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  3. Zitfix-M Gel 25 gm

Zitfix-M Gel 25 gm, Pack of 1 GEL
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zitfix-M Gel 25 gm is used to treat acne. It contains Metronidazole and Nicotinamide that help treat acne by preventing or stopping bacterial growth. In some cases, this medicine may cause side effects such as dry skin and application site reactions (irritation, burning, redness, and itching). Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions
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Composition :

METRONIDAZOLE-0.75%W/W + NICOTINAMIDE-4%W/W

Manufacturer/Marketer :

Prosit Healthcare Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Zitfix-M Gel 25 gm

Zitfix-M Gel 25 gm is used to treat acne. Acne or acne vulgaris is a long-term skin problem caused when hair follicles become plugged with oil and dead skin cells. It leads to the formation of blackheads, whiteheads, pimples, oily skin and a scar on the uppermost layer of the skin (epidermis).

Zitfix-M Gel 25 gm is composed of two medicines: Metronidazole and Nicotinamide. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne. Together, they effectively help in treating acne by preventing or stopping bacterial growth.

Use Zitfix-M Gel 25 gm as prescribed by your doctor. Your doctor will recommend how often you take Zitfix-M Gel 25 gm based on your medical condition. Some people may experience dry skin and application site reactions such as irritation, burning, redness, and itching). Most of these side effects of Zitfix-M Gel 25 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Zitfix-M Gel 25 gm should not be taken if you are allergic to Zitfix-M Gel 25 gm or any other contents present in it. Avoid unnecessary and prolonged use of Zitfix-M Gel 25 gm as it causes unpleasant side effects. If you are pregnant or a nursing mother, you are advised to consult a doctor before using Zitfix-M Gel 25 gm. Zitfix-M Gel 25 gm should not be used for children less than 18 years of age as the safety and efficacy of Zitfix-M Gel 25 gm for children have not been established. Zitfix-M Gel 25 gm has no known effects on the ability to drive and use machines.

Uses of Zitfix-M Gel 25 gm

Treatment of Acne.

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Take a small amount of Zitfix-M Gel 25 gm on the fingertip and apply it as a thin layer on the clean and dry affected area as advised by your doctor.• Zitfix-M Gel 25 gm is only for external use. Do not apply Zitfix-M Gel 25 gm on the broken skin or wounds.

Medicinal Benefits

Zitfix-M Gel 25 gm is composed of two medicines namely: metronidazole and nicotinamide. Zitfix-M Gel 25 gm is primarily used to treat acne. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a synthetic form of Vitamin B3, that stimulates ceramide (fats found on the uppermost layer of the skin) synthesis and improves the epidermal permeability barrier functions, making skin look supple and soft. This combination of Zitfix-M Gel 25 gm is thus efficient for treating acne.

How Zitfix-M Gel 25 gm Works

Zitfix-M Gel 25 gm is composed of two medicines: Metronidazole and Nicotinamide. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne. Together, they effectively help in treating acne by preventing or stopping bacterial growth.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Zitfix-M Gel 25 gm
  • Moisturize frequently with thick, broad-spectrum moisturizers containing sunscreen.
  • Use warm water for short baths, and gentle cleansers.
  • Pat dry and apply moisturizer immediately.
  • Use a humidifier to add moisture to the air, and choose breathable fabrics like cotton and silk.
  • Wash clothes with fragrance-free detergents to minimize irritation.
  • After taking a shower or bath, apply a moisturizer to damp skin.
  • Use petroleum jelly or other thick emollients.
  • Use a hypoallergenic, fragrance-free moisturizer 2 to 3 times a day or as frequently as required.
  • Exfoliate your skin gently using a pumice stone or slightly abrasive sponge.
  • Do not scrub your skin.
  • Avoid hot showers or baths. Instead take short, warm showers or baths.
  • Use mild soap or skin cleansers with added moisturizer.
  • Drink lots of water.
  • Use sunscreen and wear protective clothing while going out to protect yourself from sun damage.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
  • Clean the affected area with soap and water.
  • Apply a cold compress on the affected area for relief.
  • Avoid scratching the affected area.
  • Inform your doctor about the reaction so they can adjust your treatment plan and suggest alternative medications.
  • Get immediate medical attention if symptoms persist or worsen.
  • Consult a healthcare professional to diagnose the skin infection and receive appropriate treatment.
  • Follow your doctor's instructions for treatments including creams, ointments, or antibiotics to stop the spread of germs.
  • Avoid scratching to help stop further infection and irritation.
  • Particularly after handling the affected region, wash your hands frequently.
  • To stop the spreading of infection, avoid sharing personal items including towels, clothes, and makeup.
  • Keep your skin moist to avoid dryness and irritations.
  • If your symptoms worsen or don't change, let your doctor know as they provide medical attention.
  • Tell your doctor about the excessive oiliness so they can adjust your medication or offer advice.
  • Your doctor may recommend alternative medications with fewer side effects on oil production.
  • Wash your skin twice a day with a gentle cleanser to remove excess oil and dirt.
  • Choose oil-free, non-comedogenic products to prevent clogged pores.
  • Use clay masks to absorb excess oil and cleanse the skin.

