MV 1 Tablet helps to prevent long-term complications associated with diabetes, such as kidney damage, nerve damage, and vision problems.

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Directions for Use

  • Zoryl MV 1 Tablet should be taken before meals or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Zoryl MV 1 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Zoryl MV 1 Tablet contains Glimepiride, Metformin and Voglibose used to treat type 2 diabetes mellitus.
  • Metformin acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin.
  • Voglibose prevents the breakdown of complex sugars into simple sugars such as glucose in the intestine.
  • Zoryl MV 1 Tablet prevents the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.
  • Zoryl MV 1 Tablet also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), and loss of sensation in your hands and feet (diabetic neuropathy).
  • Zoryl MV 1 Tablet also helps to reduce your chance of having a heart attack or stroke.
  • Being a combination of three drugs, Zoryl MV 1 Tablet  reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.

How Zoryl MV 1 Tablet Works

Zoryl MV 1 Tablet is a combination of three antidiabetic drugs: Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Together, these prevent the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zoryl MV 1 Tablet

Do not take more than the prescribed dose of Zoryl MV 1 Tablet as it may cause overdose resulting in mild hypoglycemia (low blood sugar). If you suspect you have taken overdose or have symptoms of overdose, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor if you are allergic to Zoryl MV 1 Tablet .
  • This medicine should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Zoryl MV 1 Tablet , might develop a rare but serious condition called lactic acidosis (too much lactic acid accumulated in the blood) that can damage the working of your liver and kidneys, which are required for the elimination of excess lactic acid from the blood.
  • Before you start taking Zoryl MV 1 Tablet , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, or a low vitamin B12 level.
  • Zoryl MV 1 Tablet , when used with insulin, may extremely lower the blood sugar level, leading to a hypoglycemic condition, which can be fatal.
  • Prolonged intake of Zoryl MV 1 Tablet may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended.
  • In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention.
  • It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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MetforminIobitridol
Critical
MetforminIopanoic acid
Critical

Drug-Drug Interactions

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MetforminIobitridol
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Zoryl MV 1 Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Iopanoic acid with Zoryl MV 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Iopamidol with Zoryl MV 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIohexol
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Iohexol with Zoryl MV 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Zoryl MV 1 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Iotroxic acid with Zoryl MV 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Zoryl MV 1 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Ioversol with Zoryl MV 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Iomeprol with Zoryl MV 1 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Zoryl MV 1 Tablet:
Co-administration of Zoryl MV 1 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Zoryl MV 1 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, quarter with proteins and quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with wholegrain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Alcohol

Unsafe

Taking Zoryl MV 1 Tablet with alcohol can cause hypoglycaemia and can also lead to a rare but life-threatening condition known as lactic acidosis. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Consult your doctor

As the data around the use of Zoryl MV 1 Tablet in pregnant women is limited, the use of Zoryl MV 1 Tablet in pregnancy is unknown. Please consult your doctor for advice before using Zoryl MV 1 Tablet .

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Breast Feeding

Consult your doctor

The name is not recommended during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk. You should not take Zoryl MV 1 Tablet without a doctor's advice.

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Driving

Unsafe

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking these medications you should not drive or operate any machinery or vehicles.

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Liver

Caution

Zoryl MV 1 Tablet to be taken with caution, especially if you have a history of liver disease.

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Kidney

Caution

Zoryl MV 1 Tablet to be taken with caution, especially if you have a history of Kidney disease

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Children

Unsafe

Zoryl MV 1 Tablet is not recommended for children below the age of 18 years as the safety and effectiveness of Zoryl MV 1 Tablet has not been established in children due to limited evidence.

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Heart

Zoryl MV 1 Tablet should be used with caution if you have any cardiac problems. This medicine is contraindicated in patients with severe heart failure.

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Geriatrics

Caution

Caution should be exercised in geriatric patients while taking Zoryl MV 1 Tablet .

FAQs

Zoryl MV 1 Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellitus.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

Hypoglycaemia refers to low blood sugar levels. The symptoms of hypoglycaemia include nausea, headache, irritability, hunger, sweating, dizziness. Zoryl MV 1 Tablet can cause hypoglycaemia. Hypoglycaemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other anti-diabetic medicine along with Zoryl MV 1 Tablet . Diabetics are advised to keep a quick source of sugar like glucose tablets, honey or fruit juice with them.

Zoryl MV 1 Tablet should be avoided in patients who are allergic to any of the components or excipients of this medicine. It should be avoided in patients suffering from moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

If you feel thirsty after taking Zoryl MV 1 Tablet , it may be because of dehydration as Zoryl MV 1 Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ZOR0168

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