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compositionComposition:CEFTAROLINE FOSAMIL-600MG
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Prescription Medicine
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It is used in treating skin and skin structure infections and community-acquired pneumonia caused by bacteria. It contains Ceftaroline fosamil, belonging to the novel fifth-generation cephalosporin class of drugs. It works by inhibiting the synthesis of the bacterial cell wall (a protective covering) that is necessary for their survival and killing bacteria. Sometimes, Zinforo 600mg Injection may cause certain side effects, such as diarrhoea, nausea, vomiting, headache, constipation, rash, abdominal pain, and pain at the site of injection.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFTAROLINE FOSAMIL-600MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zinforo 600mg Injection

Zinforo 600mg Injection is a prescription antibiotic given into a vein to treat certain serious bacterial infections in adults and children. It is used for acute bacterial skin and skin structure infections, including infections caused by some resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA), and for community-acquired bacterial pneumonia, an infection of the lungs acquired outside a hospital.

This medicine kills susceptible bacteria by damaging the protective cell wall they need to survive. It does not treat viral infections such as colds or flu. Using antibiotics only when prescribed and completing the recommended treatment helps reduce the risk of the infection returning and bacteria becoming resistant.

Zinforo 600mg Injection is given as an intravenous infusion (slow drip into a vein), usually by a healthcare professional. The dose, frequency, and length of treatment depend on the type and severity of infection, your age, kidney function, and response to treatment. Because it is given directly into the bloodstream, food does not affect its absorption.

Common side effects may include diarrhoea, nausea, headache, or a reaction where the infusion is given. Consult your doctor right away if you develop severe or bloody diarrhoea, difficulty breathing, swelling of the face or throat, unusual bruising or bleeding, unusual tiredness or pale skin, or new fever or signs of infection.

Before treatment, tell your doctor if you have kidney problems, a history of seizures, bowel problems, or allergies to antibiotics. In particular, tell your doctor if you have ever had an allergic reaction to ceftaroline, another cephalosporin, or a penicillin antibiotic, as allergic reactions can sometimes occur across related antibiotics.

Uses of Zinforo 600mg Injection

Your doctor may prescribe Zinforo 600mg Injection to help manage the following bacterial infections:

  • Acute bacterial skin and skin structure infections: Zinforo 600mg Injection treats certain serious bacterial infections of the skin and tissues beneath the skin, including infections caused by susceptible MRSA.
  • Community-acquired bacterial pneumonia: This medicine treats certain bacterial lung infections acquired outside a hospital, helping clear the bacteria responsible for the infection.

Key Benefits

Zinforo 600mg Injection helps treat serious bacterial infections by killing susceptible bacteria and preventing the infection from continuing to spread.

  • Effective against certain resistant bacteria: Ceftaroline can treat skin infections caused by susceptible MRSA, providing an option when resistance limits the usefulness of some other antibiotics.
  • Helps control serious infection: By killing the bacteria causing the infection, treatment can help the body recover and reduce infection-related symptoms.
  • Provides treatment directly into the bloodstream: Intravenous administration provides reliable delivery when treatment with an injectable antibiotic is appropriate.
  • Suitable for different age groups: Ceftaroline may be used in adults and children when prescribed at an appropriate dose for the patient's age, weight, kidney function, and infection.
Side effects of Zinforo 600mg Injection
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Typically, it is given every 12 hours for adults and every 8 hours for children for 5-14 days. However, follow your doctor’s advice regarding the dosage and duration.
  • Zinforo 600mg Injection will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

How Zinforo 600mg Injection Works

Zinforo 600mg Injection contains ceftaroline fosamil, which is converted in the body to ceftaroline, an antibiotic belonging to the cephalosporin group. Ceftaroline attaches to proteins that bacteria use to build their cell wall (the protective layer surrounding the bacterial cell). This weakens the wall and causes susceptible bacteria to die. It can also attach to an altered protein called PBP2a found in MRSA, which allows it to work against certain bacteria that are resistant to some other antibiotics.
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Alcohol

Consult your doctor

It is unknown whether Zinforo 600mg Injection will interact with alcohol or not. Hence, consult your doctor if you have any concerns.

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Pregnancy

Caution

Limited data is available on the effect of Zinforo 600mg Injection in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Zinforo 600mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Zinforo 600mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Zinforo 600mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Zinforo 600mg Injection may cause unwanted effects like dizziness and affect your capacity to drive a vehicle or operate machinery.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Zinforo 600mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Zinforo 600mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Zinforo 600mg Injection is not recommended for use in children as the safety and efficacy are not established.

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Heart

Consult your doctor

Please consult your doctor if you have any heart problems before taking Zinforo 600mg Injection.

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Geriatrics

Safe if prescribed

Zinforo 600mg Injection is generally safe for elderly patients. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Zinforo 600mg Injection

If you receive or use more medicine than prescribed, seek medical advice promptly. Too much ceftaroline, particularly when kidney function is reduced, may increase the risk of serious side effects such as seizures.

