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compositionComposition:AMLODIPINE-5MG+ATORVASTATIN-10MG
prescription
Prescription Medicine
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ZIVAST AM TABLET is used to treat high blood pressure, chest pain, and clogged arteries. It contains Atorvastatin and Amlodipine which work by blocking liver enzymes, causing the liver to make less cholesterol and relaxing blood vessels, thereby improving blood flow and lowering the blood pressure. This medicine may sometimes cause side effects such as nausea, stomach pain, headache, sleepiness, constipation, muscle pain and tiredness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+ATORVASTATIN-10MG

Manufacturer/Marketer :

FDC Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ZIVAST AM TABLET

The medication ZIVAST AM TABLET is prescribed to manage high blood pressure and high cholesterol levels at the same time. By addressing both conditions, this medicine helps lower your overall risk of cardiovascular events, such as heart attacks and strokes. It serves as a dual-action therapy for individuals who require treatment for both hypertension and elevated lipids.

To achieve the best results, you should take ZIVAST AM TABLET consistently at the same time each day, as directed by your doctor. You can take this tablet with or without food, making it easy to fit into your daily routine. Combining this treatment with a heart-healthy diet and regular exercise plays a crucial role in managing your cardiovascular health.

While taking ZIVAST AM TABLET, you may experience mild side effects, such as swelling in your ankles, headache, or mild stomach upset. However, if you develop severe or unexpected symptoms, such as unexplained muscle pain, severe weakness, or yellowing of your eyes and skin, you should contact your doctor immediately.

Before starting ZIVAST AM TABLET, tell your doctor if you have a history of liver problems, kidney disease, or thyroid issues. Do not take this if you are pregnant, planning to become pregnant, breastfeeding, or have active liver disease. Your doctor will help determine if this medication is safe and appropriate for your specific health profile.

Certain medications, heavy alcohol use, and smoking can interact with ZIVAST AM TABLET, potentially reducing its effectiveness or increasing the risk of liver damage and muscle problems. Elderly individuals should consult their healthcare provider, as they may be more sensitive to the effects of this medicine. Always discuss your complete lifestyle habits and list of medications with your pharmacist or doctor.

Uses of ZIVAST AM TABLET

ZIVAST AM TABLET is used in the treatment of High blood pressure (hypertension), Chest pain (angina), and Coronary artery disease (clogged arteries). The detailed uses of ZIVAST AM TABLET are as follows:

  • High Blood Pressure (Hypertension): ZIVAST AM TABLET helps relax the blood vessels, which lowers blood pressure and improves blood flow throughout your body.
  • High Cholesterol (Hyperlipidemia): This medicine helps lower 'bad' cholesterol (LDL) and triglycerides while raising 'good' cholesterol (HDL) in your blood.
  • Prevention of Heart Attacks and Strokes: By simultaneously controlling blood pressure and cholesterol, it reduces the buildup of fatty deposits in your arteries, lowering the risk of life-threatening cardiovascular events.

Key Benefits

Taking ZIVAST AM TABLET every day helps manage both high blood pressure and high cholesterol, two major risk factors for heart disease and stroke. By controlling these conditions together, it supports long-term cardiovascular health and helps reduce the risk of future complications. Benefits may include:

  • Two-in-One Convenience: Combines blood pressure and cholesterol treatment into a single daily tablet, reducing the number of pills you need to take and making it easier to follow your treatment plan.
  • Protects Your Heart and Blood Vessels: Helps maintain healthy blood pressure and cholesterol levels, reducing strain on your heart and lowering the risk of plaque buildup in the arteries.
  • Supports Vital Organ Health: By improving blood flow and reducing cardiovascular risk, it helps protect important organs such as the heart, brain, and kidneys from long-term damage.
  • Lowers the Risk of Serious Cardiovascular Events: Regular use, along with a healthy lifestyle, helps reduce the risk of heart attack, stroke, and other cardiovascular complications.
  • Promotes Better Long-Term Health: Consistent treatment helps you stay in control of your cardiovascular health, giving you greater confidence and peace of mind about your future well-being.
Side effects of Zivast Am Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Directions for Use

  • ZIVAST AM TABLET can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow ZIVAST AM TABLET as a whole with a glass of water.
  • Do not crush, break, or chew it.

