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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zita-Piomet 500 Tablet is used to treat type-2 diabetes mellitus. It contains Metformin, Teneligliptin and pioglitazone. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines; Teneligliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas, and pioglitazone works by helping the body make better use of the insulin it produces.

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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zita-Piomet 500 Tablet

Zita-Piomet 500 Tablet is used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.

Zita-Piomet 500 Tablet contains Metformin, Teneligliptin and pioglitazone. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines; Teneligliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas, and pioglitazone works by helping the body make better use of the insulin it produces.

Zita-Piomet 500 Tablet may cause certain common side effects such as stomach upset, hypoglycaemia, nausea, headache, and vomiting. If these side effects persist longer, consult your doctor immediately. Take Zita-Piomet 500 Tablet as prescribed by your doctor.

Zita-Piomet 500 Tablet should be avoided if you are allergic to any of its components. Inform your doctor about your medical history and the medication history, including herbs and supplements, before starting the treatment with Zita-Piomet 500 Tablet to rule out any adverse effects. Let your doctor know if you are pregnant or are breastfeeding before taking Zita-Piomet 500 Tablet . This medicine is not recommended for children under 18 years of age.

Uses of Zita-Piomet 500 Tablet

Zita-Piomet 500 Tablet is used in the treatment of Type 2 diabetes mellitus, especially when blood sugar is not adequately controlled with single or dual therapy. The detailed uses of Zita-Piomet 500 Tablet are as follows:<br/>• Improves insulin sensitivity: Zita-Piomet 500 Tablet helps the body use insulin more effectively, reducing insulin resistance in muscle and fat tissues.<br/>• Enhances insulin secretion: It stimulates the pancreas to release more insulin in response to high blood glucose levels.<br/>• Reduces glucose production and absorption: Zita-Piomet 500 Tablet decreases sugar production in the liver and slows absorption from the intestines, contributing to better glycaemic control.<br/>

Directions for Use

• Take Zita-Piomet 500 Tablet with food to reduce stomach upset.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Zita-Piomet 500 Tablet is a combination medicine used to treat type 2 diabetes. It contains metformin, teneligliptin and pioglitazone. Metformin works by reducing the sugar production by cells in the liver and delays in sugar absorption from the intestines. Also, it increases the body’s sensitivity to insulin. Teneligliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas. Pioglitazone works by helping your body make better use of the insulin it produces. Together, Zita-Piomet 500 Tablet helps control blood sugar levels.

How Zita-Piomet 500 Tablet Works

Zita-Piomet 500 Tablet contains Metformin, Teneligliptin and pioglitazone. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines; Teneligliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas, and pioglitazone works by helping the body make better use of the insulin it produces.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Zita-Piomet 500 Tablet out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zita-Piomet 500 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zita-Piomet 500 Tablet may include hypoglycaemia, severe lactic acidosis, weight gain in a short period, shortness of breath, swelling of the body parts, swelling or pain in the stomach, frequent dry cough or wheezing, difficulty thinking clearly or confusion, fast or racing heartbeat, and increased tiredness. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Zita-Piomet 500 Tablet should be avoided if you are allergic to any medicines or their components. It is not recommended for use in children below 18 years of age. Avoid drinking alcohol while on Zita-Piomet 500 Tablet  as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body). It is unknown whether Zita-Piomet 500 Tablet can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. Inform your doctor if you have any liver/kidney disease, heart problems, and hypertension before taking Zita-Piomet 500 Tablet . Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements, to rule out any side effects. Prolonged intake of Zita-Piomet 500 Tablet may cause acute pancreatitis (swollen pancreas).

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIodamide
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Zita-Piomet 500 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Zita-Piomet 500 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Iopamidol with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopromide
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Iopromide with Zita-Piomet 500 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Zita-Piomet 500 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIomeprol
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Iomeprol with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Ioversol with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Iopentol with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Iohexol with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Iopanoic acid with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Zita-Piomet 500 Tablet:
Co-administration of Ioglycamic acid with Zita-Piomet 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Zita-Piomet 500 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk/exercise for at least 45 minutes.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly, and avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

Avoid consumption of alcohol during treatment with Zita-Piomet 500 Tablet as it can lead to unpleasant side effects.

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Pregnancy

Consult your doctor

There are no adequate studies on the effect of Zita-Piomet 500 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Zita-Piomet 500 Tablet .

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Breast Feeding

Caution

Limited data is available on the effect of Zita-Piomet 500 Tablet on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking Zita-Piomet 500 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe if prescribed

Zita-Piomet 500 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Zita-Piomet 500 Tablet cautiously, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Zita-Piomet 500 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Zita-Piomet 500 Tablet is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

Have a query?

FAQs

Zita-Piomet 500 Tablet is used to treat Type-2 diabetes mellitus.

Zita-Piomet 500 Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus. Type-2 diabetes mellitus is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.

Zita-Piomet 500 Tablet contains Metformin, Teneligliptin and pioglitazone. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines; Teneligliptin works by decreasing the hormones that raise blood glucose levels and increasing insulin release from the pancreas, and pioglitazone works by helping the body make better use of the insulin it produces.

Hypoglycemia/low blood sugar levels could be the side effect of Zita-Piomet 500 Tablet . Consume sugary food such as candy or fruit juice if you experience hypoglycemic symptoms such as dizziness, cold sweats, anxiety, or tremors. Regularly monitor blood glucose levels while taking Zita-Piomet 500 Tablet .

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - ZIT0198

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