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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ZORTAN H TABLET is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Losartan and Hydrochlorothiazide, which helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Also, it prevents excess salt absorption in the body, preventing fluid retention. Thus, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload). In some cases, it may cause side effects such as upper respiratory infections, dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough.

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Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ZORTAN H TABLET

ZORTAN H TABLET is used to treat hypertension (high blood pressure) and reduce the risk of stroke. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

ZORTAN H TABLET is a combination of Losartan and Hydrochlorothiazide. Losartan helps to relax and widen the blood vessels (arteries) for easy blood flow. Hydrochlorothiazide prevents excess salt absorption in the body, preventing fluid retention.

You may experience certain side effects like dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough in some cases. Most of these side effects of ZORTAN H TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take ZORTAN H TABLET with food or on an empty stomach. It should be swallowed whole with a glass of water. Your doctor will advise you on how often you take your tablets based on your medical condition. Do not chew, break, or crush the medicine.

Inform your doctor if you are allergic to ZORTAN H TABLET. Do not use potassium supplements or salt substitutes unless your doctor tells you. Consult your doctor if you are pregnant or breastfeeding. Besides this, you should not use the ZORTAN H TABLET if you cannot urinate.

Uses of ZORTAN H TABLET

ZORTAN H TABLET is used in the treatment of Hypertension (high blood pressure) and prevention of stroke. The detailed uses of ZORTAN H TABLET are as follows:

  • Hypertension: ZORTAN H TABLET controls blood pressure more effectively than either drug alone
  • Stroke Prevention: ZORTAN H TABLET is used especially in patients with left ventricular hypertrophy (enlarged heart muscle).
  • Heart Failure & Cardiovascular Risk Reduction: ZORTAN H TABLET help reduce the risk of heart attack and other complications.

Directions for Use

• Take ZORTAN H TABLET with or without food as advised by your doctor. • It is advised to take ZORTAN H TABLET once daily in the morning; however, follow your doctor’s recommendation regarding the dosage and duration. • Swallow ZORTAN H TABLET as a whole with a glass of water. • Do not crush, chew or break it.

Medicinal Benefits

  • ZORTAN H TABLET contains losartan (angiotensin II receptor antagonist) and hydrochlorothiazide (a thiazide diuretic or water pill).
  • Losartan widens the blood vessels (arteries) for easy blood flow, whereas hydrochlorothiazide prevents fluid retention.
  • This medicine lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid retention).
  • This combination medication is generally used when a single medicine is unable to control high blood pressure.

How ZORTAN H TABLET Works

ZORTAN H TABLET is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of ZORTAN H TABLET

Do not take more than the prescribed dose of ZORTAN H TABLET as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • ZORTAN H TABLET should not be given to the people allergic to ZORTAN H TABLET.
  • It should be used with caution in patients who have diabetes. 
  • ZORTAN H TABLET is not recommended in conditions like low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
  • Do not consume alcohol with ZORTAN H TABLET as it may increase the risk of low blood pressure.
  • Avoid potassium supplements with ZORTAN H TABLET as they may lead to high potassium levels in the blood.
  • Regular blood tests and blood pressure monitoring are recommended while taking ZORTAN H TABLET.
  • Drink a lot of fluids, as ZORTAN H TABLET can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.
  • This medicine is not recommended for use in pregnant women, as it can cause fetal harm. Hence, inform your physician if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Zortan H Tablet:
Taking Dofetilide and Zortan H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Zortan H Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zortan H Tablet:
Taking Cisapride and Zortan H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Zortan H Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zortan H Tablet:
Coadministration of Zortan H Tablet with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Zortan H Tablet with Spironolactone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
LosartanPotassium citrate
Severe
How does the drug interact with Zortan H Tablet:
Coadministration of Zortan H Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Zortan H Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zortan H Tablet:
Coadministration of Zortan H Tablet with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.

How to manage the interaction:
Taking Zortan H Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
How does the drug interact with Zortan H Tablet:
Coadministration of Zortan H Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Zortan H Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zortan H Tablet:
Using enalapril together with Zortan H Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Enalapril with Zortan H Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
LosartanCaptopril
Severe
How does the drug interact with Zortan H Tablet:
Coadministration of Zortan H Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Zortan H Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zortan H Tablet:
Coadministration of Zortan H Tablet with Benazepril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Zortan H Tablet with Benazepril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zortan H Tablet:
Coadministration of amiloride with Zortan H Tablet may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Taking amiloride along with Zortan H Tablet may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice

How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Zortan H Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Zortan H Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Zortan H Tablet.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

You are recommended not to consume alcohol and ZORTAN H TABLET to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

ZORTAN H TABLET is not recommended during pregnancy as it may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Consult your doctor

ZORTAN H TABLET is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this.

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Driving

Unsafe

ZORTAN H TABLET causes drowsiness and dizziness, so drive only if you are alert.

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Liver

Caution

ZORTAN H TABLET to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will adjust the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Unsafe

ZORTAN H TABLET is not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Unsafe

ZORTAN H TABLET is not recommended for use in children below 18 yaers of age as the safety and efficacy are not established.

Have a query?

FAQs

ZORTAN H TABLET is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.

ZORTAN H TABLET is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

ZORTAN H TABLET can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

In case you have missed a dose of ZORTAN H TABLET, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of ZORTAN H TABLET will lead to low blood pressure.

It is not recommended to take ZORTAN H TABLET if you are pregnant as it can damage the unborn baby (may lead to fetal toxicity).

Yes, prolonged intake of ZORTAN H TABLET can cause an increase in blood potassium level. So, patients taking ZORTAN H TABLET should avoid taking supplements and food rich in potassium to avoid any unpleasant side-effect.

Yes, ZORTAN H TABLET can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking ZORTAN H TABLET. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

You should not take ZORTAN H TABLET if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, anuria (reduction or absence of urine) and pregnant women in their second or third trimesters. Besides this, avoid using ZORTAN H TABLET (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Other Info - ZOR0109

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