How ZIVAST AM TABLET Works

ZIVAST AM TABLET is a combination of Atorvastatin and Amlodipine. Amlodipine: Relaxes and widens your blood vessels, allowing blood to flow more easily and lowering blood pressure. Atorvastatin: Reduces the production of 'bad' cholesterol (LDL) and triglycerides in the liver while helping remove excess cholesterol from the blood. Together: They lower blood pressure, reduce cholesterol buildup in the arteries, and help decrease the risk of heart attack and stroke.
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increases blood pressure.

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Pregnancy

Unsafe

ZIVAST AM TABLET is contraindicated and is unsafe to use during pregnancy since it has harmful effects on the foetus. If the patient becomes pregnant while using ZIVAST AM TABLET, please discontinue immediately, and you should be aware of the potential risks to the foetus. Please consult your doctor if you are planning to conceive or already pregnant before starting ZIVAST AM TABLET.

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Breast Feeding

Unsafe

ZIVAST AM TABLET is contraindicated and not recommended for use if you are lactating, since it passes through the breast milk and can affect nursing infants. Please consult your doctor before starting ZIVAST AM TABLET.

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Driving

Caution

ZIVAST AM TABLET may cause dizziness, headaches, nausea or tiredness that can affect your ability to drive. Do not drive or operate machinery if you experience such symptoms. Please seek medical attention if these symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing ZIVAST AM TABLET.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing ZIVAST AM TABLET.

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Children

Caution

Usage and dosing of ZIVAST AM TABLET in children are to be determined by the doctor. The doctor decides the dosing schedule based on the child's age and weight.

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Heart

Safe if prescribed

ZIVAST AM TABLET is generally safe for heart patients when used under medical supervision. However, it is important to consult your doctor if you have any concerns or underlying conditions.

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Geriatrics

Consult your doctor

Please consult your doctor before using ZIVAST AM TABLET in elderly people. Your doctor will prescribe ZIVAST AM TABLET if the benefits outweigh the risk.

What if I have taken an overdose of ZIVAST AM TABLET

If you take more than your prescribed dose, seek immediate medical attention or contact a poison control center right away. An overdose can cause your blood pressure to drop dangerously low, leading to severe dizziness, confusion, or fainting.

Diet & Lifestyle Advise

  • Adopt a heart-healthy diet low in saturated fats, trans fats, and sodium (salt) to actively support blood pressure and cholesterol control.
  • Strictly avoid grapefruit and grapefruit juice, as they contain compounds that can dangerously raise the level of this medication in your blood and increase the risk of side effects.
  • Engage in moderate-intensity aerobic exercise, such as brisk walking, cycling, or swimming, for at least 150 minutes per week, as approved by your doctor.
  • Limit your alcohol consumption, as mixing alcohol with this medication increases the risk of liver damage and can affect your blood pressure control.
  • If you smoke, seek resources to help you quit; smoking damages blood vessels and severely undermines the heart-protective benefits of this medication.
health query

Have a query?

How Soon It Starts Working

The time required for ZIVAST AM TABLET to start to work: ZIVAST AM TABLET ideally shows its action within 6 to 12 hours after administration. The time for which the effects of ZIVAST AM TABLET last: The effect of ZIVAST AM TABLET lasts for 24 hours.