What if I have taken an overdose of Zitfix-M Gel 25 gm

Though overdose is unlikely due to low systemic absorption, it is advised to avoid exceeding the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Zitfix-M Gel 25 gm is meant for only topical use only and not for oral, ophthalmic or intravaginal use. You should not use a Zitfix-M Gel 25 gm if your skin is very sensitive or allergic to Zitfix-M Gel 25 gm. Do not apply Zitfix-M Gel 25 gm on the cut, scraped, sunburned or eczema-affected skin part. Accidently Zitfix-M Gel 25 gm gets into your eyes, immediately rinse your eyes with water thoroughly and contact your doctor immediately if the irritation persists. Inform your doctor if your skin conditions do not improve. Zitfix-M Gel 25 gm may take time to treat acne, so do not apply dosage more than prescribed for better and faster results. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Zitfix-M Gel 25 gm. Zitfix-M Gel 25 gm should not be used for children less than 18 years of age as safety and efficacy of Zitfix-M Gel 25 gm for children has not established. Zitfix-M Gel 25 gm has no known effects on the ability to drive and using machines.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Avoid fried food or oil food and drink plenty of water

  • It is advised to avoid unnecessary exposure to the sun.

  • In case, it is necessary to go out in the sun, use sunscreen.

  • Do not itch or scratch the infected area.

  • Use moisturizer to prevent the occurrence of side effects

  • Exercise regularly to reduce stress 

Habit Forming

No

Therapeutic Class

ANTIACNE

Zitfix-M Gel 25 gm Substitute

Substitutes safety advice
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Alcohol

Caution

There are no interactions found with Zitfix-M Gel 25 gm pertaining to alcohol. However, it is advised to avoid alcohol for a speedy recovery.

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Pregnancy

Caution

Zitfix-M Gel 25 gm should be used for pregnant women unless if clearly needed. Consult with your doctor before using Zitfix-M Gel 25 gm.

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Breast Feeding

Caution

Zitfix-M Gel 25 gm should be used for pregnant women unless if clearly needed. Consult with your doctor before using Zitfix-M Gel 25 gm.

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Driving

Safe if prescribed

Zitfix-M Gel 25 gm usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Zitfix-M Gel 25 gm to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zitfix-M Gel 25 gm to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Zitfix-M Gel 25 gm should not be used for children less than 18 years of age as safety and efficacy of Zitfix-M Gel 25 gm for children has not established.

FAQs

Zitfix-M Gel 25 gm is used to treat acne, a skin problem caused when hair follicles become plugged with oil and dead skin cells.

Zitfix-M Gel 25 gm is composed of two medicines namely: Metronidazole and nicotinamide. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. On the other hand, nicotinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne. Together they effectively help in treating acne.

Dry skin is the most common side effect of Zitfix-M Gel 25 gm. Avoid alcohol-based products and use skin moisturizers to avoid dryness.

It is advised to keep and store this medicine in the container or the pack in which it came in and keep it tightly closed. Keep away from pets, children and other people.

Yes, you can do makeup, but you have to choose the products cautiously. Avoid using harsh and greasy cosmetics on your face. Some products may results acne. This form of acne is known as acne cosmetica. Occasionally women who do not have acne can grow acne cosmetica because of makeup wearing.

No, only two times face washing is sufficient. Washing your face too frequently may lead to irritation and dryness and worsen acne. It is recommended by your doctor to use medicated face wash for acne.

The common side effects of Zitfix-M Gel 25 gm are dry skin and application site reactions such as irritation, burning, redness, and itching. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Gokul, Ashok Nagar , Mangalore -06 Karnataka, India.
Other Info - ZIT0252

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.922.pdf
  2. https://www.medicines.org.uk/emc/files/pil.304.pdf

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