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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zipio G1 Capsule is used to treat type 2 diabetes mellitus. It contains Pioglitazone and Glimepiride which work by causing the pancreas to produce more amount of insulin and helping the body to use insulin effectively. This medicine may sometimes cause side effects such as upper respiratory tract infection, headache, sinus infection, muscle pain and pharyngitis. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

FDC Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zipio G1 Capsule

Zipio G1 Capsule belongs to a group of medicines known as 'antidiabetics', used to treat type 2 (non-insulin-dependent) diabetes mellitus. In type 2 diabetes the body doesn't make enough insulin, or the insulin is not effectively used by the body. This is a type of diabetes that usually develops in adulthood. Insulin is a natural substance released by the body to break down the sugar of the body.

Zipio G1 Capsule is a combination of two drugs namely 'Pioglitazone' and 'Glimepiride'. Pioglitazone belongs to the class of thiazolidinedione (TZD) also called 'glitazones' which helps control the level of sugar in your blood by helping your body to make better use of the insulin it produces. Glimepiride belongs to a class of medicines known as 'sulfonylureas', which works by causing the pancreas to produce more amount of insulin and helping the body to use insulin effectively. This drug also works best for individuals whose bodies naturally produce insulin. 

Take Zipio G1 Capsule as suggested by the doctor. You are advised to take Zipio G1 Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain) and pharyngitis. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these undesirable effects persistently.

Zipio G1 Capsule should not be taken if you have type 1 diabetes mellitus, if you are hypersensitive (allergic) to Zipio G1 Capsule or any of the other ingredients of Zipio G1 Capsule , have heart failure or have had heart failure in the past, diabetic ketoacidosis (a complication of diabetes causing rapid weight loss, nausea or vomiting), severe kidney or liver disease, bladder cancer. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeeding. Safety and efficacy of Zipio G1 Capsule in children under 18 years have not been established, so it should not be given to them. Zipio G1 Capsule is safe to taken by elderly persons whose age is 65 or over if prescribed by the doctor.

Uses of Zipio G1 Capsule

Zipio G1 Capsule is used in the treatment of type 2 diabetes mellitus. The detailed uses of Zipio G1 Capsule are as follows:

  • Manages Type 2 Diabetes Mellitus: Zipio G1 Capsule is used to treat type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone or those who are unable to take metformin.
  • Reduces Risk of Diabetes-Related Complications: By effectively controlling blood sugar levels, Zipio G1 Capsule helps reduce the risk of long-term complications such as nerve damage, blindness, kidney problems, and heart disease.

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Directions for Use

  • Zipio G1 Capsule should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Zipio G1 Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Zipio G1 Capsule is an antidiabetic drug used along with a proper diet and exercise to control high blood sugar (hyperglycemia) in patients with type 2 diabetes. Zipio G1 Capsule works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar. Zipio G1 Capsule may be used on its own in patients who are unable to take metformin and where treatment with diet and exercise has failed to control blood sugar. As Zipio G1 Capsule helps to control the high blood sugar levels in the body, so it prevents the risk of blindness, nerve problems, kidney damage and other serious medical issues like a heart attack.

How Zipio G1 Capsule Works

Zipio G1 Capsule is a combination of two drugs namely 'Pioglitazone' and 'Glimepiride'. Pioglitazone belongs to the class of thiazolidinedione (TZD) also called 'glitazones' which helps control the level of sugar in your blood by helping your body to make better use of the insulin it produces. Glimepiride belongs to a class of medicines known as 'sulfonylureas', which works by causing the pancreas to produce more amount of insulin and helping the body to use insulin effectively. This drug also works best for individuals whose bodies naturally produce insulin.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zipio G1 Capsule out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zipio G1 Capsule

Take Zipio G1 Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Overdose may cause severe hypoglycaemia (low blood sugar). Symptoms may include extreme weakness, tremors, nausea, sweating, trouble speaking, fast heartbeats, confusion or seizures. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Zipio G1 Capsule should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Zipio G1 Capsule suddenly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy), and nerve damage (neuropathy). Zipio G1 Capsule is used to lower the blood sugar however if your sugar level gets reduced to a very low level and you start experiencing symptoms including hunger, sweating, dizziness, headache and feeling shaky. To treat such a condition, it is suggested to keep a fast-acting source of sugar in your bag that includes hard candy, raisins, and non-diet soda. Fluid retention (edema) may occur and can lead to congestive heart failure so, combination use with insulin and use in heart failure may increase the risk in patients taking Zipio G1 Capsule . You should not take Zipio G1 Capsule if you have kidney disease, as measured by a blood test. Zipio G1 Capsule , when used with or without insulin, tends to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Increased fractures may be reported in some women taking Zipio G1 Capsule . Patients with bladder cancer and macular edema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using Zipio G1 Capsule .

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins and a quarter with whole grains.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Zipio G1 Capsule to avoid unpleasant side-effects.

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Pregnancy

Caution

Zipio G1 Capsule is not generally recommended in pregnancy. It's not clear whether pioglitazone can harm your unborn baby. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

It is highly recommended to consult your doctor before taking Zipio G1 Capsule .

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Driving

Caution

Zipio G1 Capsule will not affect your ability to drive or use machines but take care if you experience abnormal vision.

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Liver

Caution

Zipio G1 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zipio G1 Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Zipio G1 Capsule in children have not been established. Zipio G1 Capsule is not recommended in children unless prescribed by a child specialist.

FAQs

Zipio G1 Capsule is used to treat type 2 (non-insulin-dependent) diabetes mellitus.

Zipio G1 Capsule is used to lower the blood sugar however if your sugar level gets reduced to a very low level and you start experiencing symptoms including hunger, sweating, dizziness, headache and feeling shaky. To treat such a condition, it is suggested to keep a fast-acting source of sugar in your bag that include hard candy, raisins and non-diet soda and consult your doctor immediately.

Controlling blood sugar in pregnancy becomes very important as it may cause complications in both mother and unborn child. However, the Zipio G1 Capsule should be stopped before few days of the due date, your doctor may switch to other medication.

Zipio G1 Capsule increases the chances of ovulation even if the woman is at her premenopause stage or not getting her regular periods, so it is advised to use an effective birth control method while taking Zipio G1 Capsule .

Zipio G1 Capsule should not be used in certain medical conditions that include diabetic ketoacidosis (dangerously high blood sugar levels), severe heart failure and active bladder cancer.

Country of origin

India

Manufacturer/Marketer address

Fdc Limited, B-8, Midc Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra
Other Info - ZIP0019

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