What if you forget to take ZIVAST AM TABLET

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose entirely and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store the tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).•Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Monitor Your Muscles: Pay close attention to any sudden, unexplained muscle aches, tenderness, or weakness. Contact your doctor immediately if these occur, as they can indicate a rare but serious muscle breakdown.
  • Get Routine Blood Work: Keep all appointments for blood tests. Your doctor will need to run regular blood tests to check your liver function and monitor your cholesterol levels.
  • Check Before Starting New Meds: Always consult your pharmacist or doctor before starting any new over-the-counter drugs, herbal supplements, or prescription medicines, as many can interact with this treatment.
  • Rise Slowly: To prevent dizziness or fainting caused by a sudden drop in blood pressure, take your time when standing up from a sitting or lying position.
  • Verify Your Pills: Always inspect your tablets before taking them; do not take them if they appear discolored, chipped, or if the packaging is damaged.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain Antifungals and Antibiotics (e.g., ketoconazole, erythromycin): May significantly increase the level of this medicine in your body, raising the risk of severe muscle side effects.
  • Other Cholesterol Medicines (e.g., gemfibrozil, fenofibrate): Can increase the risk of muscle pain and serious muscle damage when taken together.
  • Heart Medications (e.g., digoxin): May alter how your body processes these drugs, requiring dose adjustments or careful monitoring.
Atorvastatin + AmlodipinePosaconazole
Critical
Atorvastatin + AmlodipineTelaprevir
Critical

Drug-Drug Interactions

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Atorvastatin + AmlodipinePosaconazole
Critical
How does the drug interact with Zivast Am Tablet:
Taking atorvastatin with Posaconazole can increase the blood levels of atorvastatin. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with atorvastatin, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Atorvastatin + AmlodipineTelaprevir
Critical
How does the drug interact with Zivast Am Tablet:
Taking Telaprevir and Atorvastatin can increase the blood levels of atorvastatin.

How to manage the interaction:
The combined use of Telaprevir and Atorvastatin is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Atorvastatin + AmlodipineIndinavir
Severe
How does the drug interact with Zivast Am Tablet:
Taking atorvastatin with indinavir may raise atorvastatin levels in the blood.

How to manage the interaction:
Taking atorvastatin and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
Atorvastatin + AmlodipineErlotinib
Severe
How does the drug interact with Zivast Am Tablet:
Coadministration of Erlotinib with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Erlotinib with Atorvastatin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Atorvastatin + AmlodipineFosphenytoin
Severe
How does the drug interact with Zivast Am Tablet:
When Amlodipine is taken with Fosphenytoin, it may decrease the blood levels of Amlodipine, which may make Amlodipine less effective.

How to manage the interaction:
Although taking Amlodipine and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
Atorvastatin + AmlodipineLenalidomide
Severe
How does the drug interact with Zivast Am Tablet:
Coadministration of atorvastatin with lenalidomide can increase the risk of rhabdomyolysis (a rare condition that results in skeletal muscle tissue damage).

How to manage the interaction:
Although there is an interaction between atorvastatin and lenalidomide, it can be taken if a doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness accompanied by fever, dark-coloured urine, or light-coloured stools, consult a doctor immediately. breath. Do not discontinue any medications without consulting a doctor.
Atorvastatin + AmlodipineRifapentine
Severe
How does the drug interact with Zivast Am Tablet:
Coadministration of Amlodipine and Rifapentine may significantly reduce the blood levels of amlodipine, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amlodipine and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Atorvastatin + AmlodipineAmprenavir
Severe
How does the drug interact with Zivast Am Tablet:
Using atorvastatin together with amprenavir may significantly increase the blood levels of atorvastatin.

How to manage the interaction:
Although taking Atorvastatin and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes,make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Atorvastatin + AmlodipineDolasetron
Severe
How does the drug interact with Zivast Am Tablet:
Using dolasetron together with amlodipine can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amlodipine and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
Atorvastatin + AmlodipineSimeprevir
Severe
How does the drug interact with Zivast Am Tablet:
Using atorvastatin together with simeprevir may significantly increase the blood levels of atorvastatin.

