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Zolfen-P Tablet 10's is used to treat pain caused by various medical conditions, including rheumatoid arthritis, osteoarthritis, low back pain, periarthritis of the shoulder, cervicobrachial syndrome, postoperative, post-trauma, and post-dental extraction. It contains zaltoprofen and paracetamol. Zaltoprofen works by inhibiting the action of a chemical messenger called cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, Paracetamol acts as a mild analgesic and antipyretic, enhancing Zaltoprofen's pain-relieving action. As a result, Zolfen-P Tablet 10's effectively relieves pain.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Aeon Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Zolfen-P Tablet 10's

Zolfen-P Tablet 10's is an oral prescription medication used to manage acute and chronic pain associated with inflammatory conditions. It is commonly prescribed to treat swelling, stiffness, and discomfort in the joints and muscles.

For the best results, take Zolfen-P Tablet 10's exactly as prescribed by your doctor, keeping your daily schedule consistent. It is highly recommended to take this medicine with or immediately after a meal to protect your stomach lining. Alongside taking this medication, incorporating gentle, low-impact physical therapy and staying hydrated can significantly support your physical recovery.

Like most pain-relief medications, Zolfen-P Tablet 10's can cause mild stomach upset or dizziness in some patients. While these symptoms are usually temporary, you should stop taking the medicine and contact your doctor immediately if you notice serious issues like dark, tarry stools or severe, sharp abdominal pain.

Talk to your doctor before starting Zolfen-P Tablet 10's if you have a history of high blood pressure, asthma, or kidney and liver problems. Do not take this if you currently have active stomach ulcers, severe heart failure, or if you are in the late stages of pregnancy.

This medication can interact with other treatments, such as blood thinners or other anti-inflammatory drugs, which may increase your risk of bleeding. You should avoid drinking alcohol while taking Zolfen-P Tablet 10's because it can significantly increase the strain on your liver and raise the risk of stomach irritation. If you are pregnant, breastfeeding, or managing multiple health conditions as an older adult, consult your doctor to ensure this medicine is safe for you.

Uses of Zolfen-P Tablet 10's

Zolfen-P Tablet 10's is used to relieve pain and inflammation in conditions like rheumatoid arthritis and osteoarthritis. The detailed uses of Zolfen-P Tablet 10's are as follows:

  • Osteoarthritis: Helps reduce persistent pain, stiffness, and localised swelling in the affected weight-bearing joints.
  • Rheumatoid arthritis: Eases joint inflammation, warmth, and morning stiffness caused by autoimmune joint conditions.
  • Post-operative pain: Manages acute surgical wounds and tissue discomfort during the early recovery phase.
  • Musculoskeletal injuries: Relieves sharp pain and swelling resulting from muscle strains, sprains, or backaches.

Key Benefits

Zolfen-P Tablet 10's provides reliable, targeted relief by addressing both the root cause of inflammation and the pain signals sent to your brain.
Benefits may include:

  • This dual approach helps you manage moderate-to-severe discomfort more effectively than single-ingredient alternatives.
  • By lowering inflammation and easing stiff joints, this medicine helps restore your physical mobility. This allows you to perform daily tasks, engage in physical therapy, and move around with much greater comfort.
  • It supports a smoother, more comfortable recovery process after surgeries or acute injuries, helping you return to your normal routine without being held back by severe pain.
Side effects of Zolfen-P Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.

Directions for Use

  • Take Zolfen-P Tablet 10's with food to reduce stomach upset or gastrointestinal side effects.
  • Recommended to take it once daily in the morning or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Zolfen-P Tablet 10's Works

Zolfen-P Tablet 10's works through the combined action of its two active ingredients, which attack pain and swelling from two different pathways. Zaltoprofen: It is a non-steroidal anti-inflammatory drug (NSAID), which works directly at the site of pain or injury by blocking specific chemical messengers called prostaglandins. These messengers are responsible for triggering swelling, redness, heat, and pain. By stopping their production, this ingredient significantly decreases local inflammation. Paracetamol: It is a pain reliever and fever reducer that works mainly in the brain and spinal cord (central nervous system). Although its exact mechanism is not fully understood, it is thought to reduce pain by modulating pain-processing pathways, including the serotonin and endocannabinoid systems, helping decrease the perception of pain without significantly reducing inflammation.
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Alcohol

Caution

Alcohol consumption should be avoided while on Zolfen-P Tablet 10's treatment.

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Pregnancy

Caution

Zolfen-P Tablet 10's should be used during pregnancy only after weighing the benefits and risks as suggested by the physician.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Zolfen-P Tablet 10's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Zolfen-P Tablet 10's may affect driving ability as it causes headaches, dizziness or drowsiness. Avoid driving after taking Zolfen-P Tablet 10's until you are alert.

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Liver

Caution

Zolfen-P Tablet 10's should be used with caution in patients with liver disease. If you have liver problems, inform your doctor before taking Zolfen-P Tablet 10's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Zolfen-P Tablet 10's should be used with caution in patients with kidney disease. If you have liver problems, inform your doctor before taking Zolfen-P Tablet 10's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Caution

The safety and efficacy of Zolfen-P Tablet 10's in children and adolescents aged below 18 years have not been established.

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Heart

Caution

Zolfen-P Tablet 10's may require caution in patients with heart problems. Therefore, please consult your doctor if you have any heart-related conditions before using Zolfen-P Tablet 10's.

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Geriatrics

Safe if prescribed

Zolfen-P Tablet 10's is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Zolfen-P Tablet 10's

If you suspect an overdose or have accidentally taken too much Zolfen-P Tablet 10's, seek emergency medical care immediately. Do not wait for symptoms of toxicity, such as severe nausea, vomiting, or breathing difficulties, to appear.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys filter and process the medication safely.
  • Protect your stomach: Avoid eating heavily spiced or acidic foods while on this medication, as they can worsen mild stomach irritation.
  • Avoid alcohol and smoking: Refrain from drinking alcohol and smoking, as both can significantly increase your risk of developing stomach ulcers and bleeding.
  • Gentle movement: Engage in low-impact activities like walking or light stretching to prevent joint stiffness without putting excess stress on your body.
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How Soon It Starts Working

The time required for Zolfen-P Tablet 10's to start to work: Zolfen-P Tablet 10's ideally shows its action within 30 minutes after administration. The time for which the effects of Zolfen-P Tablet 10's last: The duration of action for Zolfen-P Tablet 10's is clinically unknown.

What if you forget to take Zolfen-P Tablet 10's

If you miss a dose, take it as soon as you remember, provided it is taken with food. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Zolfen-P Tablet 10's at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place away from direct sunlight and moisture.