Diet & Lifestyle Advise

  • Stay hydrated: Drink enough fluids unless your doctor has advised you to limit your fluid intake, particularly if you have diarrhoea or fever.
  • Get enough rest: Give your body adequate time to rest and recover while the infection is being treated.
  • Eat a balanced diet: Choose nutritious foods that provide enough energy and protein to support recovery.
  • Manage diarrhoea carefully: Do not take medicines for diarrhoea without checking with your doctor, particularly if the diarrhoea is severe, persistent, watery, or bloody.
  • Follow wound-care advice: If you are being treated for a skin infection, keep the affected area clean and follow any dressing or wound-care instructions provided by your healthcare team.
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Have a query?

How Soon It Starts Working

The time required for Zinforo 600mg Injection to start to work: The time required for Zinforo 600mg Injection to show its action is not clinically established. The time for which the effects of Zinforo 600mg Injection last: The duration of action for Zinforo 600mg Injection is not clinically established.

What if you forget to take Zinforo 600mg Injection

If you receive this medicine in a hospital or clinic, your healthcare team will manage your treatment schedule. If you are receiving treatment at home and miss a scheduled dose, contact your doctor, nurse, or pharmacist promptly for instructions. Do not give yourself two doses to make up for a missed dose.

Storage

• Store unopened vials of Zinforo 600mg Injection at room temperature, specifically between 20°C and 25°C (68°F and 77°F).
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Complete the prescribed course: Continue treatment for the full period prescribed, even if you start to feel better, unless your doctor tells you to stop.
  • Tell your doctor about antibiotic allergies: Do not use this medicine if you have had a serious allergic reaction to ceftaroline or another ingredient in the product. Tell your doctor about any previous reaction to cephalosporins or penicillins because these antibiotics are related and cross-reactivity (an allergic reaction to a related antibiotic) can occur.
  • Report severe diarrhoea: Consult your doctor if you develop severe, persistent, watery, or bloody diarrhoea during treatment or after it has finished.
  • Report signs of blood problems: Fever, frequent infections, unusual tiredness, pale skin, dark urine, yellowing of the skin or eyes, unusual bruising, or bleeding should be assessed promptly.
  • Keep monitoring appointments: Your doctor may check your kidney function and blood cell counts, particularly if treatment continues for an extended period or you have kidney problems.
  • Mention a history of seizures: Tell your doctor if you have had seizures, especially if you also have reduced kidney function.
  • Tell healthcare staff about your treatment: Ceftaroline can cause a positive direct Coombs test, a blood test that detects antibodies attached to red blood cells. Tell healthcare professionals that you are receiving this medicine if blood tests are performed.

Drug-Drug Interactions

verifiedApollotooltip
  • Medicines that can affect kidney function: Tell your doctor if you take medicines that may affect your kidneys. Kidney function is important because ceftaroline is mainly removed from the body through the kidneys, and closer monitoring may be needed when kidney function changes.
  • Other antibiotics: More than one antibiotic may sometimes be needed for a serious infection. Your doctor will decide which combination is appropriate based on the infection and your overall health.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Food: No clinically important food interaction is expected because Zinforo 600mg Injection is given directly into a vein. Meals do not affect the absorption of this medicine. Follow any dietary advice given by your healthcare team during recovery.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Zinforo 600mg Injection contains Ceftaroline fosamil, which works by inhibiting the formation of the bacterial cell wall (a protective covering) that is necessary for their survival.
Yes. Zinforo 600mg Injection can cause diarrhoea as a side effect. Mild diarrhoea may occur with antibiotics, but contact your doctor promptly if it becomes severe, persistent, watery, or bloody, or occurs with stomach cramps or fever. Serious antibiotic-associated diarrhoea can occur during treatment or after it has ended. Do not use anti-diarrhoea medicine unless your doctor tells you to.
No, Zinforo 600mg Injection is not used to treat viral infections. Zinforo 600mg Injection is an antibiotic that is used to treat only bacterial infections.
Zinforo 600mg Injection is used to treat certain serious bacterial infections, including acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. It is also active against susceptible MRSA in approved skin infections. It does not treat viral infections such as colds or flu.
For approved acute bacterial skin and skin structure infections, treatment commonly lasts about 5 to 14 days. Your doctor will decide the exact duration based on the severity of the infection and how well you respond.
Treatment for approved community-acquired bacterial pneumonia commonly lasts about 5 to 7 days. The exact duration depends on your condition and response to treatment.
Ceftaroline is active against susceptible MRSA and is approved for certain skin and skin structure infections caused by these bacteria. Your doctor may perform tests to identify the bacteria causing your infection and determine whether this antibiotic is suitable.
Tell your doctor about any previous penicillin allergy before treatment. Penicillins and cephalosporins such as ceftaroline are related antibiotics, so cross-reactivity is possible. Your doctor will consider the type and severity of your previous reaction before deciding whether this medicine is safe for you.
Your doctor may check your kidney function because the kidneys remove ceftaroline from the body. Blood counts may also be checked, especially during longer treatment, because rare problems such as neutropenia or haemolytic anaemia can occur.
No. Ceftaroline is an antibiotic that treats susceptible bacterial infections. It does not work against viruses that cause colds or flu.
No specific direct interaction between ceftaroline and alcohol is well established. However, alcohol may worsen dehydration or make you feel more unwell while recovering from a serious infection. Ask your doctor whether alcohol is appropriate for you.
Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Your doctor will consider the benefits of treating the infection and the available safety information before deciding whether this medicine is appropriate.

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Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - ZIN0420
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