How to manage the interaction:
Although taking Atorvastatin and Simeprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Contains compounds that block the breakdown of this medicine in your gut, leading to dangerously high levels of the drug in your body and increasing the risk of side effects.
AMLODIPINE-5MG+ATORVASTATIN-10MGFruit juices
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+ATORVASTATIN-10MGFruit juices
Moderate
Common Foods to Avoid:
Cranberry Juice, Grapefruit Juice, Noni Juice, Orange Juice, Pineapple Juice, Pomegranate Juice

How to manage the interaction:
Consumption of grape juice can increase the blood levels of atorvastatin and causes side effects. Avoid taking grape juice with atorvastatin as it can lead to an interaction, You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, Do not stop using any medications without a doctor's advice.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CARDIOVASCULAR AGENTS]

FAQs

ZIVAST AM TABLET is used to treat high blood pressure, chest pain (angina) and coronary artery disease (clogged arteries).
ZIVAST AM TABLET lowers the bad cholesterol levels and increases good cholesterol levels in the blood, preventing fat accumulation in blood vessels. It also decreases the blood pressure by widening the blood vessels and thus pumping blood to the heart. Thereby, ZIVAST AM TABLET helps treat high blood pressure, stroke, chest pain (angina) and coronary artery disease (clogged arteries).
Let your doctor know if you have any kidney/liver diseases, muscle pain, diabetes, thyroid disorders, alcohol use and heart problems (aortic/mitral stenosis) before taking ZIVAST AM TABLET. Also please inform your doctor if you have any medical issues before commencing ZIVAST AM TABLET.
It is advised to limit or avoid the intake of foods high in fat or cholesterol while using ZIVAST AM TABLET. This kind of foods may decrease the efficacy of ZIVAST AM TABLET. Also please avoid taking grapefruit and its products since it may produce unwanted effects with ZIVAST AM TABLET. Red yeast rice products are also not recommended while using ZIVAST AM TABLET since they may increase muscle and liver problems.
Nitroglycerine is a blood pressure-lowering agent so if you are using this, let your doctor know about this before using ZIVAST AM TABLET.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Stopping ZIVAST AM TABLET abruptly can lead to adverse effects, such as increased heart rate, or worsening of your condition. Consult your doctor before stopping the medication.
Inform your doctor if you are due to undergo any surgery or dental procedure. Regular ECG checks and monitoring cholesterol levels (HDL, LDL) through blood tests are also recommended. Avoid alcohol intake while using ZIVAST AM TABLET since it may lead to increased blood pressure and further worsening of side effects.
Before taking ZIVAST AM TABLET, inform your doctor about your medical history, allergies, and current medications. Let the doctor know if you are pregnant or breastfeeding.
The common side effects of ZIVAST AM TABLET include nausea, stomach pain, headache, sleepiness, ankle swelling, flushing (warm sensation in the face, ears, neck, and trunk), palpitations (pounding heartbeat), constipation, muscle pain, and tiredness. These side effects do not occur in everyone using ZIVAST AM TABLET and may vary individually. If you notice any side effects that are not manageable, it is advised to consult your doctor.
Do not take ZIVAST AM TABLET if you are pregnant, planning to become pregnant, or breastfeeding. This medication can harm an unborn baby or pass into breast milk. If you become pregnant while taking this medicine, stop taking it immediately and talk to your doctor.
Grapefruit and grapefruit juice interfere with the enzymes that break down this medication in your digestive tract. This can cause the drug levels in your blood to rise, which increases the risk of side effects like muscle pain or liver issues. Talk to your doctor if you have questions about your diet.
If you experience unexplained muscle pain, tenderness, or weakness—especially if you also have a fever or feel generally unwell—contact your doctor right away. This can be a sign of a rare but serious muscle condition. Talk to your doctor before stopping the medication.
Yes, you can take ZIVAST AM TABLET at any time of day, with or without food. However, it is highly recommended to take it at the same time every day to keep a steady amount of the medicine in your body. Talk to your doctor to find the best routine for you.
Yes, this medication works best when paired with a heart-healthy diet low in saturated fats and sodium. The medicine is meant to support, not replace, positive lifestyle and dietary changes. Talk to your doctor or a dietitian for personalized nutritional advice.
Yes, ZIVAST AM TABLET can sometimes cause dizziness, especially when you first start taking it or when your doctor is adjusting the dose. To prevent this, try rising slowly from a sitting or lying position. If the dizziness persists or is severe, talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

FDC LIMITED, B-8, MIDC Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra
Other Info - ZIV0016
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