Drug Warnings

  • Who should not take this medicine: Do not take Zolfen-P Tablet 10's if you have an active stomach ulcer or stomach bleeding, severe liver or kidney disease, uncontrolled heart failure, are in the third trimester of pregnancy, or have a history of asthma or severe allergic reactions triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs). Talk to your doctor before taking this medicine if you have any of these conditions.
  • Check the packaging before use: Inspect the blister packaging before use; do not take the tablet if the foil is punctured or damaged.
  • Take with food: Always take Zolfen-P Tablet 10's with or immediately after a meal to minimise the risk of stomach irritation.
  • Avoid combining with other pain medicines: Do not combine this medicine with other cold, flu, or over-the-counter pain medications without checking with a pharmacist first.
  • Inform your healthcare provider before procedures: If you are scheduled for any surgical or dental procedures, inform your healthcare provider that you are taking Zolfen-P Tablet 10's, as it may affect blood clotting times.
  • Be cautious when driving: Avoid driving or operating heavy machinery if you feel dizzy or lightheaded after taking your dose.
  • Avoid prolonged use without medical supervision: Do not use Zolfen-P Tablet 10's for longer than prescribed. Long-term use of NSAIDs such as zaltoprofen may increase the risk of stomach ulcers, kidney problems, heart attack, stroke, and worsening heart failure. Your doctor may recommend regular check-ups if prolonged treatment is necessary.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): May severely increase the risk of internal bleeding.
  • Other anti-inflammatory medicines or oral steroids: May increase the risk of stomach ulcers, bleeding, or stomach irritation.
  • Certain blood pressure medicines: May reduce the blood pressure-lowering effects of some medicines used to treat high blood pressure.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • High-fat meals: Taking this medication with very high-fat meals may slow down its absorption and delay pain relief, though it should still always be taken with some food to avoid stomach discomfort.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Zolfen-P Tablet 10's is used to treat Pain in rheumatoid arthritis, osteoarthritis, low back pain, periarthritis of shoulder, cervicobrachial syndrome, postoperative, post-trauma, and post-dental extraction.
Zolfen-P Tablet 10's contains Zaltoprofen and Paracetamol. Zaltoprofen works by inhibiting the action of a chemical messenger called cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, Paracetamol acts as a mild analgesic and antipyretic, enhancing Zaltoprofen's pain-relieving action. As a result, Zolfen-P Tablet 10's effectively relieves pain.
No, do not take Zolfen-P Tablet 10's until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen, or gallbladder problems. Your back pain may be due to kidney stones, pancreas swelling, or, in women, pelvic disorders. Your arm pain (especially the left arm) may be due to a heart attack (myocardial infarction).
No, Zolfen-P Tablet 10's should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For the best results of Zolfen-P Tablet 10's, take it in doses and duration mentioned by your doctor.
Yes, Zolfen-P Tablet 10's is a short-term medication, and if you feel better, you can stop taking Zolfen-P Tablet 10's by consulting your doctor.
NSAIDs are most commonly used to treat mild to moderate pain. NSAIDs pose no risk of addiction, and depending on the severity of the pain, they may eliminate the need for stronger medications.
The common side effects of Zolfen-P Tablet 10's include nausea, drowsiness, dizziness, headache, stomach discomfort, stomachache, diarrhoea, heartburn, and anaphylactic-like symptoms (allergic reactions). Most of these side effects do not require medical attention and will resolve gradually. However, if the side effects persist or worsen, please consult your doctor.
Do not take your regular painkillers with Zolfen-P Tablet 10's unless advised by your doctor. Zolfen-P Tablet 10's contains paracetamol and zaltoprofen. Combining it with other painkillers may lead to potential interactions or side effects, such as liver or kidney damage and stomach irritation. Always check with your doctor before combining medications to ensure safe and effective treatment.
Zolfen-P Tablet 10's is not habit-forming or addictive in most cases. However, long-term use or high doses of Zolfen-P Tablet 10's may lead to physical dependence in rare instances.
Zolfen-P Tablet 10's is not a steroid. It contains paracetamol, a pain reliever and fever reducer, and zaltoprofen, a non-steroidal anti-inflammatory drug (NSAID) that helps reduce inflammation and pain. Neither of these ingredients is a steroid.
Zolfen-P Tablet 10's should only be used in children under a doctor's guidance, as its safety and effectiveness in children under 18 have not been established. If your 12-year-old kid has back pain, it is essential to consult a doctor first to ensure the dosage is appropriate and safe based on their age and weight, especially considering any potential side effects or interactions. Always consult a doctor before using any pain management treatments for children.
Yes, Zolfen-P Tablet 10's is generally safe for elderly people when taken within the recommended dosage for pain and inflammation relief. However, caution should be exercised with the dosage, as older adults may have reduced liver or kidney function. Zolfen-P Tablet 10's may worsen liver damage (from paracetamol) or cause stomach irritation/bleeding (from zaltoprofen), especially in those with pre-existing liver or kidney conditions. Before using this medication, always inform your doctor about your medical history and any ongoing medications.
No, it is highly recommended to take Zolfen-P Tablet 10's with or immediately after a meal to protect your stomach lining from irritation. Talk to your doctor or pharmacist if you experience persistent stomach issues.
You should avoid alcohol while using this medicine. Combining alcohol with Zolfen-P Tablet 10's increases your risk of liver damage and stomach bleeding. Talk to your doctor for further guidance.
This medicine is generally not recommended during pregnancy, especially during the third trimester, as it may harm the unborn baby. Talk to your doctor to discuss safer alternatives.
Avoid taking this medicine with other NSAIDs (like ibuprofen) or pain-relief products unless explicitly directed by your physician, as this can increase the risk of severe side effects. Talk to your doctor or pharmacist.
Some individuals may experience mild dizziness or drowsiness after taking this medication. If you feel dizzy, avoid driving, cycling, or operating machinery. Talk to your doctor if this symptom persists.
Take the missed dose as soon as you remember with some food. If your next dose is only a few hours away, skip the missed dose and resume your regular schedule. Talk to your pharmacist if you are unsure.

Disclaimer

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Reference

  1. National Health Service (NHS). Paracetamol For Adults - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. File Upload 130293. [Accessed on 02 Jun. 2026]Check here
  3. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Zott P Tablet

Country of origin

India

Manufacturer/Marketer address

Plot No 21, Door 2, Velu Naicker Street,Kattabomman Street,Venkateshwara1St Main Road, Ramapuram, Chennai, Tamil Nadu 600089
Other Info - ZOL